ZA975326B - Device and method for enhancing transdermal flux of agents being delivered or sampled. - Google Patents

Device and method for enhancing transdermal flux of agents being delivered or sampled.

Info

Publication number
ZA975326B
ZA975326B ZA9705326A ZA975326A ZA975326B ZA 975326 B ZA975326 B ZA 975326B ZA 9705326 A ZA9705326 A ZA 9705326A ZA 975326 A ZA975326 A ZA 975326A ZA 975326 B ZA975326 B ZA 975326B
Authority
ZA
South Africa
Prior art keywords
sampled
delivered
agents
transdermal flux
enhancing transdermal
Prior art date
Application number
ZA9705326A
Other languages
English (en)
Inventor
Michel J N Cormier
Armand P Neukermans
Barry Block
Felix T Theeuwes
Alfred A Amkraut
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of ZA975326B publication Critical patent/ZA975326B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A61B5/150427—Specific tip design, e.g. for improved penetration characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15105—Purely manual piercing, i.e. the user pierces the skin without the assistance of any driving means or driving devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A61B5/15113—Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15142—Devices intended for single use, i.e. disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Manufacturing & Machinery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Optics & Photonics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Prostheses (AREA)
ZA9705326A 1996-06-18 1997-06-17 Device and method for enhancing transdermal flux of agents being delivered or sampled. ZA975326B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1999096P 1996-06-18 1996-06-18

Publications (1)

Publication Number Publication Date
ZA975326B true ZA975326B (en) 1998-01-14

Family

ID=21796163

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9705326A ZA975326B (en) 1996-06-18 1997-06-17 Device and method for enhancing transdermal flux of agents being delivered or sampled.

Country Status (14)

Country Link
US (5) US7184826B2 (fr)
EP (3) EP0914178B1 (fr)
JP (4) JP4012252B2 (fr)
AR (2) AR008242A1 (fr)
AT (3) ATE234129T1 (fr)
AU (3) AU3399197A (fr)
CA (3) CA2253549C (fr)
DE (3) DE69719761T2 (fr)
DK (3) DK0914178T3 (fr)
ES (3) ES2195151T3 (fr)
PT (2) PT917483E (fr)
TW (1) TW349872B (fr)
WO (3) WO1997048440A1 (fr)
ZA (1) ZA975326B (fr)

