SK279249B6 - Ľudské monoklonálne protilátky a spôsob ich výroby - Google Patents

Ľudské monoklonálne protilátky a spôsob ich výroby Download PDF

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Publication number
SK279249B6
SK279249B6 SK3566-83A SK356683A SK279249B6 SK 279249 B6 SK279249 B6 SK 279249B6 SK 356683 A SK356683 A SK 356683A SK 279249 B6 SK279249 B6 SK 279249B6
Authority
SK
Slovakia
Prior art keywords
human
monoclonal antibodies
fusion
cells
hybridomas
Prior art date
Application number
SK3566-83A
Other languages
English (en)
Slovak (sk)
Other versions
SK356683A3 (en
Inventor
Hideaki Hagiwara
Harold H. Handley
Mark C. Glassy
Yoshihode Hagiwara
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of SK356683A3 publication Critical patent/SK356683A3/sk
Publication of SK279249B6 publication Critical patent/SK279249B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK3566-83A 1982-05-21 1983-05-19 Ľudské monoklonálne protilátky a spôsob ich výroby SK279249B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57084843A JPS58201994A (ja) 1982-05-21 1982-05-21 抗原特異的ヒト免疫グロブリンの生産方法

Publications (2)

Publication Number Publication Date
SK356683A3 SK356683A3 (en) 1998-08-05
SK279249B6 true SK279249B6 (sk) 1998-08-05

Family

ID=13842073

Family Applications (1)

Application Number Title Priority Date Filing Date
SK3566-83A SK279249B6 (sk) 1982-05-21 1983-05-19 Ľudské monoklonálne protilátky a spôsob ich výroby

Country Status (13)

Country Link
EP (1) EP0109441B1 (zh)
JP (2) JPS58201994A (zh)
AT (1) ATE114189T1 (zh)
AU (1) AU560595B2 (zh)
CZ (1) CZ280677B6 (zh)
DE (1) DE3382764T2 (zh)
DK (1) DK164510C (zh)
FI (1) FI86077C (zh)
HU (1) HU190908B (zh)
IN (1) IN157982B (zh)
SK (1) SK279249B6 (zh)
WO (1) WO1983004313A1 (zh)
ZA (1) ZA833686B (zh)

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US4886745A (en) * 1984-03-30 1989-12-12 Syntex Inc. Monoclonal antibody specific for human basal cell surface antigen
CA1320689C (en) * 1984-03-30 1993-07-27 Alain Schreiber Monoclonal antibody specific for human basal cell surface antigen
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US4761377A (en) * 1984-10-15 1988-08-02 The Regents Of The University Of California Human-human hybrid cell lines that produce antibodies against antigenic determinants on cancer cells
EP0183876A1 (en) * 1984-11-27 1986-06-11 The Board Of Trustees Of The Leland Stanford Junior University Monoclonal antibodies for endotoxin core and their use
US5106746A (en) * 1985-05-22 1992-04-21 E. I. Du Pont De Nemours And Company Process for the in vitro immunization of human splenocytes against tumor associated antigens
US5776093A (en) * 1985-07-05 1998-07-07 Immunomedics, Inc. Method for imaging and treating organs and tissues
JPH0655680B2 (ja) * 1985-10-26 1994-07-27 萩原 義秀 悪性腫瘍用ヒトモノクロナル抗体複合剤
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JPH0767388B2 (ja) * 1986-01-13 1995-07-26 三菱化学株式会社 抗体産生細胞株の樹立方法
WO1991009135A1 (en) * 1989-12-18 1991-06-27 Board Of Regents, The University Of Texas System Tumor-specific, cell surface-binding monoclonal antibodies
US5281710A (en) * 1990-08-01 1994-01-25 The Scripps Research Institute Dynemicin analogs: synthesis, methods of preparation and use
JPH04346792A (ja) * 1991-05-22 1992-12-02 Hagiwara Yoshihide 抗癌ヒトモノクローナル抗体のアミノ酸配列及びそれをコードするｄｎａ塩基配列
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Also Published As

Publication number Publication date
DE3382764D1 (de) 1994-12-22
FI840219A (fi) 1984-01-19
JPH0159878B2 (zh) 1989-12-20
ATE114189T1 (de) 1994-12-15
WO1983004313A1 (en) 1983-12-08
CZ280677B6 (cs) 1996-04-17
CZ356683A3 (en) 1995-11-15
EP0109441A4 (en) 1986-09-22
DK164510C (da) 1992-11-23
FI86077C (fi) 1992-07-10
ZA833686B (en) 1984-09-26
SK356683A3 (en) 1998-08-05
DE3382764T2 (de) 1995-03-16
DK25084A (da) 1984-01-20
JPS58201994A (ja) 1983-11-25
AU560595B2 (en) 1987-04-09
EP0109441A1 (en) 1984-05-30
AU1772983A (en) 1983-12-16
FI840219A0 (fi) 1984-01-19
HU190908B (en) 1986-12-28
JPS60501359A (ja) 1985-08-22
IN157982B (zh) 1986-08-09
DK25084D0 (da) 1984-01-20
EP0109441B1 (en) 1994-11-17
FI86077B (fi) 1992-03-31
DK164510B (da) 1992-07-06

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