TW200738177A

TW200738177A - High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith

High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith Download PDF

Info

Publication number: TW200738177A
Authority: TW; Taiwan
Prior art keywords: composition; acid; functional; sweet taste; rebaudioside
Prior art date: 2005-11-23

Application number

TW95142858A

Other languages

English (en)

Chinese (zh)

Inventor

Grant E Dubois

Indra Prakash

Original Assignee

Coca Cola Co

Priority date

2005-11-23

Filing date

2006-11-20

Publication date

2007-10-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37907162&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200738177(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-11-20 Application filed by Coca Cola Co filed Critical Coca Cola Co

2007-10-16 Publication of TW200738177A publication Critical patent/TW200738177A/zh

Links

239000000203 mixture Substances 0.000 title claims description 269
235000003599 food sweetener Nutrition 0.000 title claims description 187
239000003765 sweetening agent Substances 0.000 title claims description 187
239000006041 probiotic Substances 0.000 title claims description 67
235000018291 probiotics Nutrition 0.000 title claims description 67
235000013406 prebiotics Nutrition 0.000 title claims description 8
229920005862 polyol Polymers 0.000 claims description 395
150000003077 polyols Chemical class 0.000 claims description 395
150000001720 carbohydrates Chemical class 0.000 claims description 343
235000014633 carbohydrates Nutrition 0.000 claims description 343
239000002253 acid Substances 0.000 claims description 194
235000019605 sweet taste sensations Nutrition 0.000 claims description 173
229940024606 amino acid Drugs 0.000 claims description 120
235000001014 amino acid Nutrition 0.000 claims description 120
150000001413 amino acids Chemical class 0.000 claims description 119
239000003531 protein hydrolysate Substances 0.000 claims description 104
HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 claims description 100
235000000346 sugar Nutrition 0.000 claims description 100
239000001512 FEMA 4601 Substances 0.000 claims description 94
HELXLJCILKEWJH-SEAGSNCFSA-N Rebaudioside A Natural products O=C(O[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)[C@@]1(C)[C@@H]2[C@](C)([C@H]3[C@@]4(CC(=C)[C@@](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@H](O)[C@@H](CO)O5)(C4)CC3)CC2)CCC1 HELXLJCILKEWJH-SEAGSNCFSA-N 0.000 claims description 94
HELXLJCILKEWJH-UHFFFAOYSA-N entered according to Sigma 01432 Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC(C1OC2C(C(O)C(O)C(CO)O2)O)OC(CO)C(O)C1OC1OC(CO)C(O)C(O)C1O HELXLJCILKEWJH-UHFFFAOYSA-N 0.000 claims description 94
235000019203 rebaudioside A Nutrition 0.000 claims description 94
235000002639 sodium chloride Nutrition 0.000 claims description 92
150000001875 compounds Chemical class 0.000 claims description 83
150000003839 salts Chemical class 0.000 claims description 82
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 76
150000007524 organic acids Chemical class 0.000 claims description 74
150000007522 mineralic acids Chemical class 0.000 claims description 64
235000018102 proteins Nutrition 0.000 claims description 64
102000004169 proteins and genes Human genes 0.000 claims description 64
108090000623 proteins and genes Proteins 0.000 claims description 63
229920000642 polymer Polymers 0.000 claims description 61
108010009736 Protein Hydrolysates Proteins 0.000 claims description 56
229930003935 flavonoid Natural products 0.000 claims description 56
150000002215 flavonoids Chemical class 0.000 claims description 56
235000017173 flavonoids Nutrition 0.000 claims description 56
241000186000 Bifidobacterium Species 0.000 claims description 54
239000004094 surface-active agent Substances 0.000 claims description 52
-1 durcoside B Chemical compound 0.000 claims description 50
241000894006 Bacteria Species 0.000 claims description 39
229920001542 oligosaccharide Polymers 0.000 claims description 39
235000019640 taste Nutrition 0.000 claims description 34
230000000529 probiotic effect Effects 0.000 claims description 27
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
235000010357 aspartame Nutrition 0.000 claims description 20
241000186012 Bifidobacterium breve Species 0.000 claims description 19
241000186660 Lactobacillus Species 0.000 claims description 19
235000013305 food Nutrition 0.000 claims description 18
239000000463 material Substances 0.000 claims description 18
229960005190 phenylalanine Drugs 0.000 claims description 18
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 17
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 17
235000009508 confectionery Nutrition 0.000 claims description 17
239000008103 glucose Substances 0.000 claims description 17
229930006000 Sucrose Natural products 0.000 claims description 16
235000013361 beverage Nutrition 0.000 claims description 16
229940039696 lactobacillus Drugs 0.000 claims description 16
QSRAJVGDWKFOGU-WBXIDTKBSA-N rebaudioside c Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]1(CC[C@H]2[C@@]3(C)[C@@H]([C@](CCC3)(C)C(=O)O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)CC3)C(=C)C[C@]23C1 QSRAJVGDWKFOGU-WBXIDTKBSA-N 0.000 claims description 16
239000005720 sucrose Substances 0.000 claims description 16
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 15
235000019202 steviosides Nutrition 0.000 claims description 15
235000015097 nutrients Nutrition 0.000 claims description 14
150000002482 oligosaccharides Chemical class 0.000 claims description 14
FGOJCPKOOGIRPA-UHFFFAOYSA-N 1-o-tert-butyl 4-o-ethyl 5-oxoazepane-1,4-dicarboxylate Chemical compound CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CCC1=O FGOJCPKOOGIRPA-UHFFFAOYSA-N 0.000 claims description 12
