BRPI0509135A - composição farmacêutica de liberação controlada e método para produzir a mesma - Google Patents
composição farmacêutica de liberação controlada e método para produzir a mesmaInfo
- Publication number
- BRPI0509135A BRPI0509135A BRPI0509135-7A BRPI0509135A BRPI0509135A BR PI0509135 A BRPI0509135 A BR PI0509135A BR PI0509135 A BRPI0509135 A BR PI0509135A BR PI0509135 A BRPI0509135 A BR PI0509135A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- controlled release
- release pharmaceutical
- producing
- same
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
COMPOSIçãO FARMACêTICA DE LIBERAçãO CONTROLADA E MéTODO PARA PRODUZIRA MESMA. é um objeto da presente invenção, no caso uma composição farmacêutica de liberação controlada, particularmente uma composição farmacêutica de liberação por pulso, contendo uma substância ativa fisiologicamente instável em ácido, para prover uma composição farmacêutica que tem pequena variação em tempo de latência de dissolução e alta confiabilidade de características de dissolução. A presente invenção descreve uma composição farmacêutica de liberação controlada compreendendo: a) um núcleo que contém uma substância ativa fisiologicamente instável em ácido e um desintegrante; b) um revestimento de controle de liberação que reveste o núcleo, e que contém um polímero insolúvel em água, um polímero entérico e uma cera hidrofóbica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004093506 | 2004-03-26 | ||
PCT/JP2005/005217 WO2005092336A1 (ja) | 2004-03-26 | 2005-03-23 | 溶出制御製剤とその製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0509135A true BRPI0509135A (pt) | 2007-08-28 |
Family
ID=35055974
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0509135-7A BRPI0509135A (pt) | 2004-03-26 | 2005-03-23 | composição farmacêutica de liberação controlada e método para produzir a mesma |
Country Status (17)
Country | Link |
---|---|
US (2) | US20080095839A1 (pt) |
EP (1) | EP1728512A1 (pt) |
JP (1) | JPWO2005092336A1 (pt) |
KR (1) | KR100794078B1 (pt) |
CN (1) | CN1938026A (pt) |
AU (1) | AU2005225283B2 (pt) |
BR (1) | BRPI0509135A (pt) |
CA (1) | CA2557791C (pt) |
IL (1) | IL177087A (pt) |
MX (1) | MXPA06010785A (pt) |
MY (1) | MY139427A (pt) |
NO (1) | NO20064874L (pt) |
NZ (1) | NZ549838A (pt) |
RU (1) | RU2337687C2 (pt) |
TW (1) | TW200602085A (pt) |
WO (1) | WO2005092336A1 (pt) |
ZA (1) | ZA200607603B (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050163846A1 (en) * | 2001-11-21 | 2005-07-28 | Eisai Co., Ltd. | Preparation composition containing acid-unstable physiologically active compound, and process for producing same |
EP1728512A1 (en) * | 2004-03-26 | 2006-12-06 | Eisai R&D Management Co., Ltd. | Controlled-leaching preparation and process for producing the same |
US8461187B2 (en) | 2004-06-16 | 2013-06-11 | Takeda Pharmaceuticals U.S.A., Inc. | Multiple PPI dosage form |
US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
US8481565B2 (en) | 2004-12-27 | 2013-07-09 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
US20090148519A1 (en) * | 2005-09-29 | 2009-06-11 | Yasuhiro Zaima | Pulsed-release preparation having improved disintegration properties in vivo |
EP1872778A1 (en) * | 2006-06-29 | 2008-01-02 | LEK Pharmaceuticals D.D. | Stable pharmaceutical composition with rabeprazole sodium |
DE102006035549A1 (de) * | 2006-07-27 | 2008-01-31 | Evonik Röhm Gmbh | Arzneiform mit mindestens zweischichtiger Trennschicht |
WO2008015530A2 (en) * | 2006-08-03 | 2008-02-07 | Aurobindo Pharma Limited | Stable solid oral formulation of pantoprazole |
