SE434638B - Nya terapeutiska verdefulla taurinderivat och deras framstellning - Google Patents

Nya terapeutiska verdefulla taurinderivat och deras framstellning

Info

Publication number
SE434638B
SE434638B SE8004261A SE8004261A SE434638B SE 434638 B SE434638 B SE 434638B SE 8004261 A SE8004261 A SE 8004261A SE 8004261 A SE8004261 A SE 8004261A SE 434638 B SE434638 B SE 434638B
Authority
SE
Sweden
Prior art keywords
formula
chloride
ethyl
effect
isopropyl
Prior art date
Application number
SE8004261A
Other languages
English (en)
Swedish (sv)
Other versions
SE8004261L (sv
Inventor
L H Andersen
L A I Hilden
Original Assignee
Lekemedelsfabriken Medica Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lekemedelsfabriken Medica Ab filed Critical Lekemedelsfabriken Medica Ab
Priority to SE8004261A priority Critical patent/SE434638B/sv
Priority to IL62824A priority patent/IL62824A/xx
Priority to IE1037/81A priority patent/IE51264B1/en
Priority to PT73061A priority patent/PT73061B/pt
Priority to ZA00813387A priority patent/ZA813387B/xx
Priority to CH725/82A priority patent/CH647505A5/de
Priority to JP56502071A priority patent/JPS57500877A/ja
Priority to DE19813152071 priority patent/DE3152071C2/de
Priority to AT0907681A priority patent/AT376206B/de
Priority to GB8212499A priority patent/GB2093457B/en
Priority to PCT/FI1981/000037 priority patent/WO1981003492A1/en
Priority to HU812299A priority patent/HU184871B/hu
Priority to NL8120217A priority patent/NL8120217A/nl
Priority to US06/342,018 priority patent/US4556673A/en
Priority to FR8110527A priority patent/FR2486077B1/fr
Priority to CS813955A priority patent/CS235088B2/cs
Priority to ES502761A priority patent/ES502761A0/es
Priority to DD81230575A priority patent/DD159427A5/de
Priority to BE0/205004A priority patent/BE889100A/fr
Priority to PL1981235510A priority patent/PL128574B1/pl
Priority to CA000379126A priority patent/CA1165322A/en
Priority to PL1981231531A priority patent/PL128321B1/pl
Priority to IT8122151A priority patent/IT8122151A0/it
Publication of SE8004261L publication Critical patent/SE8004261L/xx
Priority to NO82820213A priority patent/NO155840C/no
Priority to DK030082A priority patent/DK155521B/da
Priority to CS82940A priority patent/CS235091B2/cs
Priority to FI821650A priority patent/FI67214C/sv
Priority to SU823461553A priority patent/SU1097198A3/ru
Publication of SE434638B publication Critical patent/SE434638B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
SE8004261A 1980-06-06 1980-06-06 Nya terapeutiska verdefulla taurinderivat och deras framstellning SE434638B (sv)

Priority Applications (28)

