ES2106682B1 - Nuevos derivados azo del acido 5-aminosalicilico. - Google Patents

Nuevos derivados azo del acido 5-aminosalicilico.

Info

Publication number
ES2106682B1
ES2106682B1 ES9501752A ES9501752A ES2106682B1 ES 2106682 B1 ES2106682 B1 ES 2106682B1 ES 9501752 A ES9501752 A ES 9501752A ES 9501752 A ES9501752 A ES 9501752A ES 2106682 B1 ES2106682 B1 ES 2106682B1
Authority
ES
Spain
Prior art keywords
alkyl
cyclloalkyl
aminosalicylic acid
aryl
new azo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9501752A
Other languages
English (en)
Other versions
ES2106682A1 (es
Inventor
Carmen Almansa
Javier Bartroli
Manel Merlos
Marta Giral
Dolors Balsa
Rosa Ferrando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noucor Health SA
Original Assignee
J Uriach y Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES9501752A priority Critical patent/ES2106682B1/es
Application filed by J Uriach y Cia SA filed Critical J Uriach y Cia SA
Priority to US08/836,125 priority patent/US5747477A/en
Priority to PCT/EP1996/003921 priority patent/WO1997009329A1/en
Priority to KR1019970703002A priority patent/KR100481300B1/ko
Priority to JP51087597A priority patent/JP4115522B2/ja
Priority to MX9702919A priority patent/MX9702919A/es
Priority to CA002204747A priority patent/CA2204747C/en
Priority to EP96931039A priority patent/EP0790998B1/en
Priority to DK96931039T priority patent/DK0790998T3/da
Priority to AU69875/96A priority patent/AU6987596A/en
Priority to AT96931039T priority patent/ATE198751T1/de
Priority to BR9606628A priority patent/BR9606628A/pt
Priority to DE69611598T priority patent/DE69611598T2/de
Priority to ARP960104275A priority patent/AR004198A1/es
Priority to ES96931039T priority patent/ES2155621T3/es
Priority to PT96931039T priority patent/PT790998E/pt
Priority to NO972113A priority patent/NO308850B1/no
Publication of ES2106682A1 publication Critical patent/ES2106682A1/es
Publication of ES2106682B1 publication Critical patent/ES2106682B1/es
Application granted granted Critical
Priority to GR20010400467T priority patent/GR3035622T3/el
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

COMPUESTOS DE FORMULA I, EN DONDE M REPRESENTA 1 O 2; R1 REPRESENTA C1-4 ALQUILO O C3-7 CICLOALQUILO; A, B Y C REPRESENTAN CR2, DONDE CADA R2 REPRESENTA HIDROGENO O C1-4 ALQUILO; A REPRESENTA -CO-, -SO2-, -NHCO- O -OCO-; B REPRESENTA UN GRUPO (I), (II), (III), (IV) O (V); N REPRESENTA 0-3; P REPRESENTA 0 O 1; R3 REPRESENTA HIDROGENO, C1-4 ALQUILO, C1-4 HALOALQUILO, C3-7 CICLOALQUILO, C1-4 ALCOXI-C1-4 ALQUILO O ARILO; R4 REPRESENTA HIDROGENO, C1-4 ALQUILO, -COOR5 O -CONR5R6, -NR5R6, -NR7C (=O) OR5, -NR7C (=O) R5, -NR7C (=O) NR5R6 O -NR7SO2R5; R5 REPRESENTA C1-4 ALQUILO, ARILO O ARIL C1-4 ALQUILO; R6 Y R7 REPRESENTAN HIDROGENO O C1-4 ALQUILO; Z REPRESENTA -OC(=O)-, -C(=O)-, -NR6C (=O)- O -SO2-; R8 REPRESENTA ARILO; R9 REPRESENTA C1-4 ALQUILO, C3-7 CICLOALQUILO, -C (=O) OR5, -C(=O)R5, -C(=O) NR5R6, O -SO2R5; Y R10 REPRESENTA C1-4 ALQUILO, C3-7 CICLOALQUILO, ARILO, O ARIL-C1-4 ALQUILO.
ES9501752A 1995-09-08 1995-09-08 Nuevos derivados azo del acido 5-aminosalicilico. Expired - Fee Related ES2106682B1 (es)

