DE60332915D1 - Verfahren zur herstellung von n-acyl-2-amino-4-alkoxy-5-nitrobenzoesäuren - Google Patents
Verfahren zur herstellung von n-acyl-2-amino-4-alkoxy-5-nitrobenzoesäurenInfo
- Publication number
- DE60332915D1 DE60332915D1 DE60332915T DE60332915T DE60332915D1 DE 60332915 D1 DE60332915 D1 DE 60332915D1 DE 60332915 T DE60332915 T DE 60332915T DE 60332915 T DE60332915 T DE 60332915T DE 60332915 D1 DE60332915 D1 DE 60332915D1
- Authority
- DE
- Germany
- Prior art keywords
- alkoxy
- acyl
- amino
- producing
- nitrobenzoic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35477702P | 2002-02-05 | 2002-02-05 | |
| PCT/US2003/003437 WO2003066575A1 (en) | 2002-02-05 | 2003-02-04 | Process for the synthesis of n-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60332915D1 true DE60332915D1 (de) | 2010-07-22 |
Family
ID=27734420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60332915T Expired - Lifetime DE60332915D1 (de) | 2002-02-05 | 2003-02-04 | Verfahren zur herstellung von n-acyl-2-amino-4-alkoxy-5-nitrobenzoesäuren |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7227037B2 (de) |
| EP (1) | EP1472213B1 (de) |
| JP (1) | JP4361375B2 (de) |
| CN (2) | CN1330627C (de) |
| AT (1) | ATE470656T1 (de) |
| AU (1) | AU2003217323A1 (de) |
| BR (1) | BR0307375A (de) |
| CA (1) | CA2475141A1 (de) |
| DE (1) | DE60332915D1 (de) |
| MX (1) | MXPA04007495A (de) |
| WO (1) | WO2003066575A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1330627C (zh) * | 2002-02-05 | 2007-08-08 | 惠氏公司 | N－酰基－2－氨基－4－烷氧基－5－硝基苯甲酸类化合物的合成方法 |
| US7109337B2 (en) | 2002-12-20 | 2006-09-19 | Pfizer Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
| CA2529611C (en) | 2002-12-20 | 2009-12-15 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| JP2007537238A (ja) | 2004-05-14 | 2007-12-20 | ファイザー・プロダクツ・インク | 異常細胞増殖の治療のためのピリミジン誘導体 |
| BRPI0511132A (pt) | 2004-05-14 | 2007-11-27 | Pfizer Prod Inc | derivados de pirimidina e composição farmacêutica compreendendo os mesmos |
| WO2005111022A1 (en) | 2004-05-14 | 2005-11-24 | Pfizer Products Inc. | Pyrimidines derivatives for the treatment of abnormal cell growth |
| BRPI0610142A2 (pt) * | 2005-05-25 | 2011-01-04 | Wyeth Corp | método para preparar um composto da fórmula (i) ; e método para preparar um ácido da fórmula (vii) |
| RU2007139544A (ru) * | 2005-05-25 | 2009-06-27 | Вайет (Us) | Способ получения 3-цианохинолинов и промежуточные соединения, полученные согласно данному способу |
| CN101203494A (zh) * | 2005-05-25 | 2008-06-18 | 惠氏公司 | 合成经取代3-氰基喹啉和其中间物的方法 |
| CA2816957A1 (en) | 2010-11-07 | 2012-05-10 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
| JP6358419B2 (ja) * | 2013-12-27 | 2018-07-18 | 日産化学工業株式会社 | 脂環式テトラカルボン酸の製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2138000A1 (en) * | 1994-01-03 | 1995-07-04 | John E. Starrett, Jr. | Retinoid-like compounds |
| US6002008A (en) * | 1997-04-03 | 1999-12-14 | American Cyanamid Company | Substituted 3-cyano quinolines |
| CN1190197C (zh) * | 2000-03-13 | 2005-02-23 | 惠氏控股公司 | 氰基喹啉用于制备治疗或抑制结肠息肉药物中的用途 |
| CN1330627C (zh) * | 2002-02-05 | 2007-08-08 | 惠氏公司 | N－酰基－2－氨基－4－烷氧基－5－硝基苯甲酸类化合物的合成方法 |
-
2003
- 2003-02-04 CN CNB038032708A patent/CN1330627C/zh not_active Expired - Fee Related
- 2003-02-04 JP JP2003565950A patent/JP4361375B2/ja not_active Expired - Fee Related
- 2003-02-04 WO PCT/US2003/003437 patent/WO2003066575A1/en active Application Filing
- 2003-02-04 DE DE60332915T patent/DE60332915D1/de not_active Expired - Lifetime
- 2003-02-04 BR BR0307375-0A patent/BR0307375A/pt not_active IP Right Cessation
- 2003-02-04 CN CNA2007101042374A patent/CN101050189A/zh active Pending
- 2003-02-04 AU AU2003217323A patent/AU2003217323A1/en not_active Abandoned
- 2003-02-04 EP EP03713366A patent/EP1472213B1/de not_active Expired - Lifetime
- 2003-02-04 AT AT03713366T patent/ATE470656T1/de not_active IP Right Cessation
- 2003-02-04 MX MXPA04007495A patent/MXPA04007495A/es active IP Right Grant
- 2003-02-04 CA CA002475141A patent/CA2475141A1/en not_active Abandoned
- 2003-02-05 US US10/358,847 patent/US7227037B2/en not_active Expired - Fee Related
-
2007
- 2007-05-18 US US11/804,509 patent/US7294740B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1472213A1 (de) | 2004-11-03 |
| US7227037B2 (en) | 2007-06-05 |
| US7294740B2 (en) | 2007-11-13 |
| US20050085662A1 (en) | 2005-04-21 |
| US20070219394A1 (en) | 2007-09-20 |
| WO2003066575A1 (en) | 2003-08-14 |
| MXPA04007495A (es) | 2004-11-10 |
| CN1330627C (zh) | 2007-08-08 |
| CA2475141A1 (en) | 2003-08-14 |
| CN1628093A (zh) | 2005-06-15 |
| EP1472213B1 (de) | 2010-06-09 |
| JP4361375B2 (ja) | 2009-11-11 |
| ATE470656T1 (de) | 2010-06-15 |
| JP2005517005A (ja) | 2005-06-09 |
| BR0307375A (pt) | 2004-12-07 |
| CN101050189A (zh) | 2007-10-10 |
| AU2003217323A1 (en) | 2003-09-02 |
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