Families Citing this family (742)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593852A (en) * 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
CA2050057A1 (fr) 1991-03-04 1992-09-05 Adam Heller Biocapteurs d'elimination d'impuretes
AU5869796A (en) * 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
CA2253549C (fr) * 1996-06-18 2005-10-25 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
US6607509B2 (en) * 1997-12-31 2003-08-19 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
AU739616B2 (en) * 1997-12-11 2001-10-18 Alza Corporation Device for enhancing transdermal agent flux
CN1206004C (zh) 1997-12-11 2005-06-15 阿尔扎有限公司 增强透皮物剂流量的装置
EP1911488A3 (fr) 1997-12-11 2008-12-03 Alza Corporation Dispositif pour améliorer le flux d'agent transdermique
KR100561892B1 (ko) 1997-12-11 2006-03-16 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
JP4368060B2 (ja) * 1998-02-17 2009-11-18 アボット・ラボラトリーズ 間質流体の収集及びモニタリングデバイス
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6757560B1 (en) * 1999-04-09 2004-06-29 Novosis Pharma Ag Transdermal delivery system (TDS) with electrode network
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
CA2332112C (fr) * 1998-05-13 2004-02-10 Cygnus, Inc. Controle d'analytes physiologiques
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US7922709B2 (en) 1998-07-13 2011-04-12 Genetronics, Inc. Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation
US6355021B1 (en) * 1998-07-14 2002-03-12 Maersk Medical A/S Medical puncturing device
MXPA01000698A (es) * 1998-07-21 2002-04-08 Spectrx Inc Sistema y metodo para el monitoreo de analito continuo.
EP1109594B1 (fr) * 1998-08-31 2004-10-27 Johnson & Johnson Consumer Companies, Inc. Dispositif d'electrotransport comprenant des lames
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6603998B1 (en) * 1999-01-28 2003-08-05 Cyto Pulse Sciences, Inc. Delivery of macromolecules into cells
DE19903876B4 (de) * 1999-02-01 2006-09-28 Orthogen Gentechnologie Gmbh Verfahren zur in-vitro-Bildung und Anreicherung von Interleukin-1 Rezeptor-Antagonisten
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6856821B2 (en) * 2000-05-26 2005-02-15 Kci Licensing, Inc. System for combined transcutaneous blood gas monitoring and vacuum assisted wound closure
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6251083B1 (en) 1999-09-07 2001-06-26 Amira Medical Interstitial fluid methods and devices for determination of an analyte in the body
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US6331266B1 (en) 1999-09-29 2001-12-18 Becton Dickinson And Company Process of making a molded device
WO2001041863A1 (fr) 1999-12-10 2001-06-14 Alza Corporation Dispositif et procede d'amelioration de percage de peau par micro-protuberances
PT1239775E (pt) * 1999-12-16 2005-05-31 Alza Corp Dispositivo para aumentar o fluxo transdermal de amostras de agentes
US7013179B2 (en) 2000-01-07 2006-03-14 Biowave Corporation Percutaneous electrode array
US20080033492A1 (en) * 2000-01-07 2008-02-07 Biowave Corporation Electro-therapy method
US6622035B1 (en) * 2000-01-21 2003-09-16 Instrumentarium Corp. Electrode for measurement of weak bioelectrical signals
WO2001052731A1 (fr) * 2000-01-21 2001-07-26 Instrumentarium Corporation Electrode medicale
AU781149B2 (en) * 2000-03-17 2005-05-05 Echo Therapeutics, Inc. System, method, and device for non-invasive body fluid sampling and analysis
US7404815B2 (en) * 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6595947B1 (en) 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6537242B1 (en) 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US9717451B2 (en) 2000-06-08 2017-08-01 Becton, Dickinson And Company Device for withdrawing or administering a substance and method of manufacturing a device
US6607513B1 (en) 2000-06-08 2003-08-19 Becton, Dickinson And Company Device for withdrawing or administering a substance and method of manufacturing a device
US6540675B2 (en) * 2000-06-27 2003-04-01 Rosedale Medical, Inc. Analyte monitor
US6589202B1 (en) 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
US6603987B2 (en) * 2000-07-11 2003-08-05 Bayer Corporation Hollow microneedle patch
US6440096B1 (en) 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
US6656147B1 (en) 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
JP2004506914A (ja) 2000-08-24 2004-03-04 アルザ・コーポレーシヨン 経皮的核酸サンプリング方法
US6749575B2 (en) 2001-08-20 2004-06-15 Alza Corporation Method for transdermal nucleic acid sampling
US6690959B2 (en) 2000-09-01 2004-02-10 Medtronic, Inc. Skin-mounted electrodes with nano spikes
EE200300095A (et) * 2000-09-08 2005-02-15 Alza Corporation Ravimi transdermaalse transpordi vähenemise pärssimise meetodid kanalite sulgumise pärssimisega
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
AU2002210881A1 (en) 2000-10-12 2002-04-22 Ink Jet Technology Ltd. Transdermal method
MXPA03003301A (es) 2000-10-13 2004-12-13 Johnson & Johnson Aplicador de un conjunto de microsalientes mediante impacto.
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
JP4104975B2 (ja) * 2000-10-13 2008-06-18 アルザ・コーポレーシヨン 衝撃適用装置用の微小突起部材保持器
PL360998A1 (en) * 2000-10-13 2004-09-20 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
PL211151B1 (pl) 2000-10-18 2012-04-30 Glaxosmithkline Biolog Sa Kompozycja immunogenna oraz zastosowanie połączenia saponiny, oligonukleotydu immunostymulującego i lipopolisacharydu
CA2427381A1 (fr) * 2000-10-26 2002-11-28 Alza Corporation Dispositifs d'administration de medicament transdermique avec des microprotrusions enrobees
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
DE10057832C1 (de) * 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
US6591133B1 (en) * 2000-11-27 2003-07-08 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
WO2002064193A2 (fr) * 2000-12-14 2002-08-22 Georgia Tech Research Corporation Appareils a microaiguilles et fabrication
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
WO2003106964A2 (fr) * 2001-01-10 2003-12-24 Dermal Systems International Inc. Procedes et dispositifs a haut rendement permettant de doser des analytes dans un echantillon fluidique
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
US6932933B2 (en) * 2001-03-30 2005-08-23 The Aerospace Corporation Ultraviolet method of embedding structures in photocerams
EP1397068A2 (fr) 2001-04-02 2004-03-17 Therasense, Inc. Dispositif et procede de recherche de glucose dans le sang
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
EP3251722B1 (fr) 2001-04-20 2020-06-17 ALZA Corporation Réseau de microprojections ayant un revêtement contenant un agent bénéfique et procédé de revêtement
IL158480A0 (en) * 2001-04-20 2004-05-12 Alza Corp Microprojection array having a beneficial agent containing coating
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US6855117B2 (en) 2001-08-01 2005-02-15 Johnson & Johnson Consumer Companies, Inc. Method of treating the skin of a subject
US6840910B2 (en) 2001-08-01 2005-01-11 Johnson & Johnson Consumer Companies, Inc. Method of distributing skin care products
US6790179B2 (en) 2001-08-01 2004-09-14 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
JP2004532698A (ja) 2001-06-08 2004-10-28 ベクトン・ディキンソン・アンド・カンパニー ニードルまたはアブレーダーアレイの操作のための装置
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
JP4149911B2 (ja) 2001-06-12 2008-09-17 ペリカン テクノロジーズ インコーポレイテッド 電気式ランセットアクチュエータ
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
AU2002315177A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
WO2002100254A2 (fr) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Procede et appareil pour un dispositif de lancement de lancette integre sur une cartouche de prelevement de sang
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
WO2002102273A2 (fr) * 2001-06-20 2002-12-27 Power Paper Ltd. Bandage adhesif muni d'un afficheur
CN1310618C (zh) * 2001-07-19 2007-04-18 爱科来株式会社 穿刺装置
US20030028087A1 (en) * 2001-08-01 2003-02-06 Yuzhakov Vadim Vladimirovich Devices for analyte concentration determination and methods of using the same
SE0102736D0 (sv) * 2001-08-14 2001-08-14 Patrick Griss Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles
US6881203B2 (en) * 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
WO2003022330A2 (fr) 2001-09-12 2003-03-20 Becton, Dickinson And Company Stylo a micro-aiguille pour l'administration de medicaments et procede d'utilisation associe
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
AU2002327675A1 (en) * 2001-09-19 2003-04-01 Biovalve Technologies, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
US20070179717A1 (en) * 2001-09-21 2007-08-02 Milliken Gordon L System and method for management of specimens
US6830562B2 (en) * 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US20030135166A1 (en) * 2001-09-28 2003-07-17 Gonnelli Robert R. Switchable microneedle arrays and systems and methods relating to same
US20030135201A1 (en) * 2001-09-28 2003-07-17 Gonnelli Robert R. Microneedle with membrane
US6689100B2 (en) 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US20030069482A1 (en) * 2001-10-09 2003-04-10 Workman Jerome James Sampling article for determining quantitative and qualitative drug transfer to skin
US6966880B2 (en) * 2001-10-16 2005-11-22 Agilent Technologies, Inc. Universal diagnostic platform
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
AU2002353444A1 (en) * 2001-11-07 2003-05-19 Transpharma Medical Ltd. Integrated transdermal drug delivery system
AU2002352978A1 (en) * 2001-11-30 2003-06-17 Alza Corporation Methods and apparatuses for forming microprojection arrays
ES2297056T3 (es) * 2001-12-20 2008-05-01 Alza Corporation Micro-proyecciones para perforacion de la piel que tienen control de la profundidad de perforacion.
ITTO20011228A1 (it) * 2001-12-28 2003-06-28 Cane Srl Contenitore per ago monouso.
US20040073175A1 (en) * 2002-01-07 2004-04-15 Jacobson James D. Infusion system
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
CA2474742C (fr) * 2002-02-04 2012-01-17 Becton, Dickinson And Company Element d'acces dermique
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7497827B2 (en) 2004-07-13 2009-03-03 Dexcom, Inc. Transcutaneous analyte sensor
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7147623B2 (en) * 2002-02-12 2006-12-12 Unomedical A/S Infusion device with needle shield
US8116860B2 (en) 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
US9918665B2 (en) 2002-03-11 2018-03-20 Nitto Denko Corporation Transdermal porator and patch system and method for using same
US7392080B2 (en) 2002-03-11 2008-06-24 Altea Therapeutics Corporation Transdermal drug delivery patch system, method of making same and method of using same
US7047070B2 (en) 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
CN1655834A (zh) 2002-05-06 2005-08-17 贝克顿·迪金森公司 用于控制药代动力学的方法和装置
GB0210397D0 (en) * 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US7060192B2 (en) * 2002-05-09 2006-06-13 Lifescan, Inc. Methods of fabricating physiological sample collection devices
US20030212344A1 (en) * 2002-05-09 2003-11-13 Vadim Yuzhakov Physiological sample collection devices and methods of using the same
US20030211619A1 (en) * 2002-05-09 2003-11-13 Lorin Olson Continuous strip of fluid sampling and testing devices and methods of making, packaging and using the same
US20030143113A2 (en) * 2002-05-09 2003-07-31 Lifescan, Inc. Physiological sample collection devices and methods of using the same
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
JP2005533625A (ja) * 2002-07-19 2005-11-10 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルデバイスおよびマイクロニードル送達装置
AR040819A1 (es) * 2002-08-08 2005-04-20 Alza Corp Dispositivo de administracion transdermica de vacuna que tiene microproyecciones revestidas
EP1531896B1 (fr) 2002-08-29 2016-07-20 Becton Dickinson and Company Matrices de microprotuberances et procede permettant d'utiliser ces matrices pour l'administration de substances a un tissu
AU2003258487A1 (en) * 2002-09-02 2004-03-19 Unomedical A/S A device for subcutaneous administration of a medicament to a patient
ATE376856T1 (de) * 2002-09-02 2007-11-15 Unomedical As Gerät und verfahren zur einstellung der länge eines infusionsschlauchs
WO2004020035A1 (fr) * 2002-09-02 2004-03-11 Unomedical A/S Dispositif d'administration sous-cutanee d'un medicament a un patient et tubulure destinee audit dispositif
US20040051019A1 (en) * 2002-09-02 2004-03-18 Mogensen Lasse Wesseltoft Apparatus for and a method of adjusting the length of an infusion tube
US20120296233A9 (en) * 2002-09-05 2012-11-22 Freeman Dominique M Methods and apparatus for an analyte detecting device
WO2004024224A1 (fr) * 2002-09-16 2004-03-25 Sung-Yun Kwon Micro-perforateurs solides et leurs procede d'utilisation
US20040236269A1 (en) 2002-09-25 2004-11-25 Marchitto Kevin S. Microsurgical tissue treatment system
EP1590033A2 (fr) * 2002-09-30 2005-11-02 Alza Corporation Methode et dispositif d'administration de medicaments presentant des microprojections revetues comprenant des vasoconstricteurs
US7244394B2 (en) * 2002-10-03 2007-07-17 Novartis Ag Methods and kits for assays of analytes of interest in tears
EP1590034B1 (fr) 2002-10-07 2014-05-14 Biovalve Technologies, Inc. Emplatre a serie de micro-aiguilles
WO2005061041A1 (fr) * 2002-10-11 2005-07-07 Becton, Dickinson And Company Systeme d'administration d'insuline equipe d'un capteur
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US7045069B2 (en) * 2002-11-14 2006-05-16 Gennady Ozeryansky Microfabrication method based on metal matrix composite technology