US20100105738A1 (en) * | 2006-10-06 | 2010-04-29 | Mitsuru Mizuno | Extended release formulations of a proton pump inhibitor |
ES2692437T3 (es) | 2007-08-13 | 2018-12-03 | Abuse Deterrent Pharmaceutical Llc | Fármacos resistentes al abuso, método de uso y método de preparación |
JP2009191036A (ja) * | 2008-02-15 | 2009-08-27 | Ss Pharmaceut Co Ltd | 時限放出製剤 |
JP4864024B2 (ja) * | 2008-02-15 | 2012-01-25 | エスエス製薬株式会社 | 時限放出製剤 |
JP2009191034A (ja) * | 2008-02-15 | 2009-08-27 | Ss Pharmaceut Co Ltd | 時限放出製剤 |
EP2255794A1 (en) * | 2009-05-29 | 2010-12-01 | H e x a l Aktiengesellschaft | Enteric coating |
JP5503192B2 (ja) * | 2009-06-03 | 2014-05-28 | 大原薬品工業株式会社 | 生理活性物質含有粒子の製造方法 |
EP2459177A1 (en) * | 2009-07-30 | 2012-06-06 | Evonik Röhm GmbH | Composition comprising an anionic polymeric material and the salt of a saturated monocarboxylic acid having 6 to 22 carbon atoms |
US8962020B2 (en) * | 2012-07-26 | 2015-02-24 | Glycadia Inc. | Long-acting and controlled release formulations of 2-[(3-chlorophenyl) amino] phenylacetic acid |
JP2014122328A (ja) * | 2012-11-22 | 2014-07-03 | Shin Etsu Chem Co Ltd | 押出成形機又は射出成形機洗浄用組成物及び押出成形機又は射出成形機の洗浄方法 |
US20140275149A1 (en) | 2013-03-15 | 2014-09-18 | Inspirion Delivery Technologies, Llc | Abuse deterrent compositions and methods of use |
CN103976972B (zh) * | 2014-05-26 | 2017-09-12 | 中国药科大学 | 酒石酸唑吡坦口服脉冲控释给药系统及其制备方法 |
US10729685B2 (en) | 2014-09-15 | 2020-08-04 | Ohemo Life Sciences Inc. | Orally administrable compositions and methods of deterring abuse by intranasal administration |
EP3117824A1 (en) | 2015-07-17 | 2017-01-18 | BE Pharbel Manufacturing | Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form |
LT3324948T (lt) | 2015-07-17 | 2023-03-27 | BE Pharbel Manufacturing | Daugiasluoksnės farmaciniu požiūriu aktyvaus junginio atpalaidavimo mikrodalelės skystoje vaisto formoje |
CN105796532B (zh) * | 2016-03-28 | 2018-12-21 | 中国医药集团总公司四川抗菌素工业研究所 | 一种雷贝拉唑钠缓释胶囊及其制备方法 |
CN113395960A (zh) * | 2018-11-19 | 2021-09-14 | 爵士制药爱尔兰有限公司 | 抗酒精药物制剂 |
KR20210071242A (ko) * | 2019-12-06 | 2021-06-16 | 진양제약주식회사 | 제약 조성물 |
CN113069428B (zh) * | 2021-04-02 | 2023-02-10 | 珠海润都制药股份有限公司 | 一种雷贝拉唑钠肠溶片的制备方法 |
KR102647279B1 (ko) | 2021-04-08 | 2024-03-18 | 대한뉴팜(주) | 라베프라졸의 우수한 방출 특성을 갖는 라베프라졸 나트륨 및 산화마그네슘을 포함하는 제제 및 이의 제조방법 |
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DE2336218C3 (de) * | 1973-07-17 | 1985-11-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Orale Arzneiform |
FR2471186A1 (fr) * | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation |
JPS5846019A (ja) * | 1981-09-14 | 1983-03-17 | Kanebo Ltd | 持続性ニフエジピン製剤 |
US4863744A (en) * | 1984-09-17 | 1989-09-05 | Alza Corporation | Intestine drug delivery |
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JPH0768125B2 (ja) * | 1988-05-18 | 1995-07-26 | エーザイ株式会社 | 酸不安定化合物の内服用製剤 |
DE3822095A1 (de) * | 1988-06-30 | 1990-01-04 | Klinge Co Chem Pharm Fab | Neue arzneimittelformulierung sowie verfahren zu deren herstellung |
US5229131A (en) * | 1990-02-05 | 1993-07-20 | University Of Michigan | Pulsatile drug delivery system |
KR930006431B1 (ko) * | 1990-10-11 | 1993-07-16 | 재단법인 한국화학연구소 | 약물의 미세캡슐화 방법 |
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US6183766B1 (en) * | 1999-02-12 | 2001-02-06 | The Procter & Gamble Company | Skin sanitizing compositions |
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JP2001055322A (ja) * | 1999-08-18 | 2001-02-27 | Tanabe Seiyaku Co Ltd | パルス放出型製剤 |
US6369087B1 (en) * | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
KR20020038759A (ko) * | 1999-10-20 | 2002-05-23 | 다니구치 미즈오 | 벤즈이미다졸계 화합물 안정화 방법 |
