DE69214657T4 - Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas) - Google Patents

Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas)

Info

Publication number
DE69214657T4
DE69214657T4 DE1992614657 DE69214657T DE69214657T4 DE 69214657 T4 DE69214657 T4 DE 69214657T4 DE 1992614657 DE1992614657 DE 1992614657 DE 69214657 T DE69214657 T DE 69214657T DE 69214657 T4 DE69214657 T4 DE 69214657T4
Authority
DE
Germany
Prior art keywords
suas
antibody
diagnostic method
vaccine against
monoclonal antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1992614657
Other languages
English (en)
Other versions
DE69214657D1 (de
DE69214657T3 (de
DE69214657T2 (de
Inventor
James Edward Collins
David Allen Benfield
Danny W Chladek
Louis L Harris
David E Gorcyca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota
University of South Dakota
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Boehringer Ingelheim Vetmedica Inc
University of Minnesota
University of South Dakota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27419388&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69214657(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica Inc, University of Minnesota, University of South Dakota filed Critical Boehringer Ingelheim Vetmedica Inc
Application granted granted Critical
Publication of DE69214657T3 publication Critical patent/DE69214657T3/de
Publication of DE69214657T4 publication Critical patent/DE69214657T4/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/00034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE1992614657 1991-08-26 1992-08-17 Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas) Expired - Lifetime DE69214657T4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74983991A 1991-08-26 1991-08-26
US76071391A 1991-09-16 1991-09-16
US86044492A 1992-03-30 1992-03-30
PCT/US1992/006873 WO1993003760A1 (en) 1991-08-26 1992-08-17 Sirs vaccine and diagnosis method

Publications (2)

Publication Number Publication Date
DE69214657T3 DE69214657T3 (de) 2001-05-03
DE69214657T4 true DE69214657T4 (de) 2003-07-17

Family

ID=27419388

Family Applications (3)

Application Number Title Priority Date Filing Date
DE1992918970 Pending DE601062T1 (de) 1991-08-26 1992-08-17 Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas).
DE1992614657 Expired - Lifetime DE69214657T2 (de) 1991-08-26 1992-08-17 Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas)
DE1992614657 Expired - Lifetime DE69214657T4 (de) 1991-08-26 1992-08-17 Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE1992918970 Pending DE601062T1 (de) 1991-08-26 1992-08-17 Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas).
DE1992614657 Expired - Lifetime DE69214657T2 (de) 1991-08-26 1992-08-17 Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas)

Country Status (15)

