DE60332915D1 - Verfahren zur herstellung von n-acyl-2-amino-4-alkoxy-5-nitrobenzoesäuren - Google Patents

Verfahren zur herstellung von n-acyl-2-amino-4-alkoxy-5-nitrobenzoesäuren

Info

Publication number
DE60332915D1
DE60332915D1 DE60332915T DE60332915T DE60332915D1 DE 60332915 D1 DE60332915 D1 DE 60332915D1 DE 60332915 T DE60332915 T DE 60332915T DE 60332915 T DE60332915 T DE 60332915T DE 60332915 D1 DE60332915 D1 DE 60332915D1
Authority
DE
Germany
Prior art keywords
alkoxy
acyl
amino
producing
nitrobenzoic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60332915T
Other languages
English (en)
Inventor
Scott Mason Duncan
Augustine Tobi Osuma
Sylvain Daigneault
Michel Bernatchez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Application granted granted Critical
Publication of DE60332915D1 publication Critical patent/DE60332915D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Quinoline Compounds (AREA)
DE60332915T 2002-02-05 2003-02-04 Verfahren zur herstellung von n-acyl-2-amino-4-alkoxy-5-nitrobenzoesäuren Expired - Lifetime DE60332915D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35477702P 2002-02-05 2002-02-05
PCT/US2003/003437 WO2003066575A1 (en) 2002-02-05 2003-02-04 Process for the synthesis of n-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids

Publications (1)

Publication Number Publication Date
DE60332915D1 true DE60332915D1 (de) 2010-07-22

Family

ID=27734420

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60332915T Expired - Lifetime DE60332915D1 (de) 2002-02-05 2003-02-04 Verfahren zur herstellung von n-acyl-2-amino-4-alkoxy-5-nitrobenzoesäuren

Country Status (11)

Country Link
US (2) US7227037B2 (de)
EP (1) EP1472213B1 (de)
JP (1) JP4361375B2 (de)
CN (2) CN101050189A (de)
AT (1) ATE470656T1 (de)
AU (1) AU2003217323A1 (de)
BR (1) BR0307375A (de)
CA (1) CA2475141A1 (de)
DE (1) DE60332915D1 (de)
MX (1) MXPA04007495A (de)
WO (1) WO2003066575A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04007495A (es) * 2002-02-05 2004-11-10 Wyeth Corp Proceso para sintesis de acidos n-acil2-amino-4-alcoxi-5-nitrobenzoicos.
US7109337B2 (en) 2002-12-20 2006-09-19 Pfizer Inc Pyrimidine derivatives for the treatment of abnormal cell growth
RS20060097A (en) 2002-12-20 2008-11-28 Pfizer Products Inc., Pyrimidine derivatives for the treatment of abnormal cell growth
BRPI0510980A (pt) 2004-05-14 2007-11-27 Pfizer Prod Inc derivados de pirimidina para o tratamento do crescimento anormal de células
MXPA06011658A (es) 2004-05-14 2006-12-14 Pfizer Prod Inc Derivados de pirimidina para el tratamiento del crecimiento celular anormal.
BRPI0510963A (pt) 2004-05-14 2007-11-20 Pfizer Prod Inc derivados pirimidina para o tratamento do crescimento anormal de células
WO2006127205A2 (en) * 2005-05-25 2006-11-30 Wyeth Methods of preparing 3-cyano-quinolines and intermediates made thereby
BRPI0610147A2 (pt) * 2005-05-25 2010-06-01 Wyeth Corp método para preparar e sintetizar 3-cianoquinolinas substituìdas e 4-amino-3-cianoquinolinas
RU2007140957A (ru) * 2005-05-25 2009-06-27 Вайет (Us) Способы синтеза производных 6-алкиламинохинолинов
WO2012060847A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
JP6358419B2 (ja) * 2013-12-27 2018-07-18 日産化学工業株式会社 脂環式テトラカルボン酸の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2138000A1 (en) * 1994-01-03 1995-07-04 John E. Starrett, Jr. Retinoid-like compounds
US6002008A (en) * 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
AU4545201A (en) * 2000-03-13 2001-09-24 American Cyanamid Co Method of treating or inhibiting colonic polyps
MXPA04007495A (es) * 2002-02-05 2004-11-10 Wyeth Corp Proceso para sintesis de acidos n-acil2-amino-4-alcoxi-5-nitrobenzoicos.

Also Published As

Publication number Publication date
CN101050189A (zh) 2007-10-10
US20050085662A1 (en) 2005-04-21
EP1472213A1 (de) 2004-11-03
CN1628093A (zh) 2005-06-15
US20070219394A1 (en) 2007-09-20
ATE470656T1 (de) 2010-06-15
BR0307375A (pt) 2004-12-07
JP4361375B2 (ja) 2009-11-11
MXPA04007495A (es) 2004-11-10
EP1472213B1 (de) 2010-06-09
AU2003217323A1 (en) 2003-09-02
CA2475141A1 (en) 2003-08-14
WO2003066575A1 (en) 2003-08-14
US7227037B2 (en) 2007-06-05
US7294740B2 (en) 2007-11-13
CN1330627C (zh) 2007-08-08
JP2005517005A (ja) 2005-06-09

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