PT1051174E - Microgranulos de omeprazole gastroprotegidos processo para os obter e preparacoes farmaceuticas - Google Patents

Microgranulos de omeprazole gastroprotegidos processo para os obter e preparacoes farmaceuticas

Info

Publication number
PT1051174E
PT1051174E PT98942718T PT98942718T PT1051174E PT 1051174 E PT1051174 E PT 1051174E PT 98942718 T PT98942718 T PT 98942718T PT 98942718 T PT98942718 T PT 98942718T PT 1051174 E PT1051174 E PT 1051174E
Authority
PT
Portugal
Prior art keywords
omeprazole
microgranules
gastroprotegidos
obtaining
preparing pharmaceutical
Prior art date
Application number
PT98942718T
Other languages
English (en)
Inventor
Patrice Debregeas
Gerard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9522415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1051174(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Publication of PT1051174E publication Critical patent/PT1051174E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PT98942718T 1998-01-30 1998-08-10 Microgranulos de omeprazole gastroprotegidos processo para os obter e preparacoes farmaceuticas PT1051174E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9801098A FR2774288B1 (fr) 1998-01-30 1998-01-30 Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques

Publications (1)

Publication Number Publication Date
PT1051174E true PT1051174E (pt) 2003-06-30

Family

ID=9522415

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98942718T PT1051174E (pt) 1998-01-30 1998-08-10 Microgranulos de omeprazole gastroprotegidos processo para os obter e preparacoes farmaceuticas

Country Status (32)

Country Link
US (1) US6551621B1 (pt)
EP (1) EP1051174B2 (pt)
JP (1) JP4286452B2 (pt)
KR (1) KR100510366B1 (pt)
CN (1) CN1114405C (pt)
AT (1) ATE232100T1 (pt)
AU (1) AU755882B2 (pt)
BG (1) BG65087B1 (pt)
BR (1) BR9814924B1 (pt)
CA (1) CA2319015C (pt)
CZ (1) CZ299192B6 (pt)
DE (1) DE69811278T3 (pt)
DK (1) DK1051174T4 (pt)
EA (1) EA002879B1 (pt)
EE (1) EE05620B1 (pt)
ES (1) ES2189232T5 (pt)
FR (1) FR2774288B1 (pt)
GE (1) GEP20032941B (pt)
HK (1) HK1032354A1 (pt)
HU (1) HU229956B1 (pt)
IL (1) IL137536A0 (pt)
IS (1) IS2866B (pt)
NO (1) NO330144B1 (pt)
NZ (1) NZ505998A (pt)
PL (1) PL200043B1 (pt)
PT (1) PT1051174E (pt)
RS (1) RS50245B (pt)
SI (1) SI1051174T2 (pt)
SK (1) SK285666B6 (pt)
TR (1) TR200002214T2 (pt)
UA (1) UA61988C2 (pt)
WO (1) WO1999038511A1 (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
FR2793688B1 (fr) * 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
JP2006518751A (ja) * 2003-02-20 2006-08-17 サンタラス インコーポレイティッド 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物
ES2234393B2 (es) * 2003-04-29 2006-09-01 Laboratorios Belmac, S.A. "formulaciones de pelets de compuestos bencimidazolicos antiulcerosos y labiles al acido".
CA2531564C (en) * 2003-07-18 2016-01-19 Santarus, Inc. Pharmaceutical composition for inhibiting acid secretion
TWI337877B (en) * 2003-07-18 2011-03-01 Santarus Inc Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP1689373B1 (en) * 2003-10-10 2019-04-03 Ethypharm Sustained-release microgranules containing ginkgo biloba extract and the process for manufacturing these
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
EP1718303A4 (en) * 2004-02-10 2010-09-01 Santarus Inc COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND NON-STEROIDAL ANTI-INFLAMMATORY DRUG
CA2561700A1 (en) * 2004-04-16 2005-12-15 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2570916C (en) 2004-06-16 2013-06-11 Tap Pharmaceutical Products, Inc. Pulsed release dosage form of a ppi
EP1965774A2 (en) * 2005-12-30 2008-09-10 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
KR101784001B1 (ko) 2006-04-04 2017-10-23 케이지 액퀴지션 엘엘씨 항혈소판제와 산 억제제를 포함하는 경구 투여용 약학 조성물
JP2009538901A (ja) * 2006-06-01 2009-11-12 デクセル ファーマ テクノロジーズ エルティーディー. 複式ユニット製薬的製剤
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
CA2667039A1 (en) * 2006-10-17 2008-04-24 Ranbaxy Laboratories Limited Multiple unit tablet compositions of benzimidazole compounds
US9539214B2 (en) 2011-12-28 2017-01-10 Pozen Inc. Compositions and methods for delivery of omeprazole plus acetylsalicylic acid
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
EP3117824A1 (en) 2015-07-17 2017-01-18 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
DK3324948T3 (da) 2015-07-17 2023-05-08 Be Pharbel Mfg Flerlagsmikropartikler til frigivelse af en farmaceutisk aktiv forbindelse i en flydende doseringsform
US10736855B2 (en) 2016-02-25 2020-08-11 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
FR3078630B1 (fr) 2018-03-08 2021-05-14 Karim Ioualalen Mode de formulation sous forme de solide divise hydrophobe

