ATE143368T1 - Wasserlösliche camptothecin-analoge - Google Patents

Wasserlösliche camptothecin-analoge

Info

Publication number
ATE143368T1
ATE143368T1 AT88311366T AT88311366T ATE143368T1 AT E143368 T1 ATE143368 T1 AT E143368T1 AT 88311366 T AT88311366 T AT 88311366T AT 88311366 T AT88311366 T AT 88311366T AT E143368 T1 ATE143368 T1 AT E143368T1
Authority
AT
Austria
Prior art keywords
alkyl
hydrogen
water soluble
ch2nh2
formyl
Prior art date
Application number
AT88311366T
Other languages
English (en)
Inventor
Jeffrey Charles Boehm
Randall Keith Johnson
Sidney Michael Hecht
William Dennis Kingsbury
Kenneth George Holden
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE143368T1 publication Critical patent/ATE143368T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Semiconductor Lasers (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT88311366T 1987-12-01 1988-11-30 Wasserlösliche camptothecin-analoge ATE143368T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12714887A 1987-12-01 1987-12-01

Publications (1)

Publication Number Publication Date
ATE143368T1 true ATE143368T1 (de) 1996-10-15

Family

ID=22428545

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88311366T ATE143368T1 (de) 1987-12-01 1988-11-30 Wasserlösliche camptothecin-analoge

Country Status (25)

Country Link
US (1) US5004758A (de)
EP (1) EP0321122B1 (de)
JP (1) JPH0633268B2 (de)
KR (1) KR930009357B1 (de)
CN (3) CN1027265C (de)
AT (1) ATE143368T1 (de)
AU (1) AU612735B2 (de)
CA (1) CA1308102C (de)
CY (1) CY2017A (de)
DE (2) DE19775017I2 (de)
DK (1) DK173034B1 (de)
ES (1) ES2094721T3 (de)
FI (1) FI89923C (de)
GR (1) GR3021990T3 (de)
HK (1) HK81097A (de)
IE (1) IE74873B1 (de)
IL (1) IL88517A (de)
LU (2) LU90026I2 (de)
MX (1) MX9203744A (de)
NL (1) NL970017I2 (de)
NO (2) NO170487C (de)
NZ (1) NZ227124A (de)
PT (1) PT89111B (de)
SG (1) SG66254A1 (de)
ZA (1) ZA888938B (de)

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EP0321122A3 (de) 1990-12-27
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EP0321122B1 (de) 1996-09-25
FI89923C (fi) 1993-12-10
FI885569A (fi) 1989-06-02
FI89923B (fi) 1993-08-31
IL88517A0 (en) 1989-06-30
LU90053I2 (fr) 1997-07-01
AU612735B2 (en) 1991-07-18
NO885352L (no) 1989-06-02
KR890009934A (ko) 1989-08-05
DK663688A (da) 1989-06-02
NO170487B (no) 1992-07-13
DK663688D0 (da) 1988-11-28
NO170487C (no) 1992-10-21
CY2017A (en) 1998-02-20
KR930009357B1 (ko) 1993-09-28
PT89111A (pt) 1989-12-29
NO885352D0 (no) 1988-11-30
DE19775017I2 (de) 2002-11-07
JPH0633268B2 (ja) 1994-05-02
CN1037574C (zh) 1998-03-04
EP0321122A2 (de) 1989-06-21
PT89111B (pt) 1994-01-31
US5004758A (en) 1991-04-02
NL970017I2 (nl) 1997-09-01
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CN1035380C (zh) 1997-07-09
GR3021990T3 (en) 1997-03-31
CN1034724A (zh) 1989-08-16
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DE3855575D1 (de) 1996-10-31
LU90026I2 (fr) 1997-04-22
IL88517A (en) 1994-10-07
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CN1083817A (zh) 1994-03-16
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ES2094721T3 (es) 1997-02-01
CA1308102C (en) 1992-09-29
IE883576L (en) 1989-06-01
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ZA888938B (en) 1990-03-28
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