DK663688A - Vandoploeselige camptothecinanaloger, fremgangsmaade til fremstilling deraf samt midler indeholdende disse - Google Patents

Vandoploeselige camptothecinanaloger, fremgangsmaade til fremstilling deraf samt midler indeholdende disse

Info

Publication number
DK663688A
DK663688A DK663688A DK663688A DK663688A DK 663688 A DK663688 A DK 663688A DK 663688 A DK663688 A DK 663688A DK 663688 A DK663688 A DK 663688A DK 663688 A DK663688 A DK 663688A
Authority
DK
Denmark
Prior art keywords
alkyl
hydrogen
procedures
preparing
water soluble
Prior art date
Application number
DK663688A
Other languages
English (en)
Other versions
DK663688D0 (da
DK173034B1 (da
Inventor
Jeffrey Charles Boehm
Sidney Michael Hecht
Kenneth George Holden
Randall Keith Johnson
William Dennis Kingsbury
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK663688D0 publication Critical patent/DK663688D0/da
Publication of DK663688A publication Critical patent/DK663688A/da
Application granted granted Critical
Publication of DK173034B1 publication Critical patent/DK173034B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Semiconductor Lasers (AREA)
DK198806636A 1987-12-01 1988-11-28 Vandopløselige S-isomerer og racemiske blandinger af camptothecinanaloger, fremgangsmåde til fremstilling deraf samt midler DK173034B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12714887A 1987-12-01 1987-12-01
US12714887 1987-12-01

Publications (3)

Publication Number Publication Date
DK663688D0 DK663688D0 (da) 1988-11-28
DK663688A true DK663688A (da) 1989-06-02
DK173034B1 DK173034B1 (da) 1999-11-29

Family

ID=22428545

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198806636A DK173034B1 (da) 1987-12-01 1988-11-28 Vandopløselige S-isomerer og racemiske blandinger af camptothecinanaloger, fremgangsmåde til fremstilling deraf samt midler

Country Status (25)

Country Link
US (1) US5004758A (da)
EP (1) EP0321122B1 (da)
JP (1) JPH0633268B2 (da)
KR (1) KR930009357B1 (da)
CN (3) CN1027265C (da)
AT (1) ATE143368T1 (da)
AU (1) AU612735B2 (da)
CA (1) CA1308102C (da)
CY (1) CY2017A (da)
DE (2) DE19775017I2 (da)
DK (1) DK173034B1 (da)
ES (1) ES2094721T3 (da)
FI (1) FI89923C (da)
GR (1) GR3021990T3 (da)
HK (1) HK81097A (da)
IE (1) IE74873B1 (da)
IL (1) IL88517A (da)
LU (2) LU90026I2 (da)
MX (1) MX9203744A (da)
NL (1) NL970017I2 (da)
NO (2) NO170487C (da)
NZ (1) NZ227124A (da)
PT (1) PT89111B (da)
SG (1) SG66254A1 (da)
ZA (1) ZA888938B (da)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
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CN1027265C (zh) 1995-01-04
CN1083817A (zh) 1994-03-16
CN1034724A (zh) 1989-08-16
CA1308102C (en) 1992-09-29
NO1998003I1 (no) 1998-01-15
ATE143368T1 (de) 1996-10-15
NO885352L (no) 1989-06-02
NO885352D0 (no) 1988-11-30
PT89111B (pt) 1994-01-31
LU90053I2 (fr) 1997-07-01
NZ227124A (en) 1991-12-23
DK663688D0 (da) 1988-11-28
MX9203744A (es) 1992-09-01
FI89923B (fi) 1993-08-31
IE74873B1 (en) 1997-08-13
LU90026I2 (fr) 1997-04-22
CN1035380C (zh) 1997-07-09
ZA888938B (en) 1990-03-28
ES2094721T3 (es) 1997-02-01
DE3855575D1 (de) 1996-10-31
CY2017A (en) 1998-02-20
SG66254A1 (en) 1999-07-20
FI885569A0 (fi) 1988-11-30
EP0321122A2 (en) 1989-06-21
KR890009934A (ko) 1989-08-05
FI89923C (fi) 1993-12-10
CN1087637A (zh) 1994-06-08
IL88517A0 (en) 1989-06-30
IE883576L (en) 1989-06-01
DK173034B1 (da) 1999-11-29
FI885569A (fi) 1989-06-02
US5004758A (en) 1991-04-02
IL88517A (en) 1994-10-07
PT89111A (pt) 1989-12-29
EP0321122A3 (en) 1990-12-27
DE3855575T2 (de) 1997-03-20
NL970017I2 (nl) 1997-09-01
KR930009357B1 (ko) 1993-09-28
NO170487C (no) 1992-10-21
JPH01186893A (ja) 1989-07-26
AU612735B2 (en) 1991-07-18
CN1037574C (zh) 1998-03-04
GR3021990T3 (en) 1997-03-31
EP0321122B1 (en) 1996-09-25
HK81097A (en) 1997-06-20
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DE19775017I2 (de) 2002-11-07
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AU2639488A (en) 1989-06-01
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Filing date: 20000518

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