EP1930030A1 - Puls-präparat mit verbesserten zerfallseigenschaften in vivo - Google Patents
Puls-präparat mit verbesserten zerfallseigenschaften in vivo Download PDFInfo
- Publication number
- EP1930030A1 EP1930030A1 EP06810638A EP06810638A EP1930030A1 EP 1930030 A1 EP1930030 A1 EP 1930030A1 EP 06810638 A EP06810638 A EP 06810638A EP 06810638 A EP06810638 A EP 06810638A EP 1930030 A1 EP1930030 A1 EP 1930030A1
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- European Patent Office
- Prior art keywords
- coating
- pulsed
- release
- enteric
- core
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005283700 | 2005-09-29 | ||
| PCT/JP2006/319147 WO2007037259A1 (ja) | 2005-09-29 | 2006-09-27 | 生体内での崩壊性を向上させたパルス製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP1930030A1 true EP1930030A1 (de) | 2008-06-11 |
Family
ID=37899683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP06810638A Withdrawn EP1930030A1 (de) | 2005-09-29 | 2006-09-27 | Puls-präparat mit verbesserten zerfallseigenschaften in vivo |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20090148519A1 (de) |
| EP (1) | EP1930030A1 (de) |
| JP (1) | JPWO2007037259A1 (de) |
| WO (1) | WO2007037259A1 (de) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008062320A3 (en) * | 2006-10-06 | 2008-11-27 | Eisai Co Ltd | Extended release formulations of a proton pump inhibitor |
| EP2384745A3 (de) * | 2010-05-05 | 2012-01-18 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmazeutische Zusammensetzungen mit modifizierter Freisetzung aus Dexlansoprazol |
| WO2012111024A1 (en) * | 2011-02-18 | 2012-08-23 | Suven Nishtaa Pharma Pvt Ltd | Pharmaceutical compositions of dexlansoprazole |
| BE1024339B1 (fr) * | 2016-07-01 | 2018-01-29 | Be Pharbel Mfg Sa | Microparticules multicouches libérant un composé pharmaceutiquement actif dans une forme pharmaceutique liquide |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050163846A1 (en) * | 2001-11-21 | 2005-07-28 | Eisai Co., Ltd. | Preparation composition containing acid-unstable physiologically active compound, and process for producing same |
| CN1938026A (zh) * | 2004-03-26 | 2007-03-28 | 卫材R&D管理有限公司 | 控释制剂及其制造方法 |
| EP1872778A1 (de) * | 2006-06-29 | 2008-01-02 | LEK Pharmaceuticals D.D. | Stabile pharmazeutische Formulierung enthaltend Rabeprazol-Natrium |
| WO2009113703A2 (en) * | 2008-03-11 | 2009-09-17 | Takeda Pharmaceutical Company Limited | Orally-disintegrating solid preparation |
| JP5813391B2 (ja) * | 2011-06-24 | 2015-11-17 | 日東電工株式会社 | 粒子製剤の製造方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2336218C3 (de) * | 1973-07-17 | 1985-11-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Orale Arzneiform |
| FR2471186A1 (fr) * | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation |
| JPS5846019A (ja) * | 1981-09-14 | 1983-03-17 | Kanebo Ltd | 持続性ニフエジピン製剤 |
| US4863744A (en) * | 1984-09-17 | 1989-09-05 | Alza Corporation | Intestine drug delivery |
| US4892742A (en) * | 1985-11-18 | 1990-01-09 | Hoffmann-La Roche Inc. | Controlled release compositions with zero order release |
| JPH0768125B2 (ja) * | 1988-05-18 | 1995-07-26 | エーザイ株式会社 | 酸不安定化合物の内服用製剤 |
| DE3822095A1 (de) * | 1988-06-30 | 1990-01-04 | Klinge Co Chem Pharm Fab | Neue arzneimittelformulierung sowie verfahren zu deren herstellung |
| US5229131A (en) * | 1990-02-05 | 1993-07-20 | University Of Michigan | Pulsatile drug delivery system |
| KR930006431B1 (ko) * | 1990-10-11 | 1993-07-16 | 재단법인 한국화학연구소 | 약물의 미세캡슐화 방법 |
| YU48263B (sh) * | 1991-06-17 | 1997-09-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh. | Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola |
| US5260068A (en) * | 1992-05-04 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Multiparticulate pulsatile drug delivery system |
| FR2692146B1 (fr) * | 1992-06-16 | 1995-06-02 | Ethypharm Sa | Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention. |
| US5260069A (en) * | 1992-11-27 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Pulsatile particles drug delivery system |
