DE69611598T2 - Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen - Google Patents

Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen

Info

Publication number
DE69611598T2
DE69611598T2 DE69611598T DE69611598T DE69611598T2 DE 69611598 T2 DE69611598 T2 DE 69611598T2 DE 69611598 T DE69611598 T DE 69611598T DE 69611598 T DE69611598 T DE 69611598T DE 69611598 T2 DE69611598 T2 DE 69611598T2
Authority
DE
Germany
Prior art keywords
azoderivates
inflammable
treatment
aminosalicylic acid
colon diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69611598T
Other languages
English (en)
Other versions
DE69611598D1 (de
Inventor
Elena Carceller
Pere J Jimenez
Jordi Salas
Carmen Almansa
Javier Bartroli
Manel Merlos
Marta Giral
Dolors Balsa
Rosa Ferrando
Julian Garcia-Rafanell
Javier Forn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Palau Pharma SA
Original Assignee
J Uriach y Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES9501752A external-priority patent/ES2106682B1/es
Priority claimed from ES9501967A external-priority patent/ES2104513B1/es
Application filed by J Uriach y Cia SA filed Critical J Uriach y Cia SA
Application granted granted Critical
Publication of DE69611598D1 publication Critical patent/DE69611598D1/de
Publication of DE69611598T2 publication Critical patent/DE69611598T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69611598T 1995-09-08 1996-09-06 Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen Expired - Lifetime DE69611598T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES9501752A ES2106682B1 (es) 1995-09-08 1995-09-08 Nuevos derivados azo del acido 5-aminosalicilico.
ES9501967A ES2104513B1 (es) 1995-10-11 1995-10-11 Nuevos derivados del acido 5-aminosalicilico.
PCT/EP1996/003921 WO1997009329A1 (en) 1995-09-08 1996-09-06 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease

Publications (2)

Publication Number Publication Date
DE69611598D1 DE69611598D1 (de) 2001-02-22
DE69611598T2 true DE69611598T2 (de) 2001-06-07

Family

ID=26154915

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69611598T Expired - Lifetime DE69611598T2 (de) 1995-09-08 1996-09-06 Azoderivate von 5-aminosalicylsäure zur behandlung von enzündlichen darmerkrankungen

Country Status (17)

Country Link
US (1) US5747477A (de)
EP (1) EP0790998B1 (de)
JP (1) JP4115522B2 (de)
KR (1) KR100481300B1 (de)
AR (1) AR004198A1 (de)
AT (1) ATE198751T1 (de)
AU (1) AU6987596A (de)
BR (1) BR9606628A (de)
CA (1) CA2204747C (de)
DE (1) DE69611598T2 (de)
DK (1) DK0790998T3 (de)
ES (1) ES2155621T3 (de)
GR (1) GR3035622T3 (de)
MX (1) MX9702919A (de)
NO (1) NO308850B1 (de)
PT (1) PT790998E (de)
WO (1) WO1997009329A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6958324B2 (en) * 1998-12-02 2005-10-25 Inotek Pharmaceuticals Corporation Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease
ES2165803B1 (es) 2000-04-10 2003-09-16 Uriach & Cia Sa J Nueva sal de un derivado azo del acido 5-aminosalicilico
WO2001098268A2 (en) 2000-06-21 2001-12-27 Bristol-Myers Squibb Pharma Company Piperidine amides as modulators of chemokine receptor activity
JP4163946B2 (ja) * 2000-08-29 2008-10-08 バイオコン・リミテッド 免疫調節性化合物およびその誘導体並びにそれを用いて疾患を治療する方法
US8048924B2 (en) * 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
US20030119792A1 (en) * 2001-09-28 2003-06-26 Roca Manuel Merlos Method of inhibiting the production and/or effects of intestinal pro-inflammatory cytokines, prostaglandins and others
ES2565848T3 (es) 2004-07-07 2016-04-07 Biocon Limited Síntesis de compuestos inmunorreguladores unidos por grupos azoicos
WO2006125293A1 (en) * 2005-05-27 2006-11-30 Antibe Therapeutics Inc. Derivatives of 4- or 5-aminosalicylic acid
US7498355B2 (en) 2005-05-27 2009-03-03 Antibe Therapeutics Inc. Derivatives of 4- or 5-aminosalicylic acid
US7741359B2 (en) 2005-05-27 2010-06-22 Antibe Therapeutics Inc. Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs
CA2653869A1 (en) 2006-06-06 2007-12-13 Antibe Therapeutics Inc. Salts of trimebutine and n-desmethyl trimebutine
US7645801B2 (en) * 2007-01-29 2010-01-12 Alaven Pharmaceutical Llc Reduced irritant enema for treatment of inflammatory bowel disease (IBD)
CN105566153B (zh) * 2014-10-14 2019-05-31 中国医学科学院药物研究所 偶氮苯衍生物及其制法和药物组合物与用途
EP3837993A4 (de) 2018-06-19 2022-04-20 Coenbio Co., Ltd. Zusammensetzung zur verbesserung der darmfunktion mit leuconostoc-sp.-stamm
KR102173168B1 (ko) 2018-06-19 2020-11-03 주식회사 엠디헬스케어 류코노스톡속 균주를 포함하는 장 기능 개선용 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2396145A (en) * 1940-12-14 1946-03-05 Pharmscia Ab Heterocyclic sulphonamido azo compounds
US4312806A (en) * 1981-03-02 1982-01-26 G. D. Searle & Co. Method and compounds for treating inflammatory bowel disease
PT98673B (pt) * 1990-08-15 1999-01-29 British Bio Technology Processo para a preparacao de compostos que sao antagonistas do factor de activacao de plaquetas por exemplo derivados de benzimidazole e de seus intermediarios
GB9202791D0 (en) * 1992-02-11 1992-03-25 British Bio Technology Compounds
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.

Also Published As

Publication number Publication date
KR100481300B1 (ko) 2005-07-29
US5747477A (en) 1998-05-05
AR004198A1 (es) 1998-11-04
WO1997009329A1 (en) 1997-03-13
CA2204747A1 (en) 1997-03-13
MX9702919A (es) 1998-04-30
NO972113D0 (no) 1997-05-07
ES2155621T3 (es) 2001-05-16
NO308850B1 (no) 2000-11-06
CA2204747C (en) 2009-05-05
KR970707125A (ko) 1997-12-01
DE69611598D1 (de) 2001-02-22
ATE198751T1 (de) 2001-02-15
GR3035622T3 (en) 2001-06-29
JPH11501939A (ja) 1999-02-16
EP0790998B1 (de) 2001-01-17
EP0790998A1 (de) 1997-08-27
AU6987596A (en) 1997-03-27
DK0790998T3 (da) 2001-02-05
JP4115522B2 (ja) 2008-07-09
NO972113L (no) 1997-05-07
BR9606628A (pt) 1997-09-30
PT790998E (pt) 2001-04-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: PALAU PHARMA,S.A., PALAU-SOLITA I PLEGAMANS, B, ES

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC