|
US2003199A
(en)
|
1930-05-31 |
1935-05-28 |
Johnson Frank James |
Automatic coal stoker
|
|
US2003149A
(en)
|
1931-05-22 |
1935-05-28 |
Autographic Register Co |
Manifolding
|
|
US2003065A
(en)
|
1931-06-20 |
1935-05-28 |
John R Ditmars |
Composition for coating sheets, fibrous stocks, and the like
|
|
US2004102A
(en)
|
1932-02-24 |
1935-06-11 |
Daniel A Dickey |
Hollow steel propeller construction
|
|
US2004138A
(en)
|
1932-11-30 |
1935-06-11 |
Byers A M Co |
Method of making wrought iron pipe
|
|
US2002165A
(en)
|
1933-07-08 |
1935-05-21 |
Charles A Winslow |
Air cleaner
|
|
US2003187A
(en)
|
1933-10-02 |
1935-05-28 |
Frederick H Shaw |
Automobile radio device
|
|
US2003166A
(en)
|
1933-10-26 |
1935-05-28 |
Zancan Ottavio |
Front drive for motor cars
|
|
US2001051A
(en)
|
1933-12-01 |
1935-05-14 |
Angelina Mariani |
Tamperproof meter box with cutout control and fuse drawer for electric meters
|
|
US2004092A
(en)
|
1933-12-15 |
1935-06-11 |
John L Chaney |
Device for indicating the temperature of liquids
|
|
US2003060A
(en)
|
1934-04-02 |
1935-05-28 |
Ernest L Heckert |
Thermostatic controlling device
|
|
US2667486A
(en)
|
1951-05-24 |
1954-01-26 |
Research Corp |
2,4-diamino pteridine and derivatives
|
|
IL44058A
(en)
|
1973-02-02 |
1978-10-31 |
Ciba Geigy Ag |
3amino-1,2,4-benzotriazine 1,4-di-noxide derivatives, their preparation and compositions for the control of microorganisms containing them
|
|
AU535258B2
(en)
|
1979-08-31 |
1984-03-08 |
Ici Australia Limited |
Benzotriazines
|
|
DE3205638A1
(de)
|
1982-02-17 |
1983-08-25 |
Hoechst Ag, 6230 Frankfurt |
Trisubstituierte pyrimidin-5-carbonsaeuren und deren derivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
|
|
US4490289A
(en)
|
1982-09-16 |
1984-12-25 |
Hoffmann-La Roche Inc. |
Homogeneous human interleukin 2
|
|
US5624925A
(en)
|
1986-09-25 |
1997-04-29 |
Sri International |
1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
|
|
JP2598100B2
(ja)
|
1988-08-31 |
1997-04-09 |
キヤノン株式会社 |
電子写真感光体
|
|
US5214059A
(en)
|
1989-07-03 |
1993-05-25 |
Hoechst-Roussel Pharmaceuticals Incorporated |
2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders
|
|
US5776502A
(en)
|
1989-07-18 |
1998-07-07 |
Oncogene Science, Inc. |
Methods of transcriptionally modulating gene expression
|
|
US5665543A
(en)
|
1989-07-18 |
1997-09-09 |
Oncogene Science, Inc. |
Method of discovering chemicals capable of functioning as gene expression modulators
|
|
US5041430A
(en)
|
1989-09-18 |
1991-08-20 |
Du Pont Mereck Pharmaceutical Company |
Oral anticoagulant/platelet inhibitor low dose formulation
|
|
JPH03127790A
(ja)
|
1989-10-11 |
1991-05-30 |
Morishita Pharmaceut Co Ltd |
Ｎ―（１ｈ―テトラゾール―５―イル）―２―アニリノ―５―ピリミジンカルボキシアミド類及びその合成中間体
|
|
GB9003553D0
(en)
|
1990-02-16 |
1990-04-11 |
Ici Plc |
Herbicidal compositions
|
|
JP2839106B2
(ja)
|
1990-02-19 |
1998-12-16 |
キヤノン株式会社 |
電子写真感光体
|
|
GB9012592D0
(en)
|
1990-06-06 |
1990-07-25 |
Smithkline Beecham Intercredit |
Compounds
|
|
FR2665159B1
(fr)
|
1990-07-24 |
1992-11-13 |
Rhone Poulenc Sante |
Nouveaux derives de la pyridine et de la quinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
IE74711B1
(en)
|
1990-07-27 |
1997-07-30 |
Ici Plc |
Fungicides
|
|
GB9016800D0
(en)
|
1990-07-31 |
1990-09-12 |
Shell Int Research |
Tetrahydropyrimidine derivatives
|
|
DE4025891A1
(de)
|
1990-08-16 |
1992-02-20 |
Bayer Ag |
Pyrimidyl-substituierte acrylsaeureester
|
|
JPH05345780A
(ja)
|
1991-12-24 |
1993-12-27 |
Kumiai Chem Ind Co Ltd |
ピリミジンまたはトリアジン誘導体及び除草剤
|
|
HUT63941A
(en)
|
1992-05-15 |
1993-11-29 |
Hoechst Ag |
Process for producing 4-alkyl-substituted pyrimidine-5-carboxanilide derivatives, and fungicidal compositions comprising same
|
|
US5438130A
(en)
|
1993-01-15 |
1995-08-01 |
Cambridge Neuroscience, Inc. |
Fucosylated guanosine disulfates as excitatory amino acid antagonists
|
|
JPH0741461A
(ja)
|
1993-05-27 |
1995-02-10 |
Eisai Co Ltd |
スルホン酸エステル誘導体
|
|
JPH0782183A
(ja)
|
1993-09-09 |
1995-03-28 |
Canon Inc |
液晶中間体化合物、液晶性化合物、高分子液晶化合物、高分子液晶共重合体化合物、それらの組成物、液晶素子および記録装置
|
|
DE4338704A1
(de)
|
1993-11-12 |
1995-05-18 |
Hoechst Ag |
Stabilisierte Oligonucleotide und deren Verwendung
|
|
US5530000A
(en)
|
1993-12-22 |
1996-06-25 |
Ortho Pharmaceutical Corporation |
Substituted pyrimidinylaminothiazole derivatives useful as platelet aggreggation inhibitors
|
|
GB9506466D0
(en)
|
1994-08-26 |
1995-05-17 |
Prolifix Ltd |
Cell cycle regulated repressor and dna element
|
|
US5597826A
(en)
|
1994-09-14 |
1997-01-28 |
Pfizer Inc. |
Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist
|
|
DE19502912A1
(de)
|
1995-01-31 |
1996-08-01 |
Hoechst Ag |
G-Cap Stabilisierte Oligonucleotide
|
|
US6326487B1
(en)
|
1995-06-05 |
2001-12-04 |
Aventis Pharma Deutschland Gmbh |
3 modified oligonucleotide derivatives
|
|
EP0850228A1
(en)
|
1995-09-01 |
1998-07-01 |
Signal Pharmaceuticals, Inc. |
Pyrimidine carboxamides and related compounds and methods for treating inflammatory conditions
|
|
GB9523675D0
(en)
|
1995-11-20 |
1996-01-24 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
IL125034A0
(en)
|
1995-12-29 |
1999-01-26 |
Smithkline Beecham Corp |
Vitronectin receptor antagonists
|
|
JPH09274290A
(ja)
|
1996-02-07 |
1997-10-21 |
Fuji Photo Film Co Ltd |
ハロゲン化銀写真感光材料用の現像液および処理方法
|
|
US6204260B1
(en)
|
1996-02-23 |
2001-03-20 |
Eli Lilly And Company |
Non-peptidyl vasopressin V1a antagonists
|
|
DE59707681D1
(de)
|
1996-10-28 |
2002-08-14 |
Rolic Ag Zug |
Vernetzbare, photoaktive Silanderivate
|
|
BR9713368A
(pt)
|
1996-11-20 |
2001-09-18 |
Introgen Therapeutics Inc |
Processo melhorado para a produção e a purificação de vetores adenovirais
|
|
JP3734903B2
(ja)
|
1996-11-21 |
2006-01-11 |
富士写真フイルム株式会社 |
現像処理方法
|
|
JPH10153838A
(ja)
|
1996-11-22 |
1998-06-09 |
Fuji Photo Film Co Ltd |
ハロゲン化銀写真感光材料の処理方法
|
|
JP3720931B2
(ja)
|
1996-11-26 |
2005-11-30 |
富士写真フイルム株式会社 |
ハロゲン化銀写真感光材料の処理方法
|
|
ID22290A
(id)
|
1996-12-04 |
1999-09-30 |
Kimberly Clark Co |
Metoda untuk pembuatan kertas yang kuat pada saat basah
|
|
US5935383A
(en)
|
1996-12-04 |
1999-08-10 |
Kimberly-Clark Worldwide, Inc. |
Method for improved wet strength paper
|
|
ES2196396T3
(es)
|
1996-12-23 |
2003-12-16 |
Bristol Myers Squibb Pharma Co |
Compuestos heteroaromaticos de 5 miembros conteniendo oxigeno o azufre como inhibidores del factor xa.
