AR045056A1 - Anticuerpos anti-ngf humanos neutralizantes como inhibidores selectivos de la via de ngf - Google Patents

Anticuerpos anti-ngf humanos neutralizantes como inhibidores selectivos de la via de ngf

Info

Publication number
AR045056A1
AR045056A1 ARP040102501A ARP040102501A AR045056A1 AR 045056 A1 AR045056 A1 AR 045056A1 AR P040102501 A ARP040102501 A AR P040102501A AR P040102501 A ARP040102501 A AR P040102501A AR 045056 A1 AR045056 A1 AR 045056A1
Authority
AR
Argentina
Prior art keywords
ngf
antibody
variable region
specifically binds
heavy chain
Prior art date
Application number
ARP040102501A
Other languages
English (en)
Spanish (es)
Inventor
Kenneth D Wild Jr
James J S Treanor
Haichun Huang
Heather Inoue
Tie J Zhang
Frank Martin
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of AR045056A1 publication Critical patent/AR045056A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/567—Framework region [FR]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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ARP040102501A 2003-07-15 2004-07-15 Anticuerpos anti-ngf humanos neutralizantes como inhibidores selectivos de la via de ngf AR045056A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48743103P 2003-07-15 2003-07-15

Publications (1)

Publication Number Publication Date
AR045056A1 true AR045056A1 (es) 2005-10-12

Family

ID=34215825

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP040102501A AR045056A1 (es) 2003-07-15 2004-07-15 Anticuerpos anti-ngf humanos neutralizantes como inhibidores selectivos de la via de ngf
ARP100100652A AR075790A2 (es) 2003-07-15 2010-03-04 Anticuerpos anti -ngf humanos neutralizantes como inhibidores selectivos de la via de ngf (factor de crecimiento neural)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP100100652A AR075790A2 (es) 2003-07-15 2010-03-04 Anticuerpos anti -ngf humanos neutralizantes como inhibidores selectivos de la via de ngf (factor de crecimiento neural)

Country Status (30)

Country Link
US (7) US7601818B2 (https=)
EP (2) EP2364728A1 (https=)
JP (8) JP4489077B2 (https=)
CN (3) CN102408483B (https=)
AR (2) AR045056A1 (https=)
AU (2) AU2004267030B2 (https=)
BR (1) BRPI0412567B1 (https=)
CA (1) CA2534585C (https=)
CY (1) CY1113167T1 (https=)
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