Application Number Priority Date Filing Date Title
SE8004261A SE434638B (sv) 1980-06-06 1980-06-06 Nya terapeutiska verdefulla taurinderivat och deras framstellning
IL62824A IL62824A (en) 1980-06-06 1981-05-08 Phthalyltaurine derivatives,their preparation and pharmaceutical compositions comprising them
IE1037/81A IE51264B1 (en) 1980-06-06 1981-05-11 Taurine derivatives
PT73061A PT73061B (en) 1980-06-06 1981-05-20 Process for the preparation of new derivatives of taurina and its pharmaceutical use
ZA00813387A ZA813387B (en) 1980-06-06 1981-05-20 Chemical compounds,their production and their use in drugs
US06/342,018 US4556673A (en) 1980-06-06 1981-05-22 Use of phthalyltaurine sulfonamide derivatives in treating epilepsy and arrythmia
JP56502071A JPS57500877A (da) 1980-06-06 1981-05-22
DE19813152071 DE3152071C2 (de) 1980-06-06 1981-05-22 Taurinderivate, deren Herstellung und Verwendung in Arzneimitteln
AT0907681A AT376206B (de) 1980-06-06 1981-05-22 Verfahren zur herstellung von neuen taurinderivaten
GB8212499A GB2093457B (en) 1980-06-06 1981-05-22 Chemical compounds their production and their use in drugs
PCT/FI1981/000037 WO1981003492A1 (en) 1980-06-06 1981-05-22 Chemical compounds,their production,and their use in drugs
HU812299A HU184871B (en) 1980-06-06 1981-05-22 Process for preparing taurine derivatives
NL8120217A NL8120217A (da) 1980-06-06 1981-05-22
CH725/82A CH647505A5 (de) 1980-06-06 1981-05-22 Taurinderivate, verfahren zu deren herstellung und arzneimittel, welche diese verbindungen enthalten.
FR8110527A FR2486077B1 (da) 1980-06-06 1981-05-27
CS813955A CS235088B2 (en) 1980-06-06 1981-05-28 Method of new taurine derivatives production
DD81230575A DD159427A5 (de) 1980-06-06 1981-06-04 Verfahren zur herstellung von neuen taurinderivaten
BE0/205004A BE889100A (fr) 1980-06-06 1981-06-04 Derives de taurine, leur preparation et leur utilisation
ES502761A ES502761A0 (es) 1980-06-06 1981-06-04 Metodo de preparar nuevos derivados de taurina
PL1981235510A PL128574B1 (en) 1980-06-06 1981-06-05 Process for preparing novel derivatives of taurine
CA000379126A CA1165322A (en) 1980-06-06 1981-06-05 Phthalyltaurine sulfonamides
PL1981231531A PL128321B1 (en) 1980-06-06 1981-06-05 Process for preparing novel derivatives of taurine
IT8122151A IT8122151A0 (it) 1980-06-06 1981-06-05 Composti chimici, loro produzione e loro uso in medicinali.
NO82820213A NO155840C (no) 1980-06-06 1982-01-25 Analogifremgangsmaate for fremstilling av terapeutisk aktive taurin-derivater.
DK030082A DK155521B (da) 1980-06-06 1982-01-25 Analogifremgangsmaade til fremstilling af taurinderivater
CS82940A CS235091B2 (en) 1980-06-06 1982-02-11 Method of new taurine derivatives production
FI821650A FI67214C (fi) 1980-06-06 1982-05-11 Foerfarande foer framstaellning av nya terapeutiskt vaerdefulla taurinderivat
SU823461553A SU1097198A3 (ru) 1980-06-06 1982-07-05 Способ получени производных таурина

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8004261A SE434638B (sv) 1980-06-06 1980-06-06 Nya terapeutiska verdefulla taurinderivat och deras framstellning

Publications (2)

Publication Number Publication Date
SE8004261L SE8004261L (sv) 1981-12-07
SE434638B true SE434638B (sv) 1984-08-06

Family

ID=20341162

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8004261A SE434638B (sv) 1980-06-06 1980-06-06 Nya terapeutiska verdefulla taurinderivat och deras framstellning

Country Status (26)

