AU2017225733A1 - Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore - Google Patents

Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore Download PDF

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Publication number
AU2017225733A1
AU2017225733A1 AU2017225733A AU2017225733A AU2017225733A1 AU 2017225733 A1 AU2017225733 A1 AU 2017225733A1 AU 2017225733 A AU2017225733 A AU 2017225733A AU 2017225733 A AU2017225733 A AU 2017225733A AU 2017225733 A1 AU2017225733 A1 AU 2017225733A1
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Australia
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seq
cell
acid sequence
car
amino acid
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AU2017225733A
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Glenn Dranoff
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Novartis AG
University of Pennsylvania Penn
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Novartis AG
University of Pennsylvania Penn
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C07K2317/622—Single chain antibody (scFv)
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AU2017225733A 2016-03-04 2017-03-03 Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore Abandoned AU2017225733A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662303466P 2016-03-04 2016-03-04
US62/303,466 2016-03-04
PCT/IB2017/051267 WO2017149515A1 (en) 2016-03-04 2017-03-03 Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore

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AU2017225733A1 true AU2017225733A1 (en) 2018-09-27

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US (2) US20200281973A1 (enExample)
EP (1) EP3423482A1 (enExample)
JP (1) JP2019513347A (enExample)
KR (1) KR20180118175A (enExample)
CN (1) CN109153714A (enExample)
AU (1) AU2017225733A1 (enExample)
BR (1) BR112018067679A2 (enExample)
CA (1) CA3016287A1 (enExample)
IL (1) IL261525A (enExample)
MX (1) MX2018010733A (enExample)
RU (1) RU2018134771A (enExample)
SG (1) SG11201807489PA (enExample)
WO (1) WO2017149515A1 (enExample)

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JP7162530B2 (ja) * 2015-08-07 2022-10-28 シアトル チルドレンズ ホスピタル （ディービーエイ シアトル チルドレンズ リサーチ インスティテュート） 固形腫瘍を標的とする二重特異性ｃａｒ ｔ細胞

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JP2019513347A (ja) 2019-05-30
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US20200281973A1 (en) 2020-09-10
KR20180118175A (ko) 2018-10-30
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US20240139244A1 (en) 2024-05-02
EP3423482A1 (en) 2019-01-09
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