| WO1996019974A1 (fr) * | 1994-12-27 | 1996-07-04 | Kanebo, Ltd. | Preparation a liberation prolongee |
| US5567441A (en) * | 1995-03-24 | 1996-10-22 | Andrx Pharmaceuticals Inc. | Diltiazem controlled release formulation |
| ES2137862B1 (es) * | 1997-07-31 | 2000-09-16 | Intexim S A | Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion. |
| US6296876B1 (en) * | 1997-10-06 | 2001-10-02 | Isa Odidi | Pharmaceutical formulations for acid labile substances |
| SE9704870D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
| JP4127740B2 (ja) * | 1998-04-20 | 2008-07-30 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 安定化したベンズイミダゾール系化合物含有組成物 |
| DK1736144T3 (en) * | 1998-05-18 | 2015-12-07 | Takeda Pharmaceutical | Orally disintegrating tablets. |
| SE9803772D0 (sv) * | 1998-11-05 | 1998-11-05 | Astra Ab | Pharmaceutical formulation |
| US6183766B1 (en) * | 1999-02-12 | 2001-02-06 | The Procter & Gamble Company | Skin sanitizing compositions |
| US6174902B1 (en) * | 1999-04-28 | 2001-01-16 | Sepracor Inc. | R-rabeprazole compositions and methods |
| US6369087B1 (en) * | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| DK1222922T3 (da) * | 1999-10-20 | 2007-12-03 | Eisai R&D Man Co Ltd | Fremgangsmåde til stabilisering af benzimidazolforbindelser |
| US6627223B2 (en) * | 2000-02-11 | 2003-09-30 | Eurand Pharmaceuticals Ltd. | Timed pulsatile drug delivery systems |
| JP2001270827A (ja) * | 2000-03-23 | 2001-10-02 | Eisai Co Ltd | ベンズイミダゾール系化合物含有錠剤 |
| US20020045184A1 (en) * | 2000-10-02 | 2002-04-18 | Chih-Ming Chen | Packaging system |
| US20050163846A1 (en) * | 2001-11-21 | 2005-07-28 | Eisai Co., Ltd. | Preparation composition containing acid-unstable physiologically active compound, and process for producing same |
| JP2003171277A (ja) * | 2001-12-07 | 2003-06-17 | Wyeth Lederle Japan Ltd | 薬物放出時間制御型固形製剤 |
| DE60212464T2 (de) * | 2002-04-29 | 2007-01-11 | EGIS Gyógyszergyár Rt. | Herstellung von tabletten von pharmazeutisch aktiven substanzen mit ungünstigen tablettierungseigenschaften mit einer mikrokristalline zellulose enthaltenden granulierflüssigkeit |
| CA2558535A1 (en) * | 2004-03-03 | 2005-10-06 | Teva Pharmaceutical Industries Ltd. | A stable pharmaceutical composition comprising an acid labile drug |
| CN1938026A (zh) * | 2004-03-26 | 2007-03-28 | 卫材R&D管理有限公司 | 控释制剂及其制造方法 |
-
2006
- 2006-09-27 JP JP2007537636A patent/JPWO2007037259A1/ja not_active Withdrawn
- 2006-09-27 US US12/088,080 patent/US20090148519A1/en not_active Abandoned
- 2006-09-27 EP EP06810638A patent/EP1930030A1/de not_active Withdrawn
- 2006-09-27 WO PCT/JP2006/319147 patent/WO2007037259A1/ja active Application Filing
Non-Patent Citations (1)
| Title |
|---|
| See references of WO2007037259A1 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008062320A3 (en) * | 2006-10-06 | 2008-11-27 | Eisai Co Ltd | Extended release formulations of a proton pump inhibitor |
| EP2384745A3 (de) * | 2010-05-05 | 2012-01-18 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmazeutische Zusammensetzungen mit modifizierter Freisetzung aus Dexlansoprazol |
| US8741345B2 (en) | 2010-05-05 | 2014-06-03 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Modified release pharmaceutical compositions of dexlansoprazole |
| US9114085B2 (en) | 2010-05-05 | 2015-08-25 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Modified release pharmaceutical compositions of dexlansoprazole |
| WO2012111024A1 (en) * | 2011-02-18 | 2012-08-23 | Suven Nishtaa Pharma Pvt Ltd | Pharmaceutical compositions of dexlansoprazole |
| BE1024339B1 (fr) * | 2016-07-01 | 2018-01-29 | Be Pharbel Mfg Sa | Microparticules multicouches libérant un composé pharmaceutiquement actif dans une forme pharmaceutique liquide |
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2007037259A1 (ja) | 2009-04-09 |
| US20090148519A1 (en) | 2009-06-11 |
| WO2007037259A1 (ja) | 2007-04-05 |
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