SK285666B6 - Mikrogranuly omeprazolu s vonkajšou vrstvou, ktorá chráni pred žalúdočným prostredím, spôsob prípravy mikrogranúl - Google Patents

Mikrogranuly omeprazolu s vonkajšou vrstvou, ktorá chráni pred žalúdočným prostredím, spôsob prípravy mikrogranúl Download PDF

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Publication number
SK285666B6
SK285666B6 SK1141-2000A SK11412000A SK285666B6 SK 285666 B6 SK285666 B6 SK 285666B6 SK 11412000 A SK11412000 A SK 11412000A SK 285666 B6 SK285666 B6 SK 285666B6
Authority
SK
Slovakia
Prior art keywords
microgranules
hydrophobic
microgranules according
omeprazole
agent
Prior art date
Application number
SK1141-2000A
Other languages
English (en)
Slovak (sk)
Other versions
SK11412000A3 (sk
Inventor
Patrice Debregeas
G�Rard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9522415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK285666(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethypharm filed Critical Ethypharm
Publication of SK11412000A3 publication Critical patent/SK11412000A3/sk
Publication of SK285666B6 publication Critical patent/SK285666B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1141-2000A 1998-01-30 1998-08-10 Mikrogranuly omeprazolu s vonkajšou vrstvou, ktorá chráni pred žalúdočným prostredím, spôsob prípravy mikrogranúl SK285666B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9801098A FR2774288B1 (fr) 1998-01-30 1998-01-30 Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques
PCT/FR1998/001783 WO1999038511A1 (fr) 1998-01-30 1998-08-10 Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques

Publications (2)

Publication Number Publication Date
SK11412000A3 SK11412000A3 (sk) 2001-04-09
SK285666B6 true SK285666B6 (sk) 2007-05-03

Family

ID=9522415

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1141-2000A SK285666B6 (sk) 1998-01-30 1998-08-10 Mikrogranuly omeprazolu s vonkajšou vrstvou, ktorá chráni pred žalúdočným prostredím, spôsob prípravy mikrogranúl

Country Status (32)

Country Link
US (1) US6551621B1 (is)
EP (1) EP1051174B2 (is)
JP (1) JP4286452B2 (is)
KR (1) KR100510366B1 (is)
CN (1) CN1114405C (is)
AT (1) ATE232100T1 (is)
AU (1) AU755882B2 (is)
BG (1) BG65087B1 (is)
BR (1) BR9814924B1 (is)
CA (1) CA2319015C (is)
CZ (1) CZ299192B6 (is)
DE (1) DE69811278T3 (is)
DK (1) DK1051174T4 (is)
EA (1) EA002879B1 (is)
EE (1) EE05620B1 (is)
ES (1) ES2189232T5 (is)
FR (1) FR2774288B1 (is)
GE (1) GEP20032941B (is)
HK (1) HK1032354A1 (is)
HU (1) HU229956B1 (is)
IL (1) IL137536A0 (is)
IS (1) IS2866B (is)
NO (1) NO330144B1 (is)
NZ (1) NZ505998A (is)
PL (1) PL200043B1 (is)
PT (1) PT1051174E (is)
RS (1) RS50245B (is)
SI (1) SI1051174T2 (is)
SK (1) SK285666B6 (is)
TR (1) TR200002214T2 (is)
UA (1) UA61988C2 (is)
WO (1) WO1999038511A1 (is)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
FR2793688B1 (fr) * 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
EP1603537A4 (en) * 2003-02-20 2009-11-04 Santarus Inc IMMEDIATE RELEASE OF OMEPRAZOLE ANTACIDAL COMPLEX WITH NEW FORMULATION FOR RAPID AND PROLONGED ELIMINATION OF GASTRIC ACID
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
ES2234393B2 (es) * 2003-04-29 2006-09-01 Laboratorios Belmac, S.A. "formulaciones de pelets de compuestos bencimidazolicos antiulcerosos y labiles al acido".
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
TWI337877B (en) * 2003-07-18 2011-03-01 Santarus Inc Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
EP1648416A4 (en) * 2003-07-18 2012-03-28 Santarus Inc PHARMACEUTICAL FORMULATIONS FOR INHIBITING THE ACIDIC ACIDIFICATION AND MANUFACTURING AND USE METHOD
CN1874764B (zh) * 2003-10-10 2012-08-01 埃法尔姆公司 含有银杏提取物的持续释放微粒及其制备方法
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
JP2007522217A (ja) * 2004-02-10 2007-08-09 サンタラス インコーポレイティッド プロトンポンプ阻害剤、緩衝剤および非ステロイド系抗炎症薬の組み合わせ
WO2005117870A2 (en) * 2004-04-16 2005-12-15 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8461187B2 (en) 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
EP1965774A2 (en) * 2005-12-30 2008-09-10 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
PL2007362T3 (pl) 2006-04-04 2019-02-28 Kg Acquisition Llc Doustne postacie leku obejmujące czynnik przeciwpłytkowy i inhibitor kwasu
EP2026768B1 (en) * 2006-06-01 2018-02-28 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
EP2081546A2 (en) * 2006-10-17 2009-07-29 Ranbaxy Laboratories Limited Multiple unit tablet compositions of benzimidazole compounds
EA028049B1 (ru) 2011-12-28 2017-10-31 Поузен Инк. Улучшенные композиции и способы доставки омепразола и ацетилсалициловой кислоты
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
KR102633566B1 (ko) 2015-07-17 2024-02-05 비이 파벨 매뉴팩처링 액체 복용 형태로의 다층 약제학적 활성 화합물-방출 미세입자
EP3117824A1 (en) 2015-07-17 2017-01-18 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
US10736855B2 (en) 2016-02-25 2020-08-11 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
FR3078630B1 (fr) 2018-03-08 2021-05-14 Karim Ioualalen Mode de formulation sous forme de solide divise hydrophobe

