MX9702919A - Derivados azo del acido 5-aminosalicilico para el tratameitno de la enfermedad inflamatoria intestinal. - Google Patents

Derivados azo del acido 5-aminosalicilico para el tratameitno de la enfermedad inflamatoria intestinal.

Info

Publication number
MX9702919A
MX9702919A MX9702919A MX9702919A MX9702919A MX 9702919 A MX9702919 A MX 9702919A MX 9702919 A MX9702919 A MX 9702919A MX 9702919 A MX9702919 A MX 9702919A MX 9702919 A MX9702919 A MX 9702919A
Authority
MX
Mexico
Prior art keywords
treatment
inflammatory bowel
bowel disease
aminosalicylic acid
azo derivatives
Prior art date
Application number
MX9702919A
Other languages
English (en)
Other versions
MXPA97002919A (es
Inventor
Elena Carceller
Pere J Jimenez
Jordi Salas
Carmen Almansa
Javier Bartroli
Manuel Merlos
Marta Giral
Dolors Balsa
Rosa Ferrando
Original Assignee
Uriach & Cia Sa J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES9501752A external-priority patent/ES2106682B1/es
Priority claimed from ES9501967A external-priority patent/ES2104513B1/es
Application filed by Uriach & Cia Sa J filed Critical Uriach & Cia Sa J
Publication of MXPA97002919A publication Critical patent/MXPA97002919A/es
Publication of MX9702919A publication Critical patent/MX9702919A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

(Ver Formula). Los compuestos de formula general 1 y sus sales y solvatos son utiles en el tratamiento de o prevencion de la enfermedad inflamatoria intestinal. Se describen también composiciones farmacéuticas que incluyen estos compuestos y procedimientos para su preparacion.
MX9702919A 1995-09-08 1996-09-06 Derivados azo del acido 5-aminosalicilico para el tratameitno de la enfermedad inflamatoria intestinal. MX9702919A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
ES9501752A ES2106682B1 (es) 1995-09-08 1995-09-08 Nuevos derivados azo del acido 5-aminosalicilico.
ESES9501752 1995-09-08
ESES9501967 1995-10-11
ES9501967A ES2104513B1 (es) 1995-10-11 1995-10-11 Nuevos derivados del acido 5-aminosalicilico.
PCT/EP1996/003921 WO1997009329A1 (en) 1995-09-08 1996-09-06 Azo derivatives of 5-aminosalicylic acid for treatment of inflammatory bowel disease

Publications (2)

Publication Number Publication Date
MXPA97002919A MXPA97002919A (es) 1998-04-01
MX9702919A true MX9702919A (es) 1998-04-30

Family

ID=26154915

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9702919A MX9702919A (es) 1995-09-08 1996-09-06 Derivados azo del acido 5-aminosalicilico para el tratameitno de la enfermedad inflamatoria intestinal.

Country Status (17)

Country Link
US (1) US5747477A (es)
EP (1) EP0790998B1 (es)
JP (1) JP4115522B2 (es)
KR (1) KR100481300B1 (es)
AR (1) AR004198A1 (es)
AT (1) ATE198751T1 (es)
AU (1) AU6987596A (es)
BR (1) BR9606628A (es)
CA (1) CA2204747C (es)
DE (1) DE69611598T2 (es)
DK (1) DK0790998T3 (es)
ES (1) ES2155621T3 (es)
GR (1) GR3035622T3 (es)
MX (1) MX9702919A (es)
NO (1) NO308850B1 (es)
PT (1) PT790998E (es)
WO (1) WO1997009329A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6958324B2 (en) * 1998-12-02 2005-10-25 Inotek Pharmaceuticals Corporation Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease
ES2165803B1 (es) * 2000-04-10 2003-09-16 Uriach & Cia Sa J Nueva sal de un derivado azo del acido 5-aminosalicilico
CA2413418A1 (en) 2000-06-21 2001-12-27 Joseph B. Santella Piperidine amides as modulators of chemokine receptor activity
DE60140491D1 (de) 2000-08-29 2009-12-24 Biocon Ltd Verwendung einer pharmazeutischen Zusammensetzung mit einem Para-Aminophenylessigsäurederivat für die Behandlung von entzündlichen Erkrankungen des Magen-Darmtrakts
US8048924B2 (en) * 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
US20030119792A1 (en) * 2001-09-28 2003-06-26 Roca Manuel Merlos Method of inhibiting the production and/or effects of intestinal pro-inflammatory cytokines, prostaglandins and others
DK1773767T3 (en) 2004-07-07 2016-03-21 Biocon Ltd Synthesis of azo bound in immune regulatory relations
US7741359B2 (en) 2005-05-27 2010-06-22 Antibe Therapeutics Inc. Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs
WO2006125293A1 (en) 2005-05-27 2006-11-30 Antibe Therapeutics Inc. Derivatives of 4- or 5-aminosalicylic acid
US7498355B2 (en) 2005-05-27 2009-03-03 Antibe Therapeutics Inc. Derivatives of 4- or 5-aminosalicylic acid
US20110144188A1 (en) 2006-06-06 2011-06-16 Antibe Therapeutics Inc. Salts of trimebutine and n-desmethyl trimebutine
US7645801B2 (en) 2007-01-29 2010-01-12 Alaven Pharmaceutical Llc Reduced irritant enema for treatment of inflammatory bowel disease (IBD)
CN105566153B (zh) * 2014-10-14 2019-05-31 中国医学科学院药物研究所 偶氮苯衍生物及其制法和药物组合物与用途
KR102173168B1 (ko) 2018-06-19 2020-11-03 주식회사 엠디헬스케어 류코노스톡속 균주를 포함하는 장 기능 개선용 조성물
WO2019245225A1 (ko) 2018-06-19 2019-12-26 (주)코엔바이오 류코노스톡속 균주를 포함하는 장 기능 개선용 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2396145A (en) * 1940-12-14 1946-03-05 Pharmscia Ab Heterocyclic sulphonamido azo compounds
US4312806A (en) * 1981-03-02 1982-01-26 G. D. Searle & Co. Method and compounds for treating inflammatory bowel disease
PT98673B (pt) * 1990-08-15 1999-01-29 British Bio Technology Processo para a preparacao de compostos que sao antagonistas do factor de activacao de plaquetas por exemplo derivados de benzimidazole e de seus intermediarios
GB9202791D0 (en) * 1992-02-11 1992-03-25 British Bio Technology Compounds
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.

Also Published As

Publication number Publication date
NO972113L (no) 1997-05-07
CA2204747A1 (en) 1997-03-13
GR3035622T3 (en) 2001-06-29
JP4115522B2 (ja) 2008-07-09
NO972113D0 (no) 1997-05-07
ATE198751T1 (de) 2001-02-15
US5747477A (en) 1998-05-05
CA2204747C (en) 2009-05-05
PT790998E (pt) 2001-04-30
ES2155621T3 (es) 2001-05-16
JPH11501939A (ja) 1999-02-16
AU6987596A (en) 1997-03-27
EP0790998A1 (en) 1997-08-27
KR970707125A (ko) 1997-12-01
BR9606628A (pt) 1997-09-30
DE69611598D1 (de) 2001-02-22
KR100481300B1 (ko) 2005-07-29
WO1997009329A1 (en) 1997-03-13
DK0790998T3 (da) 2001-02-05
EP0790998B1 (en) 2001-01-17
AR004198A1 (es) 1998-11-04
DE69611598T2 (de) 2001-06-07
NO308850B1 (no) 2000-11-06

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