CL2008003699A1 - Nanopartícula que comprende pioglitazona y un polímero biocompatible, preparación farmacéutica que la contiene; stent (endoprótesis vascular) que la porta; y su uso en la profilaxis o tratamiento de enfermedades arterioescleróticas. - Google Patents
Nanopartícula que comprende pioglitazona y un polímero biocompatible, preparación farmacéutica que la contiene; stent (endoprótesis vascular) que la porta; y su uso en la profilaxis o tratamiento de enfermedades arterioescleróticas.Info
- Publication number
- CL2008003699A1 CL2008003699A1 CL2008003699A CL2008003699A CL2008003699A1 CL 2008003699 A1 CL2008003699 A1 CL 2008003699A1 CL 2008003699 A CL2008003699 A CL 2008003699A CL 2008003699 A CL2008003699 A CL 2008003699A CL 2008003699 A1 CL2008003699 A1 CL 2008003699A1
- Authority
- CL
- Chile
- Prior art keywords
- nanoparticle
- pioglitazone
- prophylaxis
- treatment
- stent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/422—Anti-atherosclerotic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
Abstract
Nanopartícula que comprende pioglitazona o una sal de la misma y un polímero biocompatible, preparación farmacéutica que comprende la nanopartícula, útil para la producción de un agente farmacéutico para la profilaxis o el tratamiento de enfermedades arterioescleróticas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007322409 | 2007-12-13 | ||
JP2008125071 | 2008-05-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008003699A1 true CL2008003699A1 (es) | 2009-10-09 |
Family
ID=40440298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008003699A CL2008003699A1 (es) | 2007-12-13 | 2008-12-12 | Nanopartícula que comprende pioglitazona y un polímero biocompatible, preparación farmacéutica que la contiene; stent (endoprótesis vascular) que la porta; y su uso en la profilaxis o tratamiento de enfermedades arterioescleróticas. |
Country Status (10)
Country | Link |
---|---|
US (1) | US8337896B2 (es) |
EP (1) | EP2219625B1 (es) |
JP (1) | JP5382879B2 (es) |
CN (1) | CN101969934B (es) |
AR (1) | AR069674A1 (es) |
CL (1) | CL2008003699A1 (es) |
ES (1) | ES2392375T3 (es) |
PE (1) | PE20091265A1 (es) |
TW (1) | TW200932223A (es) |
WO (1) | WO2009075391A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2371370A1 (en) * | 2010-04-01 | 2011-10-05 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Antagonists of miRNA-29 expression and their use in the prevention and treatment of aortic aneurysms and atherosclerotic plaque destabilization |
JP5113958B2 (ja) * | 2010-06-11 | 2013-01-09 | 独立行政法人科学技術振興機構 | 薬剤多量体微粒子及びその製造方法 |
CN101912363A (zh) * | 2010-07-29 | 2010-12-15 | 蔡海德 | 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物 |
WO2012068476A2 (en) | 2010-11-18 | 2012-05-24 | University Of South Florida | Poly(vinyl benzoate) nanoparticles for molecular delivery |
JP2012125180A (ja) * | 2010-12-15 | 2012-07-05 | Kowa Co | 下肢虚血モデル動物 |
US8734898B2 (en) | 2012-09-21 | 2014-05-27 | E I Du Pont De Nemours And Company | Method for producing encapsulated nanoparticles |
CN103006567A (zh) * | 2012-12-21 | 2013-04-03 | 中国海洋大学 | 一种包载亲水性药物的壳聚糖-聚乳酸羟基乙酸复合纳米微粒的制备方法 |
US10232090B2 (en) * | 2013-08-23 | 2019-03-19 | Southwest Research Institute | Electrophoretically deposited strontium fluoride nanoparticle/polymer coatings for medical implants |
WO2015088990A1 (en) | 2013-12-09 | 2015-06-18 | Durect Corporation | Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same |
CN109481419B (zh) * | 2019-01-16 | 2021-04-02 | 中国人民解放军陆军军医大学第一附属医院 | 一种罗格列酮纳米制剂及其制备方法和用途 |
CO2020001235A1 (es) * | 2020-02-03 | 2021-08-09 | Univ Pontificia Bolivariana | Stent |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0740548B1 (en) * | 1994-02-28 | 2002-12-04 | Nanopharm AG | Drug targeting system, method for preparing same and its use |
