YU49221B - Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova - Google Patents

Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova

Info

Publication number
YU49221B
YU49221B YU21695A YU21695A YU49221B YU 49221 B YU49221 B YU 49221B YU 21695 A YU21695 A YU 21695A YU 21695 A YU21695 A YU 21695A YU 49221 B YU49221 B YU 49221B
Authority
YU
Yugoslavia
Prior art keywords
carbon atoms
hydrogen atom
heteroatoms
medicines
procedure
Prior art date
Application number
YU21695A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU21695A (sh
Inventor
Constantin Agouridas
Yannick Benedetti
Jean-Francois Chantot
Alexis Denis
Odile Le Martret
Original Assignee
Roussel-Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel-Uclaf filed Critical Roussel-Uclaf
Publication of YU21695A publication Critical patent/YU21695A/sh
Publication of YU49221B publication Critical patent/YU49221B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
YU21695A 1994-04-08 1995-04-05 Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova YU49221B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (2)

Publication Number Publication Date
YU21695A YU21695A (sh) 1997-12-05
YU49221B true YU49221B (sh) 2004-11-25

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
YU21695A YU49221B (sh) 1994-04-08 1995-04-05 Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova

Country Status (49)

Country Link
US (2) US5656607A (cg-RX-API-DMAC7.html)
EP (1) EP0676409B1 (cg-RX-API-DMAC7.html)
JP (1) JP3000023B2 (cg-RX-API-DMAC7.html)
KR (1) KR100317148B1 (cg-RX-API-DMAC7.html)
CN (1) CN1059445C (cg-RX-API-DMAC7.html)
AP (1) AP587A (cg-RX-API-DMAC7.html)
AT (1) ATE234853T1 (cg-RX-API-DMAC7.html)
AU (1) AU684939B2 (cg-RX-API-DMAC7.html)
BG (1) BG61916B1 (cg-RX-API-DMAC7.html)
BR (1) BR9506147A (cg-RX-API-DMAC7.html)
CA (1) CA2164638C (cg-RX-API-DMAC7.html)
CO (1) CO4370097A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ296005B6 (cg-RX-API-DMAC7.html)
DE (1) DE69529934T2 (cg-RX-API-DMAC7.html)
DK (1) DK0676409T3 (cg-RX-API-DMAC7.html)
DZ (1) DZ1869A1 (cg-RX-API-DMAC7.html)
EE (1) EE04498B1 (cg-RX-API-DMAC7.html)
ES (1) ES2189820T3 (cg-RX-API-DMAC7.html)
FI (1) FI111264B (cg-RX-API-DMAC7.html)
FR (1) FR2718450B1 (cg-RX-API-DMAC7.html)
GB (1) GB2288174A (cg-RX-API-DMAC7.html)
GE (1) GEP19991836B (cg-RX-API-DMAC7.html)
HR (1) HRP950217B1 (cg-RX-API-DMAC7.html)
HU (1) HU215396B (cg-RX-API-DMAC7.html)
IL (1) IL112954A (cg-RX-API-DMAC7.html)
IS (1) IS1865B (cg-RX-API-DMAC7.html)
JO (1) JO1850B1 (cg-RX-API-DMAC7.html)
LV (1) LV11182B (cg-RX-API-DMAC7.html)
MA (1) MA23501A1 (cg-RX-API-DMAC7.html)
MD (1) MD663G2 (cg-RX-API-DMAC7.html)
MY (1) MY114672A (cg-RX-API-DMAC7.html)
NO (1) NO308361B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ284498A (cg-RX-API-DMAC7.html)
OA (1) OA10200A (cg-RX-API-DMAC7.html)
PE (1) PE2896A1 (cg-RX-API-DMAC7.html)
PL (1) PL180837B1 (cg-RX-API-DMAC7.html)
PT (1) PT676409E (cg-RX-API-DMAC7.html)
RO (1) RO115634B1 (cg-RX-API-DMAC7.html)
RU (1) RU2141965C1 (cg-RX-API-DMAC7.html)
SA (1) SA97170757A (cg-RX-API-DMAC7.html)
SI (1) SI0676409T1 (cg-RX-API-DMAC7.html)
SK (1) SK284079B6 (cg-RX-API-DMAC7.html)
SV (1) SV1995000018A (cg-RX-API-DMAC7.html)
TN (1) TNSN95026A1 (cg-RX-API-DMAC7.html)
TW (1) TW316908B (cg-RX-API-DMAC7.html)
UA (1) UA44705C2 (cg-RX-API-DMAC7.html)
WO (1) WO1995027720A1 (cg-RX-API-DMAC7.html)
YU (1) YU49221B (cg-RX-API-DMAC7.html)
ZA (1) ZA952059B (cg-RX-API-DMAC7.html)

