TW201119673A - Dual variable domain immunoglobulins and uses thereof - Google Patents

Dual variable domain immunoglobulins and uses thereof Download PDF

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Publication number
TW201119673A
TW201119673A TW099129545A TW99129545A TW201119673A TW 201119673 A TW201119673 A TW 201119673A TW 099129545 A TW099129545 A TW 099129545A TW 99129545 A TW99129545 A TW 99129545A TW 201119673 A TW201119673 A TW 201119673A
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Taiwan
Prior art keywords
disease
antibody
antigen
binding protein
seq
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TW099129545A
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English (en)
Chinese (zh)
Inventor
Tariq Ghayur
jun-jian Liu
Sharmila Manoj
Susan E Brophy
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Abbott Lab
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Application filed by Abbott Lab filed Critical Abbott Lab
Publication of TW201119673A publication Critical patent/TW201119673A/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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