|
|
JPH10207019A
(ja)
|
1997-01-22 |
1998-08-07 |
Fuji Photo Film Co Ltd |
ハロゲン化銀写真感光材料の処理方法
|
|
JPH10213820A
(ja)
|
1997-01-31 |
1998-08-11 |
Canon Inc |
液晶素子及び液晶装置
|
|
DE59807348D1
(de)
|
1997-02-05 |
2003-04-10 |
Rolic Ag Zug |
Photovernetzbare Silanderivate
|
|
GB9705361D0
(en)
|
1997-03-14 |
1997-04-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
JPH10260512A
(ja)
|
1997-03-19 |
1998-09-29 |
Fuji Photo Film Co Ltd |
ハロゲン化銀感光材料の処理方法
|
|
JPH10310583A
(ja)
|
1997-05-09 |
1998-11-24 |
Mitsubishi Chem Corp |
ピリドンアゾ系化合物、感熱転写用色素およびそれを使用した感熱転写材料
|
|
US6070126A
(en)
|
1997-06-13 |
2000-05-30 |
William J. Kokolus |
Immunobiologically-active linear peptides and method of identification
|
|
TW436485B
(en)
|
1997-08-01 |
2001-05-28 |
American Cyanamid Co |
Substituted quinazoline derivatives
|
|
US6635626B1
(en)
|
1997-08-25 |
2003-10-21 |
Bristol-Myers Squibb Co. |
Imidazoquinoxaline protein tyrosine kinase inhibitors
|
|
US6022884A
(en)
|
1997-11-07 |
2000-02-08 |
Amgen Inc. |
Substituted pyridine compounds and methods of use
|
|
JP4135318B2
(ja)
|
1997-12-15 |
2008-08-20 |
アステラス製薬株式会社 |
新規なピリミジン−５−カルボキサミド誘導体
|
|
BR9813835A
(pt)
|
1997-12-22 |
2000-10-10 |
Du Pont Pharm Co |
Composto, composição farmacêutica e método de tratamento ou prevenção de uma desordem tromboembólica
|
|
KR20010041015A
(ko)
|
1998-02-17 |
2001-05-15 |
윌리엄 제이. 리플린 |
항바이러스성 피리미딘 유도체
|
|
BRPI9909191B8
(pt)
|
1998-03-27 |
2021-07-06 |
Janssen Pharmaceutica Nv |
derivados de pirimidina inibidores do hiv, seu uso e composição farmacêutica que os compreende
|
|
SI0945443T1
(en)
|
1998-03-27 |
2003-08-31 |
Janssen Pharmaceutica N.V. |
HIV inhibiting pyrimidine derivatives
|
|
US6685938B1
(en)
|
1998-05-29 |
2004-02-03 |
The Scripps Research Institute |
Methods and compositions useful for modulation of angiogenesis and vascular permeability using SRC or Yes tyrosine kinases
|
|
DE19830181C1
(de)
|
1998-07-06 |
1999-09-30 |
Inter Control Koehler Hermann |
Mehrpolige elektrische Steckverbindung
|
|
US6136971A
(en)
|
1998-07-17 |
2000-10-24 |
Roche Colorado Corporation |
Preparation of sulfonamides
|
|
US6378526B1
(en)
|
1998-08-03 |
2002-04-30 |
Insite Vision, Incorporated |
Methods of ophthalmic administration
|
|
US6297258B1
(en)
|
1998-09-29 |
2001-10-02 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
|
BRPI9914164B8
(pt)
|
1998-09-29 |
2021-05-25 |
American Cyanamid Co |
compostos de 3-ciano quinolina
|
|
NZ510551A
(en)
|
1998-09-29 |
2003-03-28 |
American Cyanamid Co |
Substituted 3-cyanoquinolines useful as protein tyrosine kinases inhibitors
|
|
US6288082B1
(en)
|
1998-09-29 |
2001-09-11 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
|
AU2381600A
(en)
|
1998-12-23 |
2000-07-31 |
Du Pont Pharmaceuticals Company |
Thrombin or factor xa inhibitors
|
|
GB9828511D0
(en)
|
1998-12-24 |
1999-02-17 |
Zeneca Ltd |
Chemical compounds
|
|
EP1150955A2
(en)
|
1999-02-04 |
2001-11-07 |
Millennium Pharmaceuticals, Inc. |
G-protein coupled heptahelical receptor binding compounds and methods of use thereof
|
|
CN101481359A
(zh)
|
1999-04-15 |
2009-07-15 |
布里斯托尔-迈尔斯斯奎布公司 |
环状蛋白酪氨酸激酶抑制剂
|
|
DK1171440T3
(da)
|
1999-04-21 |
2004-08-02 |
Wyeth Corp |
Substituerede 3-cyano-[1,7]-, [1,5]- og [1,8]-naphthyridininhibitorer af tyrosinkinaser
|
|
WO2000071536A1
(en)
|
1999-05-20 |
2000-11-30 |
E.I. Du Pont De Nemours And Company |
Heteroaryloxypyrimidine insecticides and acaricides
|
|
US6710221B1
(en)
|
1999-06-15 |
2004-03-23 |
Kimberly-Clark Worldwide, Inc. |
Absorbent articles incorporating color change graphics
|
|
MXPA02000253A
(es)
|
1999-07-01 |
2002-06-21 |
Ajinomoto Kk |
Compuestos heterociclicos y uso medico de los mismos.
