ATE201992T1 - Carbostyrilderivat zur behandlung von ophthalmologischen erkrankungen - Google Patents
Carbostyrilderivat zur behandlung von ophthalmologischen erkrankungenInfo
- Publication number
- ATE201992T1 ATE201992T1 AT96932058T AT96932058T ATE201992T1 AT E201992 T1 ATE201992 T1 AT E201992T1 AT 96932058 T AT96932058 T AT 96932058T AT 96932058 T AT96932058 T AT 96932058T AT E201992 T1 ATE201992 T1 AT E201992T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- carbostyril derivative
- ophthalmological diseases
- ophthalmological
- diseases
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26389695 | 1995-10-12 | ||
| JP5733796 | 1996-03-14 | ||
| PCT/JP1996/002850 WO1997013515A1 (en) | 1995-10-12 | 1996-10-01 | Carbostyril derivative for curing ophthalmological diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE201992T1 true ATE201992T1 (de) | 2001-06-15 |
Family
ID=26398366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96932058T ATE201992T1 (de) | 1995-10-12 | 1996-10-01 | Carbostyrilderivat zur behandlung von ophthalmologischen erkrankungen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6060486A (de) |
| EP (1) | EP0859615B1 (de) |
| KR (1) | KR100281865B1 (de) |
| CN (1) | CN1132580C (de) |
| AR (3) | AR004214A1 (de) |
| AT (1) | ATE201992T1 (de) |
| AU (1) | AU709734B2 (de) |
| CA (1) | CA2234247C (de) |
| DE (1) | DE69613386T2 (de) |
| DK (1) | DK0859615T3 (de) |
| ES (1) | ES2159043T3 (de) |
| GR (1) | GR3036457T3 (de) |
| MX (1) | MX9802817A (de) |
| PT (1) | PT859615E (de) |
| TW (1) | TW446702B (de) |
| WO (1) | WO1997013515A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3093661B2 (ja) | 1995-10-12 | 2000-10-03 | 大塚製薬株式会社 | 眼疾患治療剤 |
| US6506412B2 (en) | 2000-11-29 | 2003-01-14 | Sciencebased Health | Treatment of dry eye syndrome |
| US6623754B2 (en) * | 2001-05-21 | 2003-09-23 | Noveon Ip Holdings Corp. | Dosage form of N-acetyl cysteine |
| DE10133870A1 (de) * | 2001-07-12 | 2003-02-06 | Chris P Lohmann | Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge |
| KR100907407B1 (ko) * | 2002-09-28 | 2009-07-10 | 주식회사 케이티 | 대량 메시지 동보 전송을 위한 메시지 예약 및 전송 방법 |
| KR100681360B1 (ko) * | 2003-07-30 | 2007-02-12 | 오츠카 세이야쿠 가부시키가이샤 | 타액분비 촉진용 카르보스티릴 유도체 |
| JP4674162B2 (ja) * | 2003-11-14 | 2011-04-20 | 千寿製薬株式会社 | アミノグリコシド系抗生物質およびブロムフェナクを含有する水溶液製剤 |
| TWI340650B (en) | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| KR20070061537A (ko) | 2004-08-27 | 2007-06-13 | 센주 세이야꾸 가부시키가이샤 | 건성안 치료용 안약액 |
| TWI363626B (en) * | 2004-11-15 | 2012-05-11 | Otsuka Pharma Co Ltd | Aqueous ophthalmic suspension of crystalline rebamipide |
| TW200808375A (en) * | 2006-05-12 | 2008-02-16 | Otsuka Pharma Co Ltd | Hydrogel suspension and manufacturing process thereof |
| TWI415629B (zh) * | 2006-10-26 | 2013-11-21 | Otsuka Pharma Co Ltd | 含有瑞巴匹特之水性醫藥懸浮物及其製造方法 |
| RU2331408C1 (ru) * | 2007-05-31 | 2008-08-20 | Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО БГМУ РОСЗДРАВА) | Глазная мазь |
| AU2009261101B2 (en) * | 2008-06-19 | 2013-11-07 | Otsuka Pharmaceutical Co., Ltd. | A pharmaceutical composition comprising rebamipide |
| WO2012114317A1 (en) | 2011-02-25 | 2012-08-30 | Nuformix Limited | Novel rebamipide complexes and cocrystals |
| TW201322982A (zh) | 2011-11-01 | 2013-06-16 | Otsuka Pharma Co Ltd | 用於治療前眼疾病之藥劑，該藥劑包含瑞巴派特及眼淚保持劑 |
| KR101692578B1 (ko) * | 2013-04-18 | 2017-01-03 | 삼진제약주식회사 | 레바미피드 또는 이의 전구체를 포함하는 안구건조증의 예방 또는 치료를 위한 경구용 약제학적 조성물 |
| US10004395B2 (en) | 2014-05-02 | 2018-06-26 | Massachusetts Eye And Ear Infirmary | Grading corneal fluorescein staining |