GIPHUOWOTCAJSR-UHFFFAOYSA-N Rebaudioside A. Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC1OC(CO)C(O)C(O)C1OC(C1O)OC(CO)C(O)C1OC1OC(CO)C(O)C(O)C1O GIPHUOWOTCAJSR-UHFFFAOYSA-N 0.000 claims description 12
241000193830 Bacillus <bacterium> Species 0.000 claims description 11
239000003995 emulsifying agent Substances 0.000 claims description 10
RPYRMTHVSUWHSV-CUZJHZIBSA-N rebaudioside D Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RPYRMTHVSUWHSV-CUZJHZIBSA-N 0.000 claims description 10
UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 9
239000000605 aspartame Substances 0.000 claims description 9
229960003438 aspartame Drugs 0.000 claims description 9
YILGKTWKKDLHAF-DUXFSIBLSA-M chembl2368344 Chemical compound [Na+].O([C@@H]1[C@H](CO)O[C@H]([C@H]([C@H]1O)O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C([O-])=O)[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O YILGKTWKKDLHAF-DUXFSIBLSA-M 0.000 claims description 9
229910017053 inorganic salt Inorganic materials 0.000 claims description 9
239000002304 perfume Substances 0.000 claims description 9
229920001308 poly(aminoacid) Polymers 0.000 claims description 9
235000019204 saccharin Nutrition 0.000 claims description 9
CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims description 9
229940081974 saccharin Drugs 0.000 claims description 9
239000000901 saccharin and its Na,K and Ca salt Substances 0.000 claims description 9
OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 9
229940013618 stevioside Drugs 0.000 claims description 9
WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 claims description 8
108010011485 Aspartame Proteins 0.000 claims description 8
239000001776 FEMA 4720 Substances 0.000 claims description 8
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 8
IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 8
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 8
QRGRAFPOLJOGRV-UHFFFAOYSA-N rebaudioside F Natural products CC12CCCC(C)(C1CCC34CC(=C)C(CCC23)(C4)OC5OC(CO)C(O)C(OC6OCC(O)C(O)C6O)C5OC7OC(CO)C(O)C(O)C7O)C(=O)OC8OC(CO)C(O)C(O)C8O QRGRAFPOLJOGRV-UHFFFAOYSA-N 0.000 claims description 8
HYLAUKAHEAUVFE-AVBZULRRSA-N rebaudioside f Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)CO1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HYLAUKAHEAUVFE-AVBZULRRSA-N 0.000 claims description 8
229940088594 vitamin Drugs 0.000 claims description 8
229930003231 vitamin Natural products 0.000 claims description 8
235000013343 vitamin Nutrition 0.000 claims description 8
239000011782 vitamin Substances 0.000 claims description 8
TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 7
150000007513 acids Chemical class 0.000 claims description 7
150000001412 amines Chemical class 0.000 claims description 7
229930182470 glycoside Natural products 0.000 claims description 7
150000002338 glycosides Chemical class 0.000 claims description 7
HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 7
235000005985 organic acids Nutrition 0.000 claims description 7
229960003104 ornithine Drugs 0.000 claims description 7
235000010447 xylitol Nutrition 0.000 claims description 7
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HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 7
229960002675 xylitol Drugs 0.000 claims description 7
239000001329 FEMA 3811 Substances 0.000 claims description 6
240000001046 Lactobacillus acidophilus Species 0.000 claims description 6
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240000001929 Lactobacillus brevis Species 0.000 claims description 6
235000013957 Lactobacillus brevis Nutrition 0.000 claims description 6
239000004472 Lysine Substances 0.000 claims description 6
TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 6
239000004384 Neotame Substances 0.000 claims description 6
RLLCWNUIHGPAJY-RYBZXKSASA-N Rebaudioside E Natural products O=C(O[C@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)[C@@H](O)[C@@H](O)[C@H](CO)O1)[C@]1(C)[C@@H]2[C@@](C)([C@@H]3[C@@]4(CC(=C)[C@@](O[C@@H]5[C@@H](O[C@@H]6[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O6)[C@H](O)[C@@H](O)[C@H](CO)O5)(C4)CC3)CC2)CCC1 RLLCWNUIHGPAJY-RYBZXKSASA-N 0.000 claims description 6
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
244000228451 Stevia rebaudiana Species 0.000 claims description 6
239000004376 Sucralose Substances 0.000 claims description 6
235000019534 high fructose corn syrup Nutrition 0.000 claims description 6
229940039695 lactobacillus acidophilus Drugs 0.000 claims description 6
235000013336 milk Nutrition 0.000 claims description 6
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ITVGXXMINPYUHD-CUVHLRMHSA-N neohesperidin dihydrochalcone Chemical compound C1=C(O)C(OC)=CC=C1CCC(=O)C(C(=C1)O)=C(O)C=C1O[C@H]1[C@H](O[C@H]2[C@@H]([C@H](O)[C@@H](O)[C@H](C)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 ITVGXXMINPYUHD-CUVHLRMHSA-N 0.000 claims description 6
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RLLCWNUIHGPAJY-SFUUMPFESA-N rebaudioside E Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RLLCWNUIHGPAJY-SFUUMPFESA-N 0.000 claims description 6
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PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 claims description 4
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XNLFIERPGXTDDP-UHFFFAOYSA-N periandrin i Chemical compound C1CC(C2C(C3(CCC4(C)CCC(C)(C=C4C3CC2)C(O)=O)C)(C)CC2)(C=O)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O XNLFIERPGXTDDP-UHFFFAOYSA-N 0.000 claims description 4
229920000724 poly(L-arginine) polymer Polymers 0.000 claims description 4
XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims description 4
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