DK200201823A (da) 2002-11-26 2004-05-27 Maersk Medical As Forbindelsesstykke for en slangeforbindelse
US7018345B2 (en) * 2002-12-06 2006-03-28 Hisamitsu Pharmaceutical Co., Inc. Iontophoresis system
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
US20040158202A1 (en) * 2003-02-12 2004-08-12 Soren Jensen Cover
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US7052652B2 (en) 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
US20050070819A1 (en) * 2003-03-31 2005-03-31 Rosedale Medical, Inc. Body fluid sampling constructions and techniques
US7070580B2 (en) * 2003-04-01 2006-07-04 Unomedical A/S Infusion device and an adhesive sheet material and a release liner
US20040265351A1 (en) * 2003-04-10 2004-12-30 Miller Richard L. Methods and compositions for enhancing immune response
US7415299B2 (en) * 2003-04-18 2008-08-19 The Regents Of The University Of California Monitoring method and/or apparatus
JP2004343275A (ja) * 2003-05-14 2004-12-02 Murata Mach Ltd 画像処理システム及びスキャナ装置
EP1628567B1 (fr) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Procede et appareil pour injection de fluide
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
WO2006001797A1 (fr) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Element penetrant peu douloureux
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
AU2004253571A1 (en) * 2003-07-02 2005-01-13 Alza Corporation Microprojection array immunization patch and method
EP1648363B1 (fr) * 2003-07-03 2019-03-06 Corium International, Inc. Pansement, dispositif d'administration d'ingredient et dispositif de fixation intraveineux et procede associe
US7695239B2 (en) * 2003-07-14 2010-04-13 Fortrend Engineering Corporation End effector gripper arms having corner grippers which reorient reticle during transfer
WO2005007223A2 (fr) * 2003-07-16 2005-01-27 Sasha John Systemes et procedes d'administration programmable de medicaments pour l'administration de fluides et de concentrations multiples
US7467003B2 (en) * 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7460898B2 (en) * 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7424318B2 (en) 2003-12-05 2008-09-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7366556B2 (en) 2003-12-05 2008-04-29 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7761130B2 (en) * 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US20050049549A1 (en) * 2003-08-04 2005-03-03 Wong Patrick S.L. Method and device for enhancing transdermal agent flux
US7223248B2 (en) * 2003-08-13 2007-05-29 Lifescan, Inc. Packaged medical device with a deployable dermal tissue penetration member
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US8233959B2 (en) 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
CN1842355A (zh) * 2003-08-26 2006-10-04 阿尔扎公司 用于皮内细胞植入的装置和方法
US7099968B2 (en) * 2003-09-02 2006-08-29 Intel Corporation System and method for generating bus requests in advance based on speculation states
US8353861B2 (en) * 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
EP1671096A4 (fr) 2003-09-29 2009-09-16 Pelikan Technologies Inc Procede et appareil permettant d'obtenir un dispositif de capture d'echantillons ameliore
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
AU2004285484A1 (en) * 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
JP2007508914A (ja) * 2003-10-24 2007-04-12 アルザ・コーポレーシヨン 経皮薬剤送達を促進するための装置及び方法
CN1897882A (zh) 2003-10-28 2007-01-17 阿尔扎公司 降低烟草使用频率的方法和装置
US7097631B2 (en) * 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
USD902408S1 (en) 2003-11-05 2020-11-17 Abbott Diabetes Care Inc. Analyte sensor control unit
EP1682217A4 (fr) * 2003-11-13 2008-04-30 Alza Corp Systeme et methode d'administration transdermique
DE10353629A1 (de) * 2003-11-17 2005-06-16 Lts Lohmann Therapie-Systeme Ag Vorrichtung zur transdermalen Verabreichung von Wirkstoffen
JP2007511318A (ja) * 2003-11-18 2007-05-10 ナノ パス テクノロジーズ リミテッド 改良された挿入システム及びマイクロニードルを摺動させるための方法
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8615282B2 (en) 2004-07-13 2013-12-24 Dexcom, Inc. Analyte sensor
US20050112135A1 (en) * 2003-11-21 2005-05-26 Cormier Michel J. Ultrasound assisted transdermal vaccine delivery method and system
US7753888B2 (en) * 2003-11-21 2010-07-13 The Regents Of The University Of California Method and/or apparatus for puncturing a surface for extraction, in situ analysis, and/or substance delivery using microneedles
CN1886171A (zh) * 2003-11-28 2006-12-27 艾克若克斯Dds有限公司 快速经皮施用的方法和系统
US8774886B2 (en) 2006-10-04 2014-07-08 Dexcom, Inc. Analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP2256493B1 (fr) 2003-12-05 2014-02-26 DexCom, Inc. Techniques d'étalonnage pour capteur d'analytes en continu
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8017145B2 (en) * 2003-12-22 2011-09-13 Conopco, Inc. Exfoliating personal care wipe article containing an array of projections
WO2005065414A2 (fr) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Procede et appareil permettant d'ameliorer le flux fluidique et le prelevement d'echantillons
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
US20080312555A1 (en) * 2004-02-06 2008-12-18 Dirk Boecker Devices and methods for glucose measurement using rechargeable battery energy sources
CA2556331A1 (fr) 2004-02-17 2005-09-29 Therasense, Inc. Procede et systeme de communication de donnees dans un systeme de controle et de gestion de glucose en continu
JP2007523771A (ja) * 2004-02-23 2007-08-23 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの成形方法
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
WO2009048462A1 (fr) 2007-10-09 2009-04-16 Dexcom, Inc. Système d'administration d'insuline intégré avec un capteur de glucose en continu
WO2005094526A2 (fr) * 2004-03-24 2005-10-13 Corium International, Inc. Dispositif d'administration transdermique
EP1727576B1 (fr) 2004-03-26 2009-03-04 Unomedical A/S Systeme de perfusion
MXPA06011971A (es) * 2004-04-13 2007-04-16 Johnson & Johnson Aparato y metodo para suministro transdermico de multiples vacunas.
US20070184222A1 (en) * 2004-04-20 2007-08-09 University Of Rochester Hydrogel-supported porous semiconductor devices
EP1744683B1 (fr) * 2004-05-13 2016-03-16 Alza Corporation Appareil et procédé pour la délivrance transdermique d'agents à base d'hormone parathyroïde
MXPA06013490A (es) * 2004-05-19 2007-06-12 Johnson & Johnson Metodo y formulacion para el suministro transdermico de agentes inmunologicamente activos.
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9820684B2 (en) 2004-06-03 2017-11-21 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US7315758B2 (en) 2004-06-03 2008-01-01 Lynntech, Inc. Transdermal delivery of therapeutic agent
CA2858901C (fr) 2004-06-04 2024-01-16 Carolyn Anderson Architecture hote-client de soins pour le diabete et systemes de gestion de donnees
US20050273075A1 (en) * 2004-06-08 2005-12-08 Peter Krulevitch Method for delivering drugs to the adventitia using device having microprojections
US20050273049A1 (en) * 2004-06-08 2005-12-08 Peter Krulevitch Drug delivery device using microprojections
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US20060016700A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US20070045902A1 (en) 2004-07-13 2007-03-01 Brauker James H Analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
WO2006015299A2 (fr) * 2004-07-30 2006-02-09 Microchips, Inc. Dispositif multi-reservoir pour la delivrance de medicament transdermique et la detection
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
US20060030788A1 (en) * 2004-08-04 2006-02-09 Daniel Wong Apparatus and method for extracting bodily fluid utilizing a flat lancet
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
US20060058602A1 (en) * 2004-08-17 2006-03-16 Kwiatkowski Krzysztof C Interstitial fluid analyzer
EP1781123A1 (fr) * 2004-08-23 2007-05-09 U.S. Smokeless Tobacco Company Compositions de nicotine
EP1786505A1 (fr) * 2004-09-08 2007-05-23 Alza Corporation Reseau de protuberances microscopiques possedant une adherence a la peau et une conformite ameliorees
KR101359930B1 (ko) 2004-09-22 2014-02-12 글락소스미스클라인 바이오로지칼즈 에스.에이. 스태필로코쿠스에 대한 예방접종에 사용하기 위한 면역원성조성물
TW200626177A (en) * 2004-09-28 2006-08-01 Alza Corp Method and formulation for stabilizing alum-adsorbed vaccines
ITPD20040252A1 (it) * 2004-10-14 2005-01-14 Bidoia Sas Di Gianfranco Bidoi Irrigatore chirurgico
JP4416625B2 (ja) * 2004-10-29 2010-02-17 シスメックス株式会社 組織切断器具、組織切断補助器具および収納容器
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
EP1833547A1 (fr) 2004-11-18 2007-09-19 3M Innovative Properties Company Applicateur de jeux de micro-aiguilles a profil bas
EP1827564B1 (fr) * 2004-11-18 2015-07-29 3M Innovative Properties Company Procede de masquage pour le revetement d'un jeu de micro-aiguilles
JP4927752B2 (ja) * 2004-11-18 2012-05-09 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイアプリケーターおよび保持装置
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
CN100367906C (zh) * 2004-12-08 2008-02-13 圣美迪诺医疗科技(湖州)有限公司 皮下植入式生物传感器
JP4964141B2 (ja) * 2004-12-10 2012-06-27 ウノメディカル アクティーゼルスカブ 挿入具
WO2006077742A1 (fr) * 2004-12-28 2006-07-27 Nabtesco Corporation Dispositif de production d'aiguilles epidermiques et leur procede de production
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US8613703B2 (en) * 2007-05-31 2013-12-24 Abbott Diabetes Care Inc. Insertion devices and methods
US9636450B2 (en) 2007-02-19 2017-05-02 Udo Hoss Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US20090082693A1 (en) * 2004-12-29 2009-03-26 Therasense, Inc. Method and apparatus for providing temperature sensor module in a data communication system
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US8029441B2 (en) * 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US8571624B2 (en) 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
EP1846095A4 (fr) * 2005-01-20 2014-03-05 Epley Medical Llc Systeme d'administration de medicament intra-tympanique soutenue, a invasion minimale
CN101119764A (zh) * 2005-02-16 2008-02-06 阿尔扎公司 具有改善的生物相容性的微突出物阵列
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
NZ560546A (en) * 2005-03-21 2010-03-26 Unomedical As A mounting pad, an adhesive device comprising such mounting pad, and methods of preparing such devices
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
US8280476B2 (en) * 2005-03-29 2012-10-02 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
US20080009802A1 (en) * 2005-04-25 2008-01-10 Danilo Lambino Method of treating acne with stratum corneum piercing device
US20060253079A1 (en) * 2005-04-25 2006-11-09 Mcdonough Justin Stratum corneum piercing device
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
WO2007000162A2 (fr) * 2005-06-28 2007-01-04 Unomedical A/S Emballage pour systeme de perfusion, et procede d'application d'un systeme de perfusion
US20070004989A1 (en) * 2005-06-29 2007-01-04 Parvinder Dhillon Device for transdermal sampling
US20070025869A1 (en) * 2005-07-15 2007-02-01 Gordon John H Fluid Delivery Device
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
EP1921980A4 (fr) 2005-08-31 2010-03-10 Univ Virginia Amelioration de la precision de capteurs de glucose en continu
AU2006287603B2 (en) * 2005-09-06 2012-05-10 Theraject, Inc. Solid solution perforator containing drug particle and/or drug-adsorbed particles
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9358033B2 (en) * 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
DK1762259T3 (da) 2005-09-12 2011-01-03 Unomedical As Indføringsindretning til infusionssæt med en første og en anden fjederenhed
JP2009507576A (ja) * 2005-09-12 2009-02-26 アルザ コーポレイション 被膜可能な経皮送達微小突起アセンブリ
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070066934A1 (en) * 2005-09-19 2007-03-22 Transport Pharmaceuticals, Inc. Electrokinetic delivery system and methods therefor
RU2008116614A (ru) * 2005-09-26 2009-11-10 Конинклейке Филипс Электроникс Н.В. (Nl) Отбор проб вещества и/или доставка вещества через кожу
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US20070083185A1 (en) * 2005-09-30 2007-04-12 Darrick Carter Iontophoretic device and method of delivery of active agents to biological interface
US8801631B2 (en) 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
US8880138B2 (en) 2005-09-30 2014-11-04 Abbott Diabetes Care Inc. Device for channeling fluid and methods of use
JP2009509634A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 官能基化マイクロニードル経皮薬剤送達システム、装置及び方法
US8382681B2 (en) 2005-09-30 2013-02-26 Intuity Medical, Inc. Fully integrated wearable or handheld monitor
US20070083147A1 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Iontophoresis apparatus and method to deliver antibiotics to biological interfaces
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US7842008B2 (en) 2005-11-21 2010-11-30 Becton, Dickinson And Company Intradermal delivery device
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
WO2007075614A1 (fr) * 2005-12-21 2007-07-05 3M Innovative Properties Company Dispositifs a microaiguilles
WO2007076458A1 (fr) * 2005-12-21 2007-07-05 Primegen Biotech Llc Puce a micro-injecteur
NZ569168A (en) 2005-12-22 2012-02-24 Glaxosmithkline Biolog Sa Streptococcus pneumoniae polysaccharide conjugate vaccine comprising 19F-DT conjugate
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
CA2634335A1 (fr) 2005-12-23 2007-06-28 Unomedical A/S Appareil pour administration
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