| KR20170039347A (ko) | 2015-10-01 | 2017-04-11 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
| KR102307958B1 (ko) | 2015-10-01 | 2021-10-05 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
| ES3036888T3 (en) * | 2017-03-05 | 2025-09-25 | Resdevco Res And Development Co Ltd | Eye drops for treatment of irritation or damage due to sjögren's syndrome |
| KR102615076B1 (ko) | 2021-07-14 | 2023-12-19 | 대우제약 주식회사 | 안정한 레바미피드 점안제의 대용량 제조 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI80022C (fi) * | 1982-07-05 | 1990-04-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat. |
| JPH0713138B2 (ja) * | 1986-07-30 | 1995-02-15 | 保土谷化学工業株式会社 | ポリテトラメチレンエ−テルグリコ−ルの製法 |
| DE69207560T2 (de) * | 1991-06-07 | 1996-06-27 | Otsuka Pharma Co Ltd | Antidiabetikum |
| TW227558B (de) * | 1992-05-14 | 1994-08-01 | Otsuka Pharma Co Ltd | |
| CA2136108A1 (en) * | 1993-03-18 | 1994-09-29 | Makoto Sakamoto | Carbostyril derivatives as matrix metalloproteinases inhibitors |
| ATE184793T1 (de) * | 1993-10-21 | 1999-10-15 | Otsuka Pharma Co Ltd | Die verwendung von carbostyrilderivaten zur herstellung eines arzneimittels zur hemmung der produktion von interleukin-8 |
| KR970704439A (ko) * | 1994-08-10 | 1997-09-06 | 오쓰카 아키히코 | 눈의 염증 및/또는 상처의 예방 및 치료 방법(Method of preventing and treating ophthalmic inflammation and/or wound) |
-
1996
- 1996-09-10 AR ARP960104658A patent/AR004214A1/es not_active Application Discontinuation
- 1996-10-01 CA CA002234247A patent/CA2234247C/en not_active Expired - Lifetime
- 1996-10-01 KR KR1019980702671A patent/KR100281865B1/ko not_active Expired - Lifetime
- 1996-10-01 ES ES96932058T patent/ES2159043T3/es not_active Expired - Lifetime
- 1996-10-01 US US09/051,194 patent/US6060486A/en not_active Expired - Lifetime
- 1996-10-01 DK DK96932058T patent/DK0859615T3/da active
- 1996-10-01 AT AT96932058T patent/ATE201992T1/de active
- 1996-10-01 EP EP96932058A patent/EP0859615B1/de not_active Expired - Lifetime
- 1996-10-01 DE DE69613386T patent/DE69613386T2/de not_active Expired - Lifetime
- 1996-10-01 CN CN96198194A patent/CN1132580C/zh not_active Expired - Lifetime
- 1996-10-01 WO PCT/JP1996/002850 patent/WO1997013515A1/en not_active Ceased
- 1996-10-01 PT PT96932058T patent/PT859615E/pt unknown
- 1996-10-01 AU AU70975/96A patent/AU709734B2/en not_active Expired
- 1996-10-02 TW TW085112022A patent/TW446702B/zh not_active IP Right Cessation
-
1998
- 1998-04-08 MX MX9802817A patent/MX9802817A/es unknown
-
2001
- 2001-08-27 GR GR20010401307T patent/GR3036457T3/el unknown
-
2006
- 2006-08-25 AR ARP060103704A patent/AR055393A2/es not_active Application Discontinuation
-
2008
- 2008-12-29 AR ARP080105747A patent/AR070051A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR004214A1 (es) | 1998-11-04 |
| KR100281865B1 (ko) | 2001-02-15 |
| US6060486A (en) | 2000-05-09 |
| TW446702B (en) | 2001-07-21 |
| ES2159043T3 (es) | 2001-09-16 |
| CA2234247A1 (en) | 1997-04-17 |
| CN1132580C (zh) | 2003-12-31 |
| DE69613386T2 (de) | 2002-05-23 |
| WO1997013515A1 (en) | 1997-04-17 |
| DE69613386D1 (de) | 2001-07-19 |
| AU709734B2 (en) | 1999-09-02 |
| DK0859615T3 (da) | 2001-09-03 |
| PT859615E (pt) | 2001-09-28 |
| KR19990064187A (ko) | 1999-07-26 |
| MX9802817A (es) | 1998-09-30 |
| AU7097596A (en) | 1997-04-30 |
| AR055393A2 (es) | 2007-08-22 |
| CA2234247C (en) | 2005-05-10 |
| EP0859615B1 (de) | 2001-06-13 |
| CN1202108A (zh) | 1998-12-16 |
| GR3036457T3 (en) | 2001-11-30 |
| EP0859615A1 (de) | 1998-08-26 |
| AR070051A2 (es) | 2010-03-10 |
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