JP2022512882A5 - - Google Patents
Info
- Publication number
- JP2022512882A5 JP2022512882A5 JP2021523715A JP2021523715A JP2022512882A5 JP 2022512882 A5 JP2022512882 A5 JP 2022512882A5 JP 2021523715 A JP2021523715 A JP 2021523715A JP 2021523715 A JP2021523715 A JP 2021523715A JP 2022512882 A5 JP2022512882 A5 JP 2022512882A5
- Authority
- JP
- Japan
- Prior art keywords
- manipulated
- population
- cells
- sequence
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862756718P | 2018-11-07 | 2018-11-07 | |
| US62/756,718 | 2018-11-07 | ||
| US201862767388P | 2018-11-14 | 2018-11-14 | |
| US201862767395P | 2018-11-14 | 2018-11-14 | |
| US62/767,388 | 2018-11-14 | ||
| US62/767,395 | 2018-11-14 | ||
| US201962826643P | 2019-03-29 | 2019-03-29 | |
| US201962826648P | 2019-03-29 | 2019-03-29 | |
| US62/826,648 | 2019-03-29 | ||
| US62/826,643 | 2019-03-29 | ||
| PCT/IB2019/001194 WO2020095107A1 (en) | 2018-11-07 | 2019-11-07 | Anti-cd33 immune cell cancer therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022512882A JP2022512882A (ja) | 2022-02-07 |
| JP2022512882A5 true JP2022512882A5 (https=) | 2022-11-15 |
| JP7553440B2 JP7553440B2 (ja) | 2024-09-18 |
Family
ID=69159803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021523715A Active JP7553440B2 (ja) | 2018-11-07 | 2019-11-07 | 抗cd33免疫細胞癌療法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220226375A1 (https=) |
| EP (1) | EP3877414A1 (https=) |
| JP (1) | JP7553440B2 (https=) |
| KR (1) | KR20210089712A (https=) |
| CN (1) | CN113227141A (https=) |
| AU (1) | AU2019377892A1 (https=) |
| BR (1) | BR112021008041A2 (https=) |
| CA (1) | CA3118816A1 (https=) |
| IL (1) | IL282286A (https=) |
| MX (1) | MX2021005398A (https=) |
| SG (1) | SG11202103832SA (https=) |
| WO (1) | WO2020095107A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2019130504A (ru) | 2017-02-28 | 2021-03-30 | Вор Байофарма, Инк. | Композиции и способы ингибирования линиеспецифических белков |
| EA202092044A1 (ru) * | 2018-03-14 | 2021-03-03 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Химерные рецепторы антигена против cd33 и их применения |
| CA3110837A1 (en) | 2018-08-28 | 2020-03-05 | Vor Biopharma Inc. | Genetically engineered hematopoietic stem cells and uses thereof |
| AU2020280103A1 (en) * | 2019-05-23 | 2021-12-23 | Vor Biopharma Inc. | Compositions and methods for CD33 modification |
| WO2020261219A1 (en) | 2019-06-27 | 2020-12-30 | Crispr Therapeutics Ag | Use of chimeric antigen receptor t cells and nk cell inhibitors for treating cancer |
| KR20220051401A (ko) | 2019-09-06 | 2022-04-26 | 크리스퍼 테라퓨틱스 아게 | 배양 중 개선된 지속성을 갖는 유전적으로 조작된 t 세포 |
| CN116322716A (zh) | 2020-09-23 | 2023-06-23 | 克里斯珀医疗股份公司 | Regnase-1和/或TGFBRII被破坏的基因工程化T细胞具有改善的功能性和持久性 |
| MX2023004811A (es) * | 2020-10-26 | 2023-06-29 | Res Institute At Nationwide Children´S Hospital | Células nk del receptor de antígeno quimérico (car) y usos de las mismas. |
| WO2022137181A1 (en) | 2020-12-23 | 2022-06-30 | Crispr Therapeutics Ag | Co-use of lenalidomide with car-t cells |