ES2551305T3 (es) 2005-12-28 2015-11-17 Alza Corporation Formulaciones terapéuticas estables
EP1968432A4 (fr) 2005-12-28 2009-10-21 Abbott Diabetes Care Inc Insertion d'un dispositif medical
US7658728B2 (en) * 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
US7736310B2 (en) 2006-01-30 2010-06-15 Abbott Diabetes Care Inc. On-body medical device securement
ATE532553T1 (de) 2006-02-10 2011-11-15 Hisamitsu Pharmaceutical Co Transdermales arzneiverabreichungsgerät mit mikronadeln
JP5038334B2 (ja) 2006-02-28 2012-10-03 ウノメディカル アクティーゼルスカブ 注入部品のための挿入具及び針保護具を備えた注入部品
US7885698B2 (en) * 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US7826879B2 (en) 2006-02-28 2010-11-02 Abbott Diabetes Care Inc. Analyte sensors and methods of use
WO2007106597A2 (fr) * 2006-03-15 2007-09-20 Alza Corporation Appareil et procede d'administration transdermique d'agents hormonaux parathyroidiens destines a traiter ou prevenir l'osteopenie
US20100049021A1 (en) * 2006-03-28 2010-02-25 Jina Arvind N Devices, systems, methods and tools for continuous analyte monitoring
US20080154107A1 (en) * 2006-12-20 2008-06-26 Jina Arvind N Device, systems, methods and tools for continuous glucose monitoring
US20090131778A1 (en) * 2006-03-28 2009-05-21 Jina Arvind N Devices, systems, methods and tools for continuous glucose monitoring
SG170090A1 (en) 2006-03-30 2011-04-29 Glaxosmithkline Biolog Sa Immunogenic composition
US8224415B2 (en) 2009-01-29 2012-07-17 Abbott Diabetes Care Inc. Method and device for providing offset model based calibration for analyte sensor
US8478557B2 (en) 2009-07-31 2013-07-02 Abbott Diabetes Care Inc. Method and apparatus for providing analyte monitoring system calibration accuracy
US8219173B2 (en) 2008-09-30 2012-07-10 Abbott Diabetes Care Inc. Optimizing analyte sensor calibration
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US9675290B2 (en) 2012-10-30 2017-06-13 Abbott Diabetes Care Inc. Sensitivity calibration of in vivo sensors used to measure analyte concentration
US7618369B2 (en) 2006-10-02 2009-11-17 Abbott Diabetes Care Inc. Method and system for dynamically updating calibration parameters for an analyte sensor
US8374668B1 (en) 2007-10-23 2013-02-12 Abbott Diabetes Care Inc. Analyte sensor with lag compensation
US9392969B2 (en) 2008-08-31 2016-07-19 Abbott Diabetes Care Inc. Closed loop control and signal attenuation detection
US8473022B2 (en) 2008-01-31 2013-06-25 Abbott Diabetes Care Inc. Analyte sensor with time lag compensation
US8140312B2 (en) 2007-05-14 2012-03-20 Abbott Diabetes Care Inc. Method and system for determining analyte levels
US8583205B2 (en) 2008-03-28 2013-11-12 Abbott Diabetes Care Inc. Analyte sensor calibration management
US7801582B2 (en) 2006-03-31 2010-09-21 Abbott Diabetes Care Inc. Analyte monitoring and management system and methods therefor
US8346335B2 (en) 2008-03-28 2013-01-01 Abbott Diabetes Care Inc. Analyte sensor calibration management
US7653425B2 (en) 2006-08-09 2010-01-26 Abbott Diabetes Care Inc. Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US7630748B2 (en) 2006-10-25 2009-12-08 Abbott Diabetes Care Inc. Method and system for providing analyte monitoring
US20090099502A1 (en) * 2006-04-07 2009-04-16 Hisamitsu Pharmaceutical Co., Inc. Microneedle Device And Transdermal Administration Device Provided With Microneedles
WO2007124411A1 (fr) * 2006-04-20 2007-11-01 3M Innovative Properties Company Dispositif de pose d'une barrette de microaiguilles
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
WO2007127808A2 (fr) * 2006-04-25 2007-11-08 Alza Corporation Application d'un réseau de microsaillies, les microsaillies étant façonnées pour accroître la charge médicamenteuse
WO2007127815A2 (fr) * 2006-04-25 2007-11-08 Alza Corporation Application d'un réseau de microprotubérances muni d'éléments de microprotubérances multicouches pour charge de médicament élevée
AU2007256561B2 (en) 2006-06-07 2012-07-19 Unomedical A/S Inserter for transcutaneous sensor
WO2007143225A2 (fr) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Système et procédé de surveillance d'un analyte
CN101489604B (zh) 2006-06-09 2012-05-23 优诺医疗有限公司 安装垫
US20080015494A1 (en) * 2006-07-11 2008-01-17 Microchips, Inc. Multi-reservoir pump device for dialysis, biosensing, or delivery of substances
KR20090037492A (ko) 2006-08-02 2009-04-15 우노메디컬 에이/에스 캐뉼라와 약물공급장치
EP2073888A4 (fr) * 2006-08-28 2011-01-19 Agency Science Tech & Res Micro-aiguilles et procédés pour fabriquer des micro-aiguilles
JP2010502270A (ja) * 2006-08-29 2010-01-28 アルザ・コーポレーシヨン 水和可能な貯蔵器の水和測定付きの薬品電気輸送
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
US8192474B2 (en) 2006-09-26 2012-06-05 Zeltiq Aesthetics, Inc. Tissue treatment methods
US9132031B2 (en) 2006-09-26 2015-09-15 Zeltiq Aesthetics, Inc. Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
US20080077201A1 (en) 2006-09-26 2008-03-27 Juniper Medical, Inc. Cooling devices with flexible sensors
US7831287B2 (en) * 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
PL2086582T3 (pl) 2006-10-12 2013-04-30 Glaxosmithkline Biologicals Sa Kompozycja zawierająca adiuwant w postaci emulsji typu olej w wodzie
DK2086582T3 (da) 2006-10-12 2013-02-04 Glaxosmithkline Biolog Sa Vaccine omfattende en olie-i-vand-emulsionsadjuvans
BRPI0718119A2 (pt) 2006-10-26 2014-07-08 Abbott Diabetes Care Inc Métodos, sistemas e programas de computador para a detecção em tempo real do declínio de sensibilidade em sensores de analito
EP1917990A1 (fr) 2006-10-31 2008-05-07 Unomedical A/S Ensemble de perfusion
US7785301B2 (en) * 2006-11-28 2010-08-31 Vadim V Yuzhakov Tissue conforming microneedle array and patch for transdermal drug delivery or biological fluid collection
WO2008067409A2 (fr) * 2006-11-28 2008-06-05 Polyplus Battery Company Électrodes au lithium protégées pour l'administration de médicament par électrotransport
US20080147186A1 (en) * 2006-12-14 2008-06-19 Joshi Ashok V Electrochemical Implant For Delivering Beneficial Agents
EP2121111B1 (fr) * 2007-01-22 2018-03-14 Corium International, Inc. Applicateurs pour micro-aiguilles
ES2622555T3 (es) * 2007-01-22 2017-07-06 Nitto Denko Corporation Sistema de administración transdérmica de permeante
US20080199894A1 (en) 2007-02-15 2008-08-21 Abbott Diabetes Care, Inc. Device and method for automatic data acquisition and/or detection
US8121857B2 (en) 2007-02-15 2012-02-21 Abbott Diabetes Care Inc. Device and method for automatic data acquisition and/or detection
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US20080234562A1 (en) * 2007-03-19 2008-09-25 Jina Arvind N Continuous analyte monitor with multi-point self-calibration
WO2008130898A1 (fr) 2007-04-14 2008-10-30 Abbott Diabetes Care, Inc. Procédé et appareil pour réaliser le traitement et la commande de données dans un système de communication médical
WO2008130895A2 (fr) 2007-04-14 2008-10-30 Abbott Diabetes Care, Inc. Procédé et appareil pour assurer une amplification de signal dynamique à étapes multiples dans un dispositif médical
WO2008130897A2 (fr) 2007-04-14 2008-10-30 Abbott Diabetes Care, Inc. Procédé et appareil pour réaliser le traitement et la commande de données dans un système de communication médical
WO2008128210A1 (fr) 2007-04-14 2008-10-23 Abbott Diabetes Care, Inc. Procédé et appareil pour réaliser le traitement et la commande de données dans un système de communication médical
US10111608B2 (en) 2007-04-14 2018-10-30 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
ES2461090T3 (es) 2007-04-14 2014-05-16 Abbott Diabetes Care Inc. Procedimiento y aparato para proporcionar tratamiento y control de datos en un sistema de comunicación médica
US8911749B2 (en) * 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2008130587A2 (fr) 2007-04-16 2008-10-30 Corium International, Inc. Réseaux de micro-aiguilles coulées dans un solvant contenant un actif
US8439861B2 (en) 2007-04-24 2013-05-14 Velcro Industries B.V. Skin penetrating touch fasteners
US8747872B2 (en) 2007-05-02 2014-06-10 The Regents Of The University Of Michigan Nanoemulsion therapeutic compositions and methods of using the same
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8260558B2 (en) 2007-05-14 2012-09-04 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8560038B2 (en) 2007-05-14 2013-10-15 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8600681B2 (en) 2007-05-14 2013-12-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8444560B2 (en) 2007-05-14 2013-05-21 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8239166B2 (en) 2007-05-14 2012-08-07 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US7996158B2 (en) 2007-05-14 2011-08-09 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8103471B2 (en) 2007-05-14 2012-01-24 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US10002233B2 (en) 2007-05-14 2018-06-19 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US9125548B2 (en) 2007-05-14 2015-09-08 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US20080287839A1 (en) 2007-05-18 2008-11-20 Juniper Medical, Inc. Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US20080312518A1 (en) * 2007-06-14 2008-12-18 Arkal Medical, Inc On-demand analyte monitor and method of use
JP2010530266A (ja) 2007-06-20 2010-09-09 ウノメディカル アクティーゼルスカブ カテーテル並びにカテーテルの製造方法及び装置
JP2010531169A (ja) 2007-06-21 2010-09-24 アボット ダイアベティス ケア インコーポレイテッド 健康監視装置
WO2008157820A1 (fr) 2007-06-21 2008-12-24 Abbott Diabetes Care, Inc. Dispositifs et procédés de gestion de la santé
KR101579947B1 (ko) 2007-06-26 2015-12-28 글락소스미스클라인 바이오로지칼즈 에스.에이. 스트렙토코쿠스 뉴모니애 캡슐 다당류 컨쥬게이트를 포함하는 백신
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
US20090005824A1 (en) * 2007-06-29 2009-01-01 Polyplus Battery Company Electrotransport devices, methods and drug electrode assemblies
US8430850B2 (en) 2007-07-03 2013-04-30 Unomedical A/S Inserter having bistable equilibrium states
KR20100062991A (ko) 2007-07-10 2010-06-10 우노메디컬 에이/에스 두 개의 스프링을 갖는 인서터
US8523927B2 (en) 2007-07-13 2013-09-03 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
US8246588B2 (en) 2007-07-18 2012-08-21 Unomedical A/S Insertion device with pivoting action
US8834366B2 (en) 2007-07-31 2014-09-16 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor calibration
US7768386B2 (en) * 2007-07-31 2010-08-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
KR101522747B1 (ko) * 2007-08-06 2015-05-26 알레간 인코포레이티드 데스모프레신 약물 전달을 위한 방법 및 장치
AU2008283896A1 (en) 2007-08-06 2009-02-12 Transderm, Inc. Microneedle arrays formed from polymer films
EP3488833A1 (fr) 2007-08-21 2019-05-29 Zeltiq Aesthetics, Inc. Surveillance du refroidissement de cellules riches en lipides sous-cutanés, tel que le refroidissement du tissu adipeux
US20090069740A1 (en) * 2007-09-07 2009-03-12 Polyplus Battery Company Protected donor electrodes for electro-transport drug delivery
ES2612061T3 (es) * 2007-09-28 2017-05-11 The Queen's University Of Belfast Dispositivo y método de suministro
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
US20090099427A1 (en) * 2007-10-12 2009-04-16 Arkal Medical, Inc. Microneedle array with diverse needle configurations
US8216138B1 (en) 2007-10-23 2012-07-10 Abbott Diabetes Care Inc. Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration
US8377031B2 (en) 2007-10-23 2013-02-19 Abbott Diabetes Care Inc. Closed loop control system with safety parameters and methods
US8409093B2 (en) 2007-10-23 2013-04-02 Abbott Diabetes Care Inc. Assessing measures of glycemic variability
US20090164239A1 (en) 2007-12-19 2009-06-25 Abbott Diabetes Care, Inc. Dynamic Display Of Glucose Information
US9220678B2 (en) 2007-12-24 2015-12-29 The University Of Queensland Coating method
US7766846B2 (en) 2008-01-28 2010-08-03 Roche Diagnostics Operations, Inc. Rapid blood expression and sampling
CN102007066B (zh) 2008-02-07 2013-06-26 昆士兰大学 贴片制造
US10898643B2 (en) 2008-02-13 2021-01-26 Unomedical A/S Sealing between a cannula part and a fluid path
US8157747B2 (en) * 2008-02-15 2012-04-17 Lary Research & Development, Llc Single-use indicator for a surgical instrument and a surgical instrument incorporating same
CA2715667A1 (fr) 2008-02-20 2009-08-27 Unomedical A/S Dispositif d'insertion munie d'une piece mobile dans le sens horizontal
US20110251602A1 (en) 2008-04-01 2011-10-13 The General Hospital Corporation Method and apparatus for tissue expansion
US20090259176A1 (en) * 2008-04-09 2009-10-15 Los Gatos Research, Inc. Transdermal patch system
EP2262543B1 (fr) 2008-04-10 2015-07-08 Abbott Diabetes Care Inc. Procédé et système pour stériliser un détecteur d'analyte
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
ES2678694T3 (es) 2008-04-16 2018-08-16 Glaxosmithkline Biologicals Sa Vacuna
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
US9381680B2 (en) * 2008-05-21 2016-07-05 Theraject, Inc. Method of manufacturing solid solution perforator patches and uses thereof
LT2712622T (lt) * 2008-05-21 2016-09-26 Ferring B.V. Burnoje disperguojamas desmopresinas, skirtas nikturijos netrikdomo miego pirminio periodo pailginimui
EP2294415A4 (fr) 2008-05-23 2011-10-05 Univ Queensland Détection de substances à analyser par un timbre à micro-aiguilles avec des réactifs sélectifs
US8591410B2 (en) 2008-05-30 2013-11-26 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
CA2725264C (fr) 2008-05-30 2017-06-20 Intuity Medical, Inc. Dispositif de prelevement de liquide organique et interface de site de prelevement
US7826382B2 (en) 2008-05-30 2010-11-02 Abbott Diabetes Care Inc. Close proximity communication device and methods
