UA95602C2 - Иммуногенная композиция цвс2 и способы приготовления такой композиции - Google Patents

Иммуногенная композиция цвс2 и способы приготовления такой композиции

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Publication number
UA95602C2
UA95602C2 UAA200708620A UAA200708620A UA95602C2 UA 95602 C2 UA95602 C2 UA 95602C2 UA A200708620 A UAA200708620 A UA A200708620A UA A200708620 A UAA200708620 A UA A200708620A UA 95602 C2 UA95602 C2 UA 95602C2
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reading frame
open reading
expressed
protein
cells
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UAA200708620A
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English (en)
Ukrainian (uk)
Inventor
Марк ЭЙЧМЕЙЕР
Грег Нитзель
Меррилл Шаффер
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Берингер Ингельхейм Ветмедика, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50836643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA95602(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of UA95602C2 publication Critical patent/UA95602C2/ru

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    • AHUMAN NECESSITIES
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    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
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    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
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    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

Изобретение относится к способу восстановления протеина, экспрессированного открытой рамкой считывания 2, из цирковируса свиньи 2. Способ включает этапы трансфектирования рекомбинантного бакуловируса, который содержит открытую рамку считывания 2, который кодирует последовательности в клетках, помещенных в ростовую среду, которая заставляет вирус экспрессировать открытую рамку считывания 2, и восстановление экспресированного протеина в супернатанте. Это восстановление происходит приблизительно через 5 дней после инфицирования клеток, чтобы достаточное количество рекомбинированного протеина экспрессировалось и секретировалось клеткой в питательную среду. Такие способы предохраняют от дорогих и трудоемких методик экстракции, которые нужны для выделения и восстановления рекомбинантного протеина в клетках.
UAA200708620A 2004-12-30 2005-12-29 Иммуногенная композиция цвс2 и способы приготовления такой композиции UA95602C2 (ru)

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US64051004P true 2004-12-30 2004-12-30

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UA95602C2 true UA95602C2 (ru) 2011-08-25

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UAA200708620A UA95602C2 (ru) 2004-12-30 2005-12-29 Иммуногенная композиция цвс2 и способы приготовления такой композиции
UAA201015883A UA107177C2 (xx) 2004-12-30 2010-12-29 Імуногенна композиція цвс2 та спосіб приготування такої композиції

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UAA201015883A UA107177C2 (xx) 2004-12-30 2010-12-29 Імуногенна композиція цвс2 та спосіб приготування такої композиції

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US (2) US9919041B2 (ru)
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Families Citing this family (5)

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UA95602C2 (ru) * 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
CN103536914B (zh) 2005-12-29 2015-11-11 贝林格尔.英格海姆维特梅迪卡有限公司 多价pcv2免疫原性组合物和制备此类组合物的方法
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