RU2559540C2 - Дважды ацилированные производные glp-1 - Google Patents

Дважды ацилированные производные glp-1 Download PDF

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RU2559540C2
RU2559540C2 RU2012128547/10A RU2012128547A RU2559540C2 RU 2559540 C2 RU2559540 C2 RU 2559540C2 RU 2012128547/10 A RU2012128547/10 A RU 2012128547/10A RU 2012128547 A RU2012128547 A RU 2012128547A RU 2559540 C2 RU2559540 C2 RU 2559540C2
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ethoxy
acetyl
amino
glp
carboxy
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RU2012128547/10A
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Russian (ru)
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RU2012128547A (ru
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Патрик Уилльям ГЭРИБЭЙ
Яне СПЕТСЛЕР
Янош Тибор КОДРА
Ларс ЛИНДЕРОТ
Еспер ЛАУ
Пер ЗАУЭРБЕРГ
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Ново Нордиск А/С
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/605—Glucagons

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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
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  • Molecular Biology (AREA)
  • Toxicology (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
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  • Urology & Nephrology (AREA)
RU2012128547/10A 2009-12-16 2010-12-16 Дважды ацилированные производные glp-1 RU2559540C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09179390.1 2009-12-16
EP09179390 2009-12-16
US28860109P 2009-12-21 2009-12-21
US61/288,601 2009-12-21
PCT/EP2010/069932 WO2011080103A1 (en) 2009-12-16 2010-12-16 Double-acylated glp-1 derivatives

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RU2012128547A RU2012128547A (ru) 2014-01-27
RU2559540C2 true RU2559540C2 (ru) 2015-08-10

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US (4) US20120329711A1 (cg-RX-API-DMAC10.html)
EP (4) EP3000482B1 (cg-RX-API-DMAC10.html)
JP (5) JP6006118B2 (cg-RX-API-DMAC10.html)
KR (1) KR101817607B1 (cg-RX-API-DMAC10.html)
CN (6) CN104327182B (cg-RX-API-DMAC10.html)
AU (1) AU2010338387B2 (cg-RX-API-DMAC10.html)
BR (1) BR112012014475A8 (cg-RX-API-DMAC10.html)
CA (1) CA2784757A1 (cg-RX-API-DMAC10.html)
DK (1) DK2513140T3 (cg-RX-API-DMAC10.html)
ES (2) ES2625735T3 (cg-RX-API-DMAC10.html)
HU (1) HUE027229T2 (cg-RX-API-DMAC10.html)
IL (1) IL219945A (cg-RX-API-DMAC10.html)
MX (1) MX2012006634A (cg-RX-API-DMAC10.html)
PL (1) PL2513140T3 (cg-RX-API-DMAC10.html)
PT (1) PT2513140E (cg-RX-API-DMAC10.html)
RU (1) RU2559540C2 (cg-RX-API-DMAC10.html)
TW (1) TWI484974B (cg-RX-API-DMAC10.html)
WO (3) WO2011080102A2 (cg-RX-API-DMAC10.html)
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