|
|
AU6111000A
(en)
|
1999-07-22 |
2001-02-13 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of viral helcase
|
|
KR20020012309A
(ko)
|
1999-07-23 |
2002-02-15 |
시오노 요시히코 |
Ｔｈ2 분화 억제제
|
|
WO2001007401A1
(en)
|
1999-07-23 |
2001-02-01 |
Shionogi & Co., Ltd. |
Tricyclic compounds and drug compositions containing the same
|
|
IL147913A0
(en)
|
1999-08-12 |
2002-08-14 |
American Cyanamid Co |
Nsaid and efgr kinase inhibitor containing composition for the treatment or inhibition of colonic polyps and colorectal cancer
|
|
US6093838A
(en)
|
1999-08-16 |
2000-07-25 |
Allergan Sales, Inc. |
Amines substituted with a dihydro-benzofuranyl or with a dihydro-isobenzofuranyl group, an aryl or heteroaryl group and an alkyl group, having retinoid-like biological activity
|
|
US6127382A
(en)
|
1999-08-16 |
2000-10-03 |
Allergan Sales, Inc. |
Amines substituted with a tetrahydroquinolinyl group an aryl or heteroaryl group and an alkyl group, having retinoid-like biological activity
|
|
CA2384101A1
(en)
|
1999-09-10 |
2001-03-15 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
GB9922171D0
(en)
|
1999-09-21 |
1999-11-17 |
Zeneca Ltd |
Chemical compounds
|
|
JP2001089412A
(ja)
|
1999-09-22 |
2001-04-03 |
Otsuka Pharmaceut Co Ltd |
ベンゼン誘導体またはその医薬的に許容される塩
|
|
US6506769B2
(en)
|
1999-10-06 |
2003-01-14 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Heterocyclic compounds useful as inhibitors of tyrosine kinases
|
|
US7087597B1
(en)
|
1999-10-12 |
2006-08-08 |
Takeda Pharmaceutical Company Limited |
Pyrimidine 5-carboxamide compounds, process for producing the same and use thereof
|
|
EP1226123A1
(en)
|
1999-11-03 |
2002-07-31 |
Du Pont Pharmaceuticals Company |
Cyano compounds as factor xa inhibitors
|
|
GB9929988D0
(en)
|
1999-12-17 |
2000-02-09 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
JP2003519127A
(ja)
|
1999-12-29 |
2003-06-17 |
ワイス |
三環系タンパクキナーゼ阻害薬
|
|
US6638929B2
(en)
|
1999-12-29 |
2003-10-28 |
Wyeth |
Tricyclic protein kinase inhibitors
|
|
JP2003520855A
(ja)
|
2000-01-28 |
2003-07-08 |
アストラゼネカ アクチボラグ |
化学的化合物
|
|
US6153752A
(en)
|
2000-01-28 |
2000-11-28 |
Creanova, Inc. |
Process for preparing heterocycles
|
|
US20020165244A1
(en)
|
2000-01-31 |
2002-11-07 |
Yuhong Zhou |
Mucin synthesis inhibitors
|
|
AU2001237041B9
(en)
|
2000-02-17 |
2005-07-28 |
Amgen Inc. |
Kinase inhibitors
|
|
WO2001060392A1
(en)
|
2000-02-18 |
2001-08-23 |
Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science |
Oral, nasal and pulmonary dosage formualtions of copolymer 1
|
|
CN1438890A
(zh)
|
2000-02-25 |
2003-08-27 |
弗·哈夫曼-拉罗切有限公司 |
腺苷受体调制剂
|
|
GB0004888D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
US6605615B2
(en)
|
2000-03-01 |
2003-08-12 |
Tularik Inc. |
Hydrazones and analogs as cholesterol lowering agents
|
|
EP1261607B1
(en)
|
2000-03-01 |
2008-11-12 |
Janssen Pharmaceutica N.V. |
2,4-disubstituted thiazolyl derivatives
|
|
GB0004887D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
JP2001247411A
(ja)
|
2000-03-09 |
2001-09-11 |
Tomono Agrica Co Ltd |
有害生物防除剤
|
|
NZ521117A
(en)
|
2000-03-13 |
2005-02-25 |
Wyeth Corp |
Method of treating or inhibiting colonic polyps
|
|
US6613917B1
(en)
|
2000-03-23 |
2003-09-02 |
Allergan, Inc. |
Amines substituted with a dihydronaphthalenyl, chromenyl, or thiochromenyl group, an aryl or heteroaryl group and an alkyl group, having retinoid-like biological activity
|
|
US6608048B2
(en)
|
2000-03-28 |
2003-08-19 |
Wyeth Holdings |
Tricyclic protein kinase inhibitors
|
|
AR028261A1
(es)
|
2000-03-28 |
2003-04-30 |
Wyeth Corp |
Inhibidores triciclicos de la proteina quinasa
|
|
EP1273287A1
(en)
|
2000-04-04 |
2003-01-08 |
Shionogi & Co., Ltd. |
Oily compositions containing highly fat-soluble drugs
|
|
AU2001244610A1
(en)
|
2000-04-05 |
2001-10-23 |
Shionogi And Co., Ltd. |
Oil-in-water microemulsions containing tricyclic compounds or preconcentrates thereof
|
|
US6471968B1
(en)
|
2000-05-12 |
2002-10-29 |
Regents Of The University Of Michigan |
Multifunctional nanodevice platform
|
|
DE10024622A1
(de)
|
2000-05-18 |
2001-11-22 |
Piesteritz Stickstoff |
N-(2-Pyrimidinyl)(thio)phosphorsäuretriamide, Verfahren zu ihrer Herstellung und deren Verwendung als Mittel zur Regulierung bzw. Hemmung der enzymatischen Harnstoff-Hydrolyse
|
|
EP1170353B1
(en)
|
2000-07-06 |
2005-11-02 |
Fuji Photo Film Co., Ltd. |
Liquid crystal composition comprising liquid crystal molecules and aligment promoter
|
|
MXPA03001306A
(es)
|
2000-08-11 |
2003-10-15 |
Boehringer Ingelheim Pharma |
Compuestos heterociclicos utiles como inhibidores de las quinasas de tirosina.
