RU2595395C2 - Способы снижения вирулицидной активности содержащих pcv-2 композиций и содержащие pcv-2 композиции с повышенной иммуногенностью - Google Patents
Способы снижения вирулицидной активности содержащих pcv-2 композиций и содержащие pcv-2 композиции с повышенной иммуногенностью Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
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- Microbiology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (5)
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| US23919209P | 2009-09-02 | 2009-09-02 | |
| US61/239,192 | 2009-09-02 | ||
| US30940810P | 2010-03-01 | 2010-03-01 | |
| US61/309,408 | 2010-03-01 | ||
| PCT/US2010/047654 WO2011028888A2 (en) | 2009-09-02 | 2010-09-02 | Methods of reducing virucidal activity in pcv-2 compositions and pcv-2 compositions with an improved immunogenicity |
Publications (2)
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| RU2012112636A RU2012112636A (ru) | 2013-10-27 |
| RU2595395C2 true RU2595395C2 (ru) | 2016-08-27 |
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| RU2012112636/10A RU2595395C2 (ru) | 2009-09-02 | 2010-09-02 | Способы снижения вирулицидной активности содержащих pcv-2 композиций и содержащие pcv-2 композиции с повышенной иммуногенностью |
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| IN (1) | IN2012DN01898A (enExample) |
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Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833707B2 (en) | 2004-12-30 | 2010-11-16 | Boehringer Ingelheim Vetmedica, Inc. | Methods of overexpression and recovery of porcine circovirus type 2 ORF2 |
| UA95602C2 (ru) | 2004-12-30 | 2011-08-25 | Берингер Ингельхейм Ветмедика, Инк. | Иммуногенная композиция цвс2 и способы приготовления такой композиции |
| US8834891B2 (en) | 2005-03-14 | 2014-09-16 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions comprising Lawsonia intracellularis |
| PL2371383T3 (pl) | 2005-12-29 | 2016-01-29 | Boehringer Ingelheim Vetmedica Inc | Zastosowanie kompozycji immunogennej do zmniejszania objawów klinicznych u świń |
| US20080226669A1 (en) | 2005-12-29 | 2008-09-18 | Boehringer Ingelheim Vetmedica, Inc. | Multivalent pcv2 immunogenic compositions and methods of producing such compositions |
| WO2008073464A2 (en) | 2006-12-11 | 2008-06-19 | Boehringer Ingelheim Vetmedica, Inc. | Effective method of treatment of porcine circovirus and lawsonia intracellularis infections |
| ES2625460T5 (es) | 2006-12-15 | 2020-11-04 | Boehringer Ingelheim Animal Health Usa Inc | Tratamiento de cerdos seropositivos en anticuerpo anti-PCV2 con antígeno de PCV2 |
| EP1941903A1 (en) | 2007-01-03 | 2008-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Prophylaxis and treatment of PRDC |
| EP1958644A1 (en) | 2007-02-13 | 2008-08-20 | Boehringer Ingelheim Vetmedica Gmbh | Prevention and treatment of sub-clinical pcvd |
| US7829274B2 (en) | 2007-09-04 | 2010-11-09 | Boehringer Ingelheim Vetmedica, Inc. | Reduction of concomitant infections in pigs by the use of PCV2 antigen |
| EP2242511A4 (en) | 2008-01-23 | 2012-10-24 | Boehringer Ingelheim Vetmed | IMMUNOGENIC COMPOSITIONS OF MYCOPLASMA HYOPNEUMONIAE PCV2, AND METHODS FOR PRODUCING SUCH COMPOSITIONS |
| TWI627281B (zh) | 2009-09-02 | 2018-06-21 | 百靈佳殷格翰家畜藥品公司 | 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物 |
| CN103102397A (zh) * | 2011-11-09 | 2013-05-15 | 韩健宝 | 预防和治疗pcv-2病毒的肽核酸及其制剂 |