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
EP2329035A2 (fr) * 2008-06-04 2011-06-08 Seventh Sense Biosystems, Inc. Compositions et procédés pour un diagnostic rapide en une seule étape
CA2726071C (fr) 2008-06-06 2024-01-02 Intuity Medical, Inc. Appareil de mesure de glycemie
JP5642066B2 (ja) 2008-06-06 2014-12-17 インテュイティ メディカル インコーポレイテッド 体液の試料内に含まれている検体の存在または濃度を決定する検定を行う方法および装置
CN105902482A (zh) 2008-06-25 2016-08-31 Fe3医学有限公司 用于经皮递送治疗有效量的铁的贴片和方法
US8876755B2 (en) 2008-07-14 2014-11-04 Abbott Diabetes Care Inc. Closed loop control system interface and methods
US8202531B2 (en) * 2008-07-23 2012-06-19 Warsaw Orthopedic, Inc. Drug depots having one or more anchoring members
EP2149957B1 (fr) * 2008-07-30 2017-06-14 Harman Becker Automotive Systems GmbH Distribution électrique basée sur la priorité
US8734422B2 (en) 2008-08-31 2014-05-27 Abbott Diabetes Care Inc. Closed loop control with improved alarm functions
US9943644B2 (en) 2008-08-31 2018-04-17 Abbott Diabetes Care Inc. Closed loop control with reference measurement and methods thereof
US20100057040A1 (en) 2008-08-31 2010-03-04 Abbott Diabetes Care, Inc. Robust Closed Loop Control And Methods
US8622988B2 (en) 2008-08-31 2014-01-07 Abbott Diabetes Care Inc. Variable rate closed loop control and methods
US10383985B2 (en) * 2008-09-09 2019-08-20 Oxyband Technologies, Inc. Methods and apparatus for charging and evacuating a diffusion dressing
JP5722782B2 (ja) 2008-09-26 2015-05-27 ナノバイオ コーポレーション ナノエマルジョン治療用組成物及びその使用方法
US8986208B2 (en) 2008-09-30 2015-03-24 Abbott Diabetes Care Inc. Analyte sensor sensitivity attenuation mitigation
US9326707B2 (en) 2008-11-10 2016-05-03 Abbott Diabetes Care Inc. Alarm characterization for analyte monitoring devices and systems
CA2743904A1 (fr) 2008-11-17 2010-05-20 The Regents Of The University Of Michigan Compositions de vaccins contre le cancer et leurs methodes d'utilisation
US8603073B2 (en) 2008-12-17 2013-12-10 Zeltiq Aesthetics, Inc. Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells
PL2384217T3 (pl) 2008-12-22 2021-08-02 Unomedical A/S Urządzenie medyczne zawierające podkładkę samoprzylepną
MX2011007137A (es) * 2008-12-30 2011-12-06 Nupathe Inc Control electronico de un sistema de suministro de farmaco.
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US9119578B2 (en) 2011-04-29 2015-09-01 Seventh Sense Biosystems, Inc. Plasma or serum production and removal of fluids under reduced pressure
EP3566649B1 (fr) 2009-03-02 2023-06-07 YourBio Health, Inc. Dispositifs de prélèvement de sang
US20110105951A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin
US8781576B2 (en) * 2009-03-17 2014-07-15 Cardiothrive, Inc. Device and method for reducing patient transthoracic impedance for the purpose of delivering a therapeutic current
CN102427851B (zh) 2009-03-17 2015-04-15 卡迪欧思莱夫公司 体外除颤器
US8617487B2 (en) 2009-03-25 2013-12-31 Venture Lending & Leasing Vi, Inc. Saliva sample collection systems
CN101829396B (zh) * 2009-03-27 2013-01-30 清华大学 微针阵列芯片及利用其的经皮给药贴剂及其制备方法
US8497777B2 (en) 2009-04-15 2013-07-30 Abbott Diabetes Care Inc. Analyte monitoring system having an alert
JP5820805B2 (ja) * 2009-04-24 2015-11-24 コリウム インターナショナル， インコーポレイテッド マイクロプロジェクションのアレイの製造のためのプロセス
US8821945B2 (en) * 2009-04-25 2014-09-02 Fe3 Medical, Inc. Method for transdermal iontophoretic delivery of chelated agents
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
GB2469839B (en) * 2009-04-29 2014-09-10 Cook Medical Technologies Llc Medical instrument
US8368556B2 (en) 2009-04-29 2013-02-05 Abbott Diabetes Care Inc. Method and system for providing data communication in continuous glucose monitoring and management system
EP2425209A4 (fr) 2009-04-29 2013-01-09 Abbott Diabetes Care Inc Procédé et système pour fournir un étalonnage de détecteur d'analyte en temps réel avec remplissage rétrospectif
BRPI1014623B1 (pt) 2009-04-30 2020-01-07 Zeltiq Aesthetics, Inc. Sistema para tratamento de celulas subcutâneas ricas em lipídeos em uma área alvo
WO2010138856A1 (fr) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Systèmes d'antenne de dispositif médical comportant des configurations d'antenne externe
EP2440116B1 (fr) * 2009-06-10 2018-02-28 Medtronic, Inc. Dispositif et méthode de surveillance de la saturation en oxygène absolue et de la concentration d'hémoglobine dans un tissu
EP2442827B1 (fr) 2009-06-16 2016-01-06 The Regents of the University of Michigan Vaccins en nano-émulsion
US8613892B2 (en) 2009-06-30 2013-12-24 Abbott Diabetes Care Inc. Analyte meter with a moveable head and methods of using the same
EP4309580A3 (fr) 2009-07-23 2024-02-28 Abbott Diabetes Care Inc. Système de mesure d'analytes continue
AU2010277755A1 (en) 2009-07-30 2012-02-02 Unomedical A/S Inserter device with horizontal moving part
GB0913681D0 (en) 2009-08-05 2009-09-16 Glaxosmithkline Biolog Sa Immunogenic composition
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
RU2012108579A (ru) 2009-08-07 2013-09-20 Уномедикал А/С Доставочное устройство с датчиком и одной или несколькими канюлями
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US8514086B2 (en) 2009-08-31 2013-08-20 Abbott Diabetes Care Inc. Displays for a medical device
WO2011026147A1 (fr) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Dispositif et procédés de traitement de signal d'analyte
EP3001194B1 (fr) 2009-08-31 2019-04-17 Abbott Diabetes Care, Inc. Dispositifs médicaux et procédés
EP2473099A4 (fr) 2009-08-31 2015-01-14 Abbott Diabetes Care Inc Système de surveillance de substance à analyser et procédés de gestion de l'énergie et du bruit
US20130018279A1 (en) * 2009-09-01 2013-01-17 Pathway Genomics "blood sample collection apparatus and kits"
EP2482720A4 (fr) 2009-09-29 2014-04-23 Abbott Diabetes Care Inc Procédé et appareil de fourniture de fonction de notification dans des systèmes de surveillance de substance à analyser
EP2493535A2 (fr) * 2009-10-30 2012-09-05 Seventh Sense Biosystems, Inc. Systèmes et procédés pour application à la peau et commande de l'activation, de la délivrance et/ou de la perception de ceux-ci
US8185181B2 (en) 2009-10-30 2012-05-22 Abbott Diabetes Care Inc. Method and apparatus for detecting false hypoglycemic conditions
WO2011065972A2 (fr) * 2009-11-24 2011-06-03 Seventh Sense Biosystems, Inc. Technique d'auto-prélèvement d'échantillons par le patient
US8919605B2 (en) 2009-11-30 2014-12-30 Intuity Medical, Inc. Calibration material delivery devices and methods
EP2523603A2 (fr) * 2010-01-13 2012-11-21 Seventh Sense Biosystems, Inc. Interfaces pour dispositifs d'échantillonnage
WO2011088214A2 (fr) * 2010-01-13 2011-07-21 Seventh Sense Biosystems, Inc. Administration et/ou enlèvement rapide de fluides
US9314368B2 (en) 2010-01-25 2016-04-19 Zeltiq Aesthetics, Inc. Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associates devices, systems and methods
WO2011094573A1 (fr) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Systèmes et procédés de surveillance ou de rétroaction
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
GB201003920D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
GB201003922D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Conjugation process
WO2011112753A1 (fr) 2010-03-10 2011-09-15 Abbott Diabetes Care Inc. Systèmes, dispositifs et procédés pour le contrôle de niveaux de glucose
CA3135001A1 (fr) 2010-03-24 2011-09-29 Abbott Diabetes Care Inc. Appareils d'insertion de dispositifs medicaux et procedes d'insertion et d'utilisation de dispositifs medicaux
BR112012024635A2 (pt) 2010-03-30 2017-08-08 Unomedical As dispositivo médico
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2011137221A1 (fr) * 2010-04-28 2011-11-03 Inovio Pharmaceuticals, Inc. Dispositif d'électroporation à usage oral, appliqué à une muqueuse, et son utilisation
US9687641B2 (en) 2010-05-04 2017-06-27 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US8658603B2 (en) 2010-06-16 2014-02-25 The Regents Of The University Of Michigan Compositions and methods for inducing an immune response
US8635046B2 (en) 2010-06-23 2014-01-21 Abbott Diabetes Care Inc. Method and system for evaluating analyte sensor response characteristics
WO2011163347A2 (fr) 2010-06-23 2011-12-29 Seventh Sense Biosystems, Inc. Dispositifs et procédés d'échantillonnage entraînant peu de douleur
WO2011162823A1 (fr) 2010-06-25 2011-12-29 Intuity Medical, Inc. Systèmes et procédés de surveillance de substance à analyser
US10092229B2 (en) 2010-06-29 2018-10-09 Abbott Diabetes Care Inc. Calibration of analyte measurement system
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US9943673B2 (en) 2010-07-14 2018-04-17 Vaxxas Pty Limited Patch applying apparatus
JP2013538069A (ja) 2010-07-16 2013-10-10 セブンス センス バイオシステムズ，インコーポレーテッド 流体移動デバイスのための低圧環境
US8676338B2 (en) 2010-07-20 2014-03-18 Zeltiq Aesthetics, Inc. Combined modality treatment systems, methods and apparatus for body contouring applications
US20130158482A1 (en) * 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US20120041338A1 (en) * 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Clinical and/or consumer techniques and devices
EP2433663A1 (fr) 2010-09-27 2012-03-28 Unomedical A/S Système d'insertion
EP2436412A1 (fr) 2010-10-04 2012-04-04 Unomedical A/S Canule d'arroseur
EP2624745A4 (fr) 2010-10-07 2018-05-23 Abbott Diabetes Care, Inc. Dispositifs et procédés de surveillance d'analyte
US10024510B2 (en) * 2010-10-26 2018-07-17 Steven G. Hammond Flexible light emitting diode lighting process and assembly
US8808202B2 (en) 2010-11-09 2014-08-19 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
US10722395B2 (en) 2011-01-25 2020-07-28 Zeltiq Aesthetics, Inc. Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells
CN103619255B (zh) 2011-02-28 2016-11-02 雅培糖尿病护理公司 与分析物监测装置关联的装置、系统和方法以及结合了它们的装置
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
GB201103836D0 (en) 2011-03-07 2011-04-20 Glaxosmithkline Biolog Sa Conjugation process
JP6141827B2 (ja) 2011-04-15 2017-06-07 デックスコム・インコーポレーテッド 検体を測定するシステムの作動方法及び該方法を実施するべく構成されたセンサシステム
KR102237667B1 (ko) 2011-04-29 2021-04-12 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
WO2012149155A1 (fr) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systèmes et procédés pour collecter un fluide d'un sujet
MX339058B (es) 2011-05-17 2016-05-09 Glaxosmithkline Biolog Sa Vacuna contra streptococcus pneumoniae.
JP6223337B2 (ja) 2011-08-03 2017-11-08 インテュイティ メディカル インコーポレイテッド 体液抽出測定器
US11197689B2 (en) 2011-10-05 2021-12-14 Unomedical A/S Inserter for simultaneous insertion of multiple transcutaneous parts
AU2012323392A1 (en) 2011-10-12 2014-04-24 3M Innovative Properties Company Integrated microneedle array delivery system
EP4233839A3 (fr) 2011-10-12 2023-09-27 Vaxxas Pty Limited Dispositif de distribution
US8585721B2 (en) * 2011-10-12 2013-11-19 Covidien Lp Mesh fixation system
EP2583715A1 (fr) 2011-10-19 2013-04-24 Unomedical A/S Système de tube de perfusion et procédé de fabrication
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US9069536B2 (en) 2011-10-31 2015-06-30 Abbott Diabetes Care Inc. Electronic devices having integrated reset systems and methods thereof
WO2013066849A1 (fr) 2011-10-31 2013-05-10 Abbott Diabetes Care Inc. Mécanisme de prévention de fausse alarme de seuil de glucose à risque variable basé sur un modèle
AU2012335830B2 (en) 2011-11-07 2017-05-04 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US9317656B2 (en) 2011-11-23 2016-04-19 Abbott Diabetes Care Inc. Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof
US8710993B2 (en) 2011-11-23 2014-04-29 Abbott Diabetes Care Inc. Mitigating single point failure of devices in an analyte monitoring system and methods thereof
WO2013078426A2 (fr) 2011-11-25 2013-05-30 Abbott Diabetes Care Inc. Système de surveillance des analytes et ses procédés d'utilisation
CA3118810A1 (fr) 2011-12-11 2013-06-20 Abbott Diabetes Care Inc. Dispositifs detecteurs d'analytes, connexions, et procedes
KR102101522B1 (ko) * 2012-06-12 2020-04-16 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들·시트
EP2890297B1 (fr) 2012-08-30 2018-04-11 Abbott Diabetes Care, Inc. Détection de pertes d'information dans des données de surveillance continue d'analyte lors d'excursions des données
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
WO2014052136A1 (fr) 2012-09-26 2014-04-03 Abbott Diabetes Care Inc. Procédé et appareil d'amélioration de correction de retard pendant une mesure in vivo de concentration de substance à analyser avec des données de variabilité et de plage de concentration de substance à analyser
US20160128947A1 (en) * 2012-10-22 2016-05-12 Stc. Unm Bioadhesive films for local and/or systemic delivery
BR112015009229B1 (pt) 2012-10-24 2021-07-20 Platelet Targeted Therapeutics, Llc Composição tendo como alvo a expressão de genes para plaquetas, uso de uma célula tronco compreendendo a referida composição para tratar hemofilia e método in vitro ou ex vivo para gerar uma célula tronco modificada
MX2015008157A (es) 2012-12-21 2016-02-22 Corium Int Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
AU2014219240B2 (en) 2013-02-20 2018-12-20 Cytrellis Biosystems, Inc. Methods and devices for skin tightening
BR112015022253B1 (pt) 2013-03-12 2022-03-15 Corium, Inc Aplicador de microprojeções
US9545523B2 (en) 2013-03-14 2017-01-17 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue
