ATE227130T1 - 5-alpha-pregnan-3-beta-ol-20-one 3-sulfate für di behandlung von tumoren und zns krankheiten - Google Patents
5-alpha-pregnan-3-beta-ol-20-one 3-sulfate für di behandlung von tumoren und zns krankheitenInfo
- Publication number
- ATE227130T1 ATE227130T1 AT98918789T AT98918789T ATE227130T1 AT E227130 T1 ATE227130 T1 AT E227130T1 AT 98918789 T AT98918789 T AT 98918789T AT 98918789 T AT98918789 T AT 98918789T AT E227130 T1 ATE227130 T1 AT E227130T1
- Authority
- AT
- Austria
- Prior art keywords
- pregnan
- tumors
- beta
- alpha
- sulfate
- Prior art date
Links
- AURFZBICLPNKBZ-FZCSVUEKSA-N 3beta-hydroxy-5alpha-pregnan-20-one Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)C)[C@@]2(C)CC1 AURFZBICLPNKBZ-FZCSVUEKSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- AURFZBICLPNKBZ-UHFFFAOYSA-N Pregnanolone Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(=O)C)C1(C)CC2 AURFZBICLPNKBZ-UHFFFAOYSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85056797A | 1997-05-02 | 1997-05-02 | |
| PCT/US1998/008456 WO1998050042A1 (en) | 1997-05-02 | 1998-04-28 | Pregnan-3-ol-20-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE227130T1 true ATE227130T1 (de) | 2002-11-15 |
Family
ID=25308504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98918789T ATE227130T1 (de) | 1997-05-02 | 1998-04-28 | 5-alpha-pregnan-3-beta-ol-20-one 3-sulfate für di behandlung von tumoren und zns krankheiten |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0981349B1 (de) |
| JP (1) | JP2001525807A (de) |
| KR (1) | KR20010012157A (de) |
| CN (1) | CN1254283A (de) |
| AR (1) | AR012638A1 (de) |
| AT (1) | ATE227130T1 (de) |
| AU (1) | AU739146B2 (de) |
| BR (1) | BR9809376A (de) |
| CA (1) | CA2289006A1 (de) |
| DE (1) | DE69809223T2 (de) |
| DK (1) | DK0981349T3 (de) |
| ES (1) | ES2186153T3 (de) |
| PT (1) | PT981349E (de) |
| WO (1) | WO1998050042A1 (de) |
| ZA (1) | ZA983705B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2321728C (en) | 1998-03-11 | 2008-12-09 | Torbjorn Backstrom | Epiallopregnanolone in the treatment of cns disorders |
| SE0104423D0 (sv) * | 2001-12-27 | 2001-12-27 | Umecrine Ab | Pregnane steroids and their use in the treatment of CNS disorders |
| US7572780B2 (en) | 2003-01-21 | 2009-08-11 | Dimera, Incorporated | Method and kit for reducing the symptoms of peripheral vascular disease |
| PT2030622E (pt) | 2005-03-24 | 2011-06-02 | Univ Emory | Indicação da dose de progesterona no tratamento de um traumatismo crânio-encefálico |
| US7473687B2 (en) | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
| WO2006117592A1 (en) * | 2005-04-29 | 2006-11-09 | Inserm | Methods of modulating nuclear receptors |
| ES2566765T3 (es) | 2010-01-14 | 2016-04-15 | Asarina Pharma Ab | Una composición farmacéutica que contiene 3-beta-hidroxi-5-alfa-pregnan-20-ona con propiedades de almacenamiento y solubilidad mejoradas |
-
1998
- 1998-04-28 DK DK98918789T patent/DK0981349T3/da active
- 1998-04-28 AU AU71647/98A patent/AU739146B2/en not_active Ceased
- 1998-04-28 DE DE69809223T patent/DE69809223T2/de not_active Expired - Fee Related
- 1998-04-28 BR BR9809376-2A patent/BR9809376A/pt not_active IP Right Cessation
- 1998-04-28 JP JP54815598A patent/JP2001525807A/ja active Pending
- 1998-04-28 CA CA002289006A patent/CA2289006A1/en not_active Abandoned
- 1998-04-28 AT AT98918789T patent/ATE227130T1/de not_active IP Right Cessation
- 1998-04-28 ES ES98918789T patent/ES2186153T3/es not_active Expired - Lifetime
- 1998-04-28 WO PCT/US1998/008456 patent/WO1998050042A1/en not_active Ceased
- 1998-04-28 EP EP98918789A patent/EP0981349B1/de not_active Expired - Lifetime
- 1998-04-28 KR KR19997010102A patent/KR20010012157A/ko not_active Withdrawn
- 1998-04-28 PT PT98918789T patent/PT981349E/pt unknown
- 1998-04-28 CN CN98804719A patent/CN1254283A/zh active Pending
- 1998-04-30 AR ARP980102025A patent/AR012638A1/es unknown
- 1998-04-30 ZA ZA9803705A patent/ZA983705B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001525807A (ja) | 2001-12-11 |
| AU739146B2 (en) | 2001-10-04 |
| EP0981349A1 (de) | 2000-03-01 |
| BR9809376A (pt) | 2000-07-04 |
| ZA983705B (en) | 1999-11-01 |
| CN1254283A (zh) | 2000-05-24 |
| DK0981349T3 (da) | 2003-03-10 |
| PT981349E (pt) | 2003-01-31 |
| DE69809223D1 (de) | 2002-12-12 |
| KR20010012157A (ko) | 2001-02-15 |
| AR012638A1 (es) | 2000-11-08 |
| CA2289006A1 (en) | 1998-11-12 |
| ES2186153T3 (es) | 2003-05-01 |
| EP0981349B1 (de) | 2002-11-06 |
| AU7164798A (en) | 1998-11-27 |
| DE69809223T2 (de) | 2003-07-24 |
| WO1998050042A1 (en) | 1998-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0981349 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |