BR9506235A - Compostos enanciométricos únicos uso dos mesmos processos para sua preparação e de(+)-e-(-)-5-carbometoxi-6-metail-2-((3,4-dimetoxi-2-piridinil)metil )1-h-benzimidazol ou seu sal de sódio em suas for mas cristalinas para inibição de secreção de ácido gástrico e para o tratamento de doenças inflamatórias gastrointestinais e preparação farmacêutica - Google Patents

Compostos enanciométricos únicos uso dos mesmos processos para sua preparação e de(+)-e-(-)-5-carbometoxi-6-metail-2-((3,4-dimetoxi-2-piridinil)metil )1-h-benzimidazol ou seu sal de sódio em suas for mas cristalinas para inibição de secreção de ácido gástrico e para o tratamento de doenças inflamatórias gastrointestinais e preparação farmacêutica

Info

Publication number
BR9506235A
BR9506235A BR9506235A BR9506235A BR9506235A BR 9506235 A BR9506235 A BR 9506235A BR 9506235 A BR9506235 A BR 9506235A BR 9506235 A BR9506235 A BR 9506235A BR 9506235 A BR9506235 A BR 9506235A
Authority
BR
Brazil
Prior art keywords
preparation
enanciometric
metail
carbomethoxy
benzimidazole
Prior art date
Application number
BR9506235A
Other languages
English (en)
Inventor
Per Lennart Lindberg
Per Oskar Sverker Von Unge
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of BR9506235A publication Critical patent/BR9506235A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BR9506235A 1994-05-27 1995-05-11 Compostos enanciométricos únicos uso dos mesmos processos para sua preparação e de(+)-e-(-)-5-carbometoxi-6-metail-2-((3,4-dimetoxi-2-piridinil)metil )1-h-benzimidazol ou seu sal de sódio em suas for mas cristalinas para inibição de secreção de ácido gástrico e para o tratamento de doenças inflamatórias gastrointestinais e preparação farmacêutica BR9506235A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9400511 1994-05-27
PCT/SE1995/000519 WO1995032959A1 (en) 1994-05-27 1995-05-11 Novel dialkoxy-pyridinyl-benzimidazole derivatives

Publications (1)

Publication Number Publication Date
BR9506235A true BR9506235A (pt) 1997-08-12

Family

ID=20392945

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9506235A BR9506235A (pt) 1994-05-27 1995-05-11 Compostos enanciométricos únicos uso dos mesmos processos para sua preparação e de(+)-e-(-)-5-carbometoxi-6-metail-2-((3,4-dimetoxi-2-piridinil)metil )1-h-benzimidazol ou seu sal de sódio em suas for mas cristalinas para inibição de secreção de ácido gástrico e para o tratamento de doenças inflamatórias gastrointestinais e preparação farmacêutica

Country Status (18)

Country Link
EP (1) EP0712401A1 (pt)
JP (1) JPH09504557A (pt)
CN (1) CN1128997A (pt)
AU (1) AU2633095A (pt)
BR (1) BR9506235A (pt)
CA (1) CA2166988A1 (pt)
CZ (1) CZ24396A3 (pt)
EE (1) EE9600011A (pt)
FI (1) FI960367A0 (pt)
HU (1) HU9600005D0 (pt)
IL (1) IL113604A0 (pt)
IS (1) IS4321A (pt)
MA (1) MA23563A1 (pt)
NO (1) NO960268L (pt)
PL (1) PL312692A1 (pt)
TN (1) TNSN95062A1 (pt)
WO (1) WO1995032959A1 (pt)
ZA (1) ZA954125B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9423970D0 (en) * 1994-11-28 1995-01-11 Astra Ab Oxidation
GB9423968D0 (en) * 1994-11-28 1995-01-11 Astra Ab Resolution
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
ES2222754T3 (es) * 1998-11-18 2005-02-01 Astrazeneca Ab Procedimiento quimico mejorado, y formulacion farmaceutica.
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2008057802A2 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
CN101980700A (zh) 2008-02-20 2011-02-23 密苏里大学董事会 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法
CA2736547C (en) 2008-09-09 2016-11-01 Pozen Inc. Method for delivering a pharmaceutical composition to patient in need thereof
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
UA115139C2 (uk) 2011-12-28 2017-09-25 Поузен Інк. Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69131627T2 (de) * 1990-06-20 2000-04-27 Astra Ab Soedertaelje Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung

Also Published As

Publication number Publication date
WO1995032959A1 (en) 1995-12-07
ZA954125B (en) 1995-11-27
CN1128997A (zh) 1996-08-14
PL312692A1 (en) 1996-05-13
EE9600011A (et) 1996-04-15
EP0712401A1 (en) 1996-05-22
IS4321A (is) 1996-01-17
NO960268D0 (no) 1996-01-23
HU9600005D0 (en) 1996-03-28
CA2166988A1 (en) 1995-12-07
MA23563A1 (fr) 1995-12-31
AU2633095A (en) 1995-12-21
NO960268L (no) 1996-01-23
JPH09504557A (ja) 1997-05-06
CZ24396A3 (en) 1996-06-12
FI960367A (fi) 1996-01-26
TNSN95062A1 (fr) 1996-02-06
IL113604A0 (en) 1995-08-31
FI960367A0 (fi) 1996-01-26

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Legal Events

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FA10 Dismissal: dismissal - article 33 of industrial property law