US9844460B2 (en) 2013-03-14 2017-12-19 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US9474475B1 (en) 2013-03-15 2016-10-25 Abbott Diabetes Care Inc. Multi-rate analyte sensor data collection with sample rate configurable signal processing
US10433773B1 (en) 2013-03-15 2019-10-08 Abbott Diabetes Care Inc. Noise rejection methods and apparatus for sparsely sampled analyte sensor data
ES2761580T3 (es) 2013-03-15 2020-05-20 Corium Inc Micromatrices para suministro de agente terapéutico, métodos de uso y métodos de fabricación
CA2903459C (fr) 2013-03-15 2024-02-20 Corium International, Inc. Applicateurs de microprojection d'impacts multiples et procedes d'utilisation
MX2015012433A (es) 2013-03-15 2016-02-03 Corium Int Inc Matriz de microestructura para suministro de agentes activos.
WO2014152034A1 (fr) 2013-03-15 2014-09-25 Abbott Diabetes Care Inc. Détection de défaut de capteur utilisant une comparaison de structures de données de capteur d'analyte
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
US9833630B2 (en) 2013-06-14 2017-12-05 Cardiothrive, Inc. Biphasic or multiphasic pulse waveform and method
US10279189B2 (en) 2013-06-14 2019-05-07 Cardiothrive, Inc. Wearable multiphasic cardioverter defibrillator system and method
US10149973B2 (en) 2013-06-14 2018-12-11 Cardiothrive, Inc. Multipart non-uniform patient contact interface and method of use
US9907970B2 (en) 2013-06-14 2018-03-06 Cardiothrive, Inc. Therapeutic system and method using biphasic or multiphasic pulse waveform
US9656094B2 (en) 2013-06-14 2017-05-23 Cardiothrive, Inc. Biphasic or multiphasic pulse generator and method
US9616243B2 (en) 2013-06-14 2017-04-11 Cardiothrive, Inc. Dynamically adjustable multiphasic defibrillator pulse system and method
CA2912283A1 (fr) 2013-06-21 2014-12-21 Intuity Medical, Inc. Systeme de surveillance d'analyte a retroaction audible
EP3027263A1 (fr) 2013-07-30 2016-06-08 ZP Opco, Inc. Applicateur extra-plat de tampon de micro-aiguilles
WO2015021434A2 (fr) 2013-08-09 2015-02-12 Cytrellis Biosystems, Inc. Procédés et appareils pour le traitement de la peau à l'aide d'une ablation de tissu non thermique
KR20160046887A (ko) 2013-08-27 2016-04-29 헤일로우 뉴로 아이엔씨. 전기 자극을 사용자에게 제공하기 위한 방법 및 시스템
US9782585B2 (en) 2013-08-27 2017-10-10 Halo Neuro, Inc. Method and system for providing electrical stimulation to a user
WO2015031510A1 (fr) 2013-08-27 2015-03-05 Halo Neuro, Inc. Système d'électrode pour stimulation électrique
US9486618B2 (en) 2013-08-27 2016-11-08 Halo Neuro, Inc. Electrode system for electrical stimulation
EP3042690B1 (fr) * 2013-09-06 2021-04-14 Hisamitsu Pharmaceutical Co., Inc. Feuille à micro-aiguilles
DE102013219432A1 (de) * 2013-09-26 2015-03-26 Peter Röhr Blutentnahmevorrichtung und Verfahren zum Entnehmen von Blut
CA2928700C (fr) 2013-11-01 2019-01-15 University Of Oslo Variants d'albumine et utilisations de ceux-ci
CA2929126C (fr) 2013-11-13 2020-01-07 University Of Oslo Vesicules de membrane externe et utilisation associees
US11452767B2 (en) 2013-11-15 2022-09-27 Oslo Universitetssykehus Hf CTL peptide epitopes and antigen-specific t cells, methods for their discovery, and uses thereof
US10953143B2 (en) 2013-12-19 2021-03-23 Cytrellis Biosystems, Inc. Methods and devices for manipulating subdermal fat
AU2014374361B9 (en) 2013-12-31 2019-07-04 Abbott Diabetes Care Inc. Self-powered analyte sensor and devices using the same
TWI548395B (zh) * 2014-01-28 2016-09-11 微凸科技股份有限公司 連續經皮微針監測系統
EP3099258B1 (fr) 2014-01-31 2024-02-21 Zeltiq Aesthetics, Inc. Compositions et systèmes de traitement pour le refroidissement amélioré de tissu riche en lipides
US10959631B2 (en) * 2014-02-01 2021-03-30 Biocircuit Technologies, Inc. Neural interfacing device
EP2905047A1 (fr) 2014-02-10 2015-08-12 LTS LOHMANN Therapie-Systeme AG Système de micro-aiguille et son procédé de fabrication
CN106061546A (zh) * 2014-02-10 2016-10-26 Lts勒曼治疗系统股份公司 微针系统及其制造方法
US20170049695A1 (en) * 2014-02-27 2017-02-23 Hisamitsu Pharmaceutical Co., Inc. Microneedle sheet
US10675176B1 (en) 2014-03-19 2020-06-09 Zeltiq Aesthetics, Inc. Treatment systems, devices, and methods for cooling targeted tissue
USD777338S1 (en) 2014-03-20 2017-01-24 Zeltiq Aesthetics, Inc. Cryotherapy applicator for cooling tissue
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
EP3865063A1 (fr) 2014-03-30 2021-08-18 Abbott Diabetes Care, Inc. Procédé et appareil permettant de déterminer le début du repas et le pic prandial dans des systèmes de surveillance d'analyte
US10952891B1 (en) 2014-05-13 2021-03-23 Zeltiq Aesthetics, Inc. Treatment systems with adjustable gap applicators and methods for cooling tissue
US10568759B2 (en) 2014-08-19 2020-02-25 Zeltiq Aesthetics, Inc. Treatment systems, small volume applicators, and methods for treating submental tissue
US10935174B2 (en) 2014-08-19 2021-03-02 Zeltiq Aesthetics, Inc. Stress relief couplings for cryotherapy apparatuses
EP3193828B8 (fr) 2014-08-29 2023-04-05 Corium Pharma Solutions, Inc. Réseaux à microstructures pour l'administration d'agents actifs
WO2016036866A1 (fr) 2014-09-04 2016-03-10 Corium International, Inc. Matrice de microstructures, procédé de production et procédés d'utilisation
CN105455855B (zh) * 2014-09-04 2018-05-25 微凸科技股份有限公司 乳酸量测装置及运动训练调整的方法
WO2016039333A1 (fr) * 2014-09-08 2016-03-17 株式会社かいわ Dispositif de piqûre
JP5967595B2 (ja) * 2014-09-08 2016-08-10 株式会社かいわ 穿刺器具
JP7158853B2 (ja) 2014-10-10 2022-10-24 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 対象における食物アレルギーまたは呼吸器アレルギーを処置するための、かつ上記対象の鼻腔内に投与するための免疫原性組成物
MA40920A (fr) 2014-11-07 2017-09-12 Takeda Vaccines Inc Vaccins de la main, du pied et de la bouche, et procédés de fabrication et d'utilisation de ceux-ci
AR102548A1 (es) 2014-11-07 2017-03-08 Takeda Vaccines Inc Vacunas contra la enfermedad de manos, pies y boca y métodos de fabricación y uso
AU2015346141B2 (en) 2014-11-14 2021-07-22 Cytrellis Biosystems, Inc. Devices and methods for ablation of the skin
JP6906885B2 (ja) 2014-11-14 2021-07-21 ロレアル しわを減少させるためのマイクロニードルシート
TWI679997B (zh) 2014-12-05 2019-12-21 日商久光製藥股份有限公司 微針裝置系統
EP4218892A1 (fr) 2015-02-02 2023-08-02 Vaxxas Pty Limited Applicateur à réseau de microprojections
EP4226936A3 (fr) 2015-03-05 2023-09-27 Northwestern University Virus non neuro-invasifs et leurs utilisations
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
WO2016183493A1 (fr) 2015-05-14 2016-11-17 Abbott Diabetes Care Inc. Instruments d'introduction de dispositifs médicaux compacts et systèmes et procédés associés
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
CN108024765B (zh) 2015-07-10 2021-06-11 雅培糖尿病护理公司 对于生理参数进行动态葡萄糖曲线响应的系统、装置和方法
WO2017045031A1 (fr) 2015-09-18 2017-03-23 Vaxxas Pty Limited Réseaux de micro-saillies comportant des micro-saillies ayant des profils à surface élevée
WO2017070112A1 (fr) 2015-10-19 2017-04-27 Zeltiq Aesthetics, Inc. Systèmes de traitement vasculaire, dispositifs de refroidissement et procédés pour refroidir des structures vasculaires
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
CN108290037B (zh) 2015-10-26 2021-10-08 福禄神经学公司 电极定位系统及方法
EP3399950A1 (fr) 2016-01-07 2018-11-14 Zeltiq Aesthetics, Inc. Adhérence dépendant de la température entre un applicateur et la peau pendant le refroidissement de tissu
WO2017123652A1 (fr) 2016-01-11 2017-07-20 Verndari, Inc. Compositions pour micro-aiguilles et méthodes d'utilisation de celles-ci
EP3408657A4 (fr) * 2016-01-27 2020-01-15 Undercover Colors, Inc. Appareil, système et procédé de détection de substance cible
CN108778409B (zh) 2016-02-08 2022-04-08 哈洛纽罗公司 用于改善电刺激的提供的方法和系统
US10765552B2 (en) 2016-02-18 2020-09-08 Zeltiq Aesthetics, Inc. Cooling cup applicators with contoured heads and liner assemblies
WO2017143345A1 (fr) 2016-02-19 2017-08-24 Zp Opco, Inc. Procédé pour obtenir rapidement des concentrations thérapeutiques de triptans pour le traitement de migraines
KR20180131554A (ko) * 2016-03-01 2018-12-10 키토테크 메디컬 인코포레이티드 상처 봉합을 위한 마이크로 구조-기반 시스템, 장치, 및 방법
EP3435890A1 (fr) 2016-03-29 2019-02-06 Cytrellis Biosystems, Inc. Dispositifs et méthodes de restructuration cosmétique de la peau
US11382790B2 (en) 2016-05-10 2022-07-12 Zeltiq Aesthetics, Inc. Skin freezing systems for treating acne and skin conditions
US10682297B2 (en) 2016-05-10 2020-06-16 Zeltiq Aesthetics, Inc. Liposomes, emulsions, and methods for cryotherapy
US10555831B2 (en) 2016-05-10 2020-02-11 Zeltiq Aesthetics, Inc. Hydrogel substances and methods of cryotherapy
US11173207B2 (en) 2016-05-19 2021-11-16 The Regents Of The University Of Michigan Adjuvant compositions
GB201610599D0 (en) 2016-06-17 2016-08-03 Glaxosmithkline Biologicals Sa Immunogenic Composition
US10485443B2 (en) 2016-06-20 2019-11-26 Halo Neuro, Inc. Electrical interface system
US20190184366A1 (en) * 2016-08-03 2019-06-20 Verndari, Inc. Microarrays and methods
EP3515323A4 (fr) 2016-09-21 2020-06-10 Cytrellis Biosystems, Inc. Dispositifs et méthodes de restructuration cosmétique de la peau
WO2018096396A1 (fr) 2016-11-22 2018-05-31 University Of Oslo Variants d'albumine et leurs utilisations
CN115444410A (zh) 2017-01-23 2022-12-09 雅培糖尿病护理公司 用于插入体内分析物传感器的施加器及组件
WO2018151832A1 (fr) 2017-02-17 2018-08-23 Allergan, Inc. Réseau de micro-aiguilles avec principe actif
US10525255B2 (en) 2017-03-08 2020-01-07 Halo Neuro, Inc. System for electrical stimulation
EP3595515A4 (fr) 2017-03-14 2020-12-30 University of Connecticut Capteur de pression biodégradable
WO2018175489A1 (fr) 2017-03-21 2018-09-27 Abbott Diabetes Care Inc. Méthodes, dispositifs et système pour fournir un diagnostic et une thérapie pour un état diabétique
EP3606760B1 (fr) 2017-03-31 2023-09-27 Vaxxas Pty Limited Dispositif et procédé de revêtement de surfaces
US11278217B2 (en) * 2017-03-31 2022-03-22 RichHealth Technology Corporation Transdermal microneedle array patch
US11076879B2 (en) 2017-04-26 2021-08-03 Zeltiq Aesthetics, Inc. Shallow surface cryotherapy applicators and related technology
AU2018285954A1 (en) 2017-06-13 2019-12-19 Vaxxas Pty Limited Quality control of substrate coatings
CN111065417B (zh) 2017-06-23 2024-04-19 美商艾芬尼维克斯公司 免疫原性组合物
WO2019023757A1 (fr) 2017-08-04 2019-02-07 Vaxxas Pty Limited Actionneur à stockage d'énergie mécanique élevé compact et à force de déclenchement faible pour l'administration de patchs à réseaux de microprojections (prm)
KR20210155817A (ko) 2017-08-23 2021-12-23 조사노 파마 코포레이션 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
WO2019048928A1 (fr) 2017-09-07 2019-03-14 University Of Oslo Molécules de vaccin
US12005112B2 (en) 2017-09-07 2024-06-11 University Of Oslo Vaccine molecules
US10524730B2 (en) * 2017-09-28 2020-01-07 Medtronic Minimed, Inc. Medical devices with microneedle arrays and methods for operating such medical devices
CN107874767B (zh) * 2017-10-12 2020-11-24 杭州博拓生物科技股份有限公司 一种检测样本中被分析物质的装置
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US20190120785A1 (en) 2017-10-24 2019-04-25 Dexcom, Inc. Pre-connected analyte sensors
WO2019090233A2 (fr) 2017-11-03 2019-05-09 Takeda Vaccines, Inc. Procédé pour inactiver le virus zika et pour déterminer la complétude de l'inactivation
JP6920179B2 (ja) 2017-11-15 2021-08-18 新光電気工業株式会社 生体用電極部品及びその製造方法
US10507324B2 (en) 2017-11-17 2019-12-17 Halo Neuro, Inc. System and method for individualizing modulation
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
US10828500B2 (en) 2017-12-22 2020-11-10 Cardiothrive, Inc. External defibrillator
JP7305311B2 (ja) 2018-05-30 2023-07-10 ロレアル マイクロニードルシート
CN112399908B (zh) 2018-06-25 2023-04-07 考里安公司 形成主模、铸模的方法以及制备微结构阵列的方法
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
JP2020002084A (ja) 2018-06-29 2020-01-09 ロレアル マイクロニードルシートを使用する美容方法
JP7335061B2 (ja) 2018-06-29 2023-08-29 ロレアル マイクロニードルシートを使用する美容方法
JP2020018327A (ja) 2018-07-17 2020-02-06 ロレアル マイクロニードルシート
AU2019315940A1 (en) 2018-07-31 2021-03-04 Zeltiq Aesthetics, Inc. Methods, devices, and systems for improving skin characteristics
CN113164069A (zh) * 2018-10-04 2021-07-23 奥尼欧有限公司 具有通知功能的感测器系统以及用于对生物体的温度进行连续无线监测和分析的方法
JP2020099513A (ja) 2018-12-21 2020-07-02 ロレアル マイクロニードルシートを使用するキット及び美容方法
US11826495B2 (en) 2019-03-01 2023-11-28 University Of Connecticut Biodegradable piezoelectric ultrasonic transducer system
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
WO2020264034A1 (fr) * 2019-06-28 2020-12-30 Passport Technologies, Inc. Procédés et systèmes de commande de la distribution d'énergie à des dispositifs à filament
JP2021094146A (ja) 2019-12-16 2021-06-24 ロレアル マイクロニードルシートを使用する美容方法
WO2021168345A1 (fr) 2020-02-19 2021-08-26 Kitotech Medical, Inc. Systèmes à microstructure et méthodes de traitement de la douleur
WO2021168330A1 (fr) * 2020-02-19 2021-08-26 Kitotech Medical, Inc. Microstructures pour fixer des appareils à des tissus
WO2021183626A1 (fr) 2020-03-10 2021-09-16 University Of Connecticut Bandage thérapeutique
FR3113843B1 (fr) 2020-09-07 2024-03-15 Oreal Kit et traitement cosmetique utilisant une feuille de micro-aiguilles
EP4168093A1 (fr) 2020-06-17 2023-04-26 L'oreal Kit et procédé cosmétique utilisant une feuille à micro-aiguilles
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
WO2023039108A1 (fr) 2021-09-08 2023-03-16 Affinivax, Inc. Vaccin anti-coronavirus
WO2023159181A1 (fr) 2022-02-18 2023-08-24 Kitotech Medical, Inc. Agrafes et instruments pour peau profonde à modulation de force
FR3135206A1 (fr) 2022-05-05 2023-11-10 L'oreal Processus cosmétique utilisant une feuille de micro-aiguilles
FR3139007A1 (fr) 2022-08-23 2024-03-01 L'oreal Composition convenant pour des traitements cosmétiques de substance kératineuse

