SU1436882A3 - Способ получени дифенилметилового эфира 7-бензилиденамино-3-(3-хлор-1-пропен-1-ил)-3-цефем-4-карбоновой кислоты - Google Patents

Способ получени дифенилметилового эфира 7-бензилиденамино-3-(3-хлор-1-пропен-1-ил)-3-цефем-4-карбоновой кислоты Download PDF

Info

Publication number
SU1436882A3
SU1436882A3 SU864020682A SU4020682A SU1436882A3 SU 1436882 A3 SU1436882 A3 SU 1436882A3 SU 864020682 A SU864020682 A SU 864020682A SU 4020682 A SU4020682 A SU 4020682A SU 1436882 A3 SU1436882 A3 SU 1436882A3
Authority
SU
USSR - Soviet Union
Prior art keywords
cephem
carboxylic acid
formula
amino
propen
Prior art date
Application number
SU864020682A
Other languages
English (en)
Russian (ru)
Inventor
Ока Масахиса
Ямасита Харухиро
Наито Такаюки
Окумура Юн
Original Assignee
Бристоль-Мейерз Компани (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бристоль-Мейерз Компани (Фирма) filed Critical Бристоль-Мейерз Компани (Фирма)
Application granted granted Critical
Publication of SU1436882A3 publication Critical patent/SU1436882A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SU864020682A 1984-04-09 1986-02-06 Способ получени дифенилметилового эфира 7-бензилиденамино-3-(3-хлор-1-пропен-1-ил)-3-цефем-4-карбоновой кислоты SU1436882A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59794184A 1984-04-09 1984-04-09

Publications (1)

Publication Number Publication Date
SU1436882A3 true SU1436882A3 (ru) 1988-11-07

Family

ID=24393575

Family Applications (4)

Application Number Title Priority Date Filing Date
SU864020682A SU1436882A3 (ru) 1984-04-09 1986-02-06 Способ получени дифенилметилового эфира 7-бензилиденамино-3-(3-хлор-1-пропен-1-ил)-3-цефем-4-карбоновой кислоты
SU864023036A SU1367858A3 (ru) 1984-04-09 1986-02-06 Способ получени производных цефалоспорина
SU864019975A SU1487814A3 (ru) 1984-04-09 1986-02-06 СПОСОБ ПОЛУЧЕНИЯ 7-АМИНО-З-[3(4-КАРБАМОИЛ-1-ПИРИДИНИО)-1-ПРОПЕН1-ИЛ]-3-ЦЕФЕМ-4-КАРБОКСИЛАТА ч.
SU864018257A SU1375140A3 (ru) 1984-04-09 1986-02-06 Способ получени производных цефалоспорина или их аддитивных солей с галоидводородными кислотами

Family Applications After (3)

Application Number Title Priority Date Filing Date
SU864023036A SU1367858A3 (ru) 1984-04-09 1986-02-06 Способ получени производных цефалоспорина
SU864019975A SU1487814A3 (ru) 1984-04-09 1986-02-06 СПОСОБ ПОЛУЧЕНИЯ 7-АМИНО-З-[3(4-КАРБАМОИЛ-1-ПИРИДИНИО)-1-ПРОПЕН1-ИЛ]-3-ЦЕФЕМ-4-КАРБОКСИЛАТА ч.
SU864018257A SU1375140A3 (ru) 1984-04-09 1986-02-06 Способ получени производных цефалоспорина или их аддитивных солей с галоидводородными кислотами

Country Status (31)