Priority Applications (18)

Application Number Priority Date Filing Date Title
ES9501752A ES2106682B1 (es) 1995-09-08 1995-09-08 Nuevos derivados azo del acido 5-aminosalicilico.
DE69611598T DE69611598T2 (de) 1995-09-08 1996-09-06 Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen
PCT/EP1996/003921 WO1997009329A1 (en) 1995-09-08 1996-09-06 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease
JP51087597A JP4115522B2 (ja) 1995-09-08 1996-09-06 新規な５−アミノサリチル酸のアゾ誘導体
MX9702919A MX9702919A (es) 1995-09-08 1996-09-06 Derivados azo del acido 5-aminosalicilico para el tratameitno de la enfermedad inflamatoria intestinal.
CA002204747A CA2204747C (en) 1995-09-08 1996-09-06 New azo derivatives of 5-aminosalicylic acid
EP96931039A EP0790998B1 (en) 1995-09-08 1996-09-06 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease
DK96931039T DK0790998T3 (da) 1995-09-08 1996-09-06 Azo-derivater af 5-aminosalicylsyre til behandling af inflammatorisk tarmsygdom
ARP960104275A AR004198A1 (es) 1995-09-08 1996-09-06 Un compuesto azo del acido 5-aminosalicilico y procedimiento para preparar el mismo
AT96931039T ATE198751T1 (de) 1995-09-08 1996-09-06 Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen
US08/836,125 US5747477A (en) 1995-09-08 1996-09-06 Azo derivatives of 5-aminosalicylic acid
KR1019970703002A KR100481300B1 (ko) 1995-09-08 1996-09-06 염증성장질환치료용의5-아미노살리실산의아조유도체
AU69875/96A AU6987596A (en) 1995-09-08 1996-09-06 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease
ES96931039T ES2155621T3 (es) 1995-09-08 1996-09-06 Derivados azo del acido 5-aminosalicilico para el tratamiento de la enfermedad inflamatoria intestinal.
PT96931039T PT790998E (pt) 1995-09-08 1996-09-06 Derivados azo do acido 5-aminosalicilico para o tratamento da doenca inflamatoria dos intestinos
BR9606628A BR9606628A (pt) 1995-09-08 1996-09-06 Novos derivados azo de ácido 5-aminosalicílico
NO972113A NO308850B1 (no) 1995-09-08 1997-05-07 Nye azoderivater av 5-aminosalicylsyre, anvendelse av disse og farmasøytisk preparat inneholdende dem
GR20010400467T GR3035622T3 (en) 1995-09-08 2001-03-23 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9501752A ES2106682B1 (es) 1995-09-08 1995-09-08 Nuevos derivados azo del acido 5-aminosalicilico.

Publications (2)

Publication Number Publication Date
ES2106682A1 ES2106682A1 (es) 1997-11-01
ES2106682B1 true ES2106682B1 (es) 1998-07-01

Family

ID=8291526

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9501752A Expired - Fee Related ES2106682B1 (es) 1995-09-08 1995-09-08 Nuevos derivados azo del acido 5-aminosalicilico.

Country Status (1)

Country Link
ES (1) ES2106682B1 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312806A (en) * 1981-03-02 1982-01-26 G. D. Searle & Co. Method and compounds for treating inflammatory bowel disease
PT98673B (pt) * 1990-08-15 1999-01-29 British Bio Technology Processo para a preparacao de compostos que sao antagonistas do factor de activacao de plaquetas por exemplo derivados de benzimidazole e de seus intermediarios

Also Published As

Publication number Publication date
ES2106682A1 (es) 1997-11-01

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