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US946837A (en) * 1908-11-05 1910-01-18 Cordelia L Common Fountain tonic-applicator.
US2619962A (en) * 1948-02-19 1952-12-02 Res Foundation Vaccination appliance
FR1133709A (fr) 1955-10-17 1957-04-01 Dispositif destiné à l'application de nouveaux traitements médicaux
US2893392A (en) 1958-01-08 1959-07-07 American Cyanamid Co Article of manufacture for intracutaneous injections
US3072122A (en) * 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US2974787A (en) * 1960-05-10 1961-03-14 American Cyanamid Co Single use, prepackaged vaccinator
US3322121A (en) * 1965-11-26 1967-05-30 Oscar H Banker Skin-puncturing unit with a collapsible protective cover
CH522395A (fr) * 1968-07-26 1972-05-15 Micromedic Systems Inc Eprouvette destinée à la prise de sang percutanée et digitale
US3675766A (en) * 1970-02-04 1972-07-11 Sol Roy Rosenthal Multiple puncture injector device
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
JPS5029096U (fr) * 1973-07-06 1975-04-02
OA05448A (fr) * 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
US4077407A (en) 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4014334A (en) 1976-02-02 1977-03-29 Alza Corporation Laminated osmotic system for dispensing beneficial agent
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4127118B1 (en) * 1977-03-16 1995-12-19 Alvaro Latorre Method of effecting and enhancing an erection
GB2066376B (en) 1977-11-09 1982-10-20 Emerit Andre A C Source of vacuum and device for creating and maintaining a negative pressure in an enclosure
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4340048A (en) 1981-03-28 1982-07-20 Alza Corporation Self-driven hypodermic injector
US5370675A (en) * 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
US4753651A (en) 1982-08-30 1988-06-28 Alza Corporation Self-driven pump
USH356H (en) * 1985-02-27 1987-11-03 Medtronic, Inc. Epicardial lead having low threshold, low polarization myocardial electrode
SU1296174A1 (ru) * 1985-06-20 1987-03-15 Устиновский Государственный Медицинский Институт Устройство дл электрофореза лекарственных веществ
US4655766A (en) 1985-08-01 1987-04-07 Alza Corporation Fluid imbibing pump with self-regulating skin patch
US4756314A (en) 1985-10-28 1988-07-12 Alza Corporation Sweat collection patch
US4711247A (en) * 1986-04-18 1987-12-08 Henry Fishman Allergy testing method and apparatus
US5080646A (en) 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
DE3735137A1 (de) * 1987-10-16 1989-05-03 Siemens Ag Anordnung zum abgeben von medikamenten bei einem implantierbaren medizinischen geraet
JP2907342B2 (ja) 1988-01-29 1999-06-21 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア イオン滲透非侵襲的サンプリングまたは送出装置
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
US5438984A (en) 1988-09-08 1995-08-08 Sudor Partners Apparatus and method for the collection of analytes on a dermal patch
US5169382A (en) * 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5147296A (en) * 1988-10-03 1992-09-15 Alza Corporation Membrane for electrotransport transdermal drug delivery
US4941517A (en) * 1988-10-20 1990-07-17 Galloway Trust Aseptic fluid transfer apparatus and methods
US5054499A (en) 1989-03-27 1991-10-08 Swierczek Remi D Disposable skin perforator and blood testing device
US5139023A (en) * 1989-06-02 1992-08-18 Theratech Inc. Apparatus and method for noninvasive blood glucose monitoring
EP0429842B1 (fr) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide
US5036861A (en) * 1990-01-11 1991-08-06 Sembrowich Walter L Method and apparatus for non-invasively monitoring plasma glucose levels
US5161532A (en) 1990-04-19 1992-11-10 Teknekron Sensor Development Corporation Integral interstitial fluid sensor
US5300100A (en) * 1990-08-22 1994-04-05 Advanced Warming Systems, Inc. Body warmer
US5158537A (en) * 1990-10-29 1992-10-27 Alza Corporation Iontophoretic delivery device and method of hydrating same
US5156591A (en) 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
SE9101022D0 (sv) 1991-01-09 1991-04-08 Paal Svedman Medicinsk suganordning
US5312456A (en) * 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
US5122114A (en) * 1991-02-01 1992-06-16 Board Of Regents, University Of Texas System Method of using intramedullary catheter
US5231993A (en) 1991-11-20 1993-08-03 Habley Medical Technology Corporation Blood sampler and component tester with guide member
JP2572823Y2 (ja) 1992-02-13 1998-05-25 株式会社アドバンス 簡易採血器
US5484399A (en) * 1992-02-27 1996-01-16 Sloan-Kettering Institute For Cancer Research Process and device to reduce interstitial fluid pressure in tissue
US5309909A (en) * 1992-05-22 1994-05-10 Physio-Control Corporation Combined skin preparation and monitoring electrode
JPH0670987A (ja) * 1992-08-28 1994-03-15 Katsuro Tachibana 薬物投与・体液採取ユニット及び装置
US5300110A (en) * 1992-10-15 1994-04-05 Angeion Corporation Dirk-based epicardial defibrillation electrode
JPH0824680B2 (ja) 1992-10-26 1996-03-13 日本電気株式会社 吸引浸出液採取装置
US5702359A (en) * 1995-06-06 1997-12-30 Genetronics, Inc. Needle electrodes for mediated delivery of drugs and genes
JP2630197B2 (ja) 1993-04-28 1997-07-16 株式会社ニッショー 血液吸出器具
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
JPH084182A (ja) * 1994-06-17 1996-01-09 Nippon Steel Metal Prod Co Ltd フラットデッキプレート用のアンカー部材
DK0766578T3 (da) 1994-06-24 2000-10-23 Cygnus Therapeutic Systems Iontophoretisk prøvetagningsindretning
CA2205444A1 (fr) * 1994-12-09 1996-06-13 Novartis Ag Systeme transdermique
WO1996037155A1 (fr) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Dispositif micromecanique et procede pour ameliorer l'administration percutanee de composes
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
US5571162A (en) * 1995-06-07 1996-11-05 Intermedics, Inc. Transvenous defibrillation lead with side hooks
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
EP0858285A4 (fr) 1995-08-29 2000-05-17 Spectrx Inc Realisation de micropores sur la peau humaine pour l'administration de medicaments et les applications de monitorage
US5682233A (en) 1995-09-08 1997-10-28 Integ, Inc. Interstitial fluid sampler
CA2253549C (fr) * 1996-06-18 2005-10-25 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
ES2200187T3 (es) 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.
WO1998011937A1 (fr) * 1996-09-17 1998-03-26 Deka Products Limited Partnership Systeme d'administration de medicaments par transport
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
KR100561892B1 (ko) * 1997-12-11 2006-03-16 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
AU739616B2 (en) * 1997-12-11 2001-10-18 Alza Corporation Device for enhancing transdermal agent flux
CN1206004C (zh) * 1997-12-11 2005-06-15 阿尔扎有限公司 增强透皮物剂流量的装置
US6022316A (en) * 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
JP4104975B2 (ja) * 2000-10-13 2008-06-18 アルザ・コーポレーシヨン 衝撃適用装置用の微小突起部材保持器
PL360998A1 (en) * 2000-10-13 2004-09-20 Alza Corporation Apparatus and method for piercing skin with microprotrusions
MXPA03003301A (es) * 2000-10-13 2004-12-13 Johnson & Johnson Aplicador de un conjunto de microsalientes mediante impacto.
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
CA2427381A1 (fr) * 2000-10-26 2002-11-28 Alza Corporation Dispositifs d'administration de medicament transdermique avec des microprotrusions enrobees
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
IL158480A0 (en) * 2001-04-20 2004-05-12 Alza Corp Microprojection array having a beneficial agent containing coating
AU2002352978A1 (en) * 2001-11-30 2003-06-17 Alza Corporation Methods and apparatuses for forming microprojection arrays
ES2297056T3 (es) * 2001-12-20 2008-05-01 Alza Corporation Micro-proyecciones para perforacion de la piel que tienen control de la profundidad de perforacion.
EP1554938B1 (fr) * 2002-06-14 2007-07-18 OGAWA & CO., LTD. Inhibiteur de deterioration de gout et inhibiteur de l'odeur de deterioration du citral
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
KR20070001886A (ko) * 2003-10-28 2007-01-04 알자 코포레이션 치료용 펩타이드 및 단백질의 폴리머 컨쥬게이트의 피복된미세돌출부를 통한 전달
US7097631B2 (en) * 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
US20050106209A1 (en) * 2003-11-13 2005-05-19 Mahmoud Ameri Composition and apparatus for transdermal delivery
EP1744683B1 (fr) * 2004-05-13 2016-03-16 Alza Corporation Appareil et procédé pour la délivrance transdermique d'agents à base d'hormone parathyroïde
CA2593112A1 (fr) * 2005-01-21 2006-07-27 Alza Corporation Preparations peptidiques therapeutiques a stabilite accrue
JP5277456B2 (ja) * 2005-01-31 2013-08-28 アルザ コーポレイション 低い変動性を有するコーティングマイクロプロジェクション、及びその生成法
CN101119764A (zh) * 2005-02-16 2008-02-06 阿尔扎公司 具有改善的生物相容性的微突出物阵列
US8374997B2 (en) * 2005-05-20 2013-02-12 Teradota Us, Inc. Application code generation and execution with bypass, logging, user restartability and status functionality
WO2006130826A1 (fr) * 2005-06-02 2006-12-07 Alza Corporation Procede de sterilisation terminale de dispositifs d'administration transdermique
US20070009587A1 (en) * 2005-06-21 2007-01-11 Peter Daddona Method and device for coating a continuous strip of microprojection members