Country Link
JP (4) JPS615084A (es)
KR (1) KR870002166B1 (es)
AR (1) AR244694A1 (es)
AT (1) AT388735B (es)
AU (2) AU580990B2 (es)
BE (1) BE902148A (es)
CA (3) CA1276929C (es)
CH (1) CH669197A5 (es)
DD (3) DD249024A5 (es)
DE (1) DE3512225A1 (es)
DK (1) DK155985A (es)
ES (4) ES8607318A1 (es)
FI (1) FI84830C (es)
FR (1) FR2563832B1 (es)
GB (3) GB2157293B (es)
GR (1) GR850883B (es)
HU (2) HU204277B (es)
IE (2) IE58408B1 (es)
IL (1) IL74826A (es)
IT (1) IT1190353B (es)
LU (1) LU85840A1 (es)
MY (1) MY101940A (es)
NL (1) NL192925C (es)
NZ (1) NZ211659A (es)
OA (1) OA07985A (es)
PT (1) PT80246B (es)
RU (1) RU2056425C1 (es)
SE (4) SE466205B (es)
SU (4) SU1436882A3 (es)
YU (2) YU46151B (es)
ZA (1) ZA852236B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145186A (ja) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd 新規セフエム化合物及びその製造法
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
ATE114657T1 (de) * 1985-12-26 1994-12-15 Eisai Co Ltd Cephalosporin-verbindungen.
AU614723B2 (en) * 1986-10-13 1991-09-12 Eisai Co. Ltd. 3-propenylcephem derivative
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
JPH085897B2 (ja) * 1986-11-06 1996-01-24 エーザイ株式会社 ３−プロペニルセフェム誘導体
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
CA1339738C (en) * 1988-03-16 1998-03-17 Takashi Kamiya Process for the preparation of cephem derivatives and entermediates therefor
JPH0699449B2 (ja) * 1988-03-16 1994-12-07 エーザイ株式会社 セフェム誘導体の合成中間体
FR2655042B1 (fr) * 1989-11-29 1994-01-21 Adir Cie Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
JPH0741484A (ja) * 1993-07-29 1995-02-10 Katayama Seiyakushiyo:Kk セフェム化合物及び抗菌剤
KR100248851B1 (ko) * 1994-08-16 2000-04-01 이치로 키타사토 신규 세펨 유도체
WO1999067255A1 (en) 1998-06-22 1999-12-29 F. Hoffmann-La Roche Ag Propenyl cephalosporin derivatives
WO2005026176A1 (ja) 2003-09-09 2005-03-24 Nippon Chemical Industrial Co.,Ltd. ３−クロロメチル-３-セフェム誘導体の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
EP0025017A1 (de) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (es) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
GR78245B (es) * 1980-09-12 1984-09-26 Ciba Geigy Ag
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент СССР № 1181548А, кл. С 07 D 501/18, 1979. Патент US № 4065620, кл. 544-16, опублик.1977. Патент US № 4110534, кл. 544-16, опублик, 1978. *

Also Published As

Publication number Publication date
ES8706694A1 (es) 1987-07-01
GR850883B (es) 1985-11-25
NZ211659A (en) 1988-11-29
RU2056425C1 (ru) 1996-03-20
IL74826A (en) 1990-01-18
SE8501680D0 (sv) 1985-04-03
JPS61143387A (ja) 1986-07-01
GB2157293B (en) 1988-10-05
AU610278B2 (en) 1991-05-16
JPS61143391A (ja) 1986-07-01
IE58408B1 (en) 1993-09-22
JPS615084A (ja) 1986-01-10
JPH0351716B2 (es) 1991-08-07
ES8706155A1 (es) 1987-06-01
FI84830C (fi) 1992-01-27
AT388735B (de) 1989-08-25
NL192925C (nl) 1998-05-07
JPH0262557B2 (es) 1990-12-26
JPH0357106B2 (es) 1991-08-30
AR244694A1 (es) 1993-11-30
KR850007424A (ko) 1985-12-04
SE8901226D0 (sv) 1989-04-06
SE466205B (sv) 1992-01-13
AU4086285A (en) 1985-10-17
YU60085A (en) 1987-12-31
NL192925B (nl) 1998-01-05
ES551550A0 (es) 1987-06-01
ES551551A0 (es) 1987-07-01
CH669197A5 (de) 1989-02-28
CA1340638C (en) 1999-07-06
ES8607318A1 (es) 1986-06-16
GB2194789A (en) 1988-03-16
SE8901224L (sv) 1989-04-06
IL74826A0 (en) 1985-07-31
IT8520267A0 (it) 1985-04-05
OA07985A (fr) 1987-01-31
GB2194790A (en) 1988-03-16
SE8901225L (sv) 1989-04-06
FI84830B (fi) 1991-10-15
GB2157293A (en) 1985-10-23
SE8901224D0 (sv) 1989-04-06
HUT37622A (en) 1986-01-23
ATA103985A (de) 1989-01-15
HU204277B (en) 1991-12-30
IE58403B1 (en) 1993-09-22
GB2194790B (en) 1988-10-05
ES8800949A1 (es) 1987-12-01
DD249024A5 (de) 1987-08-26
DD236735A5 (de) 1986-06-18
SE8901226L (sv) 1989-04-06
YU118987A (en) 1988-10-31
FR2563832A1 (fr) 1985-11-08
MY101940A (en) 1992-02-15
GB8508846D0 (en) 1985-05-09
DK155985D0 (da) 1985-04-03
JPS61143390A (ja) 1986-07-01
BE902148A (fr) 1985-10-09
SE470259B (sv) 1993-12-20
HU193750B (en) 1987-11-30
FI851379L (fi) 1985-10-10
AU580990B2 (en) 1989-02-09
NL8501002A (nl) 1985-11-01
ES557060A0 (es) 1987-12-01
GB8721347D0 (en) 1987-10-14
SU1375140A3 (ru) 1988-02-15
GB8721346D0 (en) 1987-10-14
DE3512225C2 (es) 1990-02-22
LU85840A1 (fr) 1985-12-16
KR870002166B1 (ko) 1987-12-14
YU46213B (sh) 1993-05-28
GB2194789B (en) 1988-10-12
CA1276929C (en) 1990-11-27
ZA852236B (en) 1985-11-27
DK155985A (da) 1985-10-10
SE470260B (sv) 1993-12-20
SU1367858A3 (ru) 1988-01-15
FI851379A0 (fi) 1985-04-04
PT80246B (pt) 1987-10-20
FR2563832B1 (fr) 1989-08-18
YU46151B (sh) 1993-05-28
IE850866L (en) 1985-10-09
SE8501680L (sv) 1985-10-10
AU2504188A (en) 1989-03-02
IT1190353B (it) 1988-02-16
DD251752A5 (de) 1987-11-25
SE505256C2 (sv) 1997-07-21
JPH0350754B2 (es) 1991-08-02
ES542013A0 (es) 1986-06-16
SU1487814A3 (ru) 1989-06-15
PT80246A (en) 1985-05-01
DE3512225A1 (de) 1985-10-17
CA1340672C (en) 1999-07-20
SE8901225D0 (sv) 1989-04-06

