ES481362A1 - Un metodo de preparar una proteina seleccionada o una parte de la misma. - Google Patents

Un metodo de preparar una proteina seleccionada o una parte de la misma.

Info

Publication number
ES481362A1
ES481362A1 ES481362A ES481362A ES481362A1 ES 481362 A1 ES481362 A1 ES 481362A1 ES 481362 A ES481362 A ES 481362A ES 481362 A ES481362 A ES 481362A ES 481362 A1 ES481362 A1 ES 481362A1
Authority
ES
Spain
Prior art keywords
selected protein
making
cleaved
protein
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481362A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard College
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25433372&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES481362(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Harvard College filed Critical Harvard College
Publication of ES481362A1 publication Critical patent/ES481362A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Un método para preparar una proteína seleccionada o una parte de la misma, insertando ADN que representa la proteína seleccionada o una parte de la misma en un gen bacteriano, caracterizado por escindir el gen bacteriano para una proteína vehículo extracelular o periplásmica, insertar en el lugar escindido por una etapa de recombinación un fragmento de ADN no bacteriano que codifica la proteína seleccionada o una parte de la misma, transformar un huésped bacteriano con el gen recombinado, y cultivar las bacterias transformadas para excretar la proteína seleccionada o una parte de la misma.
ES481362A 1978-06-08 1979-06-07 Un metodo de preparar una proteina seleccionada o una parte de la misma. Expired ES481362A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/913,533 US4411994A (en) 1978-06-08 1978-06-08 Protein synthesis

Publications (1)

Publication Number Publication Date
ES481362A1 true ES481362A1 (es) 1980-03-01

Family

ID=25433372

Family Applications (1)

Application Number Title Priority Date Filing Date
ES481362A Expired ES481362A1 (es) 1978-06-08 1979-06-07 Un metodo de preparar una proteina seleccionada o una parte de la misma.

Country Status (20)

Country Link
US (1) US4411994A (es)
EP (1) EP0006694B2 (es)
JP (2) JPS5519092A (es)
AT (1) ATE5001T1 (es)
AU (1) AU524856B2 (es)
BG (1) BG60444B2 (es)
CA (1) CA1215920A (es)
DD (1) DD148235A5 (es)
DE (1) DE2966291D1 (es)
DK (1) DK237979A (es)
ES (1) ES481362A1 (es)
FI (1) FI791841A (es)
GR (1) GR72953B (es)
IE (1) IE48156B1 (es)
IL (1) IL57491A (es)
MX (1) MX6339E (es)
NZ (1) NZ190524A (es)
PT (1) PT69737A (es)
WO (1) WO1980000030A1 (es)
ZA (1) ZA792486B (es)

