ATE198751T1 - Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen - Google Patents

Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen

Info

Publication number
ATE198751T1
ATE198751T1 AT96931039T AT96931039T ATE198751T1 AT E198751 T1 ATE198751 T1 AT E198751T1 AT 96931039 T AT96931039 T AT 96931039T AT 96931039 T AT96931039 T AT 96931039T AT E198751 T1 ATE198751 T1 AT E198751T1
Authority
AT
Austria
Prior art keywords
azoderivates
treatment
inflammatory bowel
bowel disease
aminosalicylic acid
Prior art date
Application number
AT96931039T
Other languages
English (en)
Inventor
Elena Carceller
Pere J Jimenez
Jordi Salas
Carmen Almansa
Javier Bartroli
Manel Merlos
Marta Giral
Dolors Balsa
Rosa Ferrando
Julian Garcia-Rafanell
Javier Forn
Original Assignee
Uriach & Cia Sa J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES9501752A external-priority patent/ES2106682B1/es
Priority claimed from ES9501967A external-priority patent/ES2104513B1/es
Application filed by Uriach & Cia Sa J filed Critical Uriach & Cia Sa J
Application granted granted Critical
Publication of ATE198751T1 publication Critical patent/ATE198751T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT96931039T 1995-09-08 1996-09-06 Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen ATE198751T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES9501752A ES2106682B1 (es) 1995-09-08 1995-09-08 Nuevos derivados azo del acido 5-aminosalicilico.
ES9501967A ES2104513B1 (es) 1995-10-11 1995-10-11 Nuevos derivados del acido 5-aminosalicilico.
PCT/EP1996/003921 WO1997009329A1 (en) 1995-09-08 1996-09-06 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease

Publications (1)

Publication Number Publication Date
ATE198751T1 true ATE198751T1 (de) 2001-02-15

Family

ID=26154915

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96931039T ATE198751T1 (de) 1995-09-08 1996-09-06 Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen

Country Status (17)

Country Link
US (1) US5747477A (de)
EP (1) EP0790998B1 (de)
JP (1) JP4115522B2 (de)
KR (1) KR100481300B1 (de)
AR (1) AR004198A1 (de)
AT (1) ATE198751T1 (de)
AU (1) AU6987596A (de)
BR (1) BR9606628A (de)
CA (1) CA2204747C (de)
DE (1) DE69611598T2 (de)
DK (1) DK0790998T3 (de)
ES (1) ES2155621T3 (de)
GR (1) GR3035622T3 (de)
MX (1) MX9702919A (de)
NO (1) NO308850B1 (de)
PT (1) PT790998E (de)
WO (1) WO1997009329A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6958324B2 (en) * 1998-12-02 2005-10-25 Inotek Pharmaceuticals Corporation Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease
ES2165803B1 (es) * 2000-04-10 2003-09-16 Uriach & Cia Sa J Nueva sal de un derivado azo del acido 5-aminosalicilico
AU2001268607A1 (en) 2000-06-21 2002-01-02 Bristol-Myers Squibb Company Piperidine amides as modulators of chemokine receptor activity
AU8531101A (en) * 2000-08-29 2002-03-13 Nobex Corp Immunoregulatory compounds and derivatives and methods of treating diseases therewith
US8048924B2 (en) * 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
US20030119792A1 (en) * 2001-09-28 2003-06-26 Roca Manuel Merlos Method of inhibiting the production and/or effects of intestinal pro-inflammatory cytokines, prostaglandins and others
DK1773767T3 (en) 2004-07-07 2016-03-21 Biocon Ltd Synthesis of azo bound in immune regulatory relations
US7741359B2 (en) 2005-05-27 2010-06-22 Antibe Therapeutics Inc. Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs
US7498355B2 (en) 2005-05-27 2009-03-03 Antibe Therapeutics Inc. Derivatives of 4- or 5-aminosalicylic acid
WO2006125293A1 (en) 2005-05-27 2006-11-30 Antibe Therapeutics Inc. Derivatives of 4- or 5-aminosalicylic acid
JP5421098B2 (ja) 2006-06-06 2014-02-19 ジーアイケア ファーマ インク. トリメブチン及びn−脱メチル化トリメブチンの塩類
US7645801B2 (en) 2007-01-29 2010-01-12 Alaven Pharmaceutical Llc Reduced irritant enema for treatment of inflammatory bowel disease (IBD)
CN105566153B (zh) * 2014-10-14 2019-05-31 中国医学科学院药物研究所 偶氮苯衍生物及其制法和药物组合物与用途
KR102173168B1 (ko) 2018-06-19 2020-11-03 주식회사 엠디헬스케어 류코노스톡속 균주를 포함하는 장 기능 개선용 조성물
EP3837993A4 (de) 2018-06-19 2022-04-20 Coenbio Co., Ltd. Zusammensetzung zur verbesserung der darmfunktion mit leuconostoc-sp.-stamm

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2396145A (en) * 1940-12-14 1946-03-05 Pharmscia Ab Heterocyclic sulphonamido azo compounds
US4312806A (en) * 1981-03-02 1982-01-26 G. D. Searle & Co. Method and compounds for treating inflammatory bowel disease
IE70217B1 (en) * 1990-08-15 1996-10-30 British Bio Technology Benzimidazole derivatives process for their preparation and application
GB9202791D0 (en) * 1992-02-11 1992-03-25 British Bio Technology Compounds
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.

Also Published As

Publication number Publication date
WO1997009329A1 (en) 1997-03-13
BR9606628A (pt) 1997-09-30
JPH11501939A (ja) 1999-02-16
KR100481300B1 (ko) 2005-07-29
AR004198A1 (es) 1998-11-04
NO308850B1 (no) 2000-11-06
MX9702919A (es) 1998-04-30
PT790998E (pt) 2001-04-30
KR970707125A (ko) 1997-12-01
NO972113L (no) 1997-05-07
DE69611598T2 (de) 2001-06-07
AU6987596A (en) 1997-03-27
US5747477A (en) 1998-05-05
EP0790998B1 (de) 2001-01-17
GR3035622T3 (en) 2001-06-29
CA2204747A1 (en) 1997-03-13
CA2204747C (en) 2009-05-05
NO972113D0 (no) 1997-05-07
ES2155621T3 (es) 2001-05-16
DE69611598D1 (de) 2001-02-22
EP0790998A1 (de) 1997-08-27
DK0790998T3 (da) 2001-02-05
JP4115522B2 (ja) 2008-07-09

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