ATE325607T1 (de) | 1997-11-19 | 2006-06-15 | Takeda Pharmaceutical | Aptoptoseinhibitoren |
ATE372782T1 (de) * | 1999-06-21 | 2007-09-15 | Lilly Co Eli | Synergitische verwendung von thiazolidinedionen und glucagon-ähnlichem peptid-1 und dessen agonisten für die behandlung von nicht-insulin- abhängigen diabetes |
JP2004534721A (ja) * | 2000-10-31 | 2004-11-18 | ピーアール ファーマシューティカルズ,インク. | 生理活性分子の向上した送達のための方法及び組成物 |
EP1382336B1 (en) | 2001-04-25 | 2010-09-08 | Takeda Pharmaceutical Company Limited | Use of the abc expression promotor pioglitazone for the treatment of arteriosclerosis obliterans |
JP2003113120A (ja) * | 2001-08-03 | 2003-04-18 | Takeda Chem Ind Ltd | 徐放性医薬 |
WO2003013609A1 (en) | 2001-08-03 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Sustained-release medicines |
FR2830017B1 (fr) * | 2001-09-27 | 2005-11-04 | Centre Nat Rech Scient | Materiau compose d'au moins un polymere biodegradable et de cyclodextrines |
US20050095267A1 (en) * | 2002-12-04 | 2005-05-05 | Todd Campbell | Nanoparticle-based controlled release polymer coatings for medical implants |
JP4707937B2 (ja) * | 2003-02-28 | 2011-06-22 | ホソカワミクロン株式会社 | 薬物含有複合粒子の製造方法および経肺製剤 |
JP2004267283A (ja) * | 2003-03-05 | 2004-09-30 | Terumo Corp | 体内埋込医療材料および体内埋込医療器具 |
US8119153B2 (en) | 2004-08-26 | 2012-02-21 | Boston Scientific Scimed, Inc. | Stents with drug eluting coatings |
MX2007003789A (es) * | 2004-10-04 | 2007-07-20 | Qlt Usa Inc | Suministro ocular de formulaciones polimericas para suministro. |
US20100221327A1 (en) * | 2005-06-15 | 2010-09-02 | Elan Pharma International Limited | Nanoparticulate azelnidipine formulations |
JP2007119396A (ja) | 2005-10-28 | 2007-05-17 | Hosokawa Funtai Gijutsu Kenkyusho:Kk | 核酸化合物封入ナノ粒子を含む経肺投与用医薬製剤 |
US20070098802A1 (en) * | 2005-10-31 | 2007-05-03 | Isaac Farr | Organic nanoparticles and associated methods |
JP4297221B2 (ja) | 2006-02-15 | 2009-07-15 | 株式会社ホソカワ粉体技術研究所 | 薬剤溶出型ステントの製造方法 |
US20080020014A1 (en) * | 2006-07-19 | 2008-01-24 | Paul Consigny | Implantable devices containing nuclear receptor ligands for the treatment of vascular and related disorders |
US20080026040A1 (en) * | 2006-07-31 | 2008-01-31 | Isaac Farr | Active agent-releasing dosage forms |
US20090074828A1 (en) * | 2007-04-04 | 2009-03-19 | Massachusetts Institute Of Technology | Poly(amino acid) targeting moieties |
-
2008
- 2008-12-12 US US12/735,035 patent/US8337896B2/en not_active Expired - Fee Related
- 2008-12-12 JP JP2010523213A patent/JP5382879B2/ja not_active Expired - Fee Related
- 2008-12-12 CL CL2008003699A patent/CL2008003699A1/es unknown
- 2008-12-12 ES ES08859992T patent/ES2392375T3/es active Active
- 2008-12-12 PE PE2008002062A patent/PE20091265A1/es not_active Application Discontinuation
- 2008-12-12 EP EP08859992A patent/EP2219625B1/en not_active Not-in-force
- 2008-12-12 AR ARP080105407A patent/AR069674A1/es unknown
- 2008-12-12 CN CN2008801267934A patent/CN101969934B/zh not_active Expired - Fee Related
- 2008-12-12 WO PCT/JP2008/073139 patent/WO2009075391A1/en active Application Filing
- 2008-12-12 TW TW097148396A patent/TW200932223A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2009075391A1 (en) | 2009-06-18 |
AR069674A1 (es) | 2010-02-10 |
EP2219625A1 (en) | 2010-08-25 |
CN101969934A (zh) | 2011-02-09 |
JP5382879B2 (ja) | 2014-01-08 |
PE20091265A1 (es) | 2009-09-18 |
EP2219625B1 (en) | 2012-08-01 |
JP2011506268A (ja) | 2011-03-03 |
US8337896B2 (en) | 2012-12-25 |
TW200932223A (en) | 2009-08-01 |
CN101969934B (zh) | 2012-11-21 |
ES2392375T3 (es) | 2012-12-10 |
US20100331373A1 (en) | 2010-12-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2008003699A1 (es) | Nanopartícula que comprende pioglitazona y un polímero biocompatible, preparación farmacéutica que la contiene; stent (endoprótesis vascular) que la porta; y su uso en la profilaxis o tratamiento de enfermedades arterioescleróticas. | |