|
|
EP1318814B1
(en)
|
2000-09-15 |
2007-05-30 |
Vertex Pharmaceuticals Incorporated |
Triazole compounds useful as protein kinase inhibitors
|
|
CA2425259A1
(en)
|
2000-10-11 |
2002-04-18 |
Tularik, Inc. |
Modulation of ccr4 function
|
|
AU2001295791A1
(en)
|
2000-11-02 |
2002-05-15 |
Astrazeneca Ab |
4-substituted quinolines as antitumor agents
|
|
EP1337524A1
(en)
|
2000-11-02 |
2003-08-27 |
AstraZeneca AB |
Substituted quinolines as antitumor agents
|
|
WO2002042272A2
(en)
|
2000-11-20 |
2002-05-30 |
Pharmacia Corporation |
Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade
|
|
US20070026433A1
(en)
*
|
2001-03-09 |
2007-02-01 |
Hildebrand William H |
Epitope testing using soluble HLA
|
|
AU2002232919A1
(en)
|
2000-12-29 |
2002-07-16 |
Alteon, Inc. |
Method for treating fibrotic diseases or other indications
|
|
WO2002053160A1
(en)
|
2000-12-29 |
2002-07-11 |
Alteon, Inc. |
Method for treating glaucoma ivb
|
|
JP2002221770A
(ja)
|
2001-01-24 |
2002-08-09 |
Fuji Photo Film Co Ltd |
ハロゲン化銀写真感光材料およびその処理方法
|
|
US20030130264A1
(en)
|
2001-02-16 |
2003-07-10 |
Tularik Inc. |
Methods of using pyrimidine-based antiviral agents
|
|
HRP20030669A2
(en)
|
2001-02-23 |
2005-06-30 |
Merck & Co. Inc. |
N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
|
|
WO2002076438A2
(en)
|
2001-03-23 |
2002-10-03 |
Chugai Seiyaku Kabushiki Kaisha |
Flt-1 ligands and their uses in the treatment of diseases regulatable by angiogenesis
|
|
ES2271322T3
(es)
|
2001-04-13 |
2007-04-16 |
Vertex Pharmaceuticals Incorporated |
Inhibidores de quinasas n-terminales c-jun y otras proteinas quinasa.
|
|
WO2002090347A1
(en)
|
2001-04-30 |
2002-11-14 |
Fujisawa Pharmaceutical Co., Ltd. |
Amide compounds
|
|
MXPA03010269A
(es)
|
2001-05-11 |
2004-05-05 |
Vertex Pharma |
Derivados de 2,5-disubstituida piridina, pirimidina, piridazina y 1,2,4-triazina para usarse como inhibidores de p38.
|
|
WO2002094766A1
(en)
|
2001-05-18 |
2002-11-28 |
Nihon Nohyaku Co., Ltd. |
Phthalamide derivative, agricultural or horticultural insecticide, and use thereof
|
|
EP1401833A2
(fr)
|
2001-05-28 |
2004-03-31 |
Aventis Pharma S.A. |
Derives chimiques et leur application comme agent antitelomerase
|
|
NZ529654A
(en)
|
2001-05-29 |
2005-12-23 |
Schering Ag |
CDK inhibiting pyrimidines, production thereof and their use as medicaments
|
|
US7514098B2
(en)
|
2001-05-30 |
2009-04-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Use of targeted cross-linked nanoparticles for in vivo gene delivery
|
|
ATE339418T1
(de)
|
2001-06-01 |
2006-10-15 |
Vertex Pharma |
Thiazolverbindungen, die sich als inhibitoren von proteinkinasen eignen
|
|
EP1417205B1
(en)
|
2001-07-03 |
2006-08-23 |
Vertex Pharmaceuticals Incorporated |
Isoxazolyl-pyrimidines as inhibitors of src and lck protein kinases
|
|
US6861529B2
(en)
|
2001-07-06 |
2005-03-01 |
Pfizer Inc |
Cycloalkypyrrole-3-carboxylic acid derivatives and heterocycloalkylpyrrole-3-carboxylic acid derivatives
|
|
JO3429B1
(ar)
|
2001-08-13 |
2019-10-20 |
Janssen Pharmaceutica Nv |
مشتقات برميدينات مثبطة فيروس الايدز
|
|
MXPA04002397A
(es)
|
2001-09-14 |
2004-12-02 |
Methylgene Inc |
Inhibidores de histona deacetilasa.
|
|
WO2003030909A1
(en)
|
2001-09-25 |
2003-04-17 |
Bayer Pharmaceuticals Corporation |
2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer
|
|
DE10150615A1
(de)
|
2001-10-12 |
2003-04-30 |
Clariant Gmbh |
Verfahren zur metallorganischen Herstellung organischer Zwischenprodukte
|
|
DE10150614A1
(de)
|
2001-10-12 |
2003-04-30 |
Clariant Gmbh |
Verfahren zur metallorganischen Herstellung organischer Zwischenprodukte über Halogen-Metall-Austauschreaktionen
|
|
DE10150610A1
(de)
|
2001-10-12 |
2003-04-30 |
Clariant Gmbh |
Verfahren zur metallorganischen Herstellung organischer Zwischenprodukte über Amidbasen
|
|
WO2003032994A2
(de)
|
2001-10-17 |
2003-04-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
5-substituierte 4-amino-2-phenylamino-pyrimidinderivate und ihre verwendung als beta-amyloid modulatoren
|
|
PL369259A1
(en)
|
2001-11-01 |
2005-04-18 |
Janssen Pharmaceutica N.V. |
Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors)
|
|
WO2003037869A1
(en)
|
2001-11-01 |
2003-05-08 |
Janssen Pharmaceutica N.V. |
Amide derivatives as glycogen synthase kinase 3-beta inhibitors
|
|
PL370137A1
(en)
|
2001-11-27 |
2005-05-16 |
Wyeth Holdings Corporation |
3-cyanoquinolines as inhibitors of egf-r and her2 kinases
|
|
US20050038035A1
(en)
|
2001-11-28 |
2005-02-17 |
Hisashi Takasugi |
Heterocyclic amide compounds as apolipoprotein b inhibitors
|
|
US20030187026A1
(en)
|
2001-12-13 |
2003-10-02 |
Qun Li |
Kinase inhibitors
|
|
US20030166932A1
(en)
|
2002-01-04 |
2003-09-04 |
Beard Richard L. |
Amines substituted with a dihydronaphthalenyl, chromenyl, or thiochromenyl group, an aryl or heteroaryl group and an alkyl group, having retinoid-like biological activity
|
|
IL162838A0
(en)
|
2002-01-04 |
2005-11-20 |
Univ Rockefeller |
Compositions and methods for prevention and treatment peptide-of amyloid- related disorders
|
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
DE60332915D1
(de)
|
2002-02-05 |
2010-07-22 |
Wyeth Llc |
Verfahren zur herstellung von n-acyl-2-amino-4-alkoxy-5-nitrobenzoesäuren
|
|
MXPA04007637A
(es)
|
2002-02-08 |
2004-11-10 |
Smithkline Beecham Corp |
Compuestos de pirimidina.