Also Published As

Publication number Publication date
DK0917483T3 (da) 2005-02-07
US6230051B1 (en) 2001-05-08
US20070118070A1 (en) 2007-05-24
PT917484E (pt) 2004-12-31
EP0914178A1 (fr) 1999-05-12
JP3847790B2 (ja) 2006-11-22
JP2007260436A (ja) 2007-10-11
JP2001507947A (ja) 2001-06-19
DK0914178T3 (da) 2003-04-22
ATE234129T1 (de) 2003-03-15
EP0917483A1 (fr) 1999-05-26
DE69730971D1 (de) 2004-11-04
WO1997048442A1 (fr) 1997-12-24
CA2257217C (fr) 2006-03-07
EP0917484A1 (fr) 1999-05-26
AU3572597A (en) 1998-01-07
DE69730973T2 (de) 2005-11-17
DE69719761D1 (de) 2003-04-17
AR008242A1 (es) 1999-12-29
ATE277671T1 (de) 2004-10-15
AU3493397A (en) 1998-01-07
WO1997048440A1 (fr) 1997-12-24
AR012859A2 (es) 2000-11-22
EP0917483B1 (fr) 2004-09-29
DE69730971T2 (de) 2005-11-17
CA2253549A1 (fr) 1997-12-24
EP0917484B1 (fr) 2004-09-29
CA2253471C (fr) 2007-10-30
CA2257217A1 (fr) 1997-12-24
JP2000512529A (ja) 2000-09-26
DE69730973D1 (de) 2004-11-04
US7184826B2 (en) 2007-02-27
DK0917484T3 (da) 2005-02-07
EP0914178B1 (fr) 2003-03-12
CA2253549C (fr) 2005-10-25
JP4012252B2 (ja) 2007-11-21
US20020016562A1 (en) 2002-02-07
ES2195151T3 (es) 2003-12-01
DE69719761T2 (de) 2003-12-18
JP2001505444A (ja) 2001-04-24
ES2230614T3 (es) 2005-05-01
WO1997048441A1 (fr) 1997-12-24
TW349872B (en) 1999-01-11
ATE277670T1 (de) 2004-10-15
PT917483E (pt) 2005-01-31
US6219574B1 (en) 2001-04-17
CA2253471A1 (fr) 1997-12-24
US6537264B1 (en) 2003-03-25
ES2230611T3 (es) 2005-05-01
AU3399197A (en) 1998-01-07

Similar Documents

Publication Publication Date Title
ZA975326B (en) Device and method for enhancing transdermal flux of agents being delivered or sampled.
IL133431A0 (en) Device and method for treatment of dysmenorrhea
GB2319546B (en) Device and method for performing downhole functions
HUP0004105A2 (en) Method and device for sewage treatment
EP1054652A4 (fr) Dispositif et methode de traitement de maux de tete
EP0984727A4 (fr) Procede et dispositif de vascularisation transmyocardique
IL131185A (en) Method and device for solid phase microextraction
EP0827194A4 (fr) Procede et dispositif destine a un traitement
GB2359136B (en) Device and method for alignment
EP1139886A4 (fr) Methode et dispositif favorisant le transport transdermique
EP1065471A4 (fr) Dispositif et procede de navigation
HUP9900997A3 (en) Method and device for heat-treating plaster
EP0853291A4 (fr) Procede et dispositif de traitement de l'information
AU7027098A (en) Method and device for surface treatment
HUP0000975A2 (en) Method and device for induction sealing
EP0716936A3 (fr) Dispositif et méthode de reliure permanente de liasses de papier
GB9809448D0 (en) Treatment device and method
GB9609608D0 (en) Method and device
AUPO355996A0 (en) Apparatus and/or device for concentration
ZA9711548B (en) Ricin inhibitors and methods for use thereof
GB9609607D0 (en) Method and device
HK1023685A1 (en) Method and device for positioning and retaining microbuilding-blocks
LT97082A (en) Method of and device for renovation of quay
AU1168000A (en) Device for supporting and/or guiding objects and method for setting said deviceson said objects
GB9704736D0 (en) Device and method