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
JPH0768125B2 (ja) * 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
FR2692146B1 (fr) † 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
CA2201325A1 (en) * 1994-09-30 1996-04-11 Medical Security Corporation Method and system for cleaning and slip-resistant treatment of surface coverings
ES2094694B1 (es) † 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
CH687810A5 (de) 1995-05-24 1997-02-28 Mepha Ag Pelletformulierung mit Omeprazol.
PL186605B1 (pl) * 1995-09-21 2004-01-30 Pharma Pass Llc Tabletka lub mikrotabletka zawierająca rdzeń posiadający jako kwasolabilny składnik aktywny omeprazol oraz sposób wytwarzania tabletek lub mikrotabletek zawierających rdzeń posiadający jako kwasolabilny składnik aktywny omeprazol
WO1998019668A1 (en) * 1996-11-06 1998-05-14 Sharmatek, Inc. Delayed delivery system for acid-sensitive drugs
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
SE9704870D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I

Also Published As

Publication number Publication date
SI1051174T1 (en) 2003-06-30
BG65087B1 (bg) 2007-02-28
HU229956B1 (hu) 2015-03-02
JP2002501895A (ja) 2002-01-22
CA2319015C (fr) 2008-08-05
PT1051174E (pt) 2003-06-30
EA200000797A1 (ru) 2001-02-26
AU9074898A (en) 1999-08-16
PL342044A1 (en) 2001-05-21
US6551621B1 (en) 2003-04-22
EP1051174A1 (fr) 2000-11-15
BG104634A (bg) 2001-02-28
ES2189232T5 (es) 2012-11-07
NZ505998A (en) 2003-11-28
HUP0100347A3 (en) 2002-12-28
IS2866B (is) 2014-01-15
HUP0100347A2 (hu) 2001-10-28
EA002879B1 (ru) 2002-10-31
SK11412000A3 (sk) 2001-04-09
DK1051174T4 (da) 2012-10-01
AU755882B2 (en) 2003-01-02
PL200043B1 (pl) 2008-11-28
SI1051174T2 (sl) 2013-01-31
NO20004654D0 (no) 2000-09-18
UA61988C2 (uk) 2003-12-15
TR200002214T2 (tr) 2000-12-21
FR2774288A1 (fr) 1999-08-06
YU48400A (sh) 2003-02-28
CN1114405C (zh) 2003-07-16
EP1051174B2 (fr) 2012-07-04
GEP20032941B (en) 2003-04-25
CZ299192B6 (cs) 2008-05-14
FR2774288B1 (fr) 2001-09-07
BR9814924B1 (pt) 2010-07-13
CA2319015A1 (fr) 1999-08-05
CZ20002709A3 (cs) 2000-12-13
RS50245B (sr) 2009-07-15
EP1051174B1 (fr) 2003-02-05
WO1999038511A1 (fr) 1999-08-05
JP4286452B2 (ja) 2009-07-01
IL137536A0 (en) 2001-07-24
NO20004654L (no) 2000-09-18
BR9814924A (pt) 2000-10-17
CN1284877A (zh) 2001-02-21
DK1051174T3 (da) 2003-05-26
DE69811278T3 (de) 2012-11-29
DE69811278D1 (de) 2003-03-13
HK1032354A1 (en) 2001-07-20
IS5577A (is) 2000-07-25
EE05620B1 (et) 2013-02-15
EE200000466A (et) 2002-04-15
NO330144B1 (no) 2011-02-21
DE69811278T2 (de) 2003-11-27
ATE232100T1 (de) 2003-02-15
ES2189232T3 (es) 2003-07-01
KR20010040502A (ko) 2001-05-15
KR100510366B1 (ko) 2005-08-24

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Legal Events

Date Code Title Description
MK4A Expiry of patent

Expiry date: 20180810