|
|
AU2003220970A1
(en)
|
2002-03-01 |
2003-09-16 |
Smithkline Beecham Corporation |
Diamino-pyrimidines and their use as angiogenesis inhibitors
|
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
|
WO2003095448A1
(en)
|
2002-05-06 |
2003-11-20 |
Bayer Pharmaceuticals Corporation |
Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders
|
|
TW200406374A
(en)
|
2002-05-29 |
2004-05-01 |
Novartis Ag |
Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases
|
|
MY141867A
(en)
|
2002-06-20 |
2010-07-16 |
Vertex Pharma |
Substituted pyrimidines useful as protein kinase inhibitors
|
|
MXPA04011849A
(es)
|
2002-07-02 |
2005-03-31 |
Kimberly Clark Co |
Composiciones adhesivas elastomericas y laminados.
|
|
JP4570955B2
(ja)
|
2002-07-09 |
2010-10-27 |
バーテクス ファーマスーティカルズ インコーポレイテッド |
プロテインキナーゼ阻害活性を持つイミダゾール類
|
|
CN103169708B
(zh)
|
2002-07-29 |
2018-02-02 |
里格尔药品股份有限公司 |
用2,4‑嘧啶二胺化合物治疗或者预防自体免疫性疾病的方法
|
|
DE60316810T2
(de)
|
2002-08-02 |
2008-07-17 |
Ab Science |
2-(3-aminoaryl)amino-4-aryl-thiazole und ihre verwendung als c-kit inhibitoren
|
|
MXPA05001804A
(es)
|
2002-08-14 |
2005-05-27 |
Vertex Pharma |
Inhibidores de proteinas cinasas y usos de los mismos.
|
|
UY27939A1
(es)
|
2002-08-21 |
2004-03-31 |
Glaxo Group Ltd |
Compuestos
|
|
DE10240261A1
(de)
|
2002-08-31 |
2004-03-11 |
Clariant Gmbh |
Verfahren zur metallorganischen Herstellung organischer Zwischenprodukte über Halogen-Metall-Austauschreaktionen
|
|
DE10240262A1
(de)
|
2002-08-31 |
2004-03-11 |
Clariant Gmbh |
Verfahren zur metallorganischen Herstellung organischer Zwischenprodukte über Aryllithium-Basen
|
|
CA2500727A1
(en)
|
2002-10-03 |
2004-04-15 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
|
US20050282814A1
(en)
|
2002-10-03 |
2005-12-22 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
|
US20060167021A1
(en)
|
2002-10-04 |
2006-07-27 |
Caritas St. Elizabeth's Medical Center Of Boston, Inc. |
Inhibition of src for treatment of reperfusion injury related to revascularization
|
|
AU2003301662A1
(en)
|
2002-10-21 |
2004-05-13 |
Bristol-Myers Squibb Company |
Quinazolinones and derivatives thereof as factor xa inhibitors
|
|
WO2004037814A1
(en)
|
2002-10-25 |
2004-05-06 |
Vertex Pharmaceuticals Incorporated |
Indazolinone compositions useful as kinase inhibitors
|
|
US7452911B2
(en)
|
2002-10-31 |
2008-11-18 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
|
|
DE10250708A1
(de)
|
2002-10-31 |
2004-05-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
|
|
ES2289349T3
(es)
|
2002-11-04 |
2008-02-01 |
Vertex Pharmaceuticals Incorporated |
Derivados de heteroaril-pirimidina como inhibidores de jak.
