MX360254B - Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer. - Google Patents

Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer.

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Publication number
MX360254B
MX360254B MX2013010340A MX2013010340A MX360254B MX 360254 B MX360254 B MX 360254B MX 2013010340 A MX2013010340 A MX 2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A MX 360254 B MX360254 B MX 360254B
Authority
MX
Mexico
Prior art keywords
cancer
systemic
combination
local
composition
Prior art date
Application number
MX2013010340A
Other languages
English (en)
Other versions
MX2013010340A (es
Inventor
J Eagle Craig
Craig Dees H
A Wachter Eric
Singer Jamie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX2013010340A publication Critical patent/MX2013010340A/es
Publication of MX360254B publication Critical patent/MX360254B/es

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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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Abstract

La presente invención se refiere a una composición para uso en el tratamiento de cáncer, en donde la composición comprende una composición farmacéutica quimoablativa intralesión que comprende una solución acuosa a una concentración de 0.1% (p/v) o mayor de una xanteno halogenado a una sal fisiológicamente aceptable del xanteno halogenado, en donde el xanteno halogenado es rosa de bengala (4,5,6,7-tetracloro-2´,4´,5´,7´-tetrayodofluoresceína), en donde la composición está adaptada para ser administrable en una cantidad terapéuticamente efectiva y en combinación con una cantidad terapéuticamente efectiva de un agent anticáncer inmunomodulador sistémico, y en donde el agente anticáncer inmunomodulador sistémico comprende un anticuerpo anti-CTLA-4.
MX2013010340A 2011-03-10 2012-03-09 Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer. MX360254B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161451395P 2011-03-10 2011-03-10
PCT/US2012/028412 WO2012122444A1 (en) 2011-03-10 2012-03-09 Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer

Publications (2)

Publication Number Publication Date
MX2013010340A MX2013010340A (es) 2013-11-01
MX360254B true MX360254B (es) 2018-10-26

Family

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MX2013010340A MX360254B (es) 2011-03-10 2012-03-09 Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer.

Country Status (9)

Country Link
US (7) US9107887B2 (es)
EP (1) EP2710137B1 (es)
JP (2) JP6322413B2 (es)
KR (1) KR20140038382A (es)
CN (1) CN103476943A (es)
CA (1) CA2828940C (es)
ES (1) ES2699965T3 (es)
MX (1) MX360254B (es)
WO (1) WO2012122444A1 (es)

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