JP2004501631A5 - - Google Patents

Info

Publication number

JP2004501631A5

JP2004501631A5 JP2002505852A JP2002505852A JP2004501631A5 JP 2004501631 A5 JP2004501631 A5 JP 2004501631A5 JP 2002505852 A JP2002505852 A JP 2002505852A JP 2002505852 A JP2002505852 A JP 2002505852A JP 2004501631 A5 JP2004501631 A5 JP 2004501631A5

Authority

JP

Japan

Prior art keywords

nucleic acid

seq

amino acid

acid molecule

fragment

Prior art date

2001-06-28

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 102000039446 nucleic acids Human genes 0.000 description 63
• 108020004707 nucleic acids Proteins 0.000 description 63
• 150000007523 nucleic acids Chemical class 0.000 description 63
• 239000002773 nucleotide Substances 0.000 description 54
• 125000003729 nucleotide group Chemical group 0.000 description 54
• 239000012634 fragment Substances 0.000 description 38
• 108700030875 Programmed Cell Death 1 Ligand 2 Proteins 0.000 description 36
• 125000003275 alpha amino acid group Chemical group 0.000 description 36
• 101100407308 Mus musculus Pdcd1lg2 gene Proteins 0.000 description 31
• 102100024213 Programmed cell death 1 ligand 2 Human genes 0.000 description 31
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 27
• 229920001184 polypeptide Polymers 0.000 description 18
• 108090000765 processed proteins & peptides Proteins 0.000 description 18
• 102000004196 processed proteins & peptides Human genes 0.000 description 18
• 239000003814 drug Substances 0.000 description 15
• 230000028993 immune response Effects 0.000 description 14
• 238000000034 method Methods 0.000 description 11
• 125000000539 amino acid group Chemical group 0.000 description 9
• 230000000694 effects Effects 0.000 description 8
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• 150000001875 compounds Chemical class 0.000 description 6
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• 108010074708 B7-H1 Antigen Proteins 0.000 description 2
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• 102100024216 Programmed cell death 1 ligand 1 Human genes 0.000 description 2
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• 102000016266 T-Cell Antigen Receptors Human genes 0.000 description 1
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