|
|
US20050101576A1
(en)
*
|
2003-11-06 |
2005-05-12 |
Novacea, Inc. |
Methods of using vitamin D compounds in the treatment of myelodysplastic syndromes
|
|
US8034831B2
(en)
*
|
2002-11-06 |
2011-10-11 |
Celgene Corporation |
Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
|
|
CA2508601A1
(en)
|
2002-12-06 |
2004-06-24 |
Warner-Lambert Company Llc |
Benzoxazin-3-ones and derivatives thereof as inhibitors of pi3k
|
|
JP3837670B2
(ja)
|
2002-12-12 |
2006-10-25 |
富士通株式会社 |
データ中継装置、連想メモリデバイス、および連想メモリデバイス利用情報検索方法
|
|
CA2507699A1
(en)
|
2002-12-20 |
2004-07-15 |
Pharmacia Corporation |
Heteroarylalkanoic acids as integrin receptor antagonists
|
|
UA80767C2
(en)
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
|
AU2003299600A1
(en)
|
2002-12-20 |
2004-07-29 |
Pharmacia Corpration |
The r-isomer of beta amino acid compounds as integrin receptor antagonists derivatives
|
|
ES2314271T3
(es)
|
2002-12-24 |
2009-03-16 |
Astrazeneca Ab |
Derivados de quinazolina terapeuticos.
|
|
US7144911B2
(en)
|
2002-12-31 |
2006-12-05 |
Deciphera Pharmaceuticals Llc |
Anti-inflammatory medicaments
|
|
EP1597242B1
(en)
|
2003-02-07 |
2008-07-23 |
Janssen Pharmaceutica N.V. |
Hiv inhibiting 1,2,4-triazines
|
|
EA011164B1
(ru)
|
2003-02-07 |
2009-02-27 |
Янссен Фармацевтика Н. В. |
Производные пиримидина для профилактики вич-инфекции
|
|
EP1594512A4
(en)
|
2003-02-11 |
2007-07-11 |
Kemia Inc |
COMPOUNDS FOR THE TREATMENT OF VIRUS INFECTIONS
|
|
CL2004000303A1
(es)
|
2003-02-20 |
2005-04-08 |
Tibotec Pharm Ltd |
Compuestos derivados de pirimidinas y triazinas; proceso de preparacion; composicion farmaceutica; y su uso para inhibir la replicacion del vih.
|
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
|
US20050019395A1
(en)
|
2003-04-14 |
2005-01-27 |
Gabor Pragai |
Formulations of amlodipine maleate
|
|
US20040265375A1
(en)
|
2003-04-16 |
2004-12-30 |
Platteeuw Johannes J. |
Orally disintegrating tablets
|
|
HUE035379T2
(en)
|
2003-04-24 |
2018-05-02 |
Coopervision Int Holding Co Lp |
Hydrogel contact lenses and packaging systems and manufacturing processes for these
|
|
JP4886511B2
(ja)
|
2003-07-30 |
2012-02-29 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
２，４−ピリミジンジアミン化合物による自己免疫疾患の治療または予防方法
|
|
PT1660458E
(pt)
|
2003-08-15 |
2012-04-27 |
Novartis Ag |
2,4-pirimidinodiaminas úteis no tratamento de doenças neoplásicas, desordens inflamatórias e do sistema imunitário
|
|
GB0321710D0
(en)
|
2003-09-16 |
2003-10-15 |
Novartis Ag |
Organic compounds
|
|
US20070105839A1
(en)
|
2003-09-18 |
2007-05-10 |
Patricia Imbach |
2, 4-Di (phenylamino) pyrimidines useful in the treatment of proliferative disorders
|
|
KR20070011458A
(ko)
|
2004-04-08 |
2007-01-24 |
탈자진 인코포레이티드 |
키나제의 벤조트리아진 억제제
|
|
EP2532653A1
(en)
|
2004-08-25 |
2012-12-12 |
Targegen, Inc. |
Benzo[1,2,4]triazines as protein kinase modulators
|
|
US7210697B2
(en)
|
2004-12-16 |
2007-05-01 |
Tricam International, Inc. |
Convertible handle
|
|
EP1841760B1
(en)
|
2004-12-30 |
2011-08-10 |
Exelixis, Inc. |
Pyrimidine derivatives as kinase modulators and method of use
|
|
GT200600008A
(es)
*
|
2005-01-18 |
2006-08-09 |
|
Formulacion de compresion directa y proceso
|
|
GB0501999D0
(en)
|
2005-02-01 |
2005-03-09 |
Sentinel Oncology Ltd |
Pharmaceutical compounds
|
|
JP2008533166A
(ja)
|
2005-03-16 |
2008-08-21 |
ターゲジェン インコーポレーティッド |
ピリミジン化合物および使用法
|
|
WO2006128172A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating b cell regulated autoimmune disorders
|
|
WO2006128129A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating cancer
|
|
JP5225079B2
(ja)
|
2005-06-08 |
2013-07-03 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
Ｊａｋ経路の阻害のための組成物および方法
|
|
BRPI0606172A2
(pt)
|
2005-06-08 |
2009-06-02 |
Targegen Inc |
métodos e composições para o tratamento de distúrbios oculares
|
|
WO2006137658A1
(en)
|
2005-06-20 |
2006-12-28 |
Dongbu Hitek Co., Ltd. |
New substituted 1,3-thiazole derivatives or pharmaceutically acceptable salts thereof having immunosuppression and inflammation inhibitory acitivity, intermediate compounds or pharmaceutically acceptable salts thereof, a process for the preparation thereof, and pharmaceutical composition comprising the same
|
|
WO2007000778A2
(en)
|
2005-06-29 |
2007-01-04 |
Panacea Biotec Ltd. |
Modified release pharmaceutical compositions on the basis of two polymers and processes thereof
|
|
WO2007008541A2
(en)
|
2005-07-08 |
2007-01-18 |
Kalypsys, Inc. |
Cellular cholesterol absorption modifiers
|
|
US7754717B2
(en)
|
2005-08-15 |
2010-07-13 |
