NO960268L - Nye dialkoksypyridinylbenzimidazolderivater - Google Patents

Nye dialkoksypyridinylbenzimidazolderivater

Info

Publication number
NO960268L
NO960268L NO960268A NO960268A NO960268L NO 960268 L NO960268 L NO 960268L NO 960268 A NO960268 A NO 960268A NO 960268 A NO960268 A NO 960268A NO 960268 L NO960268 L NO 960268L
Authority
NO
Norway
Prior art keywords
compounds
methyl
new
dialkoxypyridinylbenzimidazole
derivatives
Prior art date
Application number
NO960268A
Other languages
English (en)
Other versions
NO960268D0 (no
Inventor
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Per Oskar Sverker Von Unge
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of NO960268L publication Critical patent/NO960268L/no
Publication of NO960268D0 publication Critical patent/NO960268D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Nye optisk rene forbindelser, dvs de enantiomere enkeltforbindelsene (+)-5- karbometoksy-6-metyl-2-[[(3,4-dimetoksy-2-pyridinyl)metyl]sulfmyl]-l-[mandel- oyloksymetyl]-! H-benzimidazol og (-)-5-karbometoksy-6-metyl-2-[[(3,4-dimetoksy-2- pyridinyl)metyl]sulfinyl]-1 -[mandeloyloksymetyl]-1 H-benzimidazol eller et terapeutisk akseptabelt salt derav, slik som Na+, Mg2+, Li+, K+, Ca2+og N+(R)4 salter, hvor R er en alkylgruppe med 1-4 karbonatomer, fremgangsmåter for fremstilling derav og farma- søytiske preparater inneholdende forbindelsene som aktive bestanddeler, anvendelse av forbindelsene i farmasøytiske preparater samt mellomprodukter oppnådd ved frem- ' stilling av forbindelsene.
NO960268A 1994-05-27 1996-01-23 Nye dialkoksypyridinylbenzimidazolderivater NO960268D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25617194A 1994-05-27 1994-05-27
SE9400511 1994-05-27
PCT/SE1995/000519 WO1995032959A1 (en) 1994-05-27 1995-05-11 Novel dialkoxy-pyridinyl-benzimidazole derivatives

Publications (2)

Publication Number Publication Date
NO960268L true NO960268L (no) 1996-01-23
NO960268D0 NO960268D0 (no) 1996-01-23

Family

ID=20392945

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960268A NO960268D0 (no) 1994-05-27 1996-01-23 Nye dialkoksypyridinylbenzimidazolderivater

Country Status (18)

Country Link
EP (1) EP0712401A1 (no)
JP (1) JPH09504557A (no)
CN (1) CN1128997A (no)
AU (1) AU2633095A (no)
BR (1) BR9506235A (no)
CA (1) CA2166988A1 (no)
CZ (1) CZ24396A3 (no)
EE (1) EE9600011A (no)
FI (1) FI960367A0 (no)
HU (1) HU9600005D0 (no)
IL (1) IL113604A0 (no)
IS (1) IS4321A (no)
MA (1) MA23563A1 (no)
NO (1) NO960268D0 (no)
PL (1) PL312692A1 (no)
TN (1) TNSN95062A1 (no)
WO (1) WO1995032959A1 (no)
ZA (1) ZA954125B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9423968D0 (en) * 1994-11-28 1995-01-11 Astra Ab Resolution
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
IL142629A0 (en) * 1998-11-18 2002-03-10 Astra Ab Improved chemical process and pharmaceutical formulation
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP2486910A3 (en) 2006-10-27 2012-08-22 The Curators Of The University Of Missouri Multi-chambered apparatus comprising a dispenser head
EP2252274A4 (en) 2008-02-20 2011-05-11 Univ Missouri COMPOSITION COMPRISING A COMBINATION OF OMEPRAZOLE AND LANSOPRAZOLE, AND A BUFFER AGENT, AND METHODS OF USING THE SAME
CA2736547C (en) 2008-09-09 2016-11-01 Pozen Inc. Method for delivering a pharmaceutical composition to patient in need thereof
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
MX2014007935A (es) 2011-12-28 2014-11-14 Pozen Inc Composiciones y metodos mejorados para el suministro de omeprazol y de acido acetilsalicilico.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL166209B1 (pl) * 1990-06-20 1995-04-28 Astra Ab Sposób wytwarzania nowych pochodnych benzimidazolu PL
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung

Also Published As

Publication number Publication date
CZ24396A3 (en) 1996-06-12
TNSN95062A1 (fr) 1996-02-06
WO1995032959A1 (en) 1995-12-07
FI960367A (fi) 1996-01-26
CN1128997A (zh) 1996-08-14
PL312692A1 (en) 1996-05-13
ZA954125B (en) 1995-11-27
AU2633095A (en) 1995-12-21
MA23563A1 (fr) 1995-12-31
CA2166988A1 (en) 1995-12-07
IL113604A0 (en) 1995-08-31
HU9600005D0 (en) 1996-03-28
JPH09504557A (ja) 1997-05-06
EE9600011A (et) 1996-04-15
IS4321A (is) 1996-01-17
BR9506235A (pt) 1997-08-12
FI960367A0 (fi) 1996-01-26
NO960268D0 (no) 1996-01-23
EP0712401A1 (en) 1996-05-22

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