BG60444B2 - Метод за получаване на избран протеин - Google Patents

Метод за получаване на избран протеин Download PDF

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Publication number
BG60444B2
BG60444B2 BG098458A BG9845894A BG60444B2 BG 60444 B2 BG60444 B2 BG 60444B2 BG 098458 A BG098458 A BG 098458A BG 9845894 A BG9845894 A BG 9845894A BG 60444 B2 BG60444 B2 BG 60444B2
Authority
BG
Bulgaria
Prior art keywords
protein
bacterial
polypeptide
gene
periplasmic
Prior art date
Application number
BG098458A
Other languages
Bulgarian (bg)
English (en)
Inventor
Walter Gilbert
Stephanie Broome
Lydia Villa-Komaroff
Argiris Efstratiadis
Original Assignee
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25433372&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG60444(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by President And Fellows Of Harvard College filed Critical President And Fellows Of Harvard College
Publication of BG60444B2 publication Critical patent/BG60444B2/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BG098458A 1978-06-08 1994-02-11 Метод за получаване на избран протеин BG60444B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/913,533 US4411994A (en) 1978-06-08 1978-06-08 Protein synthesis

Publications (1)

Publication Number Publication Date
BG60444B2 true BG60444B2 (bg) 1995-03-31

Family

ID=25433372

Family Applications (1)

Application Number Title Priority Date Filing Date
BG098458A BG60444B2 (bg) 1978-06-08 1994-02-11 Метод за получаване на избран протеин

Country Status (20)

Country Link
US (1) US4411994A (ja)
EP (1) EP0006694B2 (ja)
JP (2) JPS5519092A (ja)
AT (1) ATE5001T1 (ja)
AU (1) AU524856B2 (ja)
BG (1) BG60444B2 (ja)
CA (1) CA1215920A (ja)
DD (1) DD148235A5 (ja)
DE (1) DE2966291D1 (ja)
DK (1) DK237979A (ja)
ES (1) ES481362A1 (ja)
FI (1) FI791841A (ja)
GR (1) GR72953B (ja)
IE (1) IE48156B1 (ja)
IL (1) IL57491A (ja)
MX (1) MX6339E (ja)
NZ (1) NZ190524A (ja)
PT (1) PT69737A (ja)
WO (1) WO1980000030A1 (ja)
ZA (1) ZA792486B (ja)

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CN116096236A (zh) 2020-05-01 2023-05-09 韦斯塔隆公司 杀昆虫组合
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WO2023245128A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial peptide
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Also Published As

Publication number Publication date
EP0006694B1 (en) 1983-10-12
CA1215920A (en) 1986-12-30
JPS61227598A (ja) 1986-10-09
PT69737A (en) 1979-07-01
JPS5519092A (en) 1980-02-09
GR72953B (ja) 1984-01-18
WO1980000030A1 (en) 1980-01-10
IL57491A0 (en) 1979-10-31
AU524856B2 (en) 1982-10-07
ZA792486B (en) 1981-01-28
EP0006694A2 (en) 1980-01-09
DD148235A5 (de) 1981-05-13
NZ190524A (en) 1982-09-14
ATE5001T1 (de) 1983-10-15
EP0006694B2 (en) 1992-01-22
IL57491A (en) 1983-09-30
DE2966291D1 (en) 1983-11-17
IE48156B1 (en) 1984-10-17
IE791115L (en) 1979-12-08
EP0006694A3 (en) 1980-01-23
FI791841A (fi) 1979-12-09
AU4775279A (en) 1979-12-13
US4411994A (en) 1983-10-25
JPS6246160B2 (ja) 1987-09-30
JPH0755151B2 (ja) 1995-06-14
DK237979A (da) 1979-12-09
ES481362A1 (es) 1980-03-01
MX6339E (es) 1985-04-23

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