US6627223B2 (en) * | 2000-02-11 | 2003-09-30 | Eurand Pharmaceuticals Ltd. | Timed pulsatile drug delivery systems |
US20020045184A1 (en) * | 2000-10-02 | 2002-04-18 | Chih-Ming Chen | Packaging system |
US20050163846A1 (en) * | 2001-11-21 | 2005-07-28 | Eisai Co., Ltd. | Preparation composition containing acid-unstable physiologically active compound, and process for producing same |
BR0214372A (pt) | 2001-11-21 | 2004-10-26 | Eisai Co Ltd | Composição de um preparado contendo um composto ácido-instavel fisiologicamente ativo e processo para a produção da mesma |
CZ296100B6 (cs) * | 2002-04-29 | 2006-01-11 | EGIS Gyógyszergyár Rt. | Zpusob prípravy tablet z farmaceuticky aktivních látek majících nevýhodné tabletacní vlastnosti s granulacní kapalinou obsahující mikrokrystalickou celulózu |
WO2005092297A2 (en) * | 2004-03-03 | 2005-10-06 | Teva Pharmaceutical Industries Ltd. | A stable pharmaceutical composition comprising an acid labile drug |
EP1728512A1 (en) * | 2004-03-26 | 2006-12-06 | Eisai R&D Management Co., Ltd. | Controlled-leaching preparation and process for producing the same |
US20090148519A1 (en) * | 2005-09-29 | 2009-06-11 | Yasuhiro Zaima | Pulsed-release preparation having improved disintegration properties in vivo |
-
2005
- 2005-03-23 EP EP05727021A patent/EP1728512A1/en not_active Withdrawn
- 2005-03-23 WO PCT/JP2005/005217 patent/WO2005092336A1/ja active Application Filing
- 2005-03-23 KR KR1020067019778A patent/KR100794078B1/ko not_active IP Right Cessation
- 2005-03-23 RU RU2006134052/15A patent/RU2337687C2/ru not_active IP Right Cessation
- 2005-03-23 MY MYPI20051259A patent/MY139427A/en unknown
- 2005-03-23 NZ NZ549838A patent/NZ549838A/en unknown
- 2005-03-23 CN CNA2005800098028A patent/CN1938026A/zh active Pending
- 2005-03-23 US US10/594,436 patent/US20080095839A1/en not_active Abandoned
- 2005-03-23 AU AU2005225283A patent/AU2005225283B2/en not_active Ceased
- 2005-03-23 CA CA2557791A patent/CA2557791C/en not_active Expired - Fee Related
- 2005-03-23 BR BRPI0509135-7A patent/BRPI0509135A/pt not_active IP Right Cessation
- 2005-03-23 JP JP2006511471A patent/JPWO2005092336A1/ja active Pending
- 2005-03-23 MX MXPA06010785A patent/MXPA06010785A/es active IP Right Grant
- 2005-03-24 TW TW094109169A patent/TW200602085A/zh unknown
-
2006
- 2006-07-25 IL IL177087A patent/IL177087A/en not_active IP Right Cessation
- 2006-09-11 ZA ZA200607603A patent/ZA200607603B/en unknown
- 2006-10-06 US US11/543,991 patent/US20120003311A9/en not_active Abandoned
- 2006-10-26 NO NO20064874A patent/NO20064874L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
RU2006134052A (ru) | 2008-04-10 |
RU2337687C2 (ru) | 2008-11-10 |
MY139427A (en) | 2009-09-30 |
JPWO2005092336A1 (ja) | 2008-02-07 |
CA2557791A1 (en) | 2005-10-06 |
CN1938026A (zh) | 2007-03-28 |
IL177087A (en) | 2011-11-30 |
ZA200607603B (en) | 2007-05-30 |
KR100794078B1 (ko) | 2008-01-10 |
EP1728512A1 (en) | 2006-12-06 |
IL177087A0 (en) | 2006-12-10 |
US20120003311A9 (en) | 2012-01-05 |
NZ549838A (en) | 2010-04-30 |
NO20064874L (no) | 2006-12-19 |
AU2005225283A1 (en) | 2005-10-06 |
US20070110806A1 (en) | 2007-05-17 |
CA2557791C (en) | 2011-03-08 |
KR20060134124A (ko) | 2006-12-27 |
AU2005225283B2 (en) | 2008-09-18 |
MXPA06010785A (es) | 2007-03-28 |
US20080095839A1 (en) | 2008-04-24 |
TW200602085A (en) | 2006-01-16 |
WO2005092336A1 (ja) | 2005-10-06 |
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Legal Events
Date | Code | Title | Description |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
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