DE69809223D1 - 5-alpha-pregnan-3-beta-ol-20-one 3-sulfate für di behandlung von tumoren und zns krankheiten - Google Patents

5-alpha-pregnan-3-beta-ol-20-one 3-sulfate für di behandlung von tumoren und zns krankheiten

Info

Publication number
DE69809223D1
DE69809223D1 DE69809223T DE69809223T DE69809223D1 DE 69809223 D1 DE69809223 D1 DE 69809223D1 DE 69809223 T DE69809223 T DE 69809223T DE 69809223 T DE69809223 T DE 69809223T DE 69809223 D1 DE69809223 D1 DE 69809223D1
Authority
DE
Germany
Prior art keywords
pregnan
tumors
beta
alpha
sulfate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69809223T
Other languages
English (en)
Other versions
DE69809223T2 (de
Inventor
Z Kagan
Muzafar Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Application granted granted Critical
Publication of DE69809223D1 publication Critical patent/DE69809223D1/de
Publication of DE69809223T2 publication Critical patent/DE69809223T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE69809223T 1997-05-02 1998-04-28 5-alpha-pregnan-3-beta-ol-20-one 3-sulfate für di behandlung von tumoren und zns krankheiten Expired - Fee Related DE69809223T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85056797A 1997-05-02 1997-05-02
PCT/US1998/008456 WO1998050042A1 (en) 1997-05-02 1998-04-28 Pregnan-3-ol-20-ones

Publications (2)

Publication Number Publication Date
DE69809223D1 true DE69809223D1 (de) 2002-12-12
DE69809223T2 DE69809223T2 (de) 2003-07-24

Family

ID=25308504

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69809223T Expired - Fee Related DE69809223T2 (de) 1997-05-02 1998-04-28 5-alpha-pregnan-3-beta-ol-20-one 3-sulfate für di behandlung von tumoren und zns krankheiten

Country Status (15)

Country Link
EP (1) EP0981349B1 (de)
JP (1) JP2001525807A (de)
KR (1) KR20010012157A (de)
CN (1) CN1254283A (de)
AR (1) AR012638A1 (de)
AT (1) ATE227130T1 (de)
AU (1) AU739146B2 (de)
BR (1) BR9809376A (de)
CA (1) CA2289006A1 (de)
DE (1) DE69809223T2 (de)
DK (1) DK0981349T3 (de)
ES (1) ES2186153T3 (de)
PT (1) PT981349E (de)
WO (1) WO1998050042A1 (de)
ZA (1) ZA983705B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999045931A1 (en) * 1998-03-11 1999-09-16 Baeckstroem Torbjoern Epiallopregnanolone in the treatment of cns disorders
SE0104423D0 (sv) * 2001-12-27 2001-12-27 Umecrine Ab Pregnane steroids and their use in the treatment of CNS disorders
US7572780B2 (en) 2003-01-21 2009-08-11 Dimera, Incorporated Method and kit for reducing the symptoms of peripheral vascular disease
DK1868614T3 (da) 2005-03-24 2012-11-12 Univ Emory Dosisregime til behandling af en traumatisk hjerneskade med progesteron
US7473687B2 (en) 2005-03-24 2009-01-06 Emory University Methods for the treatment of a traumatic central nervous system injury
WO2006117592A1 (en) * 2005-04-29 2006-11-09 Inserm Methods of modulating nuclear receptors
CN102753181B (zh) 2010-01-14 2014-09-17 优麦克里尼穆德公司 具有改进的储存特性和溶解度特性的包含3-β-羟基-5-α-孕烷-20-酮的药物组合物

Also Published As

Publication number Publication date
DE69809223T2 (de) 2003-07-24
WO1998050042A1 (en) 1998-11-12
CN1254283A (zh) 2000-05-24
ES2186153T3 (es) 2003-05-01
KR20010012157A (ko) 2001-02-15
ATE227130T1 (de) 2002-11-15
CA2289006A1 (en) 1998-11-12
ZA983705B (en) 1999-11-01
EP0981349A1 (de) 2000-03-01
EP0981349B1 (de) 2002-11-06
DK0981349T3 (da) 2003-03-10
JP2001525807A (ja) 2001-12-11
BR9809376A (pt) 2000-07-04
AR012638A1 (es) 2000-11-08
PT981349E (pt) 2003-01-31
AU7164798A (en) 1998-11-27
AU739146B2 (en) 2001-10-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee