JP2018523484A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018523484A5 JP2018523484A5 JP2018509542A JP2018509542A JP2018523484A5 JP 2018523484 A5 JP2018523484 A5 JP 2018523484A5 JP 2018509542 A JP2018509542 A JP 2018509542A JP 2018509542 A JP2018509542 A JP 2018509542A JP 2018523484 A5 JP2018523484 A5 JP 2018523484A5
- Authority
- JP
- Japan
- Prior art keywords
- car
- cell
- nucleic acid
- acid sequence
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1514874.5 | 2015-08-20 | ||
| GBGB1514874.5A GB201514874D0 (en) | 2015-08-20 | 2015-08-20 | Cell |
| PCT/GB2016/052563 WO2017029511A1 (en) | 2015-08-20 | 2016-08-19 | Cell |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020194900A Division JP2021027841A (ja) | 2015-08-20 | 2020-11-25 | 細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018523484A JP2018523484A (ja) | 2018-08-23 |
| JP2018523484A5 true JP2018523484A5 (https=) | 2019-07-25 |
| JP7395249B2 JP7395249B2 (ja) | 2023-12-11 |
Family
ID=54292002
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018509542A Active JP7395249B2 (ja) | 2015-08-20 | 2016-08-19 | 細胞 |
| JP2020194900A Withdrawn JP2021027841A (ja) | 2015-08-20 | 2020-11-25 | 細胞 |
| JP2023180246A Pending JP2023178386A (ja) | 2015-08-20 | 2023-10-19 | 細胞 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020194900A Withdrawn JP2021027841A (ja) | 2015-08-20 | 2020-11-25 | 細胞 |
| JP2023180246A Pending JP2023178386A (ja) | 2015-08-20 | 2023-10-19 | 細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11365262B2 (https=) |
| EP (1) | EP3337501A1 (https=) |
| JP (3) | JP7395249B2 (https=) |
| CN (1) | CN108135984A (https=) |
| AU (1) | AU2016308617A1 (https=) |
| CA (1) | CA2995775A1 (https=) |
| GB (1) | GB201514874D0 (https=) |
| HK (1) | HK1250667A1 (https=) |
| WO (1) | WO2017029511A1 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP2948544A4 (en) | 2013-01-28 | 2016-08-03 | St Jude Childrens Res Hospital | CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES |
| DK3143134T3 (da) | 2014-05-15 | 2021-01-04 | Nat Univ Singapore | Modificerede, naturlige dræberceller og anvendelser deraf |
| EP3439675A4 (en) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| GB201620070D0 (en) * | 2016-11-28 | 2017-01-11 | Autolus Ltd | Signal transduction modifying protein |
| US11578115B2 (en) | 2017-01-10 | 2023-02-14 | The General Hospital Corporation | Chimeric antigen receptors based on alternative signal 1 domains |
| US11649288B2 (en) | 2017-02-07 | 2023-05-16 | Seattle Children's Hospital | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| CN118599009A (zh) | 2017-03-16 | 2024-09-06 | 综合医院公司 | 靶向cd37的嵌合抗原受体 |
| BR112019019917A2 (pt) | 2017-03-27 | 2020-04-22 | Nat Univ Singapore | receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais |
| CA3056591A1 (en) | 2017-03-27 | 2018-10-04 | National University Of Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
| US11596655B2 (en) | 2017-04-27 | 2023-03-07 | Washington University | Activation of natural cytotoxicity receptor 2 (NCR2) |
| US20210130775A1 (en) * | 2017-08-02 | 2021-05-06 | Autolus Limited | Cells expressing a chimeric antigen receptor or engineered tcr and comprising a nucleotide sequence which is selectively expressed |
| WO2019086394A1 (en) * | 2017-11-01 | 2019-05-09 | F. Hoffmann-La Roche Ag | The compbody - a multivalent target binder |
| US20190192678A1 (en) * | 2017-12-18 | 2019-06-27 | Novather, Inc. | System and method for the treatment of disease using a hyperspecific modified protein system |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| GB201801831D0 (en) * | 2018-02-05 | 2018-03-21 | Autolus Ltd | Chimeric receptor |
| US12312416B2 (en) | 2018-02-06 | 2025-05-27 | Seattle Children's Hospital | Fluorescein-specific cars exhibiting optimal t cell function against FL-PLE labelled tumors |
| EP3749685A4 (en) | 2018-02-09 | 2021-12-22 | National University of Singapore | ACTIVATOR CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLING CELL IMMUNOTHERAPY |
