ES8100263A1 - Procedimiento para preparar un derivado de acido 1-bencil-1,2,5,6-tetrahidropiridina-3-carboxilico - Google Patents

Procedimiento para preparar un derivado de acido 1-bencil-1,2,5,6-tetrahidropiridina-3-carboxilico

Info

Publication number
ES8100263A1
ES8100263A1 ES486051A ES486051A ES8100263A1 ES 8100263 A1 ES8100263 A1 ES 8100263A1 ES 486051 A ES486051 A ES 486051A ES 486051 A ES486051 A ES 486051A ES 8100263 A1 ES8100263 A1 ES 8100263A1
Authority
ES
Spain
Prior art keywords
amino
alkyl
manufacture
tetrahydropyridine
halogeno
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486051A
Other languages
English (en)
Other versions
ES486051A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES8100263A1 publication Critical patent/ES8100263A1/es
Publication of ES486051A0 publication Critical patent/ES486051A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE UN DERIVADO DEL ACIDO 1-BENCIL-1, 2, 5, 6-TETRAHIDROPIRINA-3-CARBOXILICO. CONSTA DE LAS SIGUIENTES OPERACIONES: 1. REACCION DE UN COMPUESTO DE FORMULA GENERAL (I) CON UN HALURO DE BENCILO DE FORMULA GENERAL (II). 2. REACCION DE UN COMPUESTO DE FORMULA (II) CON UN ALDEHIDO DE FORMULA GENERAL (III) EN PRESENCIA DE UN AGENTE REDUCTOR. 3. HIDROLISIS DE UN COMPUESTO (IV) CUANDO R ELEVADO A 1 ES UN RADICAL HIDROXI, O 4. HIDROLISIS DE UN COMPUESTO DE FORMULA GENERAL V CUANDO R ELEVADO A 1 ES UN RADICAL HIDROXI O AMINO Y EL ANILLO DE BENCENO A LLEVA UN RADICAL CARAMIDO. TRATAMIENTO DE TROMBOSIS O ENFERMEDADES VASCULARES OCLUSIVAS. *FORMULA*
ES486051A 1978-11-17 1979-11-16 Procedimiento para preparar un derivado de acido 1-bencil-1,2,5,6-tetrahidropiridina-3-carboxilico Granted ES486051A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7844987 1978-11-17
GB7932817 1979-09-21

Publications (2)

Publication Number Publication Date
ES8100263A1 true ES8100263A1 (es) 1980-11-01
ES486051A0 ES486051A0 (es) 1980-11-01

Family

ID=26269625

Family Applications (1)

Application Number Title Priority Date Filing Date
ES486051A Granted ES486051A0 (es) 1978-11-17 1979-11-16 Procedimiento para preparar un derivado de acido 1-bencil-1,2,5,6-tetrahidropiridina-3-carboxilico

Country Status (5)

Country Link
US (1) US4238488A (es)
EP (1) EP0011447B1 (es)
AU (1) AU525091B2 (es)
DE (1) DE2964451D1 (es)
ES (1) ES486051A0 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083378A1 (en) * 1981-12-22 1983-07-13 Chugai Seiyaku Kabushiki Kaisha Tetrahydronicotinamide derivatives, a process for producing the same and a pharmaceutical composition comprising the same
DE3685382D1 (de) * 1985-08-27 1992-06-25 Ciba Geigy Ag Hydropyridin-derivate.
US4745123A (en) * 1986-02-18 1988-05-17 Warner-Lambert Company Substituted tetrahydro-3-pyridine-carboxylic acid, ester, and amide cholinergic agents
US4957928A (en) * 1986-06-26 1990-09-18 Ciba-Geigy Corporation Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
US6410746B1 (en) * 1999-04-27 2002-06-25 Research Foundation Of State University Of New York, The Metal cataltsts and methods for making and using same
WO2003018184A2 (en) 2001-08-27 2003-03-06 The Research Foundation Of State University Of New York Solid support dirhodium catalyst compositions and methods for making and using same
AU2002331753A1 (en) 2001-08-27 2003-03-10 The Research Foundation Of State University Of New York Dirhodium catalyst compositions and methods for using same
US7700798B1 (en) 2005-06-08 2010-04-20 The Research Foundation Of State University Of New York Erogorgiaene congeners and methods and intermediates useful in the preparation of same
US7816536B2 (en) * 2005-06-10 2010-10-19 The Research Foundation Of State University Of New York 4-substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles and methods for making same
US7385064B1 (en) 2005-11-30 2008-06-10 The Research Foundation Of State University Of New York Catalysts for use in enantioselective synthesis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2221770A1 (de) 1972-05-04 1973-11-15 Bayer Ag Verfahren zur herstellung von tetrahydropyridinen

Also Published As

Publication number Publication date
EP0011447A1 (en) 1980-05-28
US4238488A (en) 1980-12-09
EP0011447B1 (en) 1983-01-05
DE2964451D1 (en) 1983-02-10
AU5283579A (en) 1980-05-22
ES486051A0 (es) 1980-11-01
AU525091B2 (en) 1982-10-21

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