MX2013010340A - Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer. - Google Patents
Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer.Info
- Publication number
- MX2013010340A MX2013010340A MX2013010340A MX2013010340A MX2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A MX 2013010340 A MX2013010340 A MX 2013010340A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- combination
- systemic
- effective amount
- therapeutically effective
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 230000009885 systemic effect Effects 0.000 title abstract 3
- 230000002519 immonomodulatory effect Effects 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001834 xanthenyl group Chemical class C1=CC=CC=2OC3=CC=CC=C3C(C12)* 0.000 abstract 1
Classifications
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Un método para el tratamiento del cáncer que comprende la administración de una cantidad terapéuticamente efectiva de una composición farmacéutica quimioablativa dentro de una lesión, o variante de la composición, en combinación con una cantidad terapéuticamente efectiva de un agente anticáncer inmunomodulador sistémico. Un método adicional para el tratamiento del cáncer que comprende la administración de una cantidad terapéuticamente efectiva de una composición farmacéutica quimioablativa dentro de una lesión, o variante de la composición, en combinación con una cantidad terapéuticamente efectiva de un agente anticáncer sistémico dirigido. La presente invención está dirigida además a una composición farmacéutica para el tratamiento del cáncer. La composición farmacéutica quimioablativa dentro de una lesión puede comprender un agente quimioablativo de IL que comprende principalmente un xanteno halogenado.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161451395P | 2011-03-10 | 2011-03-10 | |
PCT/US2012/028412 WO2012122444A1 (en) | 2011-03-10 | 2012-03-09 | Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013010340A true MX2013010340A (es) | 2013-11-01 |
MX360254B MX360254B (es) | 2018-10-26 |
Family
ID=46798564
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013010340A MX360254B (es) | 2011-03-10 | 2012-03-09 | Combinacion de terapias inmunomoduladoras local y sistemica para tratamiento mejorado del cancer. |
Country Status (9)
Country | Link |
---|---|
US (7) | US9107887B2 (es) |
EP (1) | EP2710137B1 (es) |
JP (2) | JP6322413B2 (es) |
KR (1) | KR20140038382A (es) |
CN (1) | CN103476943A (es) |
CA (1) | CA2828940C (es) |
ES (1) | ES2699965T3 (es) |
MX (1) | MX360254B (es) |
WO (1) | WO2012122444A1 (es) |
Families Citing this family (109)
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EP1797881B1 (en) | 2004-09-17 | 2009-04-15 | Eisai R&D Management Co., Ltd. | Medicinal composition with improved stability and reduced gelation properties |
EP2281901B1 (en) * | 2005-08-02 | 2013-11-27 | Eisai R&D Management Co., Ltd. | Anti-tumour pharmaceutical composition with angiogenesis inhibitors |
US20090053236A1 (en) | 2005-11-07 | 2009-02-26 | Eisai R & D Management Co., Ltd. | USE OF COMBINATION OF ANTI-ANGIOGENIC SUBSTANCE AND c-kit KINASE INHIBITOR |
EP2036557B1 (en) * | 2006-05-18 | 2015-10-21 | Eisai R&D Management Co., Ltd. | Antitumor agent for thyroid cancer |
JP5319306B2 (ja) * | 2007-01-29 | 2013-10-16 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 未分化型胃癌治療用組成物 |
US8952035B2 (en) * | 2007-11-09 | 2015-02-10 | Eisai R&D Management Co., Ltd. | Combination of anti-angiogenic substance and anti-tumor platinum complex |
CN102958523B (zh) | 2010-06-25 | 2014-11-19 | 卫材R&D管理有限公司 | 使用具有激酶抑制作用的组合的抗肿瘤剂 |
EP2710137B1 (en) | 2011-03-10 | 2018-09-19 | Provectus Pharmatech, Inc. | A combination of rose bengal and anti-ctla4 antibody for use in the treatment of cancer |
WO2012144463A1 (ja) * | 2011-04-18 | 2012-10-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 腫瘍治療剤 |
US9945862B2 (en) | 2011-06-03 | 2018-04-17 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds |
PE20142406A1 (es) | 2012-05-04 | 2015-01-23 | Pfizer | Antigenos asociados a prostata y regimenes de inmunoterapia basados en vacuna |
CN104704002B (zh) * | 2012-08-30 | 2022-05-10 | 安姆根有限公司 | 使用单纯疱疹病毒和免疫检查点抑制剂治疗黑色素瘤的方法 |
BR112015009004A8 (pt) | 2012-12-21 | 2021-07-20 | Eisai R&D Man Co Ltd | forma amorfa de derivado de quinolina e método de produção da mesma |
TW201427681A (zh) * | 2013-01-07 | 2014-07-16 | Superlab Far East Ltd | 用空間構象改變的重組干擾素治療腫瘤的方法 |
KR20160002971A (ko) * | 2013-04-18 | 2016-01-08 | 틸트 바이오세러퓨틱스 오이 | 향상된 입양 세포 치료 |
MX368099B (es) | 2013-05-14 | 2019-09-19 | Eisai R&D Man Co Ltd | Biomarcadores para predecir y evaluar el grado de respuesta de sujetos con cancer de endometrio a compuestos de tipo lenvatinib. |
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US11071781B2 (en) | 2021-07-27 |
US20120263677A1 (en) | 2012-10-18 |
CN103476943A (zh) | 2013-12-25 |
CA2828940A1 (en) | 2012-09-13 |
US20150290318A1 (en) | 2015-10-15 |
EP2710137A1 (en) | 2014-03-26 |
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