SG11201505597SA - Methods for improved production of rebaudioside d and rebaudioside m - Google Patents
Methods for improved production of rebaudioside d and rebaudioside mInfo
- Publication number
- SG11201505597SA SG11201505597SA SG11201505597SA SG11201505597SA SG11201505597SA SG 11201505597S A SG11201505597S A SG 11201505597SA SG 11201505597S A SG11201505597S A SG 11201505597SA SG 11201505597S A SG11201505597S A SG 11201505597SA SG 11201505597S A SG11201505597S A SG 11201505597SA
- Authority
- SG
- Singapore
- Prior art keywords
- rebaudioside
- methods
- improved production
- production
- improved
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/36—Terpene glycosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Seasonings (AREA)
- Enzymes And Modification Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361761490P | 2013-02-06 | 2013-02-06 | |
| US201361886442P | 2013-10-03 | 2013-10-03 | |
| PCT/EP2014/052363 WO2014122227A2 (en) | 2013-02-06 | 2014-02-06 | Methods for improved production of rebaudioside d and rebaudioside m |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201505597SA true SG11201505597SA (en) | 2015-08-28 |
Family
ID=50064631
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201505597SA SG11201505597SA (en) | 2013-02-06 | 2014-02-06 | Methods for improved production of rebaudioside d and rebaudioside m |
| SG10201705926YA SG10201705926YA (en) | 2013-02-06 | 2014-02-06 | Methods for improved production of rebaudioside d and rebaudioside m |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201705926YA SG10201705926YA (en) | 2013-02-06 | 2014-02-06 | Methods for improved production of rebaudioside d and rebaudioside m |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9957540B2 (enExample) |
| EP (2) | EP2954058B1 (enExample) |
| JP (4) | JP6379112B2 (enExample) |
| KR (1) | KR20150115002A (enExample) |
| CN (2) | CN105051195B (enExample) |
| AU (4) | AU2014214004B2 (enExample) |
| CA (2) | CA2899276C (enExample) |
| MX (1) | MX369525B (enExample) |
| MY (2) | MY199452A (enExample) |
| SG (2) | SG11201505597SA (enExample) |
| WO (1) | WO2014122227A2 (enExample) |
Families Citing this family (117)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016130609A1 (en) | 2015-02-10 | 2016-08-18 | Purecircle Usa Inc. | Rebaudioside m biosynthetic production and recovery methods |
| US9107436B2 (en) | 2011-02-17 | 2015-08-18 | Purecircle Sdn Bhd | Glucosylated steviol glycoside as a flavor modifier |
| US10696706B2 (en) | 2010-03-12 | 2020-06-30 | Purecircle Usa Inc. | Methods of preparing steviol glycosides and uses of the same |
| CN105671108A (zh) | 2010-06-02 | 2016-06-15 | 沃维公司 | 甜菊糖苷的重组生产 |
| US11690391B2 (en) | 2011-02-17 | 2023-07-04 | Purecircle Sdn Bhd | Glucosylated steviol glycoside as a flavor modifier |
| US9771434B2 (en) | 2011-06-23 | 2017-09-26 | Purecircle Sdn Bhd | Products from stevia rebaudiana |
| EP2742142B2 (en) | 2011-08-08 | 2020-03-25 | Evolva SA | Recombinant production of steviol glycosides |
| JP6251669B2 (ja) | 2012-03-16 | 2017-12-20 | サントリーホールディングス株式会社 | ステビオール配糖体化酵素およびそれをコードする遺伝子 |
| ES2820518T3 (es) | 2012-03-27 | 2021-04-21 | Suntory Holdings Ltd | Método para producir glucósido de esteviol |
| US9752174B2 (en) | 2013-05-28 | 2017-09-05 | Purecircle Sdn Bhd | High-purity steviol glycosides |
| MX395285B (es) | 2012-05-22 | 2025-03-25 | Purecircle Sdn Bhd | Glucosidos de esteviol de alta pureza. |
| TW201402599A (zh) | 2012-05-30 | 2014-01-16 | Suntory Holdings Ltd | 甜菊糖苷糖苷轉化酵素及編碼該酵素之基因 |
