UA108363C2 - Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування - Google Patents

Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування

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Publication number
UA108363C2
UA108363C2 UAA201205617A UAA201205617A UA108363C2 UA 108363 C2 UA108363 C2 UA 108363C2 UA A201205617 A UAA201205617 A UA A201205617A UA A201205617 A UAA201205617 A UA A201205617A UA 108363 C2 UA108363 C2 UA 108363C2
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UA
Ukraine
Prior art keywords
compounds
iminotiadiasiadioxide
oxides
compositions
applications
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Application number
UAA201205617A
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English (en)
Ukrainian (uk)
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Application filed filed Critical
Publication of UA108363C2 publication Critical patent/UA108363C2/ru

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C309/01—Sulfonic acids
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12—Nitrogen atoms not forming part of a nitro radical
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  • Chemical & Material Sciences (AREA)
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  • Diabetes (AREA)
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  • Psychology (AREA)
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  • Obesity (AREA)
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  • Communicable Diseases (AREA)
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  • Urology & Nephrology (AREA)
UAA201205617A 2009-10-08 2010-06-10 Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування UA108363C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24968509P 2009-10-08 2009-10-08
PCT/US2010/051553 WO2011044181A1 (en) 2009-10-08 2010-10-06 Iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use

Publications (1)

Publication Number Publication Date
UA108363C2 true UA108363C2 (uk) 2015-04-27

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UAA201205617A UA108363C2 (uk) 2009-10-08 2010-06-10 Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування

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US (6) US8729071B2 (ru)
EP (2) EP3034080B1 (ru)
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KR (3) KR101435301B1 (ru)
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AR (1) AR078534A1 (ru)
AU (1) AU2010303591B2 (ru)
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DO (1) DOP2012000067A (ru)
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PE (1) PE20141935A1 (ru)
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