ES8401078A1 - Procedimiento para la obtencion de esteres del acido 7b-2-(2-amino-4-tiazolil)-2-sin)-metoxiiminoacetamido-3-cefem-4-carboxilico. - Google Patents
Procedimiento para la obtencion de esteres del acido 7b-2-(2-amino-4-tiazolil)-2-sin)-metoxiiminoacetamido-3-cefem-4-carboxilico.Info
- Publication number
- ES8401078A1 ES8401078A1 ES516591A ES516591A ES8401078A1 ES 8401078 A1 ES8401078 A1 ES 8401078A1 ES 516591 A ES516591 A ES 516591A ES 516591 A ES516591 A ES 516591A ES 8401078 A1 ES8401078 A1 ES 8401078A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- esters
- cephalosporin esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ESTERES DEL ACIDO 7B-1-(2-AMINO-4-TIAZOLIL)-2-(SIN)-METOXIIMINOAC ETAMIDO-3-CEFEM-4-CARBOXILICO Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE R1 ES HIDROGENO O ALQUILO INFERIOR; R2 ES ALQUILO INFERIOR; Y AM ES AMINO.CONSISTE EN LA REACCION DE DISOCIACION DE UN COMPUESTO DE FORMULA (II), EN LA QUE RO ES HIDROXI, HIDROXI ESTERIFICADO O AMINO Y R1, R2 Y AM TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), TRANSFORMANDO EL GRUPO RO EN HRO. LA DISOCIACION SE EFECTUA POR TRATAMIENTO CON UN ACIDO EN UN DISOLVENTE INERTE.ESTOS COMPUESTOSTIENEN APLICACIONES FARMACOLOGICAS COMO ANTIBIOTICOS ANTIBACTERIALES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH919680 | 1980-12-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8401078A1 true ES8401078A1 (es) | 1983-11-16 |
ES516591A0 ES516591A0 (es) | 1983-11-16 |
Family
ID=4349398
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES507907A Granted ES507907A0 (es) | 1980-12-12 | 1981-12-11 | Procedimiento para la obtencion de esteres del acido 7b-(2-(2-animo-4-tiazolil)-2-(sin)-metoxiimino-acetamido)-3-cefem-4-caboxilico. |
ES516590A Granted ES516590A0 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7 2(2-amino-4-tiazolil)-2-(sin)-metoxiiminoacetamido)-3-cefem-4-carboxilico. |
ES516593A Granted ES516593A0 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7b-2-(2-amino-4-tiazolil)-2-(sin)-metoxiiminoacetamido)-3-cefem-4-carboxilico. |
ES516592A Expired ES8307820A1 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7b-2-(2amino-4-tiazolil)-2-(sin)-metoxiiminoacetamido-3-cefem-4-carboxilico. |
ES516594A Expired ES8401080A1 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7 -2-(2amino-4-tiazolil)-2-(sin)-metoxiimionoacetamido)-3-cefem-4-carboxilico. |
ES516591A Granted ES516591A0 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7b-2-(2-amino-4-tiazolil)-2-sin)-metoxiiminoacetamido-3-cefem-4-carboxilico. |
Family Applications Before (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES507907A Granted ES507907A0 (es) | 1980-12-12 | 1981-12-11 | Procedimiento para la obtencion de esteres del acido 7b-(2-(2-animo-4-tiazolil)-2-(sin)-metoxiimino-acetamido)-3-cefem-4-caboxilico. |
ES516590A Granted ES516590A0 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7 2(2-amino-4-tiazolil)-2-(sin)-metoxiiminoacetamido)-3-cefem-4-carboxilico. |
ES516593A Granted ES516593A0 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7b-2-(2-amino-4-tiazolil)-2-(sin)-metoxiiminoacetamido)-3-cefem-4-carboxilico. |
ES516592A Expired ES8307820A1 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7b-2-(2amino-4-tiazolil)-2-(sin)-metoxiiminoacetamido-3-cefem-4-carboxilico. |
ES516594A Expired ES8401080A1 (es) | 1980-12-12 | 1982-10-16 | Procedimiento para la obtencion de esteres del acido 7 -2-(2amino-4-tiazolil)-2-(sin)-metoxiimionoacetamido)-3-cefem-4-carboxilico. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0054512A3 (es) |
JP (1) | JPS57123190A (es) |
KR (1) | KR830007683A (es) |
AR (1) | AR231984A1 (es) |
AU (1) | AU7846681A (es) |
DD (1) | DD208155A5 (es) |
DK (1) | DK550081A (es) |
ES (6) | ES507907A0 (es) |
FI (1) | FI813946L (es) |
GB (1) | GB2111043B (es) |
GR (1) | GR76967B (es) |
HU (1) | HU185985B (es) |
IE (1) | IE52008B1 (es) |
IL (1) | IL64506A (es) |
NO (1) | NO814232L (es) |
NZ (1) | NZ199255A (es) |
PT (1) | PT74119B (es) |
ZA (1) | ZA818622B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK554481A (da) * | 1980-12-15 | 1982-06-16 | Fujisawa Pharmaceutical Co | Fremgangsmaade til fremstilling af cephalosporansyrederivater |
JPS57156495A (en) * | 1981-03-23 | 1982-09-27 | Kyoto Yakuhin Kogyo Kk | Cephalosporin derivative and remedy for microbism used in oral administration |
