JP2022542443A5 - - Google Patents
Info
- Publication number
- JP2022542443A5 JP2022542443A5 JP2022506455A JP2022506455A JP2022542443A5 JP 2022542443 A5 JP2022542443 A5 JP 2022542443A5 JP 2022506455 A JP2022506455 A JP 2022506455A JP 2022506455 A JP2022506455 A JP 2022506455A JP 2022542443 A5 JP2022542443 A5 JP 2022542443A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- seq
- bcma
- amino acid
- antigen receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19382673.2 | 2019-08-02 | ||
| EP19382673 | 2019-08-02 | ||
| PCT/EP2020/071831 WO2021023721A1 (en) | 2019-08-02 | 2020-08-03 | Car t-cells against bcma for the treatment of multiple myeloma |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022542443A JP2022542443A (ja) | 2022-10-03 |
| JP2022542443A5 true JP2022542443A5 (https=) | 2023-08-14 |
| JP7729561B2 JP7729561B2 (ja) | 2025-08-26 |
Family
ID=67658496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506455A Active JP7729561B2 (ja) | 2019-08-02 | 2020-08-03 | 多発性骨髄腫治療用の抗ｂｃｍａ ｃａｒ ｔ細胞 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US12509525B2 (https=) |
| EP (2) | EP4272837A3 (https=) |
| JP (1) | JP7729561B2 (https=) |
| AU (1) | AU2020325690A1 (https=) |
| CA (1) | CA3148930A1 (https=) |
| DK (1) | DK4007777T5 (https=) |
| ES (1) | ES2971033T3 (https=) |
| FI (1) | FI4007777T3 (https=) |
| HR (1) | HRP20240037T1 (https=) |
| HU (1) | HUE064890T2 (https=) |
| LT (1) | LT4007777T (https=) |
| PL (1) | PL4007777T3 (https=) |
| PT (1) | PT4007777T (https=) |
| RS (1) | RS65094B1 (https=) |
| SI (1) | SI4007777T1 (https=) |
| SM (1) | SMT202400013T1 (https=) |
| WO (1) | WO2021023721A1 (https=) |
| ZA (1) | ZA202201166B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250021397A (ko) * | 2022-02-09 | 2025-02-12 | 하다지트 메디칼 리서치 써비시즈 앤드 디벨롭먼트 리미티드 | 면역 관련 질환을 표적으로 하는 항-bcma car, 조성물 및 이의 방법 |
| EP4378953A1 (en) * | 2022-12-02 | 2024-06-05 | Universitat de Barcelona | Cd229 targeting moiety for the tratment of cd229 positive cancer |
| WO2025141187A1 (en) * | 2023-12-29 | 2025-07-03 | Fundación Para La Investigación Biomédica Del Hospital Universitario 12 De Octubre | T cells expressing anti-bcma/anti-cd3 bispecific antibodies and uses thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0436597B1 (en) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| CA2095633C (en) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Enrichment method for variant proteins with altered binding properties |
| EP1820858B1 (en) | 1991-03-01 | 2009-08-12 | Dyax Corporation | Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof |
| ATE414768T1 (de) | 1991-04-10 | 2008-12-15 | Scripps Research Inst | Bibliotheken heterodimerer rezeptoren mittels phagemiden |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| US5674704A (en) | 1993-05-07 | 1997-10-07 | Immunex Corporation | Cytokine designated 4-IBB ligand |
| NO3051026T3 (https=) | 2011-10-21 | 2018-07-28 | ||
| WO2014068079A1 (en) | 2012-11-01 | 2014-05-08 | Max-Delbrück-Centrum für Molekulare Medizin | An antibody that binds cd269 (bcma) suitable for use in the treatment of plasma cell diseases such as multiple myeloma and autoimmune diseases |
| ES2546743B1 (es) | 2014-03-28 | 2016-07-07 | Institut D'investigació Biomèdica De Bellvitge (Idibell) | Marcadores mitocondriales de enfermedades neurodegenerativas |
| KR102526945B1 (ko) | 2014-04-30 | 2023-04-27 | 막스-델부뤽-센트럼 퓌어 몰레쿨라레 메디친 인 데어 헬름홀츠-게마인샤프트 | Ｃｄ269에 대한 인간화 항체 |
| KR20170066546A (ko) | 2014-10-03 | 2017-06-14 | 노파르티스 아게 | 조합 요법 |
| SG10202012157QA (en) | 2016-06-07 | 2021-01-28 | Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft | Chimeric antigen receptor and car-t cells that bind bcma |
| CN108004259B (zh) * | 2016-11-02 | 2020-06-30 | 上海恒润达生生物科技有限公司 | 靶向b细胞成熟抗原的嵌合抗原受体及其用途 |
| CN108285489A (zh) * | 2017-01-09 | 2018-07-17 | 上海恒润达生生物科技有限公司 | 靶向BCMA-BBz-tEGFR的嵌合抗原受体及其用途 |
| CN108395478A (zh) | 2017-02-04 | 2018-08-14 | 上海恒润达生生物科技有限公司 | 靶向bcma的嵌合抗原受体并对其双重修饰的方法及其用途 |
| MX2019013514A (es) * | 2017-05-12 | 2020-01-20 | Crispr Therapeutics Ag | Materiales y metodos para modificar celulas por ingenieria genetica y usos de los mismos en inmunooncologia. |
| ES2953362T3 (es) | 2018-03-13 | 2023-11-10 | Sepsia Therapeutics S L | Péptidos de unión bacteriana para el tratamiento de enfermedades infecciosas y procesos inflamatorios relacionados |
-
2020
- 2020-08-03 AU AU2020325690A patent/AU2020325690A1/en active Pending
- 2020-08-03 CA CA3148930A patent/CA3148930A1/en active Pending
- 2020-08-03 US US17/632,191 patent/US12509525B2/en active Active
- 2020-08-03 LT LTEPPCT/EP2020/071831T patent/LT4007777T/lt unknown
- 2020-08-03 HR HRP20240037TT patent/HRP20240037T1/hr unknown
- 2020-08-03 JP JP2022506455A patent/JP7729561B2/ja active Active
- 2020-08-03 ES ES20757544T patent/ES2971033T3/es active Active
- 2020-08-03 EP EP23190869.0A patent/EP4272837A3/en active Pending
- 2020-08-03 WO PCT/EP2020/071831 patent/WO2021023721A1/en not_active Ceased
- 2020-08-03 PT PT207575440T patent/PT4007777T/pt unknown
- 2020-08-03 SI SI202030350T patent/SI4007777T1/sl unknown
- 2020-08-03 PL PL20757544.0T patent/PL4007777T3/pl unknown
- 2020-08-03 FI FIEP20757544.0T patent/FI4007777T3/fi active
- 2020-08-03 EP EP20757544.0A patent/EP4007777B1/en active Active
- 2020-08-03 SM SM20240013T patent/SMT202400013T1/it unknown
- 2020-08-03 HU HUE20757544A patent/HUE064890T2/hu unknown
- 2020-08-03 DK DK20757544.0T patent/DK4007777T5/da active
- 2020-08-03 RS RS20240043A patent/RS65094B1/sr unknown
-
2022
- 2022-01-25 ZA ZA2022/01166A patent/ZA202201166B/en unknown
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