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FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
DE69723848T2 (de) * 1996-05-07 2004-07-01 Abbott Laboratories, Abbott Park 3-descladinose-2,3-anhydroerythromycin-derivate
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
IL128681A0 (en) * 1996-09-04 2000-01-31 Abbott Lab 6-O substituted ketolides having antibacterial activity
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
WO1998040392A1 (fr) * 1997-03-10 1998-09-17 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
AU6421398A (en) * 1997-03-24 1998-10-20 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
AU6932098A (en) * 1997-05-09 1998-12-08 Pfizer Products Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
EP0988308A1 (en) * 1997-06-11 2000-03-29 Pfizer Products Inc. 9-oxime erythromycin derivatives
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
EP1115732B1 (en) 1998-09-22 2005-06-29 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
ATE344269T1 (de) 1998-12-10 2006-11-15 Pfizer Prod Inc Carbamat und carbazat ketolid antibiotika
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
FR2789392B1 (fr) 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
AU773678B2 (en) * 1999-04-16 2004-06-03 Kosan Biosciences, Inc. Macrolide antiinfective agents
AU4354900A (en) 1999-04-16 2000-11-02 Kosan Biosciences, Inc. Ketolide antibacterials
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
OA11945A (en) * 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
EP1404693A2 (en) * 2001-07-03 2004-04-07 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
CN105039464A (zh) 2002-07-01 2015-11-11 阿基昂生命科学公司,以生物技术资源部的名义经营 用于生产葡糖胺和n-乙酰氨基葡糖的方法和物质
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WO2004096822A2 (en) * 2003-04-25 2004-11-11 Chiron Corporation Pyridyl substituted ketolide antibiotics
WO2004096823A2 (en) * 2003-04-25 2004-11-11 Chiron Corporation Novel ketolide derivatives
JP5698979B2 (ja) 2007-10-25 2015-04-08 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド系抗菌剤の調製プロセス
HRP20160222T1 (hr) * 2008-10-24 2016-04-08 Cempra Pharmaceuticals, Inc. Biozaštite uporabom makrolida koji sadrže triazol
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
WO2011032052A1 (en) 2009-09-10 2011-03-17 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
KR102006200B1 (ko) 2010-03-22 2019-08-01 셈프라 파마슈티컬스, 인크. 매크로라이드의 결정 형태들 및 그 용도들
EP2571506B1 (en) 2010-05-20 2017-05-10 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
KR20130120458A (ko) 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
EP2968801B1 (en) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
AU2014248014B2 (en) 2013-04-04 2018-11-08 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
JP2017531663A (ja) 2014-10-08 2017-10-26 プレジデント アンド フェローズ オブ ハーバード カレッジ １４員ケトライドならびにそれらの調製および使用の方法
EP3273969A4 (en) 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

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US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
AT342770B (de) * 1975-04-07 1978-04-25 Thomae Gmbh Dr K Verfahren zur herstellung neuer erythromycinderivate
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
AU684939B2 (en) 1998-01-08
IL112954A0 (en) 1995-06-29
SV1995000018A (es) 1997-10-24
TW316908B (cg-RX-API-DMAC7.html) 1997-10-01
MD663F1 (ro) 1997-01-31
MD663G2 (ro) 1997-07-31
BG61916B1 (bg) 1998-09-30
NO954942L (no) 1996-02-07
RO115634B1 (ro) 2000-04-28
DZ1869A1 (fr) 2002-02-17
KR100317148B1 (ko) 2002-06-22
EE9500080A (et) 1996-12-16
HRP950217A2 (en) 1997-08-31
SK154695A3 (en) 1996-10-02
US5656607A (en) 1997-08-12
AU2310795A (en) 1995-10-30
CN1126997A (zh) 1996-07-17
EE04498B1 (et) 2005-06-15
AP9500743A0 (en) 1995-07-31
DK0676409T3 (da) 2003-06-23
YU21695A (sh) 1997-12-05
LV11182B (en) 1997-04-20
PE2896A1 (es) 1996-02-12
PL180837B1 (pl) 2001-04-30
DE69529934T2 (de) 2003-09-04
PT676409E (pt) 2003-08-29
FR2718450A1 (fr) 1995-10-13
IS4309A (is) 1995-11-17
CA2164638C (fr) 2003-12-30
IL112954A (en) 2000-07-16
GB2288174A (en) 1995-10-11
CZ322395A3 (en) 1996-08-14
IS1865B (is) 2003-05-02
NO308361B1 (no) 2000-09-04
DE69529934D1 (de) 2003-04-24
HU215396B (hu) 1998-12-28
JP3000023B2 (ja) 2000-01-17
CO4370097A1 (es) 1996-10-07
ES2189820T3 (es) 2003-07-16
LV11182A (lv) 1996-04-20
GB9506856D0 (en) 1995-05-24
SI0676409T1 (en) 2003-06-30
HU9503505D0 (en) 1996-02-28
SK284079B6 (sk) 2004-09-08
NZ284498A (en) 1997-07-27
UA44705C2 (uk) 2002-03-15
ZA952059B (en) 1996-03-13
FI955913A7 (fi) 1995-12-08
RU2141965C1 (ru) 1999-11-27
CA2164638A1 (fr) 1995-10-19
AP587A (en) 1997-04-29
BR9506147A (pt) 1996-04-16
OA10200A (fr) 1996-12-18
GEP19991836B (en) 1999-11-05
HRP950217B1 (en) 2004-06-30
FR2718450B1 (fr) 1997-01-10
NO954942D0 (no) 1995-12-06
MY114672A (en) 2002-12-31
MA23501A1 (fr) 1995-12-31
PL311871A1 (en) 1996-03-18
US5760233A (en) 1998-06-02
ATE234853T1 (de) 2003-04-15
HUT73772A (en) 1996-09-30
BG100150A (bg) 1996-06-28
CZ296005B6 (cs) 2005-12-14
FI111264B (fi) 2003-06-30
CN1059445C (zh) 2000-12-13
TNSN95026A1 (fr) 1996-02-06
WO1995027720A1 (fr) 1995-10-19
FI955913A0 (fi) 1995-12-08
EP0676409A1 (fr) 1995-10-11
JPH07278177A (ja) 1995-10-24
EP0676409B1 (fr) 2003-03-19
JO1850B1 (en) 1995-12-27
SA97170757A (ar) 2005-12-03

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