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
JPH0768125B2 (ja) * 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
AU4129496A (en) * 1994-09-30 1996-04-26 Medical Security Corporation Method and system for cleaning and slip-resistant treatment of surface coverings
ES2094694B1 (es) 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
CH687810A5 (de) 1995-05-24 1997-02-28 Mepha Ag Pelletformulierung mit Omeprazol.
ES2236628T3 (es) * 1995-09-21 2005-07-16 Pharma Pass Ii Llc Composicion farmaceutica que contiene un omeprazol labil de acido, y procedimiento para su preparacion.
ATE271379T1 (de) * 1996-11-06 2004-08-15 Wockhardt Europ Ltd System zur verzögerten freisetzung säurelabiler substanzen
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
SE9704870D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II

Also Published As

Publication number Publication date
SI1051174T1 (en) 2003-06-30
YU48400A (sh) 2003-02-28
EE200000466A (et) 2002-04-15
SK11412000A3 (sk) 2001-04-09
EA002879B1 (ru) 2002-10-31
DK1051174T3 (da) 2003-05-26
HU229956B1 (hu) 2015-03-02
CZ20002709A3 (cs) 2000-12-13
KR100510366B1 (ko) 2005-08-24
ES2189232T5 (es) 2012-11-07
NO20004654L (no) 2000-09-18
KR20010040502A (ko) 2001-05-15
NO20004654D0 (no) 2000-09-18
CZ299192B6 (cs) 2008-05-14
DE69811278D1 (de) 2003-03-13
CA2319015A1 (fr) 1999-08-05
AU755882B2 (en) 2003-01-02
EA200000797A1 (ru) 2001-02-26
IS2866B (is) 2014-01-15
NZ505998A (en) 2003-11-28
ES2189232T3 (es) 2003-07-01
RS50245B (sr) 2009-07-15
US6551621B1 (en) 2003-04-22
EP1051174B1 (fr) 2003-02-05
FR2774288B1 (fr) 2001-09-07
BG65087B1 (bg) 2007-02-28
IL137536A0 (en) 2001-07-24
EP1051174B2 (fr) 2012-07-04
FR2774288A1 (fr) 1999-08-06
AU9074898A (en) 1999-08-16
EP1051174A1 (fr) 2000-11-15
HUP0100347A2 (hu) 2001-10-28
DK1051174T4 (da) 2012-10-01
WO1999038511A1 (fr) 1999-08-05
JP2002501895A (ja) 2002-01-22
EE05620B1 (et) 2013-02-15
CN1114405C (zh) 2003-07-16
BG104634A (bg) 2001-02-28
JP4286452B2 (ja) 2009-07-01
HK1032354A1 (en) 2001-07-20
SK285666B6 (sk) 2007-05-03
BR9814924B1 (pt) 2010-07-13
CA2319015C (fr) 2008-08-05
PL342044A1 (en) 2001-05-21
BR9814924A (pt) 2000-10-17
CN1284877A (zh) 2001-02-21
TR200002214T2 (tr) 2000-12-21
GEP20032941B (en) 2003-04-25
PL200043B1 (pl) 2008-11-28
HUP0100347A3 (en) 2002-12-28
IS5577A (is) 2000-07-25
DE69811278T3 (de) 2012-11-29
ATE232100T1 (de) 2003-02-15
SI1051174T2 (sl) 2013-01-31
UA61988C2 (uk) 2003-12-15
NO330144B1 (no) 2011-02-21
DE69811278T2 (de) 2003-11-27

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