Country Link
US (1) US4556673A (da)
JP (1) JPS57500877A (da)
AT (1) AT376206B (da)
BE (1) BE889100A (da)
CA (1) CA1165322A (da)
CH (1) CH647505A5 (da)
CS (2) CS235088B2 (da)
DD (1) DD159427A5 (da)
DE (1) DE3152071C2 (da)
DK (1) DK155521B (da)
ES (1) ES502761A0 (da)
FI (1) FI67214C (da)
FR (1) FR2486077B1 (da)
GB (1) GB2093457B (da)
HU (1) HU184871B (da)
IE (1) IE51264B1 (da)
IL (1) IL62824A (da)
IT (1) IT8122151A0 (da)
NL (1) NL8120217A (da)
NO (1) NO155840C (da)
PL (2) PL128574B1 (da)
PT (1) PT73061B (da)
SE (1) SE434638B (da)
SU (1) SU1097198A3 (da)
WO (1) WO1981003492A1 (da)
ZA (1) ZA813387B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE458606B (sv) * 1987-04-10 1989-04-17 Huhtamaeki Oy 2-ftalimidoetansulfon-n-arylamider och foerfarande foer framstaellning av dessa
US5801195A (en) * 1994-12-30 1998-09-01 Celgene Corporation Immunotherapeutic aryl amides
AR016384A1 (es) * 1997-07-30 2001-07-04 Smithkline Beecham Corp Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta.
US6020358A (en) * 1998-10-30 2000-02-01 Celgene Corporation Substituted phenethylsulfones and method of reducing TNFα levels
AU2006200033B8 (en) * 1998-10-30 2008-09-11 Celgene Corporation Substituted phenethylsulfones and methods of reducing TNF-alpha levels
US6667316B1 (en) 1999-11-12 2003-12-23 Celgene Corporation Pharmaceutically active isoindoline derivatives
US6326388B1 (en) 1999-12-21 2001-12-04 Celgene Corporation Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level
US6699899B1 (en) * 1999-12-21 2004-03-02 Celgene Corporation Substituted acylhydroxamic acids and method of reducing TNFα levels
US8030343B2 (en) * 2000-06-08 2011-10-04 Celgene Corporation Pharmaceutically active isoindoline derivatives
US7491634B2 (en) * 2006-04-28 2009-02-17 Asm International N.V. Methods for forming roughened surfaces and applications thereof
WO2003000654A1 (en) * 2001-06-26 2003-01-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Valproyltaurinamide derivatives as anticonvulsant and cns active agents
US7244759B2 (en) 2004-07-28 2007-07-17 Celgene Corporation Isoindoline compounds and methods of making and using the same
CN114539106B (zh) * 2022-03-15 2023-05-02 梯尔希（南京）药物研发有限公司 一种稳定同位素标记的牛磺酰胺盐酸盐的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2184279A (en) * 1937-11-27 1939-12-26 Squibb & Sons Inc Amino-aliphatic sulphonamides and process for preparing them
AT219039B (de) * 1959-05-27 1962-01-10 Geigy Ag J R Verfahren zur Herstellung von neuen Isoindolinderivaten
GB1254414A (en) * 1969-05-08 1971-11-24 Shun-Ichi Naito Novel aminoethanesulfonylamino derivatives and their production
US4093723A (en) * 1976-05-19 1978-06-06 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
ZA76757B (en) * 1975-03-18 1977-01-26 Smithkline Corp New cephalosporin compounds
US4048311A (en) * 1976-01-08 1977-09-13 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

Also Published As

Publication number Publication date
DE3152071T1 (de) 1983-10-20
ES8203342A1 (es) 1982-04-01
CS235088B2 (en) 1985-04-16
ZA813387B (en) 1982-06-30
NL8120217A (da) 1982-08-02
WO1981003492A1 (en) 1981-12-10
FR2486077B1 (da) 1988-08-12
DD159427A5 (de) 1983-03-09
FI67214B (fi) 1984-10-31
IE51264B1 (en) 1986-11-26
NO155840C (no) 1987-06-10
PL128321B1 (en) 1984-01-31
SU1097198A3 (ru) 1984-06-07
FI821650L (fi) 1982-05-11
PT73061B (en) 1982-07-01
NO155840B (no) 1987-03-02
IL62824A (en) 1984-07-31
GB2093457B (en) 1984-03-21
CS235091B2 (en) 1985-04-16
US4556673A (en) 1985-12-03
HU184871B (en) 1984-10-29
SE8004261L (sv) 1981-12-07
IT8122151A0 (it) 1981-06-05
FR2486077A1 (da) 1982-01-08
DK155521B (da) 1989-04-17
FI67214C (fi) 1985-02-11
DK30082A (da) 1982-01-25
CH647505A5 (de) 1985-01-31
PT73061A (en) 1981-06-01
IL62824A0 (en) 1981-07-31
CA1165322A (en) 1984-04-10
DE3152071C2 (de) 1989-06-15
BE889100A (fr) 1981-12-04
ES502761A0 (es) 1982-04-01
ATA907681A (de) 1984-03-15
IE811037L (en) 1981-12-06
GB2093457A (en) 1982-09-02
PL128574B1 (en) 1984-02-29
JPS57500877A (da) 1982-05-20
PL235510A1 (da) 1982-11-22
PL231531A1 (da) 1982-08-30
FI821650A0 (fi) 1982-05-11
AT376206B (de) 1984-10-25
NO820213L (no) 1982-01-25

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