IL301012A - Genetically engineered T cells with a REGNASE-1 and/or TGFBRII disorder with improved functionality and persistence - Google Patents

Genetically engineered T cells with a REGNASE-1 and/or TGFBRII disorder with improved functionality and persistence

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Publication number
IL301012A
IL301012A IL301012A IL30101223A IL301012A IL 301012 A IL301012 A IL 301012A IL 301012 A IL301012 A IL 301012A IL 30101223 A IL30101223 A IL 30101223A IL 301012 A IL301012 A IL 301012A
Authority
IL
Israel
Prior art keywords
cells
gene
car
tgfbrii
seq
Prior art date
Application number
IL301012A
Other languages
English (en)
Hebrew (he)
Original Assignee
Crispr Therapeutics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crispr Therapeutics Ag filed Critical Crispr Therapeutics Ag
Publication of IL301012A publication Critical patent/IL301012A/en

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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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