CY1119582T1 (el) | Υδατικα παρασκευασματα ινσουλινης, που περιεχουν μεθειονινη | |
CY1118661T1 (el) | Φαρμακευτικη συνθεση, φαρμακευτικη δοσολογικη μορφη, διαδικασια για την παρασκευη τους, μεθοδοι για αντιμετωπιση και χρησεις αυτων | |
PH12015500407A1 (en) | Methods of treating hypertriglyceridemia | |
CL2009001077A1 (es) | Vehiculo particulado polimerico que comprende un agente biologico en fase acuosa en un lumen hueco; procedimiento para suministrar una proteina en el ojo; composicion farmaceutica que comprende dicho vehiculo; y su uso para profilaxis y tratar enfermedades o trastornos del ojo. | |
CL2010000188A1 (es) | Metodo para el tratamiento de una infeccion en un sujeto que comprende la administracion de 9-[(2,2-dimetil-propilamino)-metil]-minociclina o de una sal de la misma; composicion farmaceutica que comprende dicho compuesto; y su uso. | |
AR068185A1 (es) | Composiciones de tabletas de desintegracion oral de lamotrigina | |
CY1121865T1 (el) | Οφθαλμολογικες συνθεσεις και η χρηση τους | |
AR050717A1 (es) | Composiciones farmaceuticas | |
CL2008000219A1 (es) | Composicion farmaceutica de liberacion modificada que comprende a uno o mas ingredientes farmaceuticamente activos, con solubilidad dependiente del ph, un polimero controlador de la liberacion, agentes facilitadores de la gelificacion; procedimiento | |
BRPI0917920B8 (pt) | expansão direcional de dispositivos intraluminais | |
CL2011000170A1 (es) | Composicion farmaceutica solida y estabilizada que comprende un ingrediente farmaceuticamente activo, oxido de titanio y un plastificante; procedimiento para estabilizar la composicion farmaceutica durante una irradiacion luminosa. | |
WO2009025926A3 (en) | Nanoparticle-coated medical devices and formulations for treating vascular disease | |
BRPI0607198A2 (pt) | composição, uso da composição método de tratamento doenças, e, embalagem farmacêutica | |
AR053803A1 (es) | Uso de acido pinolenico | |
CL2013001136A1 (es) | Un agente inhibitorio de la fosfodiesterasa 7 (pde7) para ser usado en el tratamiento o la reduccion de la posibilidad de una adiccion; y composicion farmaceutica, forma de dosificacion unitaria y kit farmaceutico que incluyen al inhibidor de fosfodiesterasa 7 (pde7) y un agente terapeutico adicional. | |
BRPI0815577A2 (pt) | Peptídeo foxm1 e agente medicinal compreendendo o mesmo. | |
AR088585A1 (es) | Un medicamento para tratar la enfermedad del ojo anterior | |
CL2013002033A1 (es) | Preparacion oral de desintegracion rapida que comprende granulos que comprenden un medicamento, un agente de desintegracion, un aglutinador, un agente de enmascaramiento y un agente de solubilizacion; metodo de preparacion; su uso para la profilaxis y/o tratamiento de un padecimiento bipolar. | |
WO2006133707A3 (en) | Anti-cancer combination treatment and kit-of-part | |
BRPI0910737A2 (pt) | composto, pró-droga, agente farmacêutico, método para profilaxia ou tratamento de doenças do trato urinário inferior em um mamífero, e, uso de um composto ou uma pró-droga do mesmo. | |
CL2004000899A1 (es) | Composicion farmaceutica que contiene la sal sodica de telmisartan y un agente diuretico y procedimiento de preparacion. | |
AR067420A1 (es) | Combinaciones antitumorales que contienen un agente inhibidor del factor de crecimiento vascular endotelial (vegf) y del irinotecan | |
AR072951A1 (es) | Uso de dronedarona o una sal aceptable farmaceuticamente de esta, para la preparacion de un medicamento para regular el nivel de potasio en la sangre | |
CL2009001841A1 (es) | Uso de una composición de liberación sostenida de 4-aminopiridina para preparar un medicamento útil para tratar esclerosis multiple en un sujeto. |