JP2023542348A5 - - Google Patents
Info
- Publication number
- JP2023542348A5 JP2023542348A5 JP2023518205A JP2023518205A JP2023542348A5 JP 2023542348 A5 JP2023542348 A5 JP 2023542348A5 JP 2023518205 A JP2023518205 A JP 2023518205A JP 2023518205 A JP2023518205 A JP 2023518205A JP 2023542348 A5 JP2023542348 A5 JP 2023542348A5
- Authority
- JP
- Japan
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063082357P | 2020-09-23 | 2020-09-23 | |
| US63/082,357 | 2020-09-23 | ||
| US202063124429P | 2020-12-11 | 2020-12-11 | |
| US63/124,429 | 2020-12-11 | ||
| US202163225673P | 2021-07-26 | 2021-07-26 | |
| US63/225,673 | 2021-07-26 | ||
| PCT/IB2021/058704 WO2022064428A1 (en) | 2020-09-23 | 2021-09-23 | Genetically engineered t cells with regnase-1 and/or tgfbrii disruption have improved functionality and persistence |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023542348A JP2023542348A (ja) | 2023-10-06 |
| JPWO2022064428A5 JPWO2022064428A5 (https=) | 2024-09-24 |
| JP2023542348A5 true JP2023542348A5 (https=) | 2024-09-24 |
Family
ID=78080385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023518205A Pending JP2023542348A (ja) | 2020-09-23 | 2021-09-23 | Ｒｅｇｎａｓｅ－１及び／又はＴＧＦＢＲＩＩを破壊した遺伝子操作されたＴ細胞は機能性及び持続性を改善させた |
Country Status (12)
| Country | Link |
|---|---|
| US (6) | US20220090012A1 (https=) |
| EP (2) | EP4176048B1 (https=) |
| JP (1) | JP2023542348A (https=) |
| KR (1) | KR20230074515A (https=) |
| CN (1) | CN116322716A (https=) |
| AU (1) | AU2021347907A1 (https=) |
| CA (1) | CA3192280A1 (https=) |
| ES (1) | ES2993268T3 (https=) |
| IL (1) | IL301012A (https=) |
| MX (1) | MX2023003365A (https=) |
| TW (1) | TW202229545A (https=) |
| WO (1) | WO2022064428A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021009357A (es) * | 2019-02-04 | 2021-11-17 | Ksq Therapeutics Inc | Dianas de genes de combinacion para mejorar la inmunoterapia. |
| AU2020232691B2 (en) | 2019-03-05 | 2023-06-29 | Nkarta, Inc. | CD19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| WO2021252804A1 (en) | 2020-06-12 | 2021-12-16 | Nkarta, Inc. | Genetically modified natural killer cells for cd70-directed cancer immunotherapy |
| WO2023007373A1 (en) * | 2021-07-26 | 2023-02-02 | Crispr Therapeutics Ag | Methods for manufacturing genetically engineered car-t cells |
| WO2023084399A1 (en) | 2021-11-09 | 2023-05-19 | Crispr Therapeutics Ag | Genetically engineered immune cells expressing masked chimeric antigen receptors specific to protein tyrosine kinase 7 |
| WO2023111913A1 (en) | 2021-12-15 | 2023-06-22 | Crispr Therapeutics Ag | Engineered anti-liv1 cell with regnase-1 and/or tgfbrii disruption |
| WO2023119201A2 (en) | 2021-12-22 | 2023-06-29 | Crispr Therapeutics Ag | Genetically engineered t cells with disrupted casitas b-lineage lymphoma proto-oncogene-b (cblb) and uses thereof |
| WO2023180968A1 (en) | 2022-03-23 | 2023-09-28 | Crispr Therapeutics Ag | Anti-cd19 car-t cells with multiple gene edits and therapeutic uses thereof |
| WO2023180967A1 (en) | 2022-03-23 | 2023-09-28 | Crispr Therapeutics Ag | Anti-cd83 car-t cells with regnase-1 and/or tgfbrii disruption |
| CN119451992A (zh) | 2022-06-29 | 2025-02-14 | 克里斯珀医疗股份公司 | 靶向gpc-3的嵌合抗原受体和表达其的免疫细胞用于治疗用途 |
| WO2024023801A2 (en) | 2022-07-29 | 2024-02-01 | Crispr Therapeutics Ag | Genetically engineered immune cells having disrupted transporter associated with antigen processing-1 (tap-1) gene |
| WO2024023802A2 (en) | 2022-07-29 | 2024-02-01 | Crispr Therapeutics Ag | Genetically engineered immune cells having disrupted transporter associated with antigen processing-2 (tap-2) gene |
| WO2024023804A2 (en) | 2022-07-29 | 2024-02-01 | Crispr Therapeutics Ag | Genetically engineered immune cells having disrupted transporter associated with antigen processing binding protein (tapbp) gene |