Country Link
US (2) US5683865A (de)
EP (1) EP0601062B2 (de)
JP (4) JP3473700B2 (de)
KR (1) KR100241221B1 (de)
AT (1) ATE144144T1 (de)
AU (1) AU2508492A (de)
CA (1) CA2116348C (de)
DE (3) DE601062T1 (de)
DK (1) DK0601062T4 (de)
ES (1) ES2065303T5 (de)
GR (3) GR940300089T1 (de)
HK (1) HK1005014A1 (de)
HU (1) HU217105B (de)
SG (1) SG43852A1 (de)
WO (1) WO1993003760A1 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103460C (en) 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US6080570A (en) * 1991-08-26 2000-06-27 Boehringer Ingelheim Vetmedica, Inc. Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
DK0601062T4 (da) * 1991-08-26 2001-03-14 Univ Minnesota SIRS-vaccine og diagnosefremgangsmåde
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
US5846805A (en) * 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US6982160B2 (en) * 1991-08-26 2006-01-03 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions that include SIRS virus
ES2083764T5 (es) * 1991-10-14 2009-04-01 Intervet International Bv Vacuna para el sindrome respiratorio reproductivo porcino (srrp) y diagnostico.
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6251397B1 (en) * 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
SK98695A3 (en) * 1993-02-08 1996-11-06 Bayer Ag Process for growing porcine reproductive and respiratory syndrome virus and its use in vaccines
EP0676467B1 (de) * 1994-04-11 2001-10-04 Akzo Nobel N.V. Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Schweins
DK53595A (da) * 1994-05-13 1995-11-14 Iberica Cyanamid Rekombinante PRRSV-proteiner, diagnostiske kits og vaccine indeholdende sådanne rekombinante PRRSV-proteiner
ES2262142T3 (es) * 1994-08-05 2006-11-16 Regents Of The University Of Minnesota Secuencia virica de nucleotidos de vr-2332 y metodos de uso.
ES2102971B1 (es) * 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
EP0839912A1 (de) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
PT980387E (pt) 1997-05-06 2007-07-31 Boehringer Ingelheim Vetmed Sítios antigénicos de prrsv que identificam sequências peptídicas do vírus prrsv para utilização em vacinas ou em ensaios de diagnóstico
US7691389B2 (en) 1998-12-22 2010-04-06 Pfizer Inc Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7618797B2 (en) 1998-12-22 2009-11-17 Pfizer Inc Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
US7132106B2 (en) 1998-12-22 2006-11-07 Pfizer Inc. Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
CA2440933A1 (en) 1998-12-22 2000-06-22 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
CA2366072C (en) 1999-03-08 2007-07-10 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
CA2370372C (en) * 1999-04-22 2009-02-24 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
EP1255815B1 (de) * 2000-02-08 2006-07-19 Regents Of The University Of Minnesota Virus des porzinen reproduktiven und respiratorischen syndroms und dessen verwendung
US6841364B2 (en) * 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
US20080268426A1 (en) * 2004-06-18 2008-10-30 Regents Of The University Of Minnesota Identifying virally infected and vaccinated organisms
JP2008503727A (ja) * 2004-06-18 2008-02-07 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ ウイルス感染した生物およびワクチン接種した生物の同定
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
WO2006074986A2 (en) 2005-01-13 2006-07-20 Boehringer Ingelheim Vetmedica Gmbh Prrs vaccines
MX2007015849A (es) * 2005-06-24 2008-02-22 Univ Minnesota Virus del sindrome respiratorio y reproductivo porcino, clones infecciosos, mutantes de los mismos, y metodos de uso.
US7666585B2 (en) * 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
CN101848995A (zh) * 2007-06-25 2010-09-29 南达科他州立大学 重组的北美1型猪繁殖与呼吸综合征病毒及使用方法
WO2010025109A1 (en) * 2008-08-25 2010-03-04 Boehringer Ingelheim Vetmedia, Inc. Vaccine against highly pathogenic porcine reproductive and respiratory syndrome (hp prrs)
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
UA108902C2 (uk) 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
CA2827337C (en) 2011-02-17 2019-07-09 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
HUE027731T2 (en) 2011-02-17 2016-10-28 Boehringer Ingelheim Vetmedica Gmbh New European PRRSV strain
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
CN104302316A (zh) 2012-05-17 2015-01-21 佐蒂斯有限责任公司 在断奶之前对抗猪繁殖与呼吸综合征(prrs)病毒的有效疫苗接种
EP2968513A2 (de) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Prrs-virus, zusammensetzungen, impfstoff und verfahren zur verwendung
KR101502360B1 (ko) * 2013-03-20 2015-03-25 주식회사 옵티팜 신규한 국내형 돼지생식기호흡기증후군 바이러스
EP3344289B1 (de) 2015-08-31 2020-01-29 Boehringer Ingelheim Vetmedica GmbH Pestivirusimpfstoffe gegen kongenitalen tremor
US10188725B2 (en) 2015-12-14 2019-01-29 Elanco Us Inc. Hybrid core feline vaccines
EP3554537A2 (de) 2016-12-14 2019-10-23 Zoetis Services LLC Wirksame impfung gegen europäische stämme des virus des porcinen reproduktiven und respiratorischen syndrom (prrs) vor der entwöhnung
WO2020206452A1 (en) 2019-04-04 2020-10-08 Boehringer Ingelheim Animal Health USA Inc. Porcine circovirus type 3 (pcv3) vaccines, and production and uses thereof
RU2731474C1 (ru) * 2020-02-26 2020-09-03 Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии" (ФГБНУ "ВНИВИПФиТ") Способ диагностики скрыто протекающего воспалительного процесса в репродуктивных органах свиноматок
AU2021311726A1 (en) 2020-07-24 2023-02-09 Boehringer Ingelheim Animal Health USA Inc. Combination porcine vaccine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD145705A1 (de) * 1979-08-31 1981-01-07 Peter Solisch Herstellungsverfahren von organspezifischen retrovirusimmunpraeparaten fuer prophylaxe,therapie und diagnostik
ZA864879B (en) * 1985-07-08 1987-03-25 Wallone Region Vaccines and diagnostics derived from boving diarrhoea virus
NZ222465A (en) * 1986-11-07 1992-11-25 Pasteur Institut Nanb (non a, non b hepatitis viral) antigen
DE3833925A1 (de) * 1988-03-11 1989-09-21 Inst Angewandte Biotechnologie Verfahren und herstellung von virus und viralem antigen und vorrichtung hierzu
CA2103460C (en) * 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US6042830A (en) † 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
DK0601062T4 (da) * 1991-08-26 2001-03-14 Univ Minnesota SIRS-vaccine og diagnosefremgangsmåde