Similar Documents

Publication Publication Date Title
SU1436882A3 (ru) Способ получени дифенилметилового эфира 7-бензилиденамино-3-(3-хлор-1-пропен-1-ил)-3-цефем-4-карбоновой кислоты
SE434949B (sv) Forfarande for framstellning av 7beta-acylamino-7alfa-alkoxicefalosporiner eller 6beta-acylamino-6alfa-alkoxipenicilliner
DK163584B (da) 7-amino-3-propenylcephalosporinsyrederivater samt fremgangsmaade til fremstilling deraf
US4139618A (en) Cephalosporin type antibacterials
US4699979A (en) 7-amino-3-propenylcephalosporanic acid and esters thereof
US4094978A (en) 3-propenyl derivatives of cephalosporin, compositions and their use
US5919939A (en) Preparation of cephem and isooxacephem derivatives
FI75165B (fi) Foerbaettrat foerfarande foer framstaellning av penicillansyraklormetylestrar.
US3998817A (en) Process for producing cephalosporanic acid derivatives
KR870002181B1 (ko) 세팔로스포린의 제조방법
EP0055933B1 (en) 6-(2-aryl-2-(1,1-dioxopenicillanoyloxy-methoxycarbonyl)acetamido) penicillanic acids
US4051131A (en) Intermediates for preparing cephalosporins
EP0117872B1 (en) Process for preparing cephalosporin compounds
SU797579A3 (ru) Способ получени амидов кислот или ихСОлЕй C щЕлОчНыМи МЕТАллАМи или ТРиАл-КилАМиНАМи
SU685157A3 (ru) Способ получени 7-амино-3-/ (1-карбоксиметилтетразол-5-ил)тисметил/-3-пефем-4-карбоновой кислоты
US4171303A (en) Process for the preparation of reactive penicillanic acid and cephalosporanic acid derivatives
US3965098A (en) Intermediates for preparing cephalosporins and methods of production
US4210750A (en) Process for the preparation of 3-carbamoyl cephalosporins using isocyanates
US4959495A (en) Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins
US3799922A (en) 4-substituted 3-cephem compounds
US3971780A (en) Thio-β-lactam cephalosporins
EP0049309B1 (en) Cephem derivatives, process for producing thereof, and antibacterial agents comprising said compounds
US4659812A (en) Cephalosporin intermediates
EP0096496B1 (en) Preparation of penicillin and cephalosporin compounds and novel intermediates useful therein
US4150224A (en) 7[[(1-Pyrrollyl)7 acetyl]amino]cephalosporin derivatives