| CA2899276C (en) * | 2013-02-06 | 2022-11-01 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| US10017804B2 (en) | 2013-02-11 | 2018-07-10 | Evolva Sa | Efficient production of steviol glycosides in recombinant hosts |
| US10689681B2 (en) * | 2013-05-31 | 2020-06-23 | Dsm Ip Assets B.V. | Microorganisms for diterpene production |
| US10952458B2 (en) | 2013-06-07 | 2021-03-23 | Purecircle Usa Inc | Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier |
| EP3003058B2 (en) | 2013-06-07 | 2023-06-28 | Purecircle Usa Inc. | Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier |
| WO2015007748A1 (en) * | 2013-07-15 | 2015-01-22 | Dsm Ip Assets B.V. | Diterpene production |
| EP3536697A1 (en) | 2013-07-31 | 2019-09-11 | DSM IP Assets B.V. | Recovery of steviol glycosides |
| CN103397064B (zh) | 2013-08-14 | 2015-04-15 | 苏州汉酶生物技术有限公司 | 一种酶法制备瑞鲍迪甙m的方法 |
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| MX2017001859A (es) | 2014-08-11 | 2017-04-11 | Evolva Sa | Produccion de glicosidos de esteviol en hospederos recombinantes. |
| EP3683315A1 (en) * | 2014-08-19 | 2020-07-22 | Purecircle SDN BHD | Method for preparing rebaudioside m |
| WO2016036578A1 (en) * | 2014-09-02 | 2016-03-10 | Purecircle Sdn Bhd | Stevia extracts |
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| US12677849B2 (en) | 2014-09-19 | 2026-07-14 | Purecircle Sdn. Bhd. | High-purity steviol glycosides |
| BR112017005656A2 (pt) | 2014-09-19 | 2018-07-31 | Purecircle Sdn Bhd | glicosídeos de esteviol de alta pureza |
| EP3197469B1 (en) | 2014-09-26 | 2023-08-09 | PureCircle USA Inc. | Stevia composition, production method and uses |
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| JP6251669B2 (ja) | 2012-03-16 | 2017-12-20 | サントリーホールディングス株式会社 | ステビオール配糖体化酵素およびそれをコードする遺伝子 |
| MX395285B (es) * | 2012-05-22 | 2025-03-25 | Purecircle Sdn Bhd | Glucosidos de esteviol de alta pureza. |
| WO2014048392A1 (zh) | 2012-09-29 | 2014-04-03 | 中国科学院上海生命科学研究院 | 利用微生物生产甜菊糖苷类化合物的方法 |
| EP2928321A1 (en) * | 2012-12-05 | 2015-10-14 | Evolva SA | Steviol glycoside compositions sensory properties |
| CA2899276C (en) | 2013-02-06 | 2022-11-01 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| US10017804B2 (en) * | 2013-02-11 | 2018-07-10 | Evolva Sa | Efficient production of steviol glycosides in recombinant hosts |
| US10689681B2 (en) | 2013-05-31 | 2020-06-23 | Dsm Ip Assets B.V. | Microorganisms for diterpene production |
| CN105247064A (zh) | 2013-05-31 | 2016-01-13 | 帝斯曼知识产权资产管理有限公司 | 细胞外的二萜生产 |
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| WO2015011209A1 (en) | 2013-07-23 | 2015-01-29 | Dsm Ip Assets B.V. | Diterpene production in yarrowia |
| EP3536697A1 (en) | 2013-07-31 | 2019-09-11 | DSM IP Assets B.V. | Recovery of steviol glycosides |
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| EP3042953A4 (en) | 2013-08-02 | 2017-07-12 | Suntory Holdings Limited | Method for using hexenol glycosyl transferase |
| CN103397064B (zh) | 2013-08-14 | 2015-04-15 | 苏州汉酶生物技术有限公司 | 一种酶法制备瑞鲍迪甙m的方法 |
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| JP2017528134A (ja) | 2014-09-09 | 2017-09-28 | エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． | 組み換え宿主におけるステビオールグリコシドの生産 |
| KR102557670B1 (ko) | 2014-10-03 | 2023-07-20 | 코나겐 인크. | 비칼로리 감미료 및 합성 방법 |
| CA3255837A1 (en) | 2015-03-16 | 2025-10-30 | Dsm Ip Assets B.V. | Udp-glycosyltransferases |
| CA2994288A1 (en) * | 2015-08-06 | 2017-02-09 | Cargill, Incorporated | Fermentation methods for producing steviol glycosides |
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