SG11201509278XA - Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds - Google Patents

Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds

Info

Publication number
SG11201509278XA
SG11201509278XA SG11201509278XA SG11201509278XA SG11201509278XA SG 11201509278X A SG11201509278X A SG 11201509278XA SG 11201509278X A SG11201509278X A SG 11201509278XA SG 11201509278X A SG11201509278X A SG 11201509278XA SG 11201509278X A SG11201509278X A SG 11201509278XA
Authority
SG
Singapore
Prior art keywords
biomarkers
predicting
endometrial cancer
cancer subjects
assessing responsiveness
Prior art date
Application number
SG11201509278XA
Other languages
English (en)
Inventor
Yasuhiro Funahashi
Tadashi Kadowaki
Pallavi Sachdev
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of SG11201509278XA publication Critical patent/SG11201509278XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57442—Specifically defined cancers of the uterus and endometrial
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/515—Angiogenesic factors; Angiogenin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
SG11201509278XA 2013-05-14 2014-05-12 Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds SG11201509278XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361823034P 2013-05-14 2013-05-14
PCT/JP2014/063134 WO2014185540A1 (fr) 2013-05-14 2014-05-12 Biomarqueurs pour prédire et évaluer la réponse de sujets atteints de cancer de l'endomètre à des composés à base de lenvatinib

Publications (1)

Publication Number Publication Date
SG11201509278XA true SG11201509278XA (en) 2015-12-30

Family

ID=50877624

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201509278XA SG11201509278XA (en) 2013-05-14 2014-05-12 Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds

Country Status (14)

Country Link
US (1) US10517861B2 (fr)
EP (1) EP2997377B1 (fr)
JP (1) JP6411379B2 (fr)
KR (1) KR102204279B1 (fr)
CN (1) CN105264380B (fr)
AU (1) AU2014266223B2 (fr)
CA (1) CA2912219C (fr)
ES (1) ES2687968T3 (fr)
IL (1) IL242519B (fr)
MX (1) MX368099B (fr)
NZ (1) NZ714049A (fr)
RU (1) RU2658601C2 (fr)
SG (1) SG11201509278XA (fr)
WO (1) WO2014185540A1 (fr)

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RU2658601C2 (ru) 2013-05-14 2018-06-21 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Биомаркер для прогнозирования и оценки чувствительности субъектов с раком эндометрия к соединениям ленватиниба
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CA2978226A1 (fr) * 2015-03-04 2016-09-09 Merck Sharpe & Dohme Corp. Association d'un antagoniste de pd-1 et d'un inhibiteur des tyrosines kinases vegfr/fgfr/ret pour traiter le cancer
EP3304086B1 (fr) 2015-05-29 2020-12-23 Eisai R&D Management Co., Ltd. Méthode pour prédire la réactivité à une thérapie combinée avec du lenvatinib et de l'évérolimus
ES2886107T3 (es) 2015-06-16 2021-12-16 Prism Biolab Co Ltd Antineoplásico
WO2017181079A2 (fr) * 2016-04-15 2017-10-19 Genentech, Inc. Méthodes de surveillance et de traitement du cancer
WO2018160841A1 (fr) 2017-03-01 2018-09-07 Genentech, Inc. Procédés diagnostiques et thérapeutiques relatifs au cancer
WO2020070144A1 (fr) * 2018-10-04 2020-04-09 Synthon B.V. Formes cristallines et procédés de lenvatinib besylate
ES2939143T3 (es) * 2018-10-05 2023-04-19 Eisai R&D Man Co Ltd Biomarcadores para una politerapia que comprende lenvatinib y everolimus
CN113533544A (zh) * 2020-04-16 2021-10-22 先声药业有限公司 一种甲磺酸仑伐替尼的有关物质检测方法
CN114441764B (zh) * 2021-12-24 2022-09-27 广州市妇女儿童医疗中心 Angiogenin作为先天性巨结肠肠炎早期预测及诊断标志物的应用

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EP2997377A1 (fr) 2016-03-23
IL242519B (en) 2018-02-28
NZ714049A (en) 2020-05-29
CN105264380A (zh) 2016-01-20
CA2912219A1 (fr) 2014-11-20
ES2687968T3 (es) 2018-10-30
US20160089366A1 (en) 2016-03-31
KR20160009551A (ko) 2016-01-26
CA2912219C (fr) 2021-11-16
EP2997377B1 (fr) 2018-07-18
MX2015015605A (es) 2016-07-07
JP6411379B2 (ja) 2018-10-24
AU2014266223A1 (en) 2015-11-26
US10517861B2 (en) 2019-12-31
MX368099B (es) 2019-09-19
RU2658601C2 (ru) 2018-06-21
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CN105264380B (zh) 2017-09-05
JP2016522879A (ja) 2016-08-04

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