Also Published As

Publication number Publication date
HU217105B (hu) 1999-11-29
DE69214657D1 (de) 1996-11-21
DE601062T1 (de) 1995-05-18
EP0601062B2 (de) 2000-12-13
DK0601062T4 (da) 2001-03-14
JP2005336203A (ja) 2005-12-08
WO1993003760A1 (en) 1993-03-04
GR3022194T3 (en) 1997-03-31
SG43852A1 (en) 1997-11-14
ES2065303T3 (es) 1997-02-16
JP3473700B2 (ja) 2003-12-08
ES2065303T5 (es) 2001-05-01
CA2116348A1 (en) 1993-03-04
JP3566279B2 (ja) 2004-09-15
JPH06510288A (ja) 1994-11-17
US5683865A (en) 1997-11-04
KR100241221B1 (ko) 2000-03-02
ES2065303T1 (es) 1995-02-16
ATE144144T1 (de) 1996-11-15
GR940300089T1 (en) 1994-12-30
EP0601062B1 (de) 1996-10-16
JP2004097214A (ja) 2004-04-02
HK1005014A1 (en) 1998-12-18
DE69214657T3 (de) 2001-05-03
US5677429A (en) 1997-10-14
JP3722794B2 (ja) 2005-11-30
GR3035442T3 (en) 2001-05-31
DK0601062T3 (da) 1997-03-24
JP3878647B2 (ja) 2007-02-07
EP0601062A1 (de) 1994-06-15
HU9400560D0 (en) 1994-05-30
HUT69800A (en) 1995-09-28
DE69214657T2 (de) 1997-04-17
AU2508492A (en) 1993-03-16
CA2116348C (en) 2001-07-03
JP2003252791A (ja) 2003-09-10

Similar Documents

Publication Publication Date Title
DE69214657D1 (de) Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas)
Czerkinsky et al. A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells
Tarkowski et al. Simultaneous induction of rheumatoid factor-and antigen-specific antibody-secreting cells during the secondary immune response in man.
KR870003195A (ko) 단일클론 항체를 이용한 그램 네가티브 박테리아 감염증의 검진 방법
KR910016346A (ko) 광견병 바이러스에 대한 사람 모노클로날 항체, 이의 제조방법 및 용도
CA2331088A1 (en) Urinary tumor associated antigen, antigenic subunits uses and methods of detection
DE69333076D1 (de) Test und behandlung von demyelinierenden krankheiten wie multiple sklerosis
EP0352722A3 (de) Bindungstests für Adenocarcinoma-Antigen und Reagenzien
DE69433378D1 (de) Humane b-lymphoblastoiden zellinie welche anti-gangliosid-antikörper sekretiert
DK392387D0 (da) Monoklonalt antistrof til diagnostisk anvendelse og fremgangsmaade til fremstilling af et saadan antistof
Costa et al. Specificities of antinuclear antibodies detected in dogs with systemic lupus erythematosus
ATE61735T1 (de) Fuer endotoxine spezifische antikoerper.
Spear et al. Hereditary nephritis with nerve deafness: Immunofluorescent studies on the kidney, with a consideration of discordant immunoglobulin-complement immunofluorescent reactions
Olsen et al. Unique antigenic determinants (idiotypes) used as markers in a patient with macroglobulinemia and urticaria: similar idiotypes demonstrated in the skin and on peripheral blood lymphocytes
EP0255497A2 (de) Protein L und ihre Untereinheiten, mit immunglobulinbindender Aktivität, Verfahren zur Herstellung, Reagenssatz, pharmazeutische Zubereitung und ein Peptococcus-magnus-Stamm
FI922666A0 (fi) Diagnostiskt foerfarande.
DE3587542D1 (de) Verfahren zur Diagnose in vitro von menschlichen Cytomegalovirusinfektionen und Anwendung von monoklonalen Antikörpern gegen Cytomegaloviren, die mit einer cytomegalovirusinduzierten Proteinkinase reagieren.
FI86255B (fi) Monoklonal antiurokinase-antikropp, den innehaollande matris och biokemiska testpackningar, i vilka den anvaendes.
FR2359851A1 (fr) Antigene et anticorps pour un essai de determination immunologique de la thymopoietine, et leur application
ATE118032T1 (de) Monoklonale antikörper und diagnoseverfahren für phytophthora-infektionen.
ISHII et al. Immunodiagnosis of Human Cancer
Shigeta et al. MONOCLONAL ANTI-IDIOTYPIC ANTIBODY AGAINST HUMAN MONOCLONAL SPERM IMMOBILIZATION ANTIBODY H6-3C4.
Friberg Comparison of immunoglobulin class between immunobead reactive antibodies and sperm agglutinating antibodies
DK182188A (da) Humant tumorassocieret antigen
KR970073606A (ko) 항 인체 인터루킨-6 항체 및 이를 이용한 인체 인터루킨-6의 검정