| AU2019225174B2 (en) | 2018-02-23 | 2025-11-20 | Endocyte, Inc. | Sequencing method for CAR T cell therapy |
| JP7334985B2 (ja) | 2018-04-02 | 2023-08-29 | ナショナル ユニヴァーシティー オブ シンガポール | 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和 |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| IL281428B2 (en) | 2018-09-27 | 2024-10-01 | Autolus Ltd | Chimeric antigen receptor |
| CA3120563A1 (en) | 2018-11-26 | 2020-06-04 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| US20220259281A1 (en) * | 2019-06-21 | 2022-08-18 | Shattuck Labs, Inc. | Chimeric protein expressing t-cells |
| WO2021007580A1 (en) * | 2019-07-11 | 2021-01-14 | Valkyr, Inc. | System and methods relating to chimeric autoantibody receptors |
| CN112779223B (zh) * | 2019-11-08 | 2024-06-11 | 浙江煦顼技术有限公司 | 偶联嵌合抗原受体细胞及其用途 |
| CN115210252A (zh) | 2020-02-04 | 2022-10-18 | 西雅图儿童医院（Dba西雅图儿童研究所） | 抗二硝基苯酚的嵌合抗原受体 |
| GB202008688D0 (en) * | 2020-06-09 | 2020-07-22 | Cancer Research Tech Ltd | Chimeric antigen receptor cell |
| IL322949A (en) | 2023-03-03 | 2025-10-01 | Arsenal Biosciences Inc | Systems targeting PSMA and CA9 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010085660A2 (en) * | 2009-01-23 | 2010-07-29 | Roger Williams Hospital | Viral vectors encoding multiple highly homologous non-viral polypeptides and the use of same |
| CA2861491C (en) | 2012-02-13 | 2020-08-25 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Bispecific chimeric antigen receptors and therapeutic uses thereof |
| WO2014145252A2 (en) | 2013-03-15 | 2014-09-18 | Milone Michael C | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| MX373687B (es) * | 2013-11-21 | 2020-07-07 | Ucl Business Ltd | Célula natural (nk) |
| ES2918501T3 (es) | 2013-12-19 | 2022-07-18 | Novartis Ag | Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos |
| US20170335281A1 (en) * | 2014-03-15 | 2017-11-23 | Novartis Ag | Treatment of cancer using chimeric antigen receptor |
| GB201513540D0 (en) | 2015-07-31 | 2015-09-16 | King S College London | Therapeutic agents |
-
2015
- 2015-08-20 GB GBGB1514874.5A patent/GB201514874D0/en not_active Ceased
-
2016
- 2016-08-19 US US15/753,505 patent/US11365262B2/en active Active
- 2016-08-19 HK HK18110271.9A patent/HK1250667A1/zh unknown
- 2016-08-19 CA CA2995775A patent/CA2995775A1/en not_active Abandoned
- 2016-08-19 WO PCT/GB2016/052563 patent/WO2017029511A1/en not_active Ceased
- 2016-08-19 CN CN201680046855.5A patent/CN108135984A/zh active Pending
- 2016-08-19 JP JP2018509542A patent/JP7395249B2/ja active Active
- 2016-08-19 EP EP16756757.7A patent/EP3337501A1/en active Pending
- 2016-08-19 AU AU2016308617A patent/AU2016308617A1/en not_active Abandoned
-
2020
- 2020-11-25 JP JP2020194900A patent/JP2021027841A/ja not_active Withdrawn
-
2023
- 2023-10-19 JP JP2023180246A patent/JP2023178386A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018523484A5 (https=) | ||
| JP7822340B2 (ja) | キメラ抗原受容体およびその使用 | |
| JP2016538855A5 (https=) | ||
| JP2019535262A5 (https=) | ||
| RU2016124278A (ru) | Клетка | |
| JP2016538854A5 (https=) | ||
| JP2022109953A5 (https=) | ||
| JP2019150066A5 (https=) | ||
| JP2021035395A5 (https=) | ||
| CN112638947B (zh) | 用于治疗实体瘤的嵌合抗原受体细胞 | |
| JP2021137013A (ja) | 修飾ｔ細胞に対する条件的活性型キメラ抗原受容体 | |
| KR102588292B1 (ko) | 항-bcma 키메라 항원 수용체 | |
| US20200368268A1 (en) | Immune-enhancing rnas for combination with chimeric antigen receptor therapy | |
| RU2017121892A (ru) | Клетка | |
| JP2018501794A5 (https=) | ||
| JP2018517410A5 (https=) | ||
| JP2015518479A5 (https=) | ||
| JP2018521663A (ja) | 治療薬 | |
| CN110461335A (zh) | 用于治疗bcma相关癌症和自身免疫性失调的联合疗法 | |
| JP2019514393A (ja) | 細胞に基づくネオ抗原ワクチンおよびその使用 | |
| JP7227630B2 (ja) | Ｙ１８２ｔ突然変異を有するｔ細胞－抗原カプラおよびその方法ならびに使用 | |
| JP2018523484A (ja) | 細胞 | |
| JP2017537622A5 (https=) | ||
| JP2017513478A5 (https=) | ||
| JP2019524100A5 (https=) |