ATE348601T1 - Im munde zerfallende tablette enthaltend ein benzimidazole - Google Patents

Im munde zerfallende tablette enthaltend ein benzimidazole

Info

Publication number
ATE348601T1
ATE348601T1 AT99919614T AT99919614T ATE348601T1 AT E348601 T1 ATE348601 T1 AT E348601T1 AT 99919614 T AT99919614 T AT 99919614T AT 99919614 T AT99919614 T AT 99919614T AT E348601 T1 ATE348601 T1 AT E348601T1
Authority
AT
Austria
Prior art keywords
administered
fine granules
tablet
average particle
particle diameter
Prior art date
Application number
AT99919614T
Other languages
English (en)
Inventor
Toshihiro Shimizu
Shuji Morimoto
Tetsuro Tabata
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27518561&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE348601(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE348601T1 publication Critical patent/ATE348601T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT99919614T 1998-05-18 1999-05-17 Im munde zerfallende tablette enthaltend ein benzimidazole ATE348601T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP13547298 1998-05-18
JP21926698 1998-08-03
JP22215198 1998-08-05
JP514499 1999-01-12
JP1585199 1999-01-25

Publications (1)

Publication Number Publication Date
ATE348601T1 true ATE348601T1 (de) 2007-01-15

Family

ID=27518561

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99919614T ATE348601T1 (de) 1998-05-18 1999-05-17 Im munde zerfallende tablette enthaltend ein benzimidazole

Country Status (16)

Country Link
US (5) US6328994B1 (de)
EP (3) EP1121103B1 (de)
JP (2) JP3746167B2 (de)
KR (2) KR100554924B1 (de)
CN (1) CN1195500C (de)
AT (1) ATE348601T1 (de)
AU (1) AU3731699A (de)
CA (2) CA2587022A1 (de)
CY (2) CY1105908T1 (de)
DE (1) DE69934505T2 (de)
DK (3) DK2263660T3 (de)
ES (2) ES2274625T3 (de)
HK (2) HK1096021A1 (de)
PT (3) PT1121103E (de)
TW (1) TWI243062B (de)
WO (1) WO1999059544A2 (de)

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CA2323680C (en) 2007-05-22
CY1119153T1 (el) 2018-02-14
KR101032289B1 (ko) 2011-05-06
JP3746167B2 (ja) 2006-02-15
JP2000281564A (ja) 2000-10-10
TWI243062B (en) 2005-11-11
WO1999059544A3 (en) 2001-05-03
DK1736144T3 (en) 2015-12-07
EP1736144A3 (de) 2010-12-29
DK1121103T3 (da) 2007-04-30
WO1999059544A2 (en) 1999-11-25
KR20010042940A (ko) 2001-05-25
US9901546B2 (en) 2018-02-27
EP1121103A2 (de) 2001-08-08
CA2323680A1 (en) 1999-11-25
EP2263660A3 (de) 2011-10-19
DE69934505D1 (de) 2007-02-01
KR20050010070A (ko) 2005-01-26
EP2263660A2 (de) 2010-12-22
HK1096021A1 (zh) 2007-05-25
PT1736144E (pt) 2016-02-10
AU3731699A (en) 1999-12-06
US7875292B2 (en) 2011-01-25
CN1311669A (zh) 2001-09-05
ES2559766T3 (es) 2016-02-15
EP1121103B1 (de) 2006-12-20
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EP1736144B1 (de) 2015-11-11
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CN1195500C (zh) 2005-04-06
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US20110081412A1 (en) 2011-04-07
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PT2263660T (pt) 2017-12-19
US6328994B1 (en) 2001-12-11
WO1999059544A9 (en) 2008-02-21
EP1736144A2 (de) 2006-12-27
US20140271856A1 (en) 2014-09-18
EP2263660B1 (de) 2017-09-27
PT1121103E (pt) 2007-02-28
CA2587022A1 (en) 1999-11-25

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