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR7807290A (pt) * 1977-11-08 1979-06-12 Genentech Inc Plasmideo,processo para producao de um polipeptido especifico veiculo clonal,cultura bacteriana transformante,processo para produzir uma substancia imunogenica processo para preparar um gene estrutural,e polidesoxirribonucleotido de faixa dupla
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
GR70279B (es) * 1979-09-12 1982-09-03 Univ California
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
US6455275B1 (en) 1980-02-25 2002-09-24 The Trustees Of Columbia University In The City Of New York DNA construct for producing proteinaceous materials in eucaryotic cells
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
US4711843A (en) * 1980-12-31 1987-12-08 Cetus Corporation Method and vector organism for controlled accumulation of cloned heterologous gene products in Bacillus subtilis
AU545912B2 (en) * 1980-03-10 1985-08-08 Cetus Corporation Cloned heterologous jive products in bacillies
YU45104B (en) 1980-04-03 1992-03-10 Biogen Nv Process for producing recombinant dnk molecule, capable of inducting polypeptide expression in an one-cell host
US4338397A (en) * 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
US6610830B1 (en) 1980-07-01 2003-08-26 Hoffman-La Roche Inc. Microbial production of mature human leukocyte interferons
IL63916A0 (en) * 1980-09-25 1981-12-31 Genentech Inc Microbial production of human fibroblast interferon
US4394443A (en) * 1980-12-18 1983-07-19 Yale University Method for cloning genes
FI64813C (fi) * 1980-12-31 1984-01-10 Ilkka Antero Palva Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer
GR76959B (es) * 1981-01-02 1984-09-04 Univ New York State Res Found
NZ199391A (en) * 1981-01-02 1985-12-13 Genentech Inc Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin
US4663285A (en) * 1981-01-06 1987-05-05 The Public Health Laboratory Service Board Chimeric plasmids
ZA824218B (en) * 1981-06-29 1983-04-27 Cetus Corp Plasmid for producing human insulin
JPS5869897A (ja) * 1981-10-20 1983-04-26 Gakuzo Tamura Ｄｎａ遺伝子
EP0078154A3 (en) * 1981-10-28 1985-01-09 The Regents Of The University Of California Plasmids and cells for heterologous expression of metallothioneins and processes for producing and using the metallothionein
US4532207A (en) * 1982-03-19 1985-07-30 G. D. Searle & Co. Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase
US4863855A (en) * 1982-05-14 1989-09-05 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
JPS592689A (ja) * 1982-06-04 1984-01-09 Handai Biseibutsubiyou Kenkyukai 強力な遺伝子発現能を有する新規レプリコンの作成法
US4595658A (en) * 1982-09-13 1986-06-17 The Rockefeller University Method for facilitating externalization of proteins synthesized in bacteria
DE3382547D1 (de) * 1983-01-12 1992-05-27 Chiron Corp Sekretorische expression in eukaryoten.
SE8300693L (sv) * 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
JPS59162874A (ja) * 1983-03-08 1984-09-13 Rikagaku Kenkyusho 微生物の培養方法
US4962055A (en) * 1983-03-08 1990-10-09 Rikagaku Kenkyusho Plasmid, method for construction of the same, microorganisms carrying the plasmid and method for cultivation of the microorganism
DK138984A (da) * 1983-03-08 1984-09-09 Rikagaku Kenkyusho Plasmid, fremgangsmaade til fremstilling heraf, mikroorganismer indeholdende samme samt fremgangsmaade til dyrkning af mikroorganismen
US4711844A (en) * 1983-03-09 1987-12-08 Cetus Corporation Modified signal peptides
US4820642A (en) * 1983-04-04 1989-04-11 The Regents Of The University Of California Amplified expression vector
JPS60501140A (ja) * 1983-04-22 1985-07-25 アムジエン 酵母による外因性ポリペプチドの分泌
US7198919B1 (en) 1983-04-25 2007-04-03 Genentech, Inc. Use of alpha factor sequences in yeast expression systems
EP0123228B1 (en) * 1983-04-25 1993-09-29 Chiron Corporation Hybrid dna synthesis of mature insulin-like growth factors
US4663280A (en) * 1983-05-19 1987-05-05 Public Health Research Institute Of The City Of New York Expression and secretion vectors and method of constructing vectors
GB8314362D0 (en) * 1983-05-24 1983-06-29 Celltech Ltd Polypeptide and protein products
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
FR2549855B1 (fr) * 1983-07-29 1987-03-27 Grp Genie Genetique Sequence nucleotidique codant pour le peptide signal de la toxine diphterique, vecteur contenant cette sequence nucleotidique, leur application a la transformation de micro-organismes et compositions peptidiques obtenues
JPH0646946B2 (ja) * 1984-03-30 1994-06-22 三菱化成株式会社 蛋白の産生方法
US4695542A (en) 1983-10-04 1987-09-22 Dnax Research Institute Of Molecular And Cellular Biology, Inc. cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity
US4703008A (en) * 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
KR850004274A (ko) * 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
PH23920A (en) * 1983-12-20 1990-01-23 Cetus Corp Glucoamylase cdna
IT1185503B (it) * 1984-01-11 1987-11-12 Univ New York Cloni di odna di eritropietina umana
US4859465A (en) * 1984-04-20 1989-08-22 The Regents Of The University Of California Vaccine capable of eliciting multivalent antibodies
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
US6022950A (en) * 1984-06-07 2000-02-08 Seragen, Inc. Hybrid molecules having translocation region and cell-binding region
US5668255A (en) * 1984-06-07 1997-09-16 Seragen, Inc. Hybrid molecules having translocation region and cell-binding region
US4801537A (en) * 1984-06-08 1989-01-31 Genex Corporation Vector for expression of polypeptides in bacilli
US5672347A (en) * 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
JPH062074B2 (ja) * 1984-07-27 1994-01-12 國男 山根 オリゴペプチドの製法
EP0170266B1 (en) * 1984-07-30 1993-03-24 Wakunaga Seiyaku Kabushiki Kaisha Process for producing protein, and vector, recombinant dna and transformant used therefor
JP2524695B2 (ja) * 1984-12-26 1996-08-14 湧永製薬株式会社 蛋白質の製造法
JP2524693B2 (ja) * 1984-07-30 1996-08-14 湧永製薬株式会社 蛋白質の製造法