| EP4305153A1 (en) | 2021-03-09 | 2024-01-17 | CRISPR Therapeutics AG | Genetically engineered t cells with ptpn2 knockout have improved functionality and anti-tumor activity |
| US20230346836A1 (en) | 2021-12-22 | 2023-11-02 | Crispr Therapeutics Ag | Genetically engineered t cells with disrupted casitas b-lineage lymphoma proto-oncogene-b (cblb) and uses thereof |
| WO2024023801A2 (en) | 2022-07-29 | 2024-02-01 | Crispr Therapeutics Ag | Genetically engineered immune cells having disrupted transporter associated with antigen processing-1 (tap-1) gene |
| WO2024023802A2 (en) | 2022-07-29 | 2024-02-01 | Crispr Therapeutics Ag | Genetically engineered immune cells having disrupted transporter associated with antigen processing-2 (tap-2) gene |
| WO2024023804A2 (en) | 2022-07-29 | 2024-02-01 | Crispr Therapeutics Ag | Genetically engineered immune cells having disrupted transporter associated with antigen processing binding protein (tapbp) gene |
| WO2024192108A1 (en) | 2023-03-14 | 2024-09-19 | Evolveimmune Therapeutics, Inc. | Genetically modified car t cells and methods of making and using the same |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US5858358A (en) | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
| US7175843B2 (en) | 1994-06-03 | 2007-02-13 | Genetics Institute, Llc | Methods for selectively stimulating proliferation of T cells |
| US5773001A (en) | 1994-06-03 | 1998-06-30 | American Cyanamid Company | Conjugates of methyltrithio antitumor agents and intermediates for their synthesis |
| US7067318B2 (en) | 1995-06-07 | 2006-06-27 | The Regents Of The University Of Michigan | Methods for transfecting T cells |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| KR20030032922A (ko) | 2000-02-24 | 2003-04-26 | 싸이트 테라피스 인코포레이티드 | 세포의 동시 자극 및 농축 |
| JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
| JP2005500061A (ja) | 2001-08-20 | 2005-01-06 | ザ スクリップス リサーチ インスティテュート | Cnnについての亜鉛フィンガー結合ドメイン |
| ZA200503075B (en) * | 2002-11-07 | 2006-09-27 | Immunogen Inc | Anti-CD33 antibodies and method for treatment of acute myeloid leukemia using the same |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| WO2011072246A2 (en) | 2009-12-10 | 2011-06-16 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
| WO2013026839A1 (en) * | 2011-08-23 | 2013-02-28 | Roche Glycart Ag | Bispecific antibodies specific for t-cell activating antigens and a tumor antigen and methods of use |
| WO2013026837A1 (en) * | 2011-08-23 | 2013-02-28 | Roche Glycart Ag | Bispecific t cell activating antigen binding molecules |
| US20130309223A1 (en) * | 2012-05-18 | 2013-11-21 | Seattle Genetics, Inc. | CD33 Antibodies And Use Of Same To Treat Cancer |
| EP2961773B1 (en) | 2013-02-26 | 2019-03-20 | Roche Glycart AG | Bispecific t cell activating antigen binding molecules |
| AU2014248640B2 (en) | 2013-03-13 | 2018-03-01 | Seagen Inc. | Cyclodextrin and antibody-drug conjugate formulations |
| JP6681837B2 (ja) * | 2014-03-11 | 2020-04-15 | セレクティスCellectis | 同種移植に適合するt細胞を作製するための方法 |
| CN106795221B (zh) * | 2014-04-03 | 2022-06-07 | 塞勒克提斯公司 | 用于癌症免疫治疗的cd33特异性嵌合抗原受体 |
