RU95105587A - Оптически чистые соединения пиридинилметил сульфинил-1н-бензимидазола, их соли, способы получения, фармкомпозиция, способ лечения - Google Patents

Оптически чистые соединения пиридинилметил сульфинил-1н-бензимидазола, их соли, способы получения, фармкомпозиция, способ лечения

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Publication number
RU95105587A
RU95105587A RU95105587/04A RU95105587A RU95105587A RU 95105587 A RU95105587 A RU 95105587A RU 95105587/04 A RU95105587/04 A RU 95105587/04A RU 95105587 A RU95105587 A RU 95105587A RU 95105587 A RU95105587 A RU 95105587A
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RU
Russia
Prior art keywords
sulfinyl
benzimidazole
compounds
methoxy
synthesis
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RU95105587/04A
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English (en)
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RU2137766C1 (ru
Inventor
Леннарт Линдберг Пер
Se]
Вон Унге Сверкер
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Астра Актиеболаг (SE)
Астра Актиеболаг
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20390088&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU95105587(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Астра Актиеболаг (SE), Астра Актиеболаг filed Critical Астра Актиеболаг (SE)
Publication of RU95105587A publication Critical patent/RU95105587A/ru
Application granted granted Critical
Publication of RU2137766C1 publication Critical patent/RU2137766C1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)

Abstract

Новые оптически чистые соединения Na, Mg , Li, K, Ca и N(R)соли (+)-5-метокси-2-[[(4-метокси-3,5-диметил-2-пиридинил)метил] сульфинил] -1Н-бензимидазола или (-)-5-метокси-2-[[(4- метокси-3,5 -диметил-2-пиридинил)-метил] сульфинил]- 1Н-бензимидазола, в которых R представляет алкил с 1 - 4 углеродными атомами, способ их получения и фармацевтические препараты включающие соединения в качестве активных ингредиентов, равно как использование соединений в фармацевтических препаратах и промежуточные продукты полученные при приготовлении соединений.

Claims (1)

  1. Новые оптически чистые соединения Na+, Mg2 +, Li+, K+, Ca2 + и N+ (R)4 соли (+)-5-метокси-2-[[(4-метокси-3,5-диметил-2-пиридинил)метил] сульфинил] -1Н-бензимидазола или (-)-5-метокси-2-[[(4- метокси-3,5 -диметил-2-пиридинил)-метил] сульфинил]- 1Н-бензимидазола, в которых R представляет алкил с 1 - 4 углеродными атомами, способ их получения и фармацевтические препараты включающие соединения в качестве активных ингредиентов, равно как использование соединений в фармацевтических препаратах и промежуточные продукты полученные при приготовлении соединений.
RU95105587A 1993-05-28 1994-05-27 Оптически чистые na+, mg2+, li+, k+ или са2+ соли (-)-5-метокси-2[[(4-метокси-3,5-диметил-2-пиридинил)метил] сульфинил]-1h-бензимидазола, способ их получения, фармкомпозиция на их основе и промежуточное соединение RU2137766C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE19939301830A SE9301830D0 (sv) 1993-05-28 1993-05-28 New compounds
SE9301830-7 1993-05-28
PCT/SE1994/000509 WO1994027988A1 (en) 1993-05-28 1994-05-27 Optically pure salts of pyridinylmethyl sulfinyl-ih-benzimidazole compounds

Publications (2)

Publication Number Publication Date
RU95105587A true RU95105587A (ru) 1996-10-27
RU2137766C1 RU2137766C1 (ru) 1999-09-20

Family

ID=20390088

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95105587A RU2137766C1 (ru) 1993-05-28 1994-05-27 Оптически чистые na+, mg2+, li+, k+ или са2+ соли (-)-5-метокси-2[[(4-метокси-3,5-диметил-2-пиридинил)метил] сульфинил]-1h-бензимидазола, способ их получения, фармкомпозиция на их основе и промежуточное соединение

Country Status (43)

Country Link
US (5) US5693818A (ru)
EP (3) EP1020460B1 (ru)
JP (3) JP3549111B2 (ru)
KR (1) KR100337274B1 (ru)
CN (2) CN1055469C (ru)
AT (1) ATE197452T1 (ru)
CA (2) CA2337581A1 (ru)
CL (1) CL2009000805A1 (ru)
CY (1) CY2224B1 (ru)
CZ (1) CZ287876B6 (ru)
DE (4) DE652872T1 (ru)
DK (3) DK1020460T3 (ru)
DZ (1) DZ1785A1 (ru)
EE (1) EE03157B1 (ru)
ES (3) ES2326404T3 (ru)
FI (2) FI117755B (ru)
GR (2) GR970300012T1 (ru)
HK (3) HK1008330A1 (ru)
HR (1) HRP940307B1 (ru)
HU (1) HU226824B1 (ru)
IL (1) IL109684A (ru)
IS (1) IS1854B (ru)
LT (1) LT3287B (ru)
LU (1) LU91870I2 (ru)
LV (1) LV11034B (ru)
MA (1) MA23210A1 (ru)
MY (1) MY121192A (ru)
NO (2) NO307378B1 (ru)
NZ (1) NZ266915A (ru)
PL (1) PL178994B1 (ru)
PT (3) PT1020461E (ru)
RU (1) RU2137766C1 (ru)
SA (2) SA94140756B1 (ru)
SE (1) SE9301830D0 (ru)
SG (1) SG49283A1 (ru)
SI (2) SI9420002B (ru)
SK (1) SK282524B6 (ru)
TN (1) TNSN94058A1 (ru)
TW (1) TW389761B (ru)
UA (1) UA60289C2 (ru)
WO (1) WO1994027988A1 (ru)
YU (1) YU49065B (ru)
ZA (1) ZA943557B (ru)

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