BRPI0414311A - formas de dosagem de liberação controlada - Google Patents

formas de dosagem de liberação controlada

Info

Publication number
BRPI0414311A
BRPI0414311A BRPI0414311-6A BRPI0414311A BRPI0414311A BR PI0414311 A BRPI0414311 A BR PI0414311A BR PI0414311 A BRPI0414311 A BR PI0414311A BR PI0414311 A BRPI0414311 A BR PI0414311A
Authority
BR
Brazil
Prior art keywords
drug
dosage
formula
release
certain
Prior art date
Application number
BRPI0414311-6A
Other languages
English (en)
Inventor
Anand R Baichwal
Paul Woodcock
Jaclyn Cobb
Raymond Higgins
Original Assignee
Penwest Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US50403503P priority Critical
Application filed by Penwest Pharmaceutical Co filed Critical Penwest Pharmaceutical Co
Priority to PCT/US2004/030450 priority patent/WO2005027878A1/en
Publication of BRPI0414311A publication Critical patent/BRPI0414311A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893Tablet coating processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Abstract

FORMAS DE DOSAGEM DE LIBERAçãO CONTROLADA. A presente invenção se relaciona a uma forma de dosagem para administração oral que preferencialmente libera a droga no o cólon. A presente invenção é adicionalmentemente relacionada a métodos de preparar tais formulações, e métodos de tratamento utilizando tais formulações. é um objeto da presente invenção prover uma fórmula de dosagem farmacêutica oral que formar que preveja o atraso da liberação da(s) droga(s) no cólon de um ser humano depois de ingestão oral da fórmula dosada. é um objeto adicionalmentemente de certas incorporações da presente invenção prover uma fórmula de dosagem farmacêutica oral que provê um atraso para liberar demora liberar uma(s) droga(s) na área gastrintestinal de um ser humano como isso a droga é liberada no cólon. é um objeto adicionalmentemente de certas incorporações da presente invenção para prover uma fórmula de dosagem farmacêutica tendo um núcleo contendo droga, o núcleo sendo comprimido e coberto com uma coberta com uma camada que provê um atraso para liberar a fórmula de dosagem depois da dosagem ser oralmente administrada para um ser humano. é um objeto adicionalmentemente de certas incorporações da presente invenção para prover uma fórmula de dosagem farmacêutica oral tendo uma droga contenda um núcleo que é comprimida e coberta com uma camada que provê um atraso para liberar a droga quando a fórmula de dosagem for oralmente administrado em um ser humano. é um objeto adicionalmentemente de certas incorporações da presente invenção para prover uma fórmula que permite a dosagem para especificamente o cólon atuando para uma larga variedade de doenças. é um objeto adicionalmentemente de certas Incorporações da presente invenção para prover dosagem forma atuando em doenças como colite ulcerativa, Doença do Crohn ou outras doenças que são tipicamente mais sintomáticas em área gastrintestinal inferior. é um objeto adicionalmentemente de certas incorporações da presente invenção para prover uma fórmula de dosagem que prevê um atraso para liberar a droga da fórmula de dosagem tal que a droga é liberada no cólon, seguido por um liberação controlada da droga depois disso. é um objeto adicionalmentemente de certas incorporações da presente invenção prover uma compressão da cobertura da fórmula de dosagem tendo uma imediata liberação da camada de uma(s) droga(s) com uma sobre cobertura sobre o núcleo comprimido que prevê um atraso para liberar a mesma droga ou diferente(s) da fórmula de dosagem; o núcleo opcionalmente provendo um liberação controlada da droga depois disso. é um objeto adicionalmentemente de certas incorporações da presente invenção prover uma fórmula de dosagem oral que provê um local de liberação específico de droga (P,.ex., para o cólon). é um objeto adicionalmentemente de certas incorporações da presente invenção para desenvolver uma fórmula de dosagem oral que prevê liberação programada da droga. é um objeto adicionalmentemente de certas incorporações da presente invenção para desenvolver uma fórmula de dosagem oral que prevê a liberação pulsativa da droga.
BRPI0414311-6A 2003-09-19 2004-09-17 formas de dosagem de liberação controlada BRPI0414311A (pt)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US50403503P true 2003-09-19 2003-09-19
PCT/US2004/030450 WO2005027878A1 (en) 2003-09-19 2004-09-17 Delayed released dosage forms

Publications (1)

Publication Number Publication Date
BRPI0414311A true BRPI0414311A (pt) 2008-03-04

Family

ID=34375438

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414311-6A BRPI0414311A (pt) 2003-09-19 2004-09-17 formas de dosagem de liberação controlada

Country Status (13)

Country Link
US (1) US8389008B2 (pt)
EP (1) EP1670442A4 (pt)
JP (1) JP2007505921A (pt)
KR (1) KR100782918B1 (pt)
CN (1) CN1882316A (pt)
AP (1) AP200603585A0 (pt)
BR (1) BRPI0414311A (pt)
CA (1) CA2539051C (pt)
EA (1) EA200600598A1 (pt)
IL (1) IL174343D0 (pt)
MX (1) MXPA06003100A (pt)
NZ (1) NZ545921A (pt)
WO (1) WO2005027878A1 (pt)

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CA2539051A1 (en) 2005-03-31
IL174343D0 (en) 2009-02-11
EP1670442A1 (en) 2006-06-21
AU2004273956A1 (en) 2005-03-31
EA200600598A1 (ru) 2006-08-25
CA2539051C (en) 2014-08-12
KR20060070565A (ko) 2006-06-23
CN1882316A (zh) 2006-12-20
WO2005027878A1 (en) 2005-03-31
KR100782918B1 (ko) 2007-12-07
US20050112201A1 (en) 2005-05-26
EP1670442A4 (en) 2011-09-14
AP200603585A0 (en) 2006-04-30
US8389008B2 (en) 2013-03-05
MXPA06003100A (es) 2006-06-20

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