IT1190897B (it) * | 1982-06-29 | 1988-02-24 | Opos Biochimica Srl | Procedimento per la preparazione dell'estere 1-etossicarbonilossietilico dell'acido 6-(d(-)-alfa aminoalfa fenilacetamido)-penicillanico |
US4606865A (en) * | 1982-09-20 | 1986-08-19 | Astra Lakemedel Aktiebolag | Methods for the preparation of α-bromodiethylcarbonate |
JPS59116291A (ja) * | 1982-12-06 | 1984-07-05 | Fujisawa Pharmaceut Co Ltd | 7−置換−3−セフエム−4−カルボン酸エステルおよびその製法 |
US5202454A (en) * | 1986-07-11 | 1993-04-13 | Societe Nationale Des Poudres Et Explosifs | Process for the manufacture of 1-bromoalkyl hydrocarbyl carbonates |
KR0173796B1 (ko) * | 1989-10-28 | 1999-02-01 | 기까미 기즈히꼬 | 세팔로스포린 화합물 및 그의 제조방법 |
NZ333687A (en) * | 1996-07-26 | 2000-08-25 | Gilead Sciences Inc | Phosphonomethoxy nucleotide analogs |
US20040224916A1 (en) | 2003-01-14 | 2004-11-11 | Gilead Sciences, Inc. | Compositions and methods for combination antiviral therapy |
TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
TWI375560B (en) | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3965099A (en) * | 1974-06-26 | 1976-06-22 | Smithkline Corporation | Cephalosporin esters with antibacterial activity |
JPS5321192A (en) * | 1976-08-10 | 1978-02-27 | Takeda Chem Ind Ltd | Cephalosporin derivatives and their preparation |
US4370326A (en) * | 1977-09-13 | 1983-01-25 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and composition |
ZA793391B (en) * | 1978-07-07 | 1980-06-25 | Ciba Geigy Ag | Aminothiazole compounds |
MA18686A1 (fr) * | 1978-07-07 | 1980-10-01 | Ciba Geigy Ag | Composes aminothiazoliques |
JPS5543011A (en) * | 1978-09-20 | 1980-03-26 | Shionogi & Co Ltd | 7-halothiazolylalkoxyiminoacetamido-3-cephem compound |
GR78221B (es) * | 1980-02-01 | 1984-09-26 | Ciba Geigy Ag |
-
1981
- 1981-12-07 EP EP81810484A patent/EP0054512A3/de not_active Ceased
- 1981-12-07 GB GB08136779A patent/GB2111043B/en not_active Expired
- 1981-12-08 DD DD81235540A patent/DD208155A5/de unknown
- 1981-12-09 FI FI813946A patent/FI813946L/fi not_active Application Discontinuation
- 1981-12-10 IL IL64506A patent/IL64506A/xx unknown
- 1981-12-10 GR GR66761A patent/GR76967B/el unknown
- 1981-12-11 JP JP56198778A patent/JPS57123190A/ja active Granted
- 1981-12-11 HU HU813749A patent/HU185985B/hu unknown
- 1981-12-11 NZ NZ199255A patent/NZ199255A/en unknown
- 1981-12-11 PT PT74119A patent/PT74119B/pt unknown
- 1981-12-11 IE IE2915/81A patent/IE52008B1/en unknown
- 1981-12-11 ZA ZA818622A patent/ZA818622B/xx unknown
- 1981-12-11 ES ES507907A patent/ES507907A0/es active Granted
- 1981-12-11 AU AU78466/81A patent/AU7846681A/en not_active Abandoned
- 1981-12-11 DK DK550081A patent/DK550081A/da not_active Application Discontinuation
- 1981-12-11 NO NO814232A patent/NO814232L/no unknown
- 1981-12-11 KR KR1019810004853A patent/KR830007683A/ko unknown
-
1982
- 1982-10-16 ES ES516590A patent/ES516590A0/es active Granted
- 1982-10-16 ES ES516593A patent/ES516593A0/es active Granted
- 1982-10-16 ES ES516592A patent/ES8307820A1/es not_active Expired
- 1982-10-16 ES ES516594A patent/ES8401080A1/es not_active Expired
- 1982-10-16 ES ES516591A patent/ES516591A0/es active Granted
-
1983
- 1983-01-31 AR AR291999A patent/AR231984A1/es active
Also Published As
Publication number | Publication date |
---|---|
GR76967B (es) | 1984-09-04 |
NZ199255A (en) | 1985-08-30 |
PT74119A (de) | 1982-01-01 |
ES516594A0 (es) | 1983-11-16 |
GB2111043B (en) | 1985-02-06 |
AU7846681A (en) | 1982-06-17 |
HU185985B (en) | 1985-04-28 |
DD208155A5 (de) | 1984-03-28 |
PT74119B (de) | 1983-12-19 |
ES8303424A1 (es) | 1983-02-01 |
IE812915L (en) | 1982-06-12 |
DK550081A (da) | 1982-06-13 |
ES516592A0 (es) | 1983-08-01 |
ES8401077A1 (es) | 1983-11-16 |
NO814232L (no) | 1982-06-14 |
JPS57123190A (en) | 1982-07-31 |
ES516591A0 (es) | 1983-11-16 |
ES8401079A1 (es) | 1983-11-16 |
ES8307820A1 (es) | 1983-08-01 |
FI813946L (fi) | 1982-06-13 |
AR231984A1 (es) | 1985-04-30 |
ES516590A0 (es) | 1983-11-16 |
EP0054512A2 (de) | 1982-06-23 |
EP0054512A3 (de) | 1983-08-03 |
GB2111043A (en) | 1983-06-29 |
ZA818622B (en) | 1982-10-27 |
IL64506A (en) | 1985-05-31 |
ES516593A0 (es) | 1983-11-16 |
ES8401080A1 (es) | 1983-11-16 |
JPH0314038B2 (es) | 1991-02-25 |
ES507907A0 (es) | 1983-02-01 |
IE52008B1 (en) | 1987-05-13 |
IL64506A0 (en) | 1982-03-31 |
KR830007683A (ko) | 1983-11-04 |
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