US5691181A (en) * 1984-08-21 1997-11-25 Celltech Limited DNA encoding lipase from human gastric mucosal tissue
JPS61268183A (ja) * 1985-05-24 1986-11-27 Wakamoto Pharmaceut Co Ltd Ｄｎａ，組換体ｄｎａおよびそれらを含む微生物
JP2624470B2 (ja) * 1984-10-02 1997-06-25 バイオジェン インコーポレイテッド ストレプトアビジン様ポリペプチドの製造
US5272254A (en) * 1984-10-02 1993-12-21 Biogen Inc. Production of streptavidin-like polypeptides
US4963495A (en) * 1984-10-05 1990-10-16 Genentech, Inc. Secretion of heterologous proteins
US5190874A (en) * 1984-12-28 1993-03-02 Rikagaku Kenkyusho Method for producing penicillinase and xylanase
JPH0817702B2 (ja) * 1984-12-28 1996-02-28 理化学研究所 新規プラスミド及びその調製方法並びにそのプラスミドを含有する新規微生物
US4774180A (en) * 1986-02-26 1988-09-27 Massachusetts Institute Of Technology Construction and application of polyproteins
JP2500311B2 (ja) * 1985-03-19 1996-05-29 工業技術院長 蛋白製造法
JP2620852B2 (ja) * 1985-07-30 1997-06-18 理化学研究所 新規プラスミド及びそれにより形質転換された新規微生物
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
USH2055H1 (en) 1985-09-20 2002-12-03 Zymogenetics, Inc. Expression of tissue-type plasminogen activator in bacteria
EP0240550A4 (en) * 1985-09-26 1989-09-19 Genetics Inst LUNG SURFACE ACTIVE PROTEINS.
EP0238645A1 (en) * 1985-10-03 1987-09-30 Biotechnology Research Partners, Ltd. Novel lipoprotein-based drug-delivery systems
GB8529014D0 (en) * 1985-11-25 1986-01-02 Biogen Nv Enhanced secretion of heterologous proteins
JPH0669377B2 (ja) * 1985-11-25 1994-09-07 工業技術院長 Ｄｎａ塩基配列およびベクタ−
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
US5084384A (en) * 1987-04-23 1992-01-28 Monsanto Company Secretion of insulin-like growth factor-I
US5426036A (en) * 1987-05-05 1995-06-20 Hoechst Aktiengesellschaft Processes for the preparation of foreign proteins in streptomycetes
US5066792A (en) * 1987-09-04 1991-11-19 Board Of Regents University Of Texas Gene probe for detection of specific human leukemias
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
AU623698B2 (en) 1988-09-02 1992-05-21 Chiron Corporation Macrophage-derived inflammatory mediator (mip-2)
FR2648713B1 (fr) * 1989-06-26 1994-06-10 Commissariat Energie Atomique Proteines hybrides entre une enzyme extracytoplasmique et une autre proteine, leur procede de preparation, ainsi que leur application comme agent de diagnostic
US7413537B2 (en) * 1989-09-01 2008-08-19 Dyax Corp. Directed evolution of disulfide-bonded micro-proteins
US5578464A (en) * 1989-10-31 1996-11-26 Schering Corporation E. coli secretory strains
US5595900A (en) * 1990-02-14 1997-01-21 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
WO1992006191A1 (en) * 1990-09-28 1992-04-16 Protein Engineering Corporation Proteinaceous anti-dental plaque agents
EP1820858B1 (en) * 1991-03-01 2009-08-12 Dyax Corporation Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof
DE69434492T2 (de) 1993-03-10 2006-07-13 Smithkline Beecham Corp. Phosphodiesterase des menschlichen gehirns
US5691180A (en) * 1994-06-09 1997-11-25 The Regents Of The University Of Michigan DNA sequence encoding N-acetyl-galactosamine-transferase
US5807732A (en) * 1995-02-28 1998-09-15 Lowe; John B. GDP-L-fucose: β-D-galactoside 2-α-L-fucosyltransferases, DNA sequences encoding the same, method for producing the same and a method of genotyping a person
US5770420A (en) * 1995-09-08 1998-06-23 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
US6087128A (en) 1998-02-12 2000-07-11 Ndsu Research Foundation DNA encoding an avian E. coli iss
WO2000024769A2 (en) 1998-10-28 2000-05-04 Genentech, Inc. Process for recovering heterologous polypeptide from bacterial refractile particles
ES2530518T3 (es) * 2003-04-29 2015-03-03 Danisco Us Inc Nueva celulasa 029cel de Bacillus
CN101300335A (zh) * 2003-04-30 2008-11-05 金克克国际有限公司 新颖的杆菌BagCel纤维素酶
US7449318B2 (en) * 2003-04-30 2008-11-11 Danisco A/S, Genencor Division Bacillus mHKcel cellulase
EP1625208A4 (en) * 2003-05-12 2006-10-18 Genencor Int NEW LIPOLYTIC ENZYME LIP2
US20100129862A1 (en) * 2003-05-12 2010-05-27 Jones Brian E Novel lipolytic Enzyme lip1
WO2004101760A2 (en) * 2003-05-12 2004-11-25 Genencor International, Inc. Novel lipolytic enzyme elip
PE20231212A1 (es) 2020-04-20 2023-08-17 Vestaron Corp Polipeptidos variantes proteoliticamente estables de u1-agatoxina-ta1b para el control de plagas
BR112022021470A2 (pt) 2020-05-01 2022-12-20 Vestaron Corp Combinações inseticidas
EP4217373A2 (en) 2020-09-28 2023-08-02 Vestaron Corporation Mu-diguetoxin-dc1a variant polypeptides for pest control
CA3215602A1 (en) 2021-04-01 2022-10-06 Vestaron Corporation Av3 mutant polypeptides for pest control
WO2022212863A1 (en) 2021-04-01 2022-10-06 Vestaron Corporation Liposome formulations for pesticide delivery and methods for producing and using the same
WO2023097309A1 (en) 2021-11-29 2023-06-01 Ironwood Pharmaceuticals, Inc. Pharmaceutical compositions for the treatment of visceral pain
WO2023192924A1 (en) 2022-03-30 2023-10-05 Vestaron Corporation Combinations of av3 mutant polypeptides and bt toxins for pest control
WO2023225555A1 (en) 2022-05-18 2023-11-23 Vestaron Corporation Pesticidal actx peptide variants
WO2023245100A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial ncr13 variant peptides
WO2023245169A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial peptide combinations
WO2023245128A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial peptide
WO2024026406A2 (en) 2022-07-29 2024-02-01 Vestaron Corporation Next Generation ACTX Peptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082613A (en) * 1976-04-23 1978-04-04 The Regents Of The University Of Minnesota Process for the production of insulin by genetically transformed fungal cells
JPS53137215A (en) * 1977-05-06 1978-11-30 Harima Refractories Co Ltd Reparing material of blast oven gate by spray method
NO158880C (no) * 1977-11-08 1988-11-09 Genentech Inc Fremgangsmaate for fremstilling av et spesifikt pattedyrhormon.
BG38165A3 (en) * 1977-11-08 1985-10-15 Genentech Inc,Us Method for preparing recombinant cloning vector suitable for transformation of microbial receptor