| TWI719942B (zh) * | 2014-07-21 | 2021-03-01 | 瑞士商諾華公司 | 使用cd33嵌合抗原受體治療癌症 |
| US20170335331A1 (en) | 2014-10-31 | 2017-11-23 | The Trustees Of The University Of Pennsylvania | Altering Gene Expression in CART Cells and Uses Thereof |
| JP2018509148A (ja) * | 2015-03-11 | 2018-04-05 | セレクティスCellectis | 患者における持続性および/または生着を増加させるために同種t細胞を改変する方法 |
| WO2017025323A1 (en) * | 2015-08-11 | 2017-02-16 | Cellectis | Cells for immunotherapy engineered for targeting cd38 antigen and for cd38 gene inactivation |
| AU2016337525B2 (en) | 2015-10-16 | 2022-01-20 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for inhibition of lineage specific antigens |
| WO2018073393A2 (en) * | 2016-10-19 | 2018-04-26 | Cellectis | Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy |
| EP3548055A4 (en) * | 2016-12-02 | 2020-08-19 | University of Southern California | SYNTHETIC IMMUNE RECEPTORS AND THEIR PROCESSES FOR USE |
| SG11201907638QA (en) | 2017-02-20 | 2019-09-27 | Dragonfly Therapeutics Inc | Proteins binding cd33, nkg2d and cd16 |
| CN107746831B (zh) | 2017-11-07 | 2019-04-23 | 南京北恒生物科技有限公司 | 具有化疗药物抗性的通用型cart/tcrt细胞及其构建方法 |
-
2019
- 2019-11-07 BR BR112021008041-4A patent/BR112021008041A2/pt not_active Application Discontinuation
- 2019-11-07 KR KR1020217017175A patent/KR20210089712A/ko not_active Withdrawn
- 2019-11-07 US US17/291,181 patent/US20220226375A1/en active Pending
- 2019-11-07 CN CN201980072322.8A patent/CN113227141A/zh active Pending
- 2019-11-07 SG SG11202103832SA patent/SG11202103832SA/en unknown
- 2019-11-07 EP EP19835713.9A patent/EP3877414A1/en active Pending
- 2019-11-07 JP JP2021523715A patent/JP7553440B2/ja active Active
- 2019-11-07 MX MX2021005398A patent/MX2021005398A/es unknown
- 2019-11-07 AU AU2019377892A patent/AU2019377892A1/en not_active Withdrawn
- 2019-11-07 WO PCT/IB2019/001194 patent/WO2020095107A1/en not_active Ceased
- 2019-11-07 CA CA3118816A patent/CA3118816A1/en active Pending
-
2021
- 2021-04-13 IL IL282286A patent/IL282286A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022512882A5 (https=) | ||
| JP2021522820A5 (https=) | ||
| JP2022513586A5 (https=) | ||
| CN114585645B (zh) | 对杂合性丧失作出响应的细胞表面受体 | |
| CN107709548B (zh) | 用于增强治疗性免疫细胞的功效的方法 | |
| CN112390892B (zh) | 一种嵌合抗原受体以及表达该嵌抗原受体的免疫效应细胞 | |
| JP2021531004A5 (https=) | ||
| JP2022509017A5 (https=) | ||
| JP2023542348A5 (https=) | ||
| JP2016514462A5 (https=) | ||
| JP2021525524A5 (https=) | ||
| KR102859548B1 (ko) | 메소텔린 양성 암을 치료하기 위한 조성물 및 방법 | |
| JP2018508215A5 (https=) | ||
| JP2021503006A5 (https=) | ||
| JP2018536436A5 (https=) | ||
| US20170081411A1 (en) | Regulatable chimeric antigen receptor | |
| JP2023514407A5 (https=) | ||
| JP2017500869A5 (https=) | ||
| KR102859550B1 (ko) | Ceacam 양성 암을 치료하기 위한 조성물 및 방법 | |
| AU2016382512A1 (en) | Immune effector cell therapies with enhanced efficacy | |
| CN107735407A (zh) | 治疗剂 | |
| JP2024097924A (ja) | 抗ptk7免疫細胞癌療法 | |
| CN115916833B (zh) | 靶向b7h3的抗原结合多肽及其应用 | |
| CN107106670A (zh) | 用于修饰的t细胞的方法和组合物 | |
| JP2024097924A5 (https=) |