| CN105246505A (zh) * | 2013-04-30 | 2016-01-13 | 勃林格殷格翰动物保健公司 | PCV2a亚型(PCV2a)的ORF2蛋白用于交叉保护中的用途 |
| ES2882374T3 (es) | 2013-05-08 | 2021-12-01 | Pharmgate Biologics Inc | Vacuna para PCV2 y micoplasma |
| DK3052516T3 (da) | 2013-10-02 | 2020-03-23 | Boehringer Ingelheim Animal Health Usa Inc | PCV2-ORF2-proteinvariant og viruslignende partikler sammensat deraf |
| NZ743977A (en) * | 2015-12-28 | 2020-01-31 | Boehringer Ingelheim Animal Health Usa Inc | M hyo multivalent vaccine and uses thereof |
| PL3534939T3 (pl) * | 2016-11-03 | 2023-06-12 | Boehringer Ingelheim Vetmedica Gmbh | Szczepionka przeciw parwowirusowi świń i wirusowi zespołu rozrodczo-oddechowego świń oraz sposoby ich wytwarzania |
| CN119488586A (zh) * | 2018-03-26 | 2025-02-21 | 勃林格殷格翰动物保健美国有限公司 | 制备免疫原性组合物的方法 |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
| US12537071B1 (en) | 2020-07-22 | 2026-01-27 | David Gordon Bermudes | Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins |
| CN113957059B (zh) * | 2021-11-26 | 2023-08-22 | 山东滨州沃华生物工程有限公司 | 一步柱层析工艺精纯猪蓝耳病毒的方法 |
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| WO2006072065A2 (en) * | 2004-12-30 | 2006-07-06 | Boehringer Ingelheim Vetmedica, Inc. | Pcv2 immunogenic compositions and methods of producing such compositions |
| WO2007076520A2 (en) * | 2005-12-29 | 2007-07-05 | Boehringer Ingelheim Vetmedica, Inc. | Multivalent pcv2 immunogenic compositions and methods of producing such compositions |
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-
2012
- 2012-03-01 CL CL2012000562A patent/CL2012000562A1/es unknown
- 2012-03-09 CO CO12041859A patent/CO6511229A2/es unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2006072065A2 (en) * | 2004-12-30 | 2006-07-06 | Boehringer Ingelheim Vetmedica, Inc. | Pcv2 immunogenic compositions and methods of producing such compositions |
| WO2007076520A2 (en) * | 2005-12-29 | 2007-07-05 | Boehringer Ingelheim Vetmedica, Inc. | Multivalent pcv2 immunogenic compositions and methods of producing such compositions |
Non-Patent Citations (1)
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| С.Н.КАРТАШОВ и др., Иммуногистохимическое исследование лимфоузлов при цирковирусной инфекции свиней, Ветеринарная патология, 2008, N4, стр.26-31. * |
Also Published As
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| RU2012112636A (ru) | 2013-10-27 |
| TW201120212A (en) | 2011-06-16 |
| CL2012000562A1 (es) | 2012-10-12 |
| CN102573899A (zh) | 2012-07-11 |
| JP2013503893A (ja) | 2013-02-04 |
| KR101773754B1 (ko) | 2017-09-01 |
| CA2772928C (en) | 2019-01-08 |
| AR078253A1 (es) | 2011-10-26 |
| CA2772928A1 (en) | 2011-03-10 |
| AU2010289431B2 (en) | 2017-02-02 |
| EP2473189B1 (en) | 2017-11-15 |
| US9561270B2 (en) | 2017-02-07 |
| MY165831A (en) | 2018-05-17 |
| SG178595A1 (en) | 2012-04-27 |
| US20110059126A1 (en) | 2011-03-10 |
| ES2657812T3 (es) | 2018-03-07 |
| BR112012004698A2 (pt) | 2016-11-29 |
| EP2473189A2 (en) | 2012-07-11 |
| BR112012004698B1 (pt) | 2022-03-08 |
| MX2012002329A (es) | 2012-04-10 |
| CO6511229A2 (es) | 2012-08-31 |
| TWI627281B (zh) | 2018-06-21 |
| KR20120104514A (ko) | 2012-09-21 |
| JP5921435B2 (ja) | 2016-05-24 |
| DK2473189T3 (da) | 2018-01-29 |
| MX340760B (es) | 2016-07-21 |
| WO2011028888A2 (en) | 2011-03-10 |
| IN2012DN01898A (enExample) | 2015-07-24 |
| CN107412760A (zh) | 2017-12-01 |
| SG10201405406VA (en) | 2014-10-30 |
| WO2011028888A3 (en) | 2011-06-23 |
| AU2010289431A1 (en) | 2012-03-08 |
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