| WO2024059757A2 (en) * | 2022-09-14 | 2024-03-21 | Ohio State Innovation Foundation | Methods for reprograming exhausted t cells and boosting immune checkpoint blockade therapy for cancer |
| WO2024062388A2 (en) | 2022-09-20 | 2024-03-28 | Crispr Therapeutics Ag | Genetically engineered immune cells expressing chimeric antigen receptor targeting cd20 |
| US20240115703A1 (en) * | 2022-10-10 | 2024-04-11 | Crispr Therapeutics Ag | Genetically engineered anti-cd19 car-t cells for use in treating b-cell malignancies |
| WO2024229098A2 (en) * | 2023-05-01 | 2024-11-07 | Wisconsin Alumni Research Foundation | Methods and systems for predicting potent t cell products |
| US12500832B2 (en) | 2023-08-28 | 2025-12-16 | Ciena Corporation | Establishing and advertising co-routed bidirectional paths across multiple domains |
| WO2025126049A2 (en) | 2023-12-11 | 2025-06-19 | Crispr Therapeutics Ag | Multiplex gene editing |
| WO2025137439A2 (en) * | 2023-12-20 | 2025-06-26 | Intellia Therapeutics, Inc. | Engineered t cells |
| CN117844811A (zh) * | 2024-03-08 | 2024-04-09 | 上海恒润达生生物科技股份有限公司 | 靶向敲除CD70基因的sgRNA组合物及其应用 |
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| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5858358A (en) | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
| US7175843B2 (en) | 1994-06-03 | 2007-02-13 | Genetics Institute, Llc | Methods for selectively stimulating proliferation of T cells |
| US7067318B2 (en) | 1995-06-07 | 2006-06-27 | The Regents Of The University Of Michigan | Methods for transfecting T cells |
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| US12227763B2 (en) | 2018-05-11 | 2025-02-18 | Crispr Therapeutics Ag | Methods and compositions for treating cancer |
| EP3804759A4 (en) | 2018-06-06 | 2022-07-20 | Osaka University | METHODS OF TREATMENT OF DANDRUFF OR PREVENTION OF GNASE 1 SECONDARY DISEASES |
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| CN110904045A (zh) * | 2018-09-17 | 2020-03-24 | 中国科学院动物研究所 | 经修饰的t细胞、其制备方法及用途 |
| SG11202103832SA (en) | 2018-11-07 | 2021-05-28 | Crispr Therapeutics Ag | Anti-cd33 immune cell cancer therapy |
| US20220133790A1 (en) * | 2019-01-16 | 2022-05-05 | Beam Therapeutics Inc. | Modified immune cells having enhanced anti-neoplasia activity and immunosuppression resistance |
| US20220249558A1 (en) * | 2019-04-30 | 2022-08-11 | Crispr Therapeutics Ag | Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19 |
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| TW202132333A (zh) * | 2019-11-13 | 2021-09-01 | 瑞士商Ｃｒｉｓｐｒ治療公司 | 製造可表達嵌合抗原受體的ｔ細胞製法 |
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2021
- 2021-09-23 CN CN202180062948.8A patent/CN116322716A/zh active Pending
- 2021-09-23 IL IL301012A patent/IL301012A/en unknown
- 2021-09-23 EP EP21787042.7A patent/EP4176048B1/en active Active
- 2021-09-23 ES ES21787042T patent/ES2993268T3/es active Active
- 2021-09-23 TW TW110135390A patent/TW202229545A/zh unknown
- 2021-09-23 JP JP2023518205A patent/JP2023542348A/ja active Pending
- 2021-09-23 CA CA3192280A patent/CA3192280A1/en active Pending
- 2021-09-23 EP EP24162548.2A patent/EP4397321A3/en active Pending
- 2021-09-23 WO PCT/IB2021/058704 patent/WO2022064428A1/en not_active Ceased
- 2021-09-23 MX MX2023003365A patent/MX2023003365A/es unknown
- 2021-09-23 KR KR1020237013253A patent/KR20230074515A/ko not_active Withdrawn
- 2021-09-23 US US17/483,100 patent/US20220090012A1/en not_active Abandoned
- 2021-09-23 AU AU2021347907A patent/AU2021347907A1/en active Pending
- 2021-10-04 US US17/493,271 patent/US11679131B2/en active Active
- 2021-10-04 US US17/493,280 patent/US11497773B2/en active Active
- 2021-10-04 US US17/493,253 patent/US11679130B2/en active Active
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2022
- 2022-11-10 US US18/054,521 patent/US11857574B2/en active Active
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2025
- 2025-02-18 US US19/056,007 patent/US20250179146A1/en active Pending