Amgen Inc. |
Bis-aryl amide compounds and methods of use
|
|
WO2007038215A1
(en)
|
2005-09-22 |
2007-04-05 |
Incyte Corporation |
Tetracyclic inhibitors of janus kinases
|
|
US20070072682A1
(en)
|
2005-09-29 |
2007-03-29 |
Crawford James T Iii |
Head to head electronic poker game assembly and method of operation
|
|
US8133900B2
(en)
*
|
2005-11-01 |
2012-03-13 |
Targegen, Inc. |
Use of bi-aryl meta-pyrimidine inhibitors of kinases
|
|
UA109412C2
(uk)
*
|
2005-11-01 |
2015-08-25 |
|
5-метил-n2-[4-(4-метилпіперазин-1-іл)феніл]-піримідин-2,4-діамін та його застосування в способі одержання сполуки
|
|
US8604042B2
(en)
|
2005-11-01 |
2013-12-10 |
Targegen, Inc. |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
|
PL1951684T3
(pl)
|
2005-11-01 |
2017-03-31 |
Targegen, Inc. |
Biarylowe meta-pirymidynowe inhibitory kinaz
|
|
US20070161645A1
(en)
|
2005-11-02 |
2007-07-12 |
Targegen, Inc. |
Thiazole inhibitors targeting resistant kinase mutations
|
|
CA2628474A1
(en)
|
2005-11-03 |
2007-05-10 |
Sgx Pharmaceuticals, Inc. |
Pyrimidinyl-thiophene kinase modulators
|
|
EP1954256A2
(en)
|
2005-11-09 |
2008-08-13 |
Torrent Pharmaceuticals Ltd |
Pharmaceutical composition comprising a compound having a catechol moiety and an alkalising agent
|
|
BRPI0618552B8
(pt)
|
2005-11-16 |
2021-05-25 |
Cell Therapeutics Inc |
compostos derivados de pirimidina ligados ao oxigênio,composição farmacêutica que inclui os ditos compostos,método de síntese dos compostos e usos terapêuticos dos mesmos
|
|
EP2474545B1
(en)
|
2005-12-13 |
2016-11-09 |
Incyte Holdings Corporation |
Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
|
|
EA200870217A1
(ru)
*
|
2006-01-30 |
2009-02-27 |
Экселиксис, Инк. |
4-арил-2-аминопиримидины или 4-арил-2-аминоалкилпиримидины в качестве модуляторов jak-2 и содержащие их фармацевтические композиции
|
|
US8962643B2
(en)
|
2006-02-24 |
2015-02-24 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
|
EP2007362B1
(en)
*
|
2006-04-04 |
2018-09-05 |
KG Acquisition LLC |
Oral dosage forms including an antiplatelet agent and an acid inhibitor
|
|
US7691858B2
(en)
|
2006-04-25 |
2010-04-06 |
Targegen, Inc. |
Kinase inhibitors and methods of use thereof
|
|
EP2037918A2
(en)
*
|
2006-05-15 |
2009-03-25 |
Acadia Pharmaceuticals Inc. |
Pharmaceutical formulations of pimavanserin
|
|
US8030487B2
(en)
|
2006-07-07 |
2011-10-04 |
Targegen, Inc. |
2-amino—5-substituted pyrimidine inhibitors
|
|
RU2009105826A
(ru)
|
2006-07-21 |
2010-08-27 |
Новартис АГ (CH) |
2,4-ди(ариламино)питимидин-5-карбоксамидные соединения в качестве ингибиторов jak-киназ
|
|
US20080021013A1
(en)
|
2006-07-21 |
2008-01-24 |
Cephalon, Inc. |
JAK inhibitors for treatment of myeloproliferative disorders
|
|
WO2008057233A2
(en)
*
|
2006-10-25 |
2008-05-15 |
The Regents Of The University Of California |
Models of erythropoiesis
|
|
DK2173752T4
(en)
|
2007-06-13 |
2022-08-01 |
Incyte Holdings Corp |
Salte af janus-kinase-inhibitor (r)-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropannitril
|
|
DE102007034947B4
(de)
*
|
2007-07-26 |
2009-06-18 |
Siemens Ag |
Vorrichtung zum Entladen eines Stapels von auf ihren Schmalseiten stehenden flachen Gegenständen
|
|
EP2179037A4
(en)
*
|
2007-08-21 |
2010-12-22 |
Nodality Inc |
DIAGNOSIS, FORECASTING AND TREATMENT PROCEDURES
|
|
WO2009046416A1
(en)
|
2007-10-05 |
2009-04-09 |
Targegen Inc. |
Anilinopyrimidines as jak kinase inhibitors
|
|
WO2009073575A2
(en)
|
2007-11-30 |
2009-06-11 |
Oregon Health & Science University |
Methods for treating induced cellular proliferative disorders
|
|
KR101390607B1
(ko)
*
|
2008-07-14 |
2014-05-19 |
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|
|
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(en)
|
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|
|
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(pl)
|
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2015-07-31 |
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|
|
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(en)
|
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|
|
US20100278921A1
(en)
*
|
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2010-11-04 |
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|
|
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(en)
|
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|
|
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(ja)
|
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2013-01-10 |
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|