SK285757B6 - Ftalazíny s aktivitou inhibujúcou angiogenézu, spôsob ich prípravy, ich použitie a prostriedky, ktoré ich obsahujú - Google Patents

Ftalazíny s aktivitou inhibujúcou angiogenézu, spôsob ich prípravy, ich použitie a prostriedky, ktoré ich obsahujú Download PDF

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Publication number
SK285757B6
SK285757B6 SK1096-99A SK109699A SK285757B6 SK 285757 B6 SK285757 B6 SK 285757B6 SK 109699 A SK109699 A SK 109699A SK 285757 B6 SK285757 B6 SK 285757B6
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SK
Slovakia
Prior art keywords
group
phenyl
formula
alkyl
compound
Prior art date
Application number
SK1096-99A
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English (en)
Slovak (sk)
Other versions
SK109699A3 (en
Inventor
Guido Bold
J�rg FREI
Peter Traxler
Karl-Heinz Altmann
Helmut Mett
David Raymond Stover
Jeanette Wood
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK109699A3 publication Critical patent/SK109699A3/sk
Publication of SK285757B6 publication Critical patent/SK285757B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SK1096-99A 1997-02-13 1998-02-11 Ftalazíny s aktivitou inhibujúcou angiogenézu, spôsob ich prípravy, ich použitie a prostriedky, ktoré ich obsahujú SK285757B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH31597 1997-02-13
PCT/EP1998/000764 WO1998035958A1 (en) 1997-02-13 1998-02-11 Phthalazines with angiogenesis inhibiting activity

Publications (2)

Publication Number Publication Date
SK109699A3 SK109699A3 (en) 2000-03-13
SK285757B6 true SK285757B6 (sk) 2007-07-06

Family

ID=4184213

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1096-99A SK285757B6 (sk) 1997-02-13 1998-02-11 Ftalazíny s aktivitou inhibujúcou angiogenézu, spôsob ich prípravy, ich použitie a prostriedky, ktoré ich obsahujú

Country Status (32)

Country Link
US (3) US6258812B1 (de)
EP (1) EP0970070B1 (de)
JP (1) JP3544675B2 (de)
KR (1) KR100441362B1 (de)
CN (1) CN1251097B (de)
AR (1) AR011135A1 (de)
AT (1) ATE278686T1 (de)
AU (1) AU731852B2 (de)
BR (1) BR9807685B1 (de)
CA (1) CA2281721C (de)
CO (1) CO4950519A1 (de)
CY (1) CY2550B1 (de)
CZ (1) CZ297534B6 (de)
DE (1) DE69826841T2 (de)
DK (1) DK0970070T3 (de)
ES (1) ES2234097T3 (de)
HU (1) HU227972B1 (de)
ID (1) ID23698A (de)
IL (1) IL131273A0 (de)
MY (1) MY128645A (de)
NO (1) NO317367B1 (de)
NZ (1) NZ337064A (de)
PE (1) PE52499A1 (de)
PL (1) PL197371B1 (de)
PT (1) PT970070E (de)
RU (1) RU2207132C2 (de)
SI (1) SI0970070T1 (de)
SK (1) SK285757B6 (de)
TR (1) TR199901953T2 (de)
TW (1) TWI250151B (de)
WO (1) WO1998035958A1 (de)
ZA (1) ZA981155B (de)

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