Also Published As

Publication number Publication date
AU524856B2 (en) 1982-10-07
JPS6246160B2 (es) 1987-09-30
WO1980000030A1 (en) 1980-01-10
ATE5001T1 (de) 1983-10-15
IL57491A (en) 1983-09-30
EP0006694B1 (en) 1983-10-12
JPS61227598A (ja) 1986-10-09
CA1215920A (en) 1986-12-30
IE48156B1 (en) 1984-10-17
DK237979A (da) 1979-12-09
EP0006694B2 (en) 1992-01-22
ZA792486B (en) 1981-01-28
BG60444B2 (bg) 1995-03-31
AU4775279A (en) 1979-12-13
DE2966291D1 (en) 1983-11-17
GR72953B (es) 1984-01-18
EP0006694A3 (en) 1980-01-23
JPS5519092A (en) 1980-02-09
IE791115L (en) 1979-12-08
FI791841A (fi) 1979-12-09
EP0006694A2 (en) 1980-01-09
JPH0755151B2 (ja) 1995-06-14
MX6339E (es) 1985-04-23
DD148235A5 (de) 1981-05-13
IL57491A0 (en) 1979-10-31
PT69737A (en) 1979-07-01
NZ190524A (en) 1982-09-14
US4411994A (en) 1983-10-25

Similar Documents

Publication Publication Date Title
ES481362A1 (es) Un metodo de preparar una proteina seleccionada o una parte de la misma.
FR2681786B1 (es)
EP0088195A3 (en) Messenger rna, production and use thereof
AU568067B2 (en) Oligonucleotide therapeutic agent and methods of making same
ES8700868A1 (es) Metodo de aislamiento de un fragmento de gen que codifica por lo menos una porcion de una proteina.
MD430C2 (ro) Procedeu de obţinere a interferonelor leucocitare umane
ES8205263A1 (es) Un procedimiento para la produccion de una proteina activadora del piasminogeno.
YU45871B (sh) Polipeptid sa humanim imunointerferonskim (ifn-gama) svojstvima
MY101599A (en) Expression of polypeptides in yeast
ATE178456T1 (de) Verfahren zur kontrolle von lepidoptera
ES474850A1 (es) Mejoras introducidas en un procedimiento para la sintesis depolinucleotidos
ATE82320T1 (de) Verfahren zur ausscheidung von genprodukten in das wachstumsmedium von gram-negativen bakterien.
ATE43139T1 (de) Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon.
JPS56117